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Modulation of infiltrating CD206+macrophages restricts progression of pulmonary lymphangioleiomyomatosis Liu, Heng-Jia; Diesler, Remi; Chami, Joelle; Wu, Boxiang; Du, Heng; Jin, Yue; Daou, Melissa; Alesi, Nicola; Khabibullin, Damir; Leroux, Caroline; Cottin, Vincent; Cantley, Lloyd G.; Rudloff, Udo; Henske, Elizabeth P. Share Save
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Fatty Acid Derivatization and Cyclization of the Immunomodulatory Peptide RP-182 Targeting CD206high Macrophages Improve Antitumor Activity Singh, Sitanshu S.; Calvo, Raul; Kumari, Anju; Sable, Rushikesh V.; Fang, Yuhong; Tao, Dingyin; Hu, Xin; Castle, Sarah Gray; Nahar, Saifun; Li, Dandan; Major, Emily; Sanchez, Tino W.; Kato, Rintaro; Xu, Xin; Zhou, Jian; Liu, Liang; Leclair, Christopher A.; Simeonov, Anton; Baljinnyam, Bolormaa; Henderson, Mark J.; Marugan, Juan; Rudloff, Udo Share Save
A Novel CD206 Targeting Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice Ghebremedhin, Anghesom; Bin Salam, Ahmad; Adu-Addai, Benjamin; Noonan, Steve; Stratton, Richard; Ahmed, Md Shakir Uddin; Khantwal, Chandra; Martin, George R.; Lin, Huixian; Andrews, Chris; Karanam, Balasubramanyam; Rudloff, Udo; Lopez, Henry; Jaynes, Jesse; Yates, Clayton Share Save
Scaffolding Protein Connector Enhancer of Kinase Suppressor of Ras 1 (CNKSR1) Regulates MAPK Inhibition Responsiveness in Pancreas Cancer via Crosstalk with AKT Signaling Li, Dandan; Miermont, Anne M.; Sable, Rushikesh; Quadri, Humair S.; Griner, Lesley A. Mathews; Martin, Scott E.; Odzorig, Taivan; De, Soumita; Ferrer, Marc; Powers, Astin S.; Hewitt, Stephen M.; Rudloff, Udo Share Save
Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis Frankowski, Kevin J.; Patnaik, Samarjit; Wang, Chen; Southall, Noel; Dutta, Dipannita; De, Soumitta; Li, Dandan; Dextras, Christopher; Lin, Yi-Han; Bryant-Connah, Marthe; Davis, Danielle; Wang, Feijun; Wachsmuth, Leah M.; Shah, Pranav; Williams, Jordan; Kabir, Md; Zhu, Edward; Baljinnyam, Bolormaa; Wang, Amy; Xu, Xin; Norton, John; Ferrer, Marc; Titus, Steve; Simeonov, Anton; Zheng, Wei; Griner, Lesley A. Mathews; Jadhav, Ajit; Aube, Jeffrey; Henderson, Mark J.; Rudloff, Udo; Schoenen, Frank J.; Huang, Sui; Marugan, Juan J. Share Save
T Cell-Mediated Antitumor Immunity Cooperatively Induced By TGFβR1 Antagonism and Gemcitabine Counteracts Reformation of the Stromal Barrier in Pancreatic Cancer Li, Dandan; Schaub, Nicholas; Guerin, Theresa M.; Bapiro, Tashinga E.; Richards, Frances M.; Chen, Vicky; Talsania, Keyur; Kumar, Parimal; Gilbert, Debra J.; Schlomer, Jerome J.; Kim, Seong-Jin; Sorber, Rebecca; Teper, Yaroslav; Bautista, Wendy; Palena, Claudia; Ock, Chan-Young; Jodrell, Duncan, I; Pate, Nathan; Mehta, Monika; Zhao, Yongmei; Kozlov, Serguei; Rudloff, Udo Share Save
Phase II study of selumetinib, an orally active inhibitor of MEK1 and MEK2 kinases, in KRASG12R-mutant pancreatic ductal adenocarcinoma Kenney, Cara; Kunst, Tricia; Webb, Santhana; Christina, Devisser, Jr.; Arrowood, Christy; Steinberg, Seth M.; Mettu, Niharika B.; Kim, Edward J.; Rudloff, Udo Share Save
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LC-MS/MS assay coupled with carboxylic acid magnetic bead affinity capture to quantitatively measure cationic host defense peptides (HDPs) in complex matrices with application to preclinical pharmacokinetic studies O'Neill, Maura J.; Chan, King; Jaynes, Jesse M.; Knotts, Zachary; Xu, Xia; Abisoye-Ogunniyan, Abisola; Guerin, Theresa; Schlomer, Jerome; Li, Dandan; Cary, Jeffrey W.; Rajasekaran, Kanniah; Yates, Clayton; Kozlov, Serguei; Andresson, Thorkell; Rudloff, Udo Share Save
Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses Jaynes, Jesse M.; Sable, Rushikesh; Ronzetti, Michael; Bautista, Wendy; Knotts, Zachary; Abisoye-Ogunniyan, Abisola; Li, Dandan; Calvo, Raul; Dashnyam, Myagmarjav; Singh, Anju; Guerin, Theresa; White, Jason; Ravichandran, Sarangan; Kumar, Parimal; Talsania, Keyur; Chen, Vicky; Ghebremedhin, Anghesom; Karanam, Balasubramanyam; Bin Salam, Ahmad; Amin, Ruksana; Odzorig, Taivan; Aiken, Taylor; Nguyen, Victoria; Bian, Yansong; Zarif, Jelani C.; de Groot, Amber E.; Mehta, Monika; Fan, Lixin; Hu, Xin; Simeonov, Anton; Pate, Nathan; Abu-Asab, Mones; Ferrer, Marc; Southall, Noel; Ock, Chan-Young; Zhao, Yongmei; Lopez, Henry; Kozlov, Serguei; de Val, Natalia; Yates, Clayton C.; Baljinnyam, Bolormaa; Marugan, Juan; Rudloff, Udo Share Save
Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer Hobbs, G. Aaron; Baker, Nicole M.; Miermont, Anne M.; Thurman, Ryan D.; Pierobon, Mariaelena; Tran, Timothy H.; Anderson, Andrew O.; Waters, Andrew M.; Diehl, J. Nathaniel; Papke, Bjoern; Hodge, Richard G.; Klomp, Jennifer E.; Goodwin, Craig M.; DeLiberty, Jonathan M.; Wang, Junning; Ng, Raymond W. S.; Gautam, Prson; Bryant, Kirsten L.; Esposito, Dominic; Campbell, Sharon L.; Petricoin, Emanuel F., III; Simanshu, Dhirendra K.; Aguirre, Andrew J.; Wolpin, Brian M.; Wennerberg, Krister; Rudloff, Udo; Cox, Adrienne D.; Der, Channing J. Share Save
Precision targeting of M2-like macrophages by the innate defense regulator RP-182 in pancreatic cancer and noncancerous diseases Sable, Rushikesh; Jaynes, Jesse; Ronzetti, Michael; Guzman, Wendy; Knotts, Zachary; de Val, Natalia; Morgan, Juan; Yates, Clayton; Bolormaa, Baljinnyam; Rudloff, Udo Share Save
Target Deconvolution of a Multikinase Inhibitor with Antimetastatic Properties Identifies TAOK3 as a Key Contributor to a Cancer Stem Cell-Like Phenotype Bian, Yansong; Teper, Yaroslav; Griner, Lesley A. Mathews; Aiken, Taylor J.; Shukla, Vivek; Guha, Rajarshi; Shinn, Paul; Xin, Hong-Wu; Pflicke, Holger; Powers, Astin S.; Li, Dandan; Jiang, Jian-kang; Patel, Paresma; Rogers, Steven A.; Aube, Jeffrey; Ferrer, Marc; Thomas, Craig J.; Rudloff, Udo Share Save
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Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis Frankowski, Kevin J.; Wang, Chen; Patnaik, Samarjit; Schoenen, Frank J.; Southall, Noel; Li, Dandan; Teper, Yaroslav; Sun, Wei; Kandela, Irawati; Hu, Deqing; Dextras, Christopher; Knotts, Zachary; Bian, Yansong; Norton, John; Titus, Steve; Lewandowska, Marzena A.; Wen, Yiping; Farley, Katherine I.; Griner, Lesley Mathews; Sultan, Jamey; Meng, Zhaojing; Zhou, Ming; Vilimas, Tomas; Powers, Astin S.; Kozlov, Serguei; Nagashima, Kunio; Quadri, Humair S.; Fang, Min; Long, Charles; Khanolkar, Ojus; Chen, Warren; Kang, Jinsol; Huang, Helen; Chow, Eric; Goldberg, Esthermanya; Feldman, Coral; Xi, Romi; Kim, Hye Rim; Sahagian, Gary; Baserga, Susan J.; Mazar, Andrew; Ferrer, Marc; Zheng, Wei; Shilatifard, Ali; Aube, Jeffrey; Rudloff, Udo; Marugan, Juan Jose; Huang, Sui Share Save
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The Changing Paradigm of Management of Liver Abscesses in Chronic Granulomatous Disease Straughan, David M.; McLoughlin, Kaitlin C.; Mullinax, John E.; Marciano, Beatriz E.; Freeman, Alexandra F.; Anderson, Victoria L.; Uzel, Gulbu; Azoury, Said C.; Sorber, Rebecca; Quadri, Humair S.; Malech, Harry L.; DeRavin, Suk See; Kamal, Natasha; Koh, Christopher; Zerbe, Christa S.; Kuhns, Douglas B.; Gallin, John I.; Heller, Theo; Holland, Steven M.; Rudloff, Udo Share Save
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