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James Inglese

National Center for Advancing Translational Sciences

69H-index
345Paper Count
2.0WCitation Count
Published Papers 95
Publication Date
Uncovering the isoform-resolution kinetic landscape of nonsense-mediated mRNA decay with EZbakR
err2026-07-15
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errJustin W. Mabin; Isaac W. Vock; Martin Machyna; Nazmul Haque; Poonam Thakran; Alexandra Zhang; Ganesha Rai; Isabelle Nathalie-Marie Leibler; James Inglese; Matthew D. Simon; J. Robert Hogg
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A fission yeast-based platform for nematode PDE inhibitor discovery
err2026-03-01
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errBibeau, Sarah; Chen, Natalie; Sutoris, Hannah; Ly, Judy; Eberhard, Jeremy; Hubbell, Sara M.; Banda, Eric; Povh, Esther; Anindya, Clianta S.; Berwanger, Michael R.; Sinise, Sarah E.; Zhang, Xieyang; Morken, James P.; Galande, Kranti K.; Cote, Rick H.; Dranchak, Patricia K.; Inglese, James; Hoffman, Charles S.
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Metabolic engineering and late-stage functionalization expand the chemical space of the antimalarial premarineosin A
err2025-12-05
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errChristina M. McBride; Morgan McCauley; Natalia R. Harris; Sahar Amin; Brian J. Curtis; Linnea Verhey-Henke; Awet A. Teklemichael; Erin N. Oliphant; Patricia Dranchak; Katherine L. Lev; Fengrui Qu; Harrison M. Snodgrass; Jared C. Lewis; James Inglese; Xin-Zhuan Su; Filipa Pereira; David H. Sherman
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A general assay platform to study protein pharmacology using ligand-dependent structural dynamics
err2025-05-10
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errCiulla, Daniel A.; Dranchak, Patricia K.; Aitha, Mahesh; van Neer, Renier H. P.; Shah, Divia; Tharakan, Ravi; Wilson, Kelli M.; Wang, Yuhong; Braisted, John C.; Inglese, James
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Neuroprotection in C. Elegans Models of Parkinson's Disease: Discovering Therapeutics Via Small Molecule and RNA Interference
err2025-03-01
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PREAI
errMartinez, Miguel a.; Akano, Emmanuel o.; Surtel, Alexis a.; Dranchak, Patricia k.; Ash, Carl t.; Anderson, Emily e.; Moritz, Amy; Free, R. benjamin; Steiner, Joseph p.; Inglese, James; Sibley, David r.
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Active- and Allosteric-Site Cyclic Peptide Inhibitors of Secreted M. tuberculosis Chorismate Mutase
err2025-02-04
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PREAI
errvan Neer, Renier H. P.; Dranchak, Patricia K.; Aitha, Mahesh; Liu, Lijun; Carlson, Emma K.; Jacobsen, Isabella E.; Battaile, Kevin; Fang, Yuhong; Tao, Dingyin; Rai, Ganesha; Padia, Janak; Lovell, Scott; Suga, Hiroaki; Inglese, James
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Differential Mobility Spectrometry Acoustic Ejection Mass Spectrometer System for Screening Isomerization-Mediating Enzyme Drug Targets
err2024-12-19
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PREAI
errBazargan, Samad; Dranchak, Patricia; Liu, Chang; Inglese, James; Janiszewski, John; Schneider, Bradley B.; Covey, Thomas R.
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Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase
err2024-05-10
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errCheng, Zishuo; Aitha, Mahesh; Thomas, Caitlyn A.; Sturgill, Aidan; Fairweather, Mitch; Hu, Amy; Bethel, Christopher R.; Rivera, Dann D.; Dranchak, Patricia; Thomas, Pei W.; Li, Han; Feng, Qi; Tao, Kaicheng; Song, Minshuai; Sun, Na; Wang, Shuo; Silwal, Surendra Bikram; Page, Richard C.; Fast, Walt; Bonomo, Robert A.; Weese, Maria; Martinez, Waldyn; Inglese, James; Crowder, Michael W.
