Paul H. Weinreb - Publications, H-index & Citations

Back

Paul H. Weinreb

Biogen

52H-index

148Paper Count

1.3WCitation Count

Published Papers 60

Publication Date

Balancing brain exposure, pharmacokinetics and safety of transferrin receptor antibodies for delivery of neuro-therapeutics

MABS

IF7.3

2025-12-31

PREAI

Smith, Benjamin A.; Meeks, Caitlin B.; Murray-Brown, Isabel; McCarthy, Elizabeth A.; Julian, Mark C.; Arndt, Joe; Stewart, Matthew; Spilker, Kerri; D'Lima, Nadia; Dolnikova, Jana; Li, You; Prasad, Shikha; Qian, Fang; Gong, Bangjian; Jiang, Di; Yuan, Long; Tuczkewycz, Taras; Amatucci, Joseph; Doyle, Rachel; Wagatsuma, Akiko; Yang, Fu-Chia; Pepinsky, Blake; Weinreb, Paul H.; Cameron, Thomas O.; Koksal, Adem C.

Save

Transferrin receptor–targeted anti-amyloid antibody enhances brain delivery and mitigates ARIA

Science

IF45.8

2025-08-07

PREAI

Michelle E. Pizzo; Edward D. Plowey; Nathalie Khoury; Wanda Kwan; Jordan Abettan; Sarah L. DeVos; Claire B. Discenza; Timothy Earr; David Joy; Ming Lye-Barthel; Elysia Roche; Darren Chan; Jason C. Dugas; Kapil Gadkar; Stefan Hamann; René Meisner; Jennifer Sebalusky; Ana Claudia Silva Amaral; Isabel Becerra; Roni Chau; Johann Chow; Allisa J. Clemens; Mark S. Dennis; Joseph Duque; Laura Fusaro; Jennifer A. Getz; Mihalis S. Kariolis; Do Jin Kim; Kendra J. Lechtenberg; Amy Wing-Sze Leung; Arash Moshkforoush; Hoang N. Nguyen; Emmanuel S. Ojo; Elliot R. Thomsen; Vanessa O. Torres; Pascal E. Sanchez; Lu Shan; Adam P. Silverman; Zachary K. Sweeney; Hilda Solanoy; Raymond Tong; Meredith E. Calvert; Ryan J. Watts; Robert G. Thorne; Paul H. Weinreb; Dominic M. Walsh; Joseph W. Lewcock; Thierry Bussiere; Y. Joy Yu Zuchero

Save

Comparative assessment of binding and functional differences of clinical antibodies targeting α-synuclein in cellular models of Parkinson’s disease

Biomedicine & Pharmacotherapy

IF7.5

2025-06-18

PREAI

YuTing Liu; Isin Dalkilic-Liddle; You Li; Benjamin A. Smith; Thomas O. Cameron; Joseph W. Arndt; Chao Quan; Andreas Lehmann; Daniel J. Apicco; Lori Hrdlicka; Andreas Weihofen; Warren D. Hirst; Edward D. Plowey; Paul H. Weinreb; Blake Pepinsky

Save

Quantification of cinpanemab (BIIB054) binding to α-synuclein in cerebrospinal fluid of phase 1 single ascending dose samples

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2025-01-01

PREAI

Liu, Yuting; Yang, Minhua; Fraser, Kyle; Graham, Danielle; Weinreb, Paul H.; Weihofen, Andreas; Hirst, Warren D.; Cedarbaum, Jesse M.; Pepinsky, Blake

Save

Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin β6

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

153

OAAI

Azare, Janeen; Leslie, Kenneth; Al-Ahmadie, Hikmat; Gerald, William; Weinreb, Paul H.; Violette, Shelia M.; Bromberg, Jacqueline

Save

Characterization of tau binding by gosuranemab

NEUROBIOLOGY OF DISEASE

IF5.6

2020-12-01

OAAI

Sopko, Richelle; Golonzhka, Olga; Arndt, Joseph; Quan, Chao; Czerkowicz, Julie; Cameron, Andrew; Smith, Benjamin; Murugesan, Yogapriya; Gibbons, Garrett; Kim, Soo-Jung; Trojanowski, John Q.; Lee, Virginia M. Y.; Brunden, Kurt R.; Graham, Danielle L.; Weinreb, Paul H.; Hering, Heike

Save

Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2020-09-28

132

PREAI

Linse, Sara; Scheidt, Tom; Bernfur, Katja; Vendruscolo, Michele; Dobson, Christopher M.; Cohen, Samuel I. A.; Sileikis, Eimantas; Lundqvist, Martin; Qian, Fang; O'Malley, Tiernan; Bussiere, Thierry; Weinreb, Paul H.; Xu, Catherine K.; Meisl, Georg; Devenish, Sean R. A.; Knowles, Tuomas P. J.; Hansson, Oskar

Save

The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis

JOURNAL OF EXTRACELLULAR VESICLES

IF14.5

2020-05-20

OAAI

Krishn, Shiv Ram; Salem, Israa; Quaglia, Fabio; Naranjo, Nicole M.; Agarwal, Ekta; Liu, Qin; Sarker, Srawasti; Kopenhaver, Jessica; McCue, Peter A.; Weinreb, Paul H.; Violette, Shelia M.; Altieri, Dario C.; Languino, Lucia R.

Save

Aggregated SOD1 causes selective death of cultured human motor neurons

SCIENTIFIC REPORTS

IF3.9

2018-11-06

OAAI

Benkler, Chen; O'Neil, Alison L.; Slepian, Susannah; Qian, Fang; Weinreb, Paul H.; Rubin, Lee L.

