Matthew Grimmer - Publications, H-index & Citations

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Matthew Grimmer

genentech, inc.

20H-index

103Paper Count

3.3KCitation Count

Published Papers 14

Publication Date

Tumor-targeted bispecific antibodies effectively inhibit oncogenic pathways while minimizing toxicity

Science Advances

IF12.5

2026-05-22

OAAI

Yvonne T. Kschonsak; Wei-Ching Liang; Joyce Chan; David Kan; Thao Nguyen; Karen Ruiz; Yee-Seir Kee; Wen-Ting K. Tsai; Hongkang Xi; Marina Moskalenko; Travis Morgenstern; Aurelie Herault; Lauriane Cabon; Ryo Okuda; Scott S. Stawicki; Jocelyn Chan; Matthew Grimmer; Diego Ellerman; James Mondo; Catherine F. Ruff; Gabriele Schaefer; Udi Segal; Robert Piskol; Nicholas J. Agard; Laetitia Comps-Agrar; Felipe de Sousa e Melo; James T. Koerber

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Template-driven scaffolding of SCFFBXO42 regulates PP2A degradation

Nature

IF48.5

2026-04-01

PREAI

Coassolo, Sebastien; Michaelian, Nairie; Maculins, Timurs; Azumaya, Caleigh M.; Cheung, Tommy K.; Yin, Jianping; Zilberleyb, Inna; Pahuja, Kanika Bajaj; Garner, Thomas; Lau, Ted; Mau, Davis; Grimmer, Matthew; Fortin, Jean-Philippe; Costa, Mike; Dimitrova, Yoana N.; Rose, Christopher M.; Hsu, Peter L.; Yauch, Robert L.

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INTRAOPERATIVE OR POSTOPERATIVE STEREOTACTIC RADIOTHERAPY FOR BRAIN METASTASES: TIME TO SYSTEMIC TREATMENT ONSET AND OTHER PATIENT-RELEVANT OUTCOMES

NEURO-ONCOLOGY

IF13.4

2024-10-17

PREAI

Dejonckheere, C.; Layer, J.; Hamed, M.; Schneider, M.; Vatter, H.; Herrlinger, U.; Grimmer, M.; Kugel, F.; Garbe, S.; Giordano, F.; Sarria, G. R.

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Large-scale manipulation of promoter DNA methylation reveals context-specific transcriptional responses and stability

GENOME BIOLOGY

IF9.4

2022-07-26

OAAI

de Mendoza, Alex; Trung Viet Nguyen; Ford, Ethan; Poppe, Daniel; Buckberry, Sam; Pflueger, Jahnvi; Grimmer, Matthew R.; Stolzenburg, Sabine; Bogdanovic, Ozren; Oshlack, Alicia; Farnham, Peggy J.; Blancafort, Pilar; Lister, Ryan

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Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant gliomas

NEURO-ONCOLOGY

IF13.4

2021-04-05

OAAI

Yu, Yao; Villanueva-Meyer, Javier; Grimmer, Matthew R.; Hilz, Stephanie; Solomon, David A.; Choi, Serah; Wahl, Michael; Mazor, Tali; Hong, Chibo; Shai, Anny; Phillips, Joanna J.; Wainer, Bruce H.; McDermott, Michael; Haas-Kogan, Daphne; Taylor, Jennie W.; Butowski, Nicholas; Clarke, Jennifer L.; Berger, Mitchel S.; Molinaro, Annette M.; Chang, Susan M.; Costello, Joseph F.; Bush, Nancy Ann Oberheim

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Patient-derived cells from recurrent tumors that model the evolution of IDH-mutant glioma

NEURO-ONCOLOGY ADVANCES

IF4.1

2020-07-16

OAAI

Jones, Lindsey E.; Hilz, Stephanie; Grimmer, Matthew R.; Mazor, Tali; Najac, Chloe; Mukherjee, Joydeep; McKinney, Andrew; Chow, Tracy; Pieper, Russell O.; Ronen, Sabrina M.; Chang, Susan M.; Phillips, Joanna J.; Costello, Joseph F.

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MGMT promoter methylation level in newly diagnosed low-grade glioma is a predictor of hypermutation at recurrence

NEURO-ONCOLOGY

IF13.4

2020-03-13

OAAI

Mathur, Radhika; Zhang, Yalan; Grimmer, Matthew R.; Hong, Chibo; Zhang, Michael; Bollam, Saumya; Petrecca, Kevin; Clarke, Jennifer; Berger, Mitchel S.; Phillips, Joanna J.; Oberheim-Bush, Nancy Ann; Molinaro, Annette M.; Chang, Susan M.; Costello, Joseph F.

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Clinico-genomic analysis of temozolomide-induced hypermutation in both molecular subtypes of IDH-mutant glioma

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Grimmer, Matthew R.

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Temozolomide-associated hypermutation in gliomas

NEURO-ONCOLOGY

IF13.4

2018-02-14

148

OAAI

Choi, Serah; Yu, Yao; Grimmer, Matthew R.; Wahl, Michael; Chang, Susan M.; Costello, Joseph F.

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Effects on the transcriptome upon deletion of a distal element cannot be predicted by the size of the H3K27Ac peak in human cells

NUCLEIC ACIDS RESEARCH

IF13.1

2016-01-06

OAAI

Tak, Yu Gyoung; Hung, Yuli; Yao, Lijing; Grimmer, Matthew R.; Do, Albert; Bhakta, Mital S.; O'Geen, Henriette; Segal, David J.; Farnham, Peggy J.

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Downregulation of MYCN through PI3K inhibition in mouse models of pediatric neural cancer

FRONTIERS IN ONCOLOGY

IF3.3

2015-05-12

OAAI

Cage, Tene Aneka; Chanthery, Yvan; Chesler, Louis; Grimmer, Matthew; Knight, Zachary; Shokat, Kevan; Weiss, William A.; Gustafson, W. Clay

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Can genome engineering be used to target cancer-associated enhancers?

EPIGENOMICS

IF2.6

2014-11-28

OAAI

Grimmer, Matthew R.; Farnham, Peggy J.

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Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation

NUCLEIC ACIDS RESEARCH

IF13.1

2014-08-13

OAAI

Grimmer, Matthew R.; Stolzenburg, Sabine; Ford, Ethan; Lister, Ryan; Blancafort, Pilar; Farnham, Peggy J.

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Interactions between N-myc and Sox9 promote medulloblastoma and determine cell fate decisions in cerebellar neural stem cells

CANCER RESEARCH

IF16.6

2011-04-01

PREAI

Swartling, Fredrik J.; Persson, Anders I.; Lau, Jasmine; Northcott, Paul A.; Grimmer, Matthew R.; Chesler, Louis; Perry, Arie; Phillips, Joanna J.; Taylor, Michael D.; Weiss, William A.

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Research Directions