logo
CanyamAI summaries for academic research
language
MobileMobile
  • Phone FeatureWeChat Mini Program
EnglishEnglish
noticeNotice
BlogBlog
delete
arrow
Back
K

Kevan M. Shokat

University of California

115H-index
740Paper Count
5.5WCitation Count
Published Papers 244
Publication Date
logo
Acute rapamycin treatment reveals distinct mechanisms of dysfunction in a maternal inflammation mouse model
errNature Communications
IF15.7
err2026-07-23
err0
errOAAI
errJE Le Belle; M. C. Condro; C. Cepeda; KD Oikonomou; K. Tessema; L. Dudley; J. Schoenfield; R. Kawaguchi; D. Geschwind; AJ Silva; Z. Zhang; K. Shokat; NG Harris; HI Kornblum
errShare
errSave
Single-cell transcriptomic unveils tumor-mediated reprogramming of neutrophils and their unique vulnerability that inhibits metastasis
errScience Advances
IF12.5
err2026-07-15
err0
errOAAI
errWilliam Putzbach; Maria P. Zappia; Ahmed Magdy; Jing Li; Veronique Nogueira; Kevin Lou; Kevan M. Shokat; Abul B. M. M. K. Islam; Maxim Frolov; Nissim Hay
errShare
errSave
Benzoxaboroles Are Structurally Unique Binders of Eukaryotic Translation Initiation Factor 4E
errJournal of the American Chemical Society
IF15.6
err2026-07-09
err0
errOAAI
errJoshua B. Combs; D. Matthew Peacock; Gregory B. Craven; Sungwon Jung; Ying Chen; Sang M. Le; Jack Taunton; Kevan M. Shokat
errShare
errSave
Single-Sequence Deep Learning Delivers Crystal-Quality Models of Covalent K-Ras G12 Hotspot Complexes
errIUBMB Life
IF3.2
err2026-06-13
err0
errOAAI
errSungwon Jung; Qinheng Zheng; Kevan M. Shokat
errShare
errSave
Targeting the Protein–Membrane Interface Enables Design of Long-Acting CFTR Potentiators
errACS Chemical Biology
IF3.8
err2026-04-28
err0
errOAAI
errJohannes Morstein; Jonathan Borowsky; Shenghui Hu; YooJin Sheen; Victoria Nisoli; Tzyh-Chang Hwang; Michael Grabe; Kevan M. Shokat
errShare
errSave
The GENEVA platform models tumor mosaicism to reveal variations of responses to KRAS inhibitors and identify improved drug combinations
errNature Cancer
IF28.5
err2026-02-24
err0
errOAAI
errJohnny X. Yu; Jung Min Suh; Katerina D. Popova; Kristle Garcia; Tanvi Joshi; Bruce Culbertson; Jessica B. Spinelli; Vishvak Subramanyam; Kevin Lou; Trey Charbonneau; Kevan M. Shokat; Jonathan Weissman; Hani Goodarzi
errShare
errSave
Genome-scale CRISPR screens identify PTGES3 as a direct modulator of androgen receptor function in advanced prostate cancer
errNature Genetics
IF29
err2025-11-05
err0
errOAAI
errHaolong Li; James E. Melnyk; Becky Xu Hua Fu; Raunak Shrestha; Meng Zhang; Martin Sjöström; Siyu Feng; Jasmine A. Anderson; Wanting Han; Lisa N. Chesner; Hyun Jin Shin; Tatyanah Farsh; Humberto J. Suarez; Seema Nath; Jonathan Chou; Rajdeep Das; Emily A. Egusa; Marsha Calvert; Audrey Kishishita; Abhilash Barpanda; Jun Zhu; Ashutosh Maheshwari; William S. Chen; Mohammed Alshalalfa; Aidan Winters; Junjie T. Hua; Tianyi Liu; Elai Davicioni; Arun P. Wiita; Bradley A. Stohr; Javed Siddiqui; Bo Huang; Eric J. Small; Kevan M. Shokat; Peter S. Nelson; David A. Quigley; Elizabeth V. Wasmuth; Luke A. Gilbert; Felix Y. Feng
errShare
errSave
Bitopic inhibitors of mTORC1 cooperate with inhibitors of mitogen-activated protein kinase kinase to drive cytotoxicity in glioblastoma
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errFan, Qiwen; Koach, Jessica; Luo, Karen; Clark, Sydney; Reddy, Shruthi; Ozawa, Tomoko; Wang, Linyu; Yoda, Hiroyuki; Sale, Matthew; Mccormick, Frank; Raleigh, David R.; Gustafson, William C.; Meyerowitz, Justin; Singh, Mallika; Berger, Mitchel; Shokat, Kevan M.; Weiss, William A.
errShare
errSave
Deazaguanylation is a nucleobase-protein conjugation required for type IV CBASS immunity
errScience
IF45.8
err2025-09-25
err0
errOAAI