Save

Inhibition of integrin αVβ6 changes fibril thickness of stromal collagen in experimental carcinomas

CELL COMMUNICATION AND SIGNALING

IF8.9

2018-07-02

OAAI

Olsson, P. Olof; Gustafsson, Renata; Salnikov, Alexei, V; Gothe, Maria; Zeller, Kathrin S.; Friman, Tomas; Baldetorp, Bo; Koopman, Louise A.; Weinreb, Paul H.; Violette, Shelia M.; Kalamajski, Sebastian; Heldins, Nils-Erik; Rubin, Kristofer

Save

Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-β

SCIENTIFIC REPORTS

IF3.9

2018-04-23

231

OAAI

Arndt, Joseph W.; Qian, Fang; Smith, Benjamin A.; Quan, Chao; Kilambi, Krishna Praneeth; Bush, Martin W.; Walz, Thomas; Pepinsky, R. Blake; Bussiere, Thierry; Hamann, Stefan; Cameron, Thomas O.; Weinreb, Paul H.

Save

Monoclonal antibody exposure in rat and cynomolgus monkey cerebrospinal fluid following systemic administration

FLUIDS AND BARRIERS OF THE CNS

IF6.2

2018-03-20

OAAI

Wang, Qin; Delva, Luisette; Weinreb, Paul H.; Pepinsky, Robert B.; Graham, Danielle; Veizaj, Elvana; Cheung, Anne E.; Chen, Weiping; Nestorov, Ivan; Rohde, Ellen; Caputo, Robin; Kuesters, Geoffrey M.; Bohnert, Tonika; Gan, Liang-Shang

Save

Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis

JCI INSIGHT

IF6.1

2017-05-04

OAAI

Shea, Barry S.; Probst, Clemens K.; Brazee, Patricia L.; Rotile, Nicholas J.; Blasi, Francesco; Weinreb, Paul H.; Black, Katharine E.; Sosnovik, David E.; Van Cott, Elizabeth M.; Violette, Shelia M.; Caravan, Peter; Tager, Andrew M.

Save

Type I collagen-targeted PET probe for pulmonary fibrosis detection and staging in preclinical models

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2017-04-05

126

OAAI

Desogere, Pauline; Tapias, Luis F.; Hariri, Lida P.; Rotile, Nicholas J.; Rietz, Tyson A.; Probst, Clemens K.; Blasi, Francesco; Day, Helen; Mino-Kenudson, Mari; Weinreb, Paul; Violette, Shelia M.; Fuchs, Bryan C.; Tager, Andrew M.; Lanuti, Michael; Caravan, Peter

Save

Fibronectin-guided migration of carcinoma collectives

NATURE COMMUNICATIONS

IF15.7

2017-01-19

156

OAAI

Gopal, Sandeep; Veracini, Laurence; Grall, Dominique; Butori, Catherine; Schaub, Sebastien; Audebert, Stephane; Camoin, Luc; Baudelet, Emilie; Radwanska, Agata; Divonne, Stephanie Beghelli-de la Forest; Violette, Shelia M.; Weinreb, Paul H.; Rekima, Samah; Ilie, Marius; Sudaka, Anne; Hofman, Paul; Van Obberghen-Schilling, Ellen

Save

Inhibition of αvβ5 Integrin Attenuates Vascular Permeability and Protects against Renal Ischemia-Reperfusion Injury

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

IF9.4

2017-01-06

OAAI

McCurley, Amy; Alimperti, Stella; Campos-Bilderback, Silvia B.; Sandoval, Ruben M.; Calvino, Jenna E.; Reynolds, Taylor L.; Quigley, Catherine; Mugford, Joshua W.; Polacheck, William J.; Gomez, Ivan G.; Dovey, Jennifer; Marsh, Graham; Huang, Angela; Qian, Fang; Weinreb, Paul H.; Dolinski, Brian M.; Moore, Shaun; Duffield, Jeremy S.; Chen, Christopher S.; Molitoris, Bruce A.; Violette, Shelia M.; Crackower, Michael A.

Save

αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor

CANCER RESEARCH

IF16.6

2016-08-31

OAAI

Lu, Huimin; Wang, Tao; Li, Jing; Fedele, Carmine; Liu, Qin; Zhang, Jianzhong; Jiang, Zhong; Jain, Dhanpat; Iozzo, Renato V.; Violette, Shelia M.; Weinreb, Paul H.; Davis, Roger J.; Gioeli, Daniel; FitzGerald, Thomas J.; Altieri, Dario C.; Languino, Lucia R.

Save

Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-04-01

OAAI

Tatler, Amanda L.; Habgood, Anthony; Porte, Joanne; John, Alison E.; Stavrou, Anastasios; Hodge, Emily; Kerama-Likoko, Cheryl; Violette, Shelia M.; Weinreb, Paul H.; Knox, Alan J.; Laurent, Geoffrey; Parfrey, Helen; Wolters, Paul John; Wallace, William; Alberti, Siegfried; Nordheim, Alfred; Jenkins, Gisli

Save

Integrin αvβ6 critically regulates hepatic progenitor cell function and promotes ductular reaction, fibrosis, and tumorigenesis

HEPATOLOGY

IF15.8

2015-11-23

OAAI

Peng, Zhen-Wei; Ikenaga, Naoki; Liu, Susan B.; Sverdlov, Deanna Y.; Vaid, Kahini A.; Dixit, Richa; Weinreb, Paul H.; Violette, Shelia; Sheppard, Dean; Schuppan, Detlef; Popov, Yury

Save

Generalized Faddeev-Popov method for a deformed supersymmetric Yang-Mills theory

PHYSICS LETTERS B

IF4.5

2015-09-01

OAAI

Weinreb, Paul; Faizal, Mir

Save

Research Directions