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Andrew A. Pieper

case western reserve university

50H-index
222Paper Count
9.3KCitation Count
Published Papers 97
Publication Date
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Protein thiol alterations drive pathologic liquid–liquid phase separation in the aging brain
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2026-07-30
err0
errOAAI
errThibaut Vignane; Martín Hugo; Christian Hoffmann; Polina Reichert; Antonia Katsouda; Davide D’Andrea; Han Wang; Johannes V. Tromm; Marko Miler; Ferran Comas; Dunja Petrovic; Suyuan Chen; Jan Lj. Miljkovic; Danail Stoychev; Erik Lacko; Vladimir M. Jovanovic; Suwarna Chakraborty; Sunil J. Tripathi; Edwin Vázquez-Rosa; Jordan L. Morris; Suvagata Roy Chowdhury; Julien Prudent; Albert Sickmann; Natalija Polovic; Andrew A. Pieper; Ilan Davis; Kostas Tokatlidis; Bindu D. Paul; Michael P. Murphy; Christian Münch; Andreas Papapetropoulos; Dragomir Milovanovic; Milos R. Filipovic
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errSave
NPAS3-regulated astrocyte mitochondrial bioenergetics is required for cognition
errScience Advances
IF12.5
err2026-06-17
err0
errOAAI
errKateryna Murlanova; Ksenia Novototskaya-Vlasova; Shovgi Huseynov; Olga Pletnikova; Rebecca D. Howell; Yan Jouroukhin; Dong Won Kim; Adrian Eddy-Sulaiman Jenson; Juhyun Lee; Cheng Qin; Stephen R. Thompson; Vikyath Saraf; Michael J. Morales; Eduardo Cortes Gomez; Russell L. Margolis; Frederick C. Nucifora; Spencer R. Rosario; Andrew A. Pieper; Henry G. Withers; Samir Haj-Dahmane; Juhyun Kim; Mikhail V. Pletnikov
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errSave
15-PGDH inhibition enhances hematopoietic regeneration during aging
errStem Cells
IF3.6
err2025-10-01
err0
PREAI
errChaudhary, Rahul; Cordova, Brittany A.; Hong, Marcus; Klein, Bailey R.; Contreras, Lyannah A.; Rashmil, Ritisha; Goshevski, Filip; Smith, Julianne N. P.; Taylor, Derek J.; Pieper, Andrew A.; Markowitz, Sanford; Desai, Amar B.
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errSave
Real-world observations of GLP-1 receptor agonists and SGLT-2 inhibitors as potential treatments for Alzheimer's disease
errAlzheimer's & Dementia
IF11.1
err2025-09-02
err0
errOAAI
errPengyue Zhang; Chengsheng Mao; Anna Sun; Yuedi Yang; Yuan Hou; Zhimin Fu; Tousi Babak; James B. Leverenz; Andrew A. Pieper; Yuan Luo; Jeffrey Cummings; Feixiong Cheng
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errSave
Comprehensive characterization of the RNA editing landscape in the human aging brains with Alzheimer's disease
errAlzheimer's & Dementia
IF11.1
err2025-07-09
err0
errOAAI
errAmit Kumar Gupta; William Martin; Andrew A. Pieper; Yinsheng Wang; Andrew J. Saykin; Feixiong Cheng
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errSave
Astrocytic abnormalities in brain-specific Cacna1c-deficient mice: Implications for BBB impairment in neuropsychiatric diseases associated with CACNA1C mutations
errChannels
IF3.2
err2025-06-26
err0
errOAAI
errYeojung Koh; Maria Noterman-Soulinthavong; Anusha Bangalore; Uapingena P. Kandjoze; Zea Bud; Kamryn L. Noel; Hami Lee; Kathryn Franke; Coral J. Cintrón-Pérez; Anjali M. Rajadhyaksha; Eric B. Taylor; Andrew A. Pieper
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errSave
Cystic Fibrosis-related neurodegenerative disease associated with tauopathy and cognitive decline in aged CF mice
errJournal of Cystic Fibrosis
IF6
err2025-04-16
err0
errOAAI
errDanica F. Patton-Parfyonov; Xinming Wang; Sarah Barker; Deborah A. Corey; Edwin Vázquez-Rosa; Nichele Abeyesundere; Whitney M. Ward; Rebecca Darrah; Jung-A.A. Woo; David E. Kang; Andrew A. Pieper; Thomas J. Kelley
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errSave
Emerging approaches to bridging discovery science with clinical care in Alzheimer's disease
errNEUROTHERAPEUTICS
IF6.9
err2025-04-01
err0
errOAAI
errSinha, Subhash; Gan, Li; Pieper, Andrew A.
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errSave
Nrf2/Bach1 signaling axis: A promising multifaceted therapeutic strategy for Alzheimer's disease
errNEUROTHERAPEUTICS
IF6.9
err2025-04-01
err1
errOAAI
errSoni, Priyanka; Sharma, Sudarshana M.; Pieper, Andrew A.; Paul, Bindu D.; Thomas, Bobby
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errSave
Human herpesvirus-associated transposable element activation in human aging brains with Alzheimer's disease
errALZHEIMERS & DEMENTIA
IF11.1
err2025-02-22
err0
errOAAI
errFeng, YY; Cao, SQ; Shi, Y; Sun, AN; Flanagan, ME; Leverenz, JB; Pieper, AA; Jung, JU; Cummings, J; Fang, EF; Zhang, PY; Cheng, FX
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errSave
Utilization of precision medicine digital twins for drug discovery in Alzheimer's disease
errNEUROTHERAPEUTICS
IF6.9
err2025-02-01
err1
errOAAI
errRen, Yunxiao; Pieper, Andrew A.
