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Epstein-Barr virus reactivation induces MYC-IGH spatial proximity and t(8;14) in B cells Sall, Fatimata Bintou; Shmakova, Anna; Karpukhina, Anna; Tsfasman, Tatyana; Lomov, Nikolai; Canoy, Reynand Jay; Boutboul, David; Oksenhendler, Eric; Toure, Awa Oumar; Lipinski, Marc; Wiels, Joelle; Germini, Diego; Vassetzky, Yegor Share Save
In vitro evaluation of NA1-115-7-loaded nanoemulsions, an MCL-1-specific inhibitor of natural origin, intended to treat B-cell lymphoproliferative disorders after oral administration Seguy, Line; Daressy, Florian; Lahlil, Sophia; Corvaisier, Sophie; Dumontet, Vincent; Litaudon, Marc; Apel, Cecile; Roussi, Fanny; Wiels, Joelle; Robert, Aude; Groo, Anne-Claire; Malzert-Freon, Aurelie Share Save
NA1-115-7, from Zygogynum pancheri, is a new selective MCL-1 inhibitor inducing the apoptosis of hematological cancer cells but non-toxic to normal blood cells or cardiomyocytes Daressy, Florian; Seguy, Line; Favre, Loetitia; Corvaisier, Sophie; Apel, Cecile; Groo, Anne-Claire; Litaudon, Marc; Dumontet, Vincent; Malzert-Freon, Aurelie; Desrat, Sandy; Roussi, Fanny; Robert, Aude; Wiels, Joelle Share Save
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Drimane Derivatives as the First Examples of Covalent BH3 Mimetics that Target MCL-1 Daressy, Florian; Malard, Florian; Seguy, Line; Guerineau, Vincent; Apel, Cecile; Dumontet, Vincent; Robert, Aude; Groo, Anne-Claire; Litaudon, Marc; Bignon, Jerome; Desrat, Sandy; Malzert-Freon, Aurelie; Wiels, Joelle; Lescop, Ewen; Roussi, Fanny Share Save
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Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma (vol 33, pg 2429, 2019) Harrington, Colleen T.; Sotillo, Elena; Robert, Aude; Hayer, Katharina E.; Bogusz, Agata M.; Psathas, James; Yu, Duonan; Taylor, Deanne; Dang, Chi V.; Klein, Peter S.; Hogarty, Michael D.; Geoerger, Birgit; El-Deiry, Wafik S.; Wiels, Joelle; Thomas-Tikhonenko, Andrei Share Save
Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma Harrington, Colleen T.; Sotillo, Elena; Robert, Aude; Hayer, Katharina E.; Bogusz, Agata M.; Psathas, James; Yu, Duonan; Taylor, Deanne; Dang, Chi, V; Klein, Peter; Hogarty, Michael D.; Geoerger, Birgit; El-Deiry, Wafik S.; Wiels, Joelle; Thomas-Tikhonenko, Andrei Share Save
Developmental and cancer-associated plasticity of DNA replication preferentially targets GC-poor, lowly expressed and late-replicating regions (vol 46, pg 10157, 2018) Wu, Xia; Kabalane, Hadi; Kahli, Malik; Petryk, Nataliya; Laperrousaz, Bastien; Jaszczyszyn, Yan; Drillon, Guenola; Nicolini, Frank-Emmanuel; Perot, Gaelle; Robert, Aude; Fund, Cedric; Chibon, Frederic; Xia, Ruohong; Wiels, Joelle; Argoul, Francoise; Maguer-Satta, Veronique; Arneodo, Alain; Audit, Benjamin; Hyrien, Olivier Share Save
Developmental and cancer-associated plasticity of DNA replication preferentially targets GC-poor, lowly expressed and late-replicating regions Wu, Xia; Kabalane, Hadi; Kahli, Malik; Petryk, Nataliya; Laperrousaz, Bastien; Jaszczyszyn, Yan; Drillon, Guenola; Nicolini, Frank-Emmanuel; Perot, Gaelle; Robert, Aude; Fund, Cederic; Chibon, Frederic; Xia, Ruohong; Wiels, Joelle; Argoul, Francois; Maguer-Satta, Veronique; Arneodo, Alain; Audit, Benjamin; Hyrien, Olivier Share Save
Dual inhibitors of the pro-survival proteins Bcl-2 and Mcl-1 derived from natural compound meiogynin A Abou Samra, Alma; Robert, Aude; Gov, Crystal; Favre, Loetitia; Eloy, Laure; Jacquet, Eric; Bignon, Jerome; Wiels, Joelle; Desrat, Sandy; Roussi, Fanny Share Save
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Natural Variation of Epstein-Barr Virus Genes, Proteins, and Primary MicroRNA Correia, Samantha; Palser, Anne; Karstegl, Claudio Elgueta; Middeldorp, Jaap M.; Ramayanti, Octavia; Cohen, Jeffrey I.; Hildesheim, Allan; Fellner, Maria Dolores; Wiels, Joelle; White, Robert E.; Kellam, Paul; Farrell, Paul J. Share Save
HIV Tat induces a prolonged MYC relocalization next to IGH in circulating B-cells Germini, D.; Tsfasman, T.; Klibi, M.; El-Amine, R.; Pichugin, A.; Iarovaia, O. V.; Bilhou-Nabera, C.; Subra, F.; Saada, Y. Bou; Sukhanova, A.; Boutboul, D.; Raphael, M.; Wiels, J.; Razin, S. V.; Bury-Mone, S.; Oksenhendler, E.; Lipinski, M.; Vassetzky, Y. S. Share Save
Constitutive autophagy contributes to resistance to TP53-mediated apoptosis in Epstein-Barr virus-positive latency III B-cell lymphoproliferations Pujals, Anais; Favre, Loetitia; Pioche-Durieu, Catherine; Robert, Aude; Meurice, Guillaume; Le Gentil, Marion; Chelouah, Sonia; Martin-Garcia, Nadine; Le Cam, Eric; Guettier, Catherine; Raphael, Martine; Vassilev, Lyubomir T.; Gaulard, Philippe; Codogno, Patrice; Lipinski, Marc; Wiels, Joelle Share Save
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