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Eslam B. Elkaeed

Almaarefa University

43H-index
283Paper Count
6.5KCitation Count
Published Papers 152
Publication Date
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Identification of Apixaban as a Potential Inhibitor of the SARS-CoV-2 Main Protease: A Multistage Computational Study
errJournal of Chemistry
IF2.6
err2026-05-26
err0
errOAAI
errAhmed M. Metwaly; Bshra A. Alsfouk; Ibrahim M. Ibrahim; Eslam B. Elkaeed; Ibrahim H. Eissa
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New N-(isoxazol-3-yl)-4-(1,3,4-thiadiazol-3(2H)-yl)benzenesulfonamide derivatives as potent Aurora kinases inhibitors: Design, synthesis and anti-proliferative activity
errBioorganic Chemistry
IF4.7
err2026-05-25
err0
PREAI
errBshra A. Alsfouk; Hazem Elkady; Walid E. Elgammal; Ahmed Nofal; Hazem A. Mahdy; Dalal Z. Husein; Fatma G. Amin; Eslam B. Elkaeed; Ibrahim H. Eissa; Ahmed M. Metwaly
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Structure-Guided Design and Mechanistic Elucidation of New Chromene Derivatives as Selective Vascular Endothelial Growth Factor Receptor-2 Inhibitors With Potent Anticancer Activity
errDrug Development Research
IF4.2
err2026-05-03
err0
PREAI
errHazem Elkady; Walid E. Elgammal; Ibrahim H. Eissa; Hazem A. Mahdy; Aisha A. Alsfouk; Fatma G. Amin; Dalal Z. Husein; Ahmed M. Metwaly; Eslam B. Elkaeed
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Thiadiazole-Derived VEGFR-2 Inhibitors: From Design to Anticancer Evaluation
errChemical Biology & Drug Design
IF3.3
err2026-03-26
err0
PREAI
errAlsfouk, Aisha A.; Elkaeed, Eslam B.; Elkady, Hazem; Elgammal, Walid E.; Mahdy, Hazem A.; Nofal, Ahmed; Eissa, Ibrahim H.; Husein, Dalal Z.; Ibrahim, Ibrahim M.; Elkotamy, Mahmoud S.; Metwaly, Ahmed M.
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Aotaphenazine, a rare hydrophenazine, targets topoisomerase II with anticancer efficacy: In silico to in vitro evidence
errPLOS ONE
IF2.6
err2025-12-05
err0
PREAI
errMetwaly, Ahmed M.; Eissa, Ibrahim H.; Afifi, Wael M.; Elkaeed, Eslam B.; Alsfouk, Aisha A.; Ibrahim, Ibrahim M.; Abdelfattah, Mohamed S.
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2,3-Dihydro-1,3,4-thiadiazoles as dual B-Raf / VEGFR-2 inhibitors: Design, synthesis, and anti-breast cancer assessment
errJournal of Molecular Structure
IF4.7
err2025-11-14
err0
PREAI
errWalid E. Elgammal; Hazem Elkady; Hazem A. Mahdy; Alaa Elwan; Dalal Z. Husein; Fatma G. Amin; Bshra A. Alsfouk; Eslam B. Elkaeed; Ibrahim H. Eissa; Ahmed M. Metwaly
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Development of novel furan-based VEGFR-2 inhibitors and apoptotic inducers for colorectal cancer
errFUTURE MEDICINAL CHEMISTRY
IF3.4
err2025-11-01
err0
PREAI
errElkaeed, Eslam B.; Al Ward, Maged Mohammed Saleh; Elkady, Hazem; Yousef, Reda G.; Elsheshiny, Asmaa A. A.; Abdelfattah, Shimaa. S.; El-Fakharany, Esmail M.; Alsfouk, Aisha A.; Metwaly, Ahmed M.; Eissa, Ibrahim H.
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A novel thiadiazole-based dual inhibitor of carbonic anhydrase-IX and epidermal growth factor receptor targeting cancer: A combined in silico and in vitro approach
errJOURNAL OF CHEMICAL RESEARCH
IF1.2
err2025-11-01
err0
PREAI
errElkaeed, Eslam B.; Elkady, Hazem; Elgammal, Walid E.; Mahdy, Hazem A.; Husein, Dalal Z.; Ibrahim, Ibrahim M.; Al-ghulikah, Hanan A.; Eissa, Ibrahim H.; Metwaly, Ahmed M.
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Design, Computational, Synthesis, and Anti-Cancer Evaluation of a Multifunctional 2,3-Dihydro-1,3,4-Thiadiazole-Benzenesulfonamide Hybrid as a Triple Inhibitor of CAIX, CAXII, and EGFR
errJournal of Computational Biophysics and Chemistry
IF2.3
err2025-11-01
err0
PREAI
errEissa, Ibrahim H.; Elkady, Hazem; Elgammal, Walid E.; Mahdy, Hazem A.; Husein, Dalal Z.; Ibrahim, Ibrahim M.; Abdullah, Rosine; Alsfouk, Aisha A.; Elkaeed, Eslam B.; Metwaly, Ahmed M.
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Integrated Computational and Experimental Discovery of a Promising Xanthine Derivative with Anticancer Potential Targeting EGFR
errCURRENT CANCER DRUG TARGETS
IF3.5
err2025-10-01
err0
PREAI
errElkaeed, Eslam B.; Yousef, Reda G.; Elkady, Hazem; Al-ghulikah, Hanan A.; Ibrahim, Ibrahim M.; Soliman, Omar A.; Husein, Dalal Z.; Doghish, Ahmed S.; Metwaly, Ahmed M.; Eissa, Ibrahim H.