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errSave
Single-microglia transcriptomic transition network-based prediction and real-world patient data validation identifies ketorolac as a repurposable drug for Alzheimer's disease
errALZHEIMERS & DEMENTIA
IF11.1
err2024-12-06
err0
PREAI
errXu, Jielin; Song, Wenqiang; Xu, Zhenxing; Danziger, Michael M.; Karavani, Ehud; Zang, Chengxi; Chen, Xin; Li, Yichen; Paz, Isabela M. Rivera; Gohel, Dhruv; Su, Chang; Zhou, Yadi; Hou, Yuan; Shimoni, Yishai; Pieper, Andrew A.; Hu, Jianying; Wang, Fei; Rosen-Zvi, Michal; Leverenz, James B.; Cummings, Jeffrey; Cheng, Feixiong
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errSave
Network medicine informed multiomics integration identifies drug targets and repurposable medicines for Amyotrophic Lateral Sclerosis
errNPJ SYSTEMS BIOLOGY AND APPLICATIONS
IF3.5
err2024-11-05
err0
errOAAI
errYu, Mucen; Xu, Jielin; Dutta, Ranjan; Trapp, Bruce; Pieper, Andrew A.; Cheng, Feixiong
errShare
errSave
Nanoparticle-based itaconate treatment recapitulates low-cholesterol/low-fat diet-induced atherosclerotic plaque resolution
errCELL REPORTS
IF6.9
err2024-11-01
err1
errOAAI
errHong, Natalie E.; Chaplin, Alice; Di, Lin; Ravodina, Anastasia; Bevan, Graham H.; Gao, Huiyun; Asase, Courteney; Gangwar, Roopesh Singh; Cameron, Mark J.; Mignery, Matthew; Cherepanova, Olga; Finn, Aloke V.; Nayak, Lalitha; Pieper, Andrew A.; Maiseyeu, Andrei
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errSave
Discovery of novel protective agents for infection-related delirium through bispectral electroencephalography
errTRANSLATIONAL PSYCHIATRY
IF6.2
err2024-10-03
err1
errOAAI
errNishiguchi, Tsuyoshi; Yamanishi, Kyosuke; Patel, Shivani; Malicoat, Johnny R.; Phuong, Nathan James; Seki, Tomoteru; Ishii, Takaya; Aoyama, Bun; Shimura, Akiyoshi; Gorantla, Nipun; Yamanashi, Takehiko; Iwata, Masaaki; Pieper, Andrew A.; Shinozaki, Gen
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errSave
Widespread transposable element dysregulation in human aging brains with Alzheimer's disease
errALZHEIMERS & DEMENTIA
IF11.1
err2024-10-02
err0
errOAAI
errFeng, Yayan; Yang, Xiaoyu; Hou, Yuan; Zhou, Yadi; Leverenz, James B.; Eng, Charis; Pieper, Andrew A.; Goate, Alison; Shen, Yin; Cheng, Feixiong
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errSave
Neuroprotective signaling by hydrogen sulfide and its dysregulation in Alzheimer's disease
errCURRENT OPINION IN CHEMICAL BIOLOGY
IF6.1
err2024-10-01
err2
errOAAI
errPaul, Bindu D.; Pieper, Andrew A.
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errSave
Acutely blocking excessive mitochondrial fission prevents chronic neurodegeneration after traumatic brain injury
errCELL REPORTS
IF6.9
err2024-09-01
err0
errOAAI
errSridharan, Preethy S.; Koh, Yeojung; Miller, Emiko; Hu, Di; Chakraborty, Suwarna; Tripathi, Sunil Jamuna; Kee, Teresa R.; Chaubey, Kalyani; Vazquez-Rosa, Edwin; Barker, Sarah; Liu, Hui; Leon-Alva, Rose A.; Frank, Kathryn; Cintron-Perez, Coral J.; Dhar, Matasha; Shin, Min-Kyoo; Flanagan, Margaret E.; Castellani, Rudolph J.; Gefen, Tamar; Bykova, Marina; Dou, Lijun; Cheng, Feixiong; Wilson, Brigid M.; Fujioka, Hisashi; Kang, David E.; Woo, Jung-A. A.; Paul, Bindu D.; Qi, Xin; Pieper, Andrew A.
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errSave
Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injury
errMOLECULAR NEURODEGENERATION
IF17.5
err2024-06-24
err2
errOAAI
errBravo, Celeste Parra; Krukowski, Karen; Barker, Sarah; Wang, Chao; Li, Yaqiao; Fan, Li; Vazquez-Rosa, Edwin; Shin, Min-Kyoo; Wong, Man Ying; McCullough, Louise D.; Kitagawa, Ryan S.; Choi, H. Alex; Cacace, Angela; Sinha, Subhash C.; Pieper, Andrew A.; Rosi, Susanna; Chen, Xu; Gan, Li
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errSave
Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer's disease
errCELL REPORTS
IF6.9
err2024-05-01
err3
errOAAI
errQiu, Yunguang; Hou, Yuan; Gohel, Dhruv; Zhou, Yadi; Xu, Jielin; Bykova, Marina; Yang, Yuxin; Leverenz, James B.; Pieper, Andrew A.; Nussinov, Ruth; Caldwell, Jessica Z. K.; Brown, J. Mark; Cheng, Feixiong
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Solomon H. Snyder
H-index: 222 · Papers: 1.2K
J
Jeffrey L. Cummings
H-index: 176 · Papers: 1.5K
J
Jay Shendure
H-index: 167 · Papers: 662
A
Alison Goate
H-index: 155 · Papers: 1.2K
A
Andrew J. Saykin
H-index: 154 · Papers: 1.9K
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