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Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras Signaling Zhang, Ruirui; Huetzen, Maxim A.; Binici, Aylin; Martin-Gago, Pablo; Gasper, Raphael; Rudashevskaya, Elena; Liu, Jie; Nagaraju, Chinta; Reckzeh, Elena S.; Stuedle, Alana S. T.; Hopff, Ann-Sophie; Mesaros, Andrea; Unger, Anke; Thelen, Melanie; Janning, Petra; Reinhardt, H. Christian; Ziegler, Slava; Jachimowicz, Ron D.; Waldmann, Herbert Share Save
Overcoming Ligand Discovery Challenges: Developing Peptide-Based Tracers for SPSB2 Lenz, Christopher; Elson, Lewis; Dopfer, Johannes; Farges, Frederic; Kramer, Andreas; Lohr, Frank; Muller, Susanne; Gueret, Stephanie M.; Waldmann, Herbert; Dotsch, Volker; Saxena, Krishna; Knapp, Stefan Share Save
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Pseudo-Natural Products Inspired by Aspidospermidine-, Strychnos-, and Koumine Monoterpene Indole Alkaloids Reveal Pyrimidine Biosynthesis Inhibitors Biswas, Animesh; Greiner, Luca C.; Bonowski, Jana; Pahl, Axel; Sievers, Sonja; Schmidt, Annika; Strohmann, Carsten; Ziegler, Slava; Grigalunas, Michael; Waldmann, Herbert Share Save
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An Indole Dearomatization Strategy for the Synthesis of Pseudo-Natural Products Hoock, Joseph G. F.; Burhop, Annina; Greiner, Luca C.; Schoelermann, Beate; Guita, Celine Da Cruz Lopes; Liu, Jie; Bag, Sukdev; Pahl, Axel; Sievers, Sonja; Scheel, Rebecca; Strohmann, Carsten; Ziegler, Slava; Grigalunas, Michael; Waldmann, Herbert Share Save
Identification of Natural Killer Cell Enhancers Through Mimicking of the Tumor Microenvironment Binici, Aylin; Hennes, Elisabeth; Koska, Sandra; Niemann, Jens Alexander; Reich, Alisa; Pfaff, Christiane; Sievers, Sonja; Kahnt, Astrid Stefanie; Thomas, Dominique; Ziegler, Slava; Watzl, Carsten; Waldmann, Herbert Share Save
Thoughts for the future Alkhalaf, Lona M.; Arrowsmith, Cheryl; Balskus, Emily P.; Bergamini, Giovanna; Bhandari, Rashna; Chang, Christopher J.; Chen, Peng; Chen, Xing; Ciulli, Alessio; Cricco, Julia A.; Davis, Benjamin G.; Delbianco, Martina; Dudareva, Natalia; Dueber, Erin; Ferguson, Fleur; de Giuseppe, Priscila Oliveira; Hamachi, Itaru; Hammond, Ming Chen; Hatzios, Stavroula K.; Do Heo, Won; Janet, Jon Paul; Kamat, Siddhesh S.; Knapp, Stefan; Krishnan, Yamuna; Lang, Kathrin; Laraia, Luca; Leveson-Gower, Reuben B.; Li, Xiang David; Liu, David R.; Liu, Mo-Fang; London, Nir; Mahanta, Nilkamal; Mayor-Ruiz, Cristina; Muir, Tom; Murakami, Mario Tyago; Rhee, Hyun-Woo; Robers, Matt; Satz, Alex; Schulman, Brenda A.; Shen, Ben; Shoichet, Brian; Strauss, Erick; Suzuki, Tsutomu; Tiwary, Pratyush; Waldmann, Herbert; Ward, Thomas R.; Weeks, Amy; Weerapana, Eranthie; Winter, Georg Share Save
Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay Adariani, Soheila Rezaei; Agne, Daya; Koska, Sandra; Burhop, Annina; Seitz, Carina; Warmers, Jens; Janning, Petra; Metz, Malte; Pahl, Axel; Sievers, Sonja; Waldmann, Herbert; Ziegler, Slava Share Save
The Pseudo-Natural Product Tafbromin Selectively Targets the TAF1 Bromodomain 2 Patil, Sohan; Cremosnik, Gregor; Doetsch, Lara; Flegel, Jana; Schulte, Britta; Maier, Kerstin C.; Zumer, Kristina; Cramer, Patrick; Janning, Petra; Sievers, Sonja; Ziegler, Slava; Waldmann, Herbert Share Save
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Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP Cigler, Marko; Imrichova, Hana; Frommelt, Fabian; Caramelle, Lucie; Depta, Laura; Rukavina, Andrea; Kagiou, Chrysanthi; Hannich, J. Thomas; Mayor-Ruiz, Cristina; Superti-Furga, Giulio; Sievers, Sonja; Forrester, Alison; Laraia, Luca; Waldmann, Herbert; Winter, Georg E. Share Save
Illuminating Dark Chemical Matter Using the Cell Painting Assay Pahl, Axel; Liu, Jie; Patil, Sohan; Adariani, Soheila Rezaei; Scholermann, Beate; Warmers, Jens; Bonowski, Jana; Koska, Sandra; Akbulut, Yasemin; Seitz, Carina; Sievers, Sonja; Ziegler, Slava; Waldmann, Herbert Share Save
A chemical inhibitor of IST1-CHMP1B interaction impairs endosomal recycling and induces noncanonical LC3 lipidation Knyazeva, Anastasia; Li, Shuang; Corkery, Dale P.; Shankar, Kasturika; Herzog, Laura K.; Zhang, Xuepei; Singh, Birendra; Niggemeyer, Georg; Grill, David; Gilthorpe, Jonathan D.; Gaetani, Massimiliano; Carlson, Lars- Anders; Waldmann, Herbert; Wu, Yao-Wen Share Save
Discovery of a Novel Pseudo-Natural Product Aurora Kinase Inhibitor Chemotype through Morphological Profiling Wang, Lin; Yilmaz, Furkan; Yildirim, Okan; Schoelermann, Beate; Bag, Sukdev; Greiner, Luca; Pahl, Axel; Sievers, Sonja; Scheel, Rebecca; Strohmann, Carsten; Squire, Christopher; Foley, Daniel J.; Ziegler, Slava; Grigalunas, Michael; Waldmann, Herbert Share Save
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