errDouglas R. Wassarman; Patrick Pfaff; Joao A. Paulo; Steven P. Gygi; Kevan M. Shokat; Philip J. Kranzusch
errShare
errSave
Introduction: Drugging the Undruggable
errChemical Reviews
IF55.8
err2025-07-23
err0
PREAI
errZiyang Zhang; Kevan M. Shokat
errShare
errSave
Promise and Challenge of β-Lactone Electrophiles to Target Aspartate 12 of Mutant KRASG12D
errJournal of Medicinal Chemistry
IF6.8
err2025-07-10
err0
PREAI
errBalázs Budai; Andrea Vaupel; Callum J. Dickson; Kim S. Beyer; Daniel A. Guthy; Nils Ostermann; Lynn M. McGregor; Ruben De Kanter; Andreas Weiss; Markus Linder; Emine Sager; Claudio Bomio-Confaglia; Rupert Proctor; Catherine Leblanc; Jun Yuan; Simona Cotesta; Rainer Wilcken; Aaron D. Danilack; Francisco Garcia; Phuong Rogemoser; Malika Kazic-Legueux; Ziyang Zhang; Qinheng Zheng; Kevan M. Shokat; Saskia M. Brachmann; Veronika Ehmke
errShare
errSave
Subcellular activation of β- adrenergic receptors using a spatially restricted antagonist
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-09-27
err0
errOAAI
errLiccardo, Federica; Morstein, Johannes; Lin, Ting-Yu; Pampel, Julius; Lang, Di; Shokat, Kevan M.; Irannejad, Roshanak
errShare
errSave
Direct RAS inhibitors turn 10
errNATURE CHEMICAL BIOLOGY
IF13.7
err2024-07-26
err1
PREAI
errOstrem, Jonathan M. L.; Peters, Ulf; Shokat, Kevan M.
errShare
errSave
Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D
errNATURE CHEMICAL BIOLOGY
IF13.7
err2024-03-05
err23
errOAAI
errZheng, Qinheng; Zhang, Ziyang; Guiley, Keelan Z.; Shokat, Kevan M.
errShare
errSave
Mutant-selective, covalent inhibitors of K-Ras(G12D)
errCANCER RESEARCH
IF16.6
err2024-01-16
err0
PREAI
errZheng, Qinheng; Zhang, Ziyang; Guiley, Keelan; Shokat, Kevan
errShare
errSave
Development of covalent inhibitors targeting Ras Q61 hotspot mutants
errCANCER RESEARCH
IF16.6
err2024-01-16
err0
PREAI
errPampel, Julius; Morstein, Johannes; Zheng, Qinheng; Peacock, David M.; Shokat, Kevan M.
errShare
errSave
Nanomolar Protein Thermal Profiling with Modified Cyanine Dyes
errANALYTICAL CHEMISTRY
IF6.7
err2023-12-07
err1
errOAAI
errMalakoutikhah, Morteza; Mahran, Randa; Gooran, Negin; Masoumi, Ahmadreza; Lundell, Katri; Liljeblad, Arto; Guiley, Keelan; Dai, Shizhong; Zheng, Qinheng; Zhu, Lawrence; Shokat, Kevan M.; Kopra, Kari; Harma, Harri
errShare
errSave
Direct Modulators of K-Ras-Membrane Interactions
errACS CHEMICAL BIOLOGY
IF3.8
err2023-08-14
err7
errOAAI
errMorstein, Johannes; Shrestha, Rebika; Van, Que N.; Lopez, Cesar A.; Arora, Neha; Tonelli, Marco; Liang, Hong; Chen, De; Zhou, Yong; Hancock, John F.; Stephen, Andrew G.; Turbyville, Thomas J.; Shokat, Kevan M.
errShare
errSave
mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching
errCELL REPORTS
IF6.9
err2023-08-01
err10
errOAAI
errShin, Sejeong; Han, Min-Joon; Jedrychowski, Mark P.; Zhang, Ziyang; Shokal, Kevan M.; Plas, David R.; Dephoure, Noah; Yoon, Sang-Oh
errShare
errSave
Genome-wide CRISPR screens identify PTGES3 as a druggable AR modulator
errCANCER RESEARCH
IF16.6
err2023-06-02
err0
PREAI
errLi, Haolong; Melnyk, James E.; Fu, Becky Xu Hua; Feng, Siyu; Sjostrom, Martin; Shrestha, Raunak; Zhang, Meng; Chesner, Lisa N.; Shin, Hyun Jin; Calvert, Marsha; Chou, Jonathan; Das, Rajdeep; Egusa, Emily A.; Winters, Aidan; Zhu, Jun; Maheshwari, Ashutosh; Hua, Junjie T.; Alshalalfa, Mohammed; Chen, William S.; Stohr, Bradley A.; Siddiqui, Javed; Huang, Bo; Small, Eric J.; Quigley, David A.; Shokat, Kevan M.; Gilbert, Luke A.; Feng, Felix Y.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
R
Richard A. Flavell
H-index: 246 · Papers: 1.5K
G
Gordon B. Mills
H-index: 231 · Papers: 3.5K
L
Lewis C. Cantley
H-index: 214 · Papers: 1.4K
S
Steven P. Gygi
H-index: 195 · Papers: 1.0K
M
Michael A. Matthay
H-index: 169 · Papers: 1.3K
View more