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Exploring the Anticancer Potential of Chitosome-Encapsulated Theobromine Analogue: Integrated Computational, Physiochemical and In vitro Study
errNATURAL PRODUCT COMMUNICATIONS
IF1.4
err2025-10-01
err1
PREAI
errMetwaly, Ahmed M.; Abd-El-Azim, Heba; Zewail, Mariam; Alsfouk, Aisha A.; Elkaeed, Eslam B.; Elkady, Hazem; Eissa, Ibrahim H.
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VEGFR-2-Targeted Semisynthetic Theobromine Derivative: A Computer-Aided Drug Design (CADD) Approach
errJournal of Computational Biophysics and Chemistry
IF2.3
err2025-10-01
err0
PREAI
errElkaeed, Eslam B.; Yousef, Reda G.; Elkady, Hazem; Al-ghulikah, Hanan A.; Husein, Dalal Z.; Ibrahim, Ibrahim M.; Metwaly, Ahmed M.; Eissa, Ibrahim H.
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New 1,3,4-Thiadiazole-Based Dual B-Raf/VEGFR-2 Inhibitors With Potential Anti-Breast Activity: Design, Synthesis, In Vitro and In Silico Evaluations
errArchiv der Pharmazie
IF3.6
err2025-09-28
err0
PREAI
errWalid E. Elgammal; Hazem Elkady; Hazem A. Mahdy; Bshra A. Alsfouk; Dalal Z. Husein; Fatma G. Amin; Abdelrahman A. Abuelkhir; Eslam B. Elkaeed; Ahmed M. Metwaly; Ibrahim H. Eissa
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Development of new thiadiazole-based compounds targeting VEGFR-2: In vitro anticancer evaluation, mechanistic investigations, and in silico studies
errJournal of Molecular Structure
IF4.7
err2025-08-09
err0
PREAI
errBshra A. Alsfouk; Walid E. Elgammal; Hazem Elkady; Hazem A. Mahdy; Saber M. Hassan; Dalal Z. Husein; Omar A. Soliman; Mohamed Hagras; Mohamed A. Elkady; Hany G. Ezzat; Ibrahim H. Eissa; Ahmed M. Metwaly; Eslam B. Elkaeed
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Integrated computational and biological evaluations of newly synthesized thiadiazole-based VEGFR-2 inhibitors with targeted anti-breast cancer activity
errNaunyn-Schmiedeberg's Archives of Pharmacology
IF3.1
err2025-07-23
err0
PREAI
errBshra A. Alsfouk; Walid E. Elgammal; Hazem Elkady; Hazem A. Mahdy; Dalal Z. Husein; Omar A. Soliman; Abdelrahman A. Abuelkhir; Ibrahim H. Eissa; Eslam B. Elkaeed; Ahmed M. Metwaly
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New Thiadiazole-Benzenesulfonamide Hybrids as Dual B-Raf/VEGFR-2 Inhibitors With Promising Anti-Hepatic Cancer Activity
errChemical Biology & Drug Design
IF3.3
err2025-07-20
err0
PREAI
errAisha A. Alsfouk; Hazem Elkady; Saber M. Hassan; Walid E. Elgammal; Hazem A. Mahdy; Dalal Z. Husein; Fatma G. Amin; Mohamed Hagras; Eslam B. Elkaeed; Ahmed M. Metwaly; Ibrahim H. Eissa
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Development of New Thiadiazole Derivatives as VEGFR-2 Inhibitors With Anticancer and Proapoptotic Activities‏
errArchiv der Pharmazie
IF3.6
err2025-07-01
err0
PREAI
errHazem Elkady; Walid E. Elgammal; Mohamed M. Khalifa; Hazem A. Mahdy; Ahmed S. Ibrahim; Abdullah Y. Saad; Bshra A. Alsfouk; Eslam B. Elkaeed
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Discovery of new thieno[2,3-d]pyrimidine-based dual VEGFR-2 and EGFR inhibitors for enhanced therapeutic efficacy in breast cancer
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2025-06-03
err0
PREAI
errYousef, Reda G.; El-Metwally, Souad A.; Al Ward, Maged Mohammed Saleh; Alsfouk, Aisha A.; Husein, Dalal Z.; Soliman, Omar A.; Elkaeed, Eslam B.; Metwaly, Ahmed M.
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Development of new anticancer thiadiazole-sulfonamides as dual EGFR/carbonic anhydrase inhibitors
errFUTURE MEDICINAL CHEMISTRY
IF3.4
err2025-05-08
err0
PREAI
errEissa, Ibrahim H.; Elkady, Hazem; Elgammal, Walid E.; Mahdy, Hazem A.; Elshennawy, Hany S.; Husein, Dalal Z.; Amin, Fatma G.; Ibrahim, Ibrahim M.; Alsfouk, Bshra A.; Elkaeed, Eslam B.; Metwaly, Ahmed M.
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Design and synthesis of thiadiazoles as anticancer, apoptotic, and VEGFR-2 inhibitors
errFUTURE MEDICINAL CHEMISTRY
IF3.4
err2025-04-08
err0
PREAI
errElgammal, Walid E.; Elkady, Hazem; Dahab, Mohammed A.; Mahdy, Hazem A.; Hagras, Mohamed; Nofal, Ahmed; Alsfouk, Bshra A.; Elkaeed, Eslam B.; Eissa, Ibrahim H.; Metwaly, Ahmed M.
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Research Directions

No research directions
Co-authors
Cooperation Journals
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Wim Dehaen
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Wolfgang Sippl
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