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Methotrexate-based PROTACs as DHFR-specific chemical probes
err2024-02-01
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errRana, Sandeep; Dranchak, Patricia; Dahlin, Jayme L.; Lamy, Laurence; Li, Wenqing; Oliphant, Erin; Shrimp, Jonathan H.; Rajacharya, Girish H.; Tharakan, Ravi; Holland, David O.; Whitten, Apryl S.; Wilson, Kelli M.; Singh, Pankaj K.; Durum, Scott K.; Tao, Dingyin; Rai, Ganesha; Inglese, James
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Identification of Small Molecule Therapeutics and Neuroprotective Gene Targets via High Throughput Screening and RNA Interference in C. elegans Parkinson's Disease Models
err2023-06-01
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errAsh, Carl T.; Anderson, Emily E.; Moritz, Amy E.; Dranchak, Patricia K.; Free, R. Benjamin; Inglese, James; Steiner, Joseph P.; Sibley, David R.; Akano, Emmanuel O.
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In vivo quantitative high-throughput screening for drug discovery and comparative toxicology
err2023-03-20
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errDranchak, Patricia K.; Oliphant, Erin; Queme, Bryan; Lamy, Laurence; Wang, Yuhong; Huang, Ruili; Xia, Menghang; Tao, Dingyin; Inglese, James
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A cell-based bioluminescence reporter assay of human Sonic Hedgehog protein autoprocessing to identify inhibitors and activators
err2022-12-01
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errCiulla, Daniel A.; Dranchak, Patricia; Pezzullo, John L.; Mancusi, Rebecca A.; Psaras, Alexandra Maria; Rai, Ganesha; Giner, Jose-Luis; Inglese, James; Callahan, Brian P.
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The NCATS Assay Guidance Manual programme: advancing the practice and rigour of preclinical translation
err2022-10-17
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PREAI
errMarkossian, Sarine; Brimacombe, Kyle R.; Sittampalam, G. Sitta; Grossman, Abigail; Coussens, Nathan P.; Inglese, James; Auld, Douglas S.; Chin, William; Austin, Christopher P.; Hall, Matthew D.
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Serum-Stable and Selective Backbone-N-Methylated Cyclic Peptides That Inhibit Prokaryotic Glycolytic Mutases
err2022-07-29
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errvan Neer, R. H. P.; Dranchak, P. K.; Liu, L.; Aitha, M.; Queme, B.; Kimura, H.; Katoh, T.; Battaile, K. P.; Lovell, S.; Inglese, J.; Suga, H.
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Establishing an RNA interference (RNAi) screen for neuroprotection of dopaminergic neurons in Caenorhabditis elegans models of Parkinson's disease
err2022-05-13
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PREAI
errAnderson, Emily E.; Ash, Carl T.; Moritz, Amy E.; Dranchak, Patricia; Free, R. Benjamin; Inglese, James; Steiner, Joseph P.; Sibley, David R.; Akano, Emmanuel O.
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Development of a dopaminergic neurodegeneration assay using laser cytometry of Caenorhabditis elegans models of Parkinson's disease
err2021-05-14
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PREAI
errAkano, Emmanuel; Casazza, Julia; Dranchak, Patricia; Anderson, Emily; Moritz, Amy; Free, R.; Steiner, Joseph; Inglese, James; Sibley, David
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Structure-activity relationship of ipglycermide binding to phosphoglycerate mutases
err2021-01-01
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errWiedmann, Mareike; Dranchak, Patricia K.; Aitha, Mahesh; Queme, Bryan; Collmus, Christopher D.; Kashipathy, Maithri M.; Kanter, Liza; Lamy, Laurence; Rogers, Joseph M.; Tao, Dingyin; Battaile, Kevin P.; Rai, Ganesha; Lovell, Scott; Suga, Hiroaki; Inglese, James
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A Macrocyclic Peptide Library with a Structurally Constrained Cyclopropane-containing Building Block Leads to Thiol-independent Inhibitors of Phosphoglycerate Mutase
err2020-08-11
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errOkuma, Rika; Kuwahara, Tomoki; Yoshikane, Takafumi; Watanabe, Mizuki; Dranchak, Patricia; Inglese, James; Shuto, Satoshi; Goto, Yuki; Suga, Hiroaki
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