Not logged inGenomic alterations and transcriptional phenotypes in circulating free DNA and matched metastatic tumor
Takahashi, Nobuyuki; Pongor, Lorinc; Agrawal, Shivam P.; Shtumpf, Mariya; Gurjar, Ankita; Rajapakse, Vinodh N.; Shafiei, Ahmad; Schultz, Christopher W.; Kim, Sehyun; Roame, Diana; Carter, Paula; Vilimas, Rasa; Nichols, Samantha; Desai, Parth; Figg Sr, William Douglas; Bagheri, Mohammad; Teif, Vladimir B.; Thomas, Anish .png)
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SaveMicroenvironment shapes small-cell lung cancer neuroendocrine states and presents therapeutic opportunitiesDesai, Parth; Takahashi, Nobuyuki; Kumar, Rajesh; Nichols, Samantha; Malin, Justin; Hunt, Allison; Schultz, Christopher; Cao, Yingying; Tillo, Desiree; Nousome, Darryl; Chauhan, Lakshya; Sciuto, Linda; Jordan, Kimberly; Rajapakse, Vinodh; Tandon, Mayank; Lissa, Delphine; Zhang, Yang; Kumar, Suresh; Pongor, Lorinc; Singh, Abhay; Schroder, Brett; Sharma, Ajit Kumar; Chang, Tiangen; Vilimas, Rasa; Pinkiert, Danielle; Graham, Chante; Butcher, Donna; Warner, Andrew; Sebastian, Robin; Mahon, Mimi; Baker, Karen; Cheng, Jennifer; Berger, Ann; Lake, Ross; Abel, Melissa; Krishnamurthy, Manan; Chrisafis, George; Fitzgerald, Peter; Nirula, Micheal; Goyal, Shubhank; Atkinson, Devon; Bateman, Nicholas W.; Abulez, Tamara; Nair, Govind; Apolo, Andrea; Guha, Udayan; Karim, Baktiar; El Meskini, Rajaa; Ohler, Zoe Weaver; Jolly, Mohit Kumar; Schaffer, Alejandro; Ruppin, Eytan; Kleiner, David; Miettinen, Markku; Brown, G. Tom; Hewitt, Stephen; Conrads, Thomas; Thomas, Anish Share Save Proteomic Dynamics of Breast Cancer Cell Lines Identifies Potential Therapeutic Protein TargetsSun, Rui; Ge, Weigang; Zhu, Yi; Sayad, Azin; Luna, Augustin; Lyu, Mengge; Liang, Shuang; Tobalina, Luis; Rajapakse, Vinodh N.; Yu, Chenhuan; Zhang, Huanhuan; Fang, Jie; Wu, Fang; Xie, Hui; Saez-Rodriguez, Julio; Ying, Huazhong; Reinhold, William C.; Sander, Chris; Pommier, Yves; Neel, Benjamin G.; Aebersold, Ruedi; Guo, Tiannan Share Save Distinct immunosuppressive tumor microenvironment modulates small cell lung carcinoma neuroendocrine phenotypic plasticity and heterogeneityDesai, Parth Anil; Takahashi, Nobuyuki; Cao, Yingying; Schultz, Christopher; Nousome, Darryl; Tillo, Desiree; Chauhan, Lakshya; tandon, Mayank; Bhardwaj, Rajesh kumar; Lissa, Delphine; Rajapakse, Vinodh; Kumar, Suresh; Zhang, Yang; Rajaa, Elmeskini; Butcher, Donna; Scuito, Linda; Gong, Jingjing; Schroder, Brett; Warner, Andrew; Nichols, Samantha; Kimberly, Jordan; Schaffer, Alejandro; Jolly, Mohit kumar; Hewitt, Stephen; Thomas, Anish Share Save Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse OutcomesPongor, Lorinc Sandor; Schultz, Christopher W.; Rinaldi, Lorenzo; Wangsa, Darawalee; Redon, Christophe E.; Takahashi, Nobuyuki; Fialkoff, Gavriel; Desai, Parth; Zhang, Yang; Burkett, Sandra; Hermoni, Nadav; Vilk, Noa; Gutin, Jenia; Gergely, Rona; Zhao, Yongmei; Nichols, Samantha; Vilimas, Rasa; Sciuto, Linda; Graham, Chante; Caravaca, Juan Manuel; Turan, Sevilay; Shen, Tsai-wei; Rajapakse, Vinodh N.; Kumar, Rajesh; Upadhyay, Deep; Kumar, Suresh; Kim, Yoo Sun; Roper, Nitin; Tran, Bao; Hewitt, Stephen M.; Kleiner, David E.; Aladjem, Mirit I.; Friedman, Nir; Hager, Gordon L.; Pommier, Yves; Ried, Thomas; Thomas, Anish Share Save Heterogeneity of neuroendocrine transcriptional states in metastatic small cell lung cancers and patient-derived modelsLissa, Delphine; Takahashi, Nobuyuki; Desai, Parth; Manukyan, Irena; Schultz, Christopher W.; Rajapakse, Vinodh; Velez, Moises J.; Mulford, Deborah; Roper, Nitin; Nichols, Samantha; Vilimas, Rasa; Sciuto, Linda; Chen, Yuanbin; Guha, Udayan; Rajan, Arun; Atkinson, Devon; El Meskini, Rajaa; Ohler, Zoe Weaver; Thomas, Anish Share Save Novel and Highly Potent ATR Inhibitor M4344 Kills Cancer Cells With Replication Stress, and Enhances the Chemotherapeutic Activity of Widely Used DNA Damaging