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M

Marianne G. Rots

pathology and medical biology

41H-index
158Paper Count
5.9KCitation Count
Published Papers 62
Publication Date
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Epigenetic signatures and cellular stress response pathways in metabolic dysfunction-associated steatotic liver disease: a personalized medicine perspective
errFrontiers in Physiology
IF3.4
err2026-04-30
err0
errOAAI
errFM Fabian M. Cortés-Mancera †; MG Marianne G. Rots; HM Han Moshage; JC Johanna C. Arroyave-Ospina †
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Editing without Breaking: Sustained Gene Control via Epigenetic Rewriting
errCurrent Opinion in Biomedical Engineering
IF4.2
err2026-04-13
err0
errOAAI
errWen Y. Wu; Marianne G. Rots
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errSave
Epigenetic editing: from concept to clinic
errNature Reviews Drug Discovery
IF101.8
err2025-11-24
err0
PREAI
errElizabeth A. Heller; Lacramioara Bintu; Marianne G. Rots
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Effective Reduction in Nuclear DNA Contamination Allows Sensitive Mitochondrial DNA Methylation Determination by LC-MS/MS
errInternational Journal of Molecular Sciences 2025, Vol. 26, Page 8864
IF4.9
err2025-09-21
err0
errOAAI
errLin Liang; Luis Alfonso González Molina; Pytrick G. Jellema; Martijn van Faassen; Laura T. A. Otten; Kevin P. Mennega; Ingrid H. Hof; D. A. Janneke Dijck-Brouwer; Amalia M. Dolga; Marianne G. Rots; Klary E. Niezen-Koning
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Clinical promise and applications of epigenetic biomarkers
errCLINICAL EPIGENETICS
IF4.4
err2024-12-28
err0
errOAAI
errWisman, G. Bea A.; Wojdacz, Tomasz K.; Altucci, Lucia; Rots, Marianne G.; Demeo, Dawn L.; Snieder, Harold
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Mitochondrial DNA methylation in metabolic associated fatty liver disease
errFRONTIERS IN NUTRITION
IF5.1
err2023-05-25
err8
errOAAI
errMposhi, Archibold; Cortes-Mancera, Fabian; Heegsma, Janette; de Meijer, Vincent E.; van de Sluis, Bart; Sydor, Svenja; Bechmann, Lars P.; Theys, Claudia; de Rijk, Peter; De Pooter, Tim; Vanden Berghe, Wim; Ince, Ikbal Agah; Faber, Klaas Nico; Rots, Marianne G.
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Efficient methods for multiple types of precise gene-editing in Chlamydomonas
errPLANT JOURNAL
IF5.7
err2023-05-24
err12
errOAAI
errChen, Hui; Yang, Qing-Lin; Xu, Jia-Xi; Deng, Xuan; Zhang, Yun-Jie; Liu, Ting; Rots, Marianne G.; Xu, Guo-Liang; Huang, Kai-Yao
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Liver transcriptomic and methylomic analyses identify transcriptional mitogen-activated protein kinase regulation in facultative hibernation of Syrian hamster
errPROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
IF3.5
err2023-05-24
err2
errOAAI
errCoussement, Louis; Oosterhof, Marloes M.; Guryev, Victor; Reitsema, Vera A.; Bruintjes, Jojanneke J.; Goris, Maaike; Bouma, Hjalmar R.; de Meyer, Tim; Rots, Marianne G.; Henning, Robert H.
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Functional Validation of the Putative Oncogenic Activity of PLAU
errBIOMEDICINES
IF3.9
err2022-12-30
err5
errOAAI
errSarno, Federica; Goubert, Desiree; Logie, Emilie; Rutten, Martijn G. S.; Koncz, Mihaly; Deben, Christophe; Niemarkt, Anita E.; Altucci, Lucia; Verschure, Pernette J.; Kiss, Antal; Vanden Berghe, Wim; Rots, Marianne G.
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RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis
errEMBO JOURNAL
IF8.3
err2021-09-17
err11
errOAAI
errTognoli, Maria Laura; Vlahov, Nikola; Steenbeek, Sander; Grawenda, Anna M.; Eyres, Michael; Cano-Rodriguez, David; Scrace, Simon; Kartsonaki, Christiana; von Kriegsheim, Alex; Willms, Eduard; Wood, Matthew J.; Rots, Marianne G.; van Rheenen, Jacco; O'Neill, Eric; Pankova, Daniela
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The Endothelium as a Target for Anti-Atherogenic Therapy: A Focus on the Epigenetic Enzymes EZH2 and SIRT1
errJOURNAL OF PERSONALIZED MEDICINE
IF3
err2021-02-05
err20
errOAAI
errFledderus, Jolien; Vanchin, Byambasuren; Rots, Marianne G.; Krenning, Guido
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Ubiquitin carboxyl-terminal hydrolase isozyme L1/UCHL1 suppresses epithelial-mesenchymal transition and is under-expressed in cadmium-transformed human bronchial epithelial cells
errCELL BIOLOGY AND TOXICOLOGY
IF5.9
err2020-10-10
err8
PREAI
errWