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DNA replication stress underpins the vulnerability to oxidative phosphorylation inhibition in colorectal cancer Zhao, Xiao Hong; Han, Man Man; Yan, Qian Qian; Yue, Yi Meng; Ye, Kaihong; Zhang, Yuan Yuan; Teng, Liu; Xu, Liang; Shi, Xiao-Jing; La, Ting; Feng, Yu Chen; Xu, Ran; Narayana, Vinod K.; De Souza, David P.; Quek, Lake-Ee; Holst, Jeff; Liu, Tao; Baker, Mark A.; Thorne, Rick F.; Zhang, Xu Dong; Jin, Lei Share Save
Macropinocytosis mediates resistance to loss of glutamine transport in triple-negative breast cancer Wahi, Kanu; Freidman, Natasha; Wang, Qian; Devadason, Michelle; Quek, Lake-Ee; Pang, Angel; Lloyd, Larissa; Larance, Mark; Zanini, Fabio; Harvey, Kate; O'Toole, Sandra; Guan, Yi Fang; Holst, Jeff Share Save
ACSM1 and ACSM3 Regulate Fatty Acid Metabolism to Support Prostate Cancer Growth and Constrain Ferroptosis Shrestha, Raj K.; Nassar, Zeyad D.; Hanson, Adrienne R.; Iggo, Richard; Townley, Scott L.; Dehairs, Jonas; Mah, Chui Y.; Helm, Madison; Alizadeh-Ghodsi, Mohammadreza; Pickering, Marie; Ghesquiere, Bart; Watt, Matthew J.; Quek, Lake-Ee; Hoy, Andrew J.; Tilley, Wayne D.; Swinnen, Johannes V.; Butler, Lisa M.; Selth, Luke A. Share Save
Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism Filipe, Elysse C.; Velayuthar, Sipiththa; Philp, Ashleigh; Nobis, Max; Latham, Sharissa L.; Parker, Amelia L.; Murphy, Kendelle J.; Wyllie, Kaitlin; Major, Gretel S.; Contreras, Osvaldo; Mok, Ellie T. Y.; Enriquez, Ronaldo F.; Mcgowan, Suzanne; Feher, Kristen; Quek, Lake-Ee; Hancock, Sarah E.; Yam, Michelle; Tran, Emmi; Setargew, Yordanos F. I.; Skhinas, Joanna N.; Chitty, Jessica L.; Phimmachanh, Monica; Han, Jeremy Z. R.; Cadell, Antonia L.; Papanicolaou, Michael; Mahmodi, Hadi; Kiedik, Beata; Junankar, Simon; Ross, Samuel E.; Lam, Natasha; Coulson, Rhiannon; Yang, Jessica; Zaratzian, Anaiis; Da Silva, Andrew M.; Tayao, Michael; Chin, Ian L.; Cazet, Aurelie; Kansara, Maya; Segara, Davendra; Parker, Andrew; Hoy, Andrew J.; Harvey, Richard P.; Bogdanovic, Ozren; Timpson, Paul; Croucher, David R.; Lim, Elgene; Swarbrick, Alexander; Holst, Jeff; Turner, Nigel; Choi, Yu Suk; Kabakova, Irina V.; Philp, Andrew; Cox, Thomas R. Share Save
Peroxisomal β-oxidation enzyme, DECR2, regulates lipid metabolism and promotes treatment resistance in advanced prostate cancer Mah, Chui Yan; Nguyen, An Dieu Trang; Niijima, Takuto; Helm, Madison; Dehairs, Jonas; Ryan, Feargal J.; Ryan, Natalie; Quek, Lake-Ee; Hoy, Andrew J.; Don, Anthony S.; Mills, Ian G.; Swinnen, Johannes V.; Lynn, David J.; Nassar, Zeyad D.; Butler, Lisa M. Share Save
Host-microbiome interactions in nicotinamide mononucleotide (NMN) deamidation Kim, Lynn-Jee; Chalmers, Timothy J. J.; Madawala, Romanthi; Smith, Greg C. C.; Li, Catherine; Das, Abhirup; Poon, Eric Wing Keung; Wang, Jun; Tucker, Simon P. P.; Sinclair, David A. A.; Quek, Lake-Ee; Wu, Lindsay E. E. Share Save
Disruption of nucleotide homeostasis confers cancer cell susceptibility to oxidative phosphorylation inhibition independently of energy depletion Zhao, Xiaohong; Zhang, Yuan Yuan; Xu, Liang; La, Ting; Feng, Yu Chen; Tang, Hai Jie; Xu, Ran; Narayana, Vinod K.; De Souza, David P.; Quek, Lake-Ee; Holst, Jeff; Thorne, Rick F.; Baker, Mark; Liu, Tao; Jin, Lei; Zhang, Xu Dong Share Save