AgentsJo, Ukhyun; Senatorov, Ilya S.; Zimmermann, Astrid; Saha, Liton Kumar; Murai, Yasuhisa; Kim, Se Hyun; Rajapakse, Vinodh N.; Elloumi, Fathi; Takahashi, Nobuyuki; Schultz, Christopher W.; Thomas, Anish; Zenke, Frank T.; Pommier, Yves Share Save Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair-targeted therapiesTlemsani, Camille; Takahashi, Nobuyuki; Pongor, Lorinc; Rajapakse, Vinodh N.; Tyagi, Manoj; Wen, Xinyu; Fasaye, Grace-Ann; Schmidt, Keith T.; Desai, Parth; Kim, Chul; Rajan, Arun; Swift, Shannon; Sciuto, Linda; Vilimas, Rasa; Webb, Santhana; Nichols, Samantha; Figg, William Douglas; Pommier, Yves; Calzone, Kathleen; Steinberg, Seth M.; Wei, Jun S.; Guha, Udayan; Turner, Clesson E.; Khan, Javed; Thomas, Anish Share Save CellMiner Cross-Database (CellMinerCDB) version 1.2: Exploration of patient-derived cancer cell line pharmacogenomicsLuna, Augustin; Elloumi, Fathi; Varma, Sudhir; Wang, Yanghsin; Rajapakse, Vinodh N.; Aladjem, Mirit, I; Robert, Jacques; Sander, Chris; Pommier, Yves; Reinhold, William C. Share Save SCLC-CellMiner: A Resource for Small Cell Lung Cancer Cell Line Genomics and Pharmacology Based on Genomic SignaturesTlemsani, Camille; Pongor, Lorinc; Elloumi, Fathi; Girard, Luc; Huffman, Kenneth E.; Roper, Nitin; Varma, Sudhir; Luna, Augustin; Rajapakse, Vinodh N.; Sebastian, Robin; Kohn, Kurt W.; Krushkal, Julia; Aladjem, Mirit, I; Teicher, Beverly A.; Meltzer, Paul S.; Reinhold, William C.; Minna, John D.; Thomas, Anish; Pommier, Yves Share Save Clinical and Genomic Characteristics of Small Cell Lung Cancer in Never Smokers Results From a Retrospective Multicenter Cohort StudyThomas, Anish; Mian, Idrees; Tlemsani, Camille; Pongor, Lorinc; Takahashi, Nobuyuki; Maignan, Kathleen; Snider, Jeremy; Li, Gerald; Frampton, Garrett; Ali, Siraj; Kim, Sehyun; Nichols, Samantha; Rajapakse, Vinodh; Guha, Udayan; Sharon, Elad; Fujimoto, Junya; Moran, Cesar A.; Wistuba, Ignacio I.; Wei, Jun S.; Khan, Javed; Szabo, Eva; Torres, Aracelis Z.; Carson, Kenneth R. Share Save Immunohistochemical analysis of SLFN11 expression uncovers potential non-responders to DNA-damaging agents overlooked by tissue RNA-seqTakashima, Tsuyoshi; Sakamoto, Naoya; Murai, Junko; Taniyarna, Daiki; Honma, Ririno; Ukai, Shoichi; Maruyama, Ryota; Kuraoka, Kazuya; Rajapakse, Vinodh N.; Pommier, Yves; Yasui, Wataru Share Save Share Save Share Save Identification of Schlafen-11 as a Target of CD47 Signaling That Regulates Sensitivity to Ionizing Radiation and Topoisomerase InhibitorsKaur, Sukhbir; Schwartz, Anthony L.; Jordan, David G.; Soto-Pantoja, David R.; Kuo, Bethany; Elkahloun, Abdel G.; Griner, Lesley Mathews; Thomas, Craig J.; Ferrer, Marc; Thomas, Anish; Tang, Sai-Wen; Rajapakse, Vinodh N.; Pommier, Yves; Roberts, David D. Share Save Share Save Share Save SLFN11 Blocks Stressed Replication Forks Independently of ATRMurai, Junko; Tang, Sai-Wen; Leo, Elisabetta; Baechler, Simone A.; Redon, Christophe E.; Zhang, Hongliang; Al Abo, Muthana; Rajapakse, Vinodh N.; Nakamura, Eijiro; Jenkins, Lisa M. Miller; Aladjem, Mirit I.; Pommier, Yves Share Save ONC201 kills breast cancer cells by targeting mitochondriaGreer, Yoshimi Endo; Gilbert, Samuel; Islam, Celia; Ubaldini, Ashley; Stuelten, Christina; Porat-Shliom, Natalie; Weigert, Roberto; Ji, Yun; Gattinoni, Luca; Soheilian, Ferri; Nagashima, Kunio; Wang, Xiantao; Hafner, Markus; Shetty, Jyoti; Tran, Bao; Koparde, Vishal; Jailwala, Parthav; Cam, Maggie; Crooks, Dan; Linehan, W. Marston; Voeller, Donna; Reinhold, William; Rajapakse, Vinodh; Pommier, Yves; Lipkowitz, Stanley Share Save TDP1 is Critical for the Repair of DNA Breaks Induced by Sapacitabine, a Nucleoside also Targeting ATM- and BRCA-Deficient TumorsAl Abo, Muthana; Sasanuma, Hiroyuki; Liu, Xiaojun; Rajapakse, Vinodh N.; Huang, Shar-yin; Kiselev, Evgeny; Takeda, Shunichi; Plunkett, William; Pommier, Yves Share Save 
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