Insulin sensitivity is preserved in mice made obese by feeding a high starch diet Brandon, Amanda E.; Small, Lewin; Nguyen, Tuong-Vi; Suryana, Eurwin; Gong, Henry; Yassmin, Christian; Hancock, Sarah E.; Pulpitel, Tamara; Stonehouse, Sophie; Prescott, Letisha; Kebede, Melkam A.; Yau, Belinda; Quek, Lake-Ee; Kowalski, Greg M.; Bruce, Clinton R.; Turner, Nigel; Cooney, Gregory J. Share Save
Glutamine addiction promotes glucose oxidation in triple-negative breast cancer Quek, Lake-Ee; van Geldermalsen, Michelle; Guan, Yi Fang; Wahi, Kanu; Mayoh, Chelsea; Balaban, Seher; Pang, Angel; Wang, Qian; Cowley, Mark J.; Brown, Kristin K.; Turner, Nigel; Hoy, Andrew J.; Holst, Jeff Share Save
A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth Gillis, Joanna L.; Hinneh, Josephine A.; Ryan, Natalie K.; Irani, Swati; Moldovan, Max; Quek, Lake-Ee; Shrestha, Raj K.; Hanson, Adrienne R.; Xie, Jianling; Hoy, Andrew J.; Holst, Jeff; Centenera, Margaret M.; Mills, Ian G.; Lynn, David J.; Selth, Luke A.; Butler, Lisa M. Share Save
Gut-derived acetate promotes B10 cells with antiinflammatory effects Daien, C., I; Tan, J.; Audo, R.; Mielle, J.; Quek, L. E.; Krycer, J. R.; Angelatos, A.; Duraes, M.; Pinget, G.; Ni, D.; Robert, R.; Alam, M. J.; Amian, M. C. B.; Sierro, F.; Parmar, A.; Perkins, G.; Hoque, S.; Gosby, A. K.; Simpson, S. J.; Ribeiro, R., V; Mackay, C. R.; Macia, L. Share Save
Insulin signaling requires glucose to promote lipid anabolism in adipocytes Krycer, James R.; Quek, Lake-Ee; Francis, Deanne; Zadoorian, Armella; Weiss, Fiona C.; Cooke, Kristen C.; Nelson, Marin E.; Diaz-Vegas, Alexis; Humphrey, Sean J.; Scalzo, Richard; Hirayama, Akiyoshi; Ikeda, Satsuki; Shoji, Futaba; Suzuki, Kumi; Huynh, Kevin; Giles, Corey; Varney, Bianca; Nagarajan, Shilpa R.; Hoy, Andrew J.; Soga, Tomoyoshi; Meikle, Peter J.; Cooney, Gregory J.; Fazakerley, Daniel J.; James, David E. Share Save
Vulnerabilities in glutamine metabolism define triple-negative from Luminal A breast cancer subsets van Geldermalsen, Michelle; Quek, Lake-Ee; Turner, Nigel; Balaban, Seher; Hoy, Andrew; Pang, Angel; Guan, Yi Fang; Wahi, Kanu; Wang, Qian; Holst, Jeff Share Save
Lactate production is a prioritized feature of adipocyte metabolism Krycer, James R.; Quek, Lake-Ee; Francis, Deanne; Fazakerley, Daniel J.; Elkington, Sarah D.; Diaz-Vegas, Alexis; Cooke, Kristen C.; Weiss, Fiona C.; Duan, Xiaowen; Kurdyukov, Sergey; Zhou, Ping-Xin; Tambar, Uttam K.; Hirayama, Akiyoshi; Ikeda, Satsuki; Kamei, Yushi; Soga, Tomoyoshi; Cooney, Gregory J.; James, David E. Share Save
Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress Byrne, Frances L.; Olzomer, Ellen M.; Marriott, Gabriella R.; Quek, Lake-Ee; Katen, Alice; Su, Jacky; Nelson, Marin E.; Hart-Smith, Gene; Larance, Mark; Sebesfi, Veronica F.; Cuff, Jeff; Martyn, Gabriella E.; Childress, Elizabeth; Alexopoulos, Stephanie J.; Poon, Ivan K.; Faux, Maree C.; Burgess, Antony W.; Reid, Glen; McCarroll, Joshua A.; Santos, Webster L.; Quinlan, Kate G. R.; Turner, Nigel; Fazakerley, Daniel J.; Kumar, Naresh; Hoehn, Kyle L. Share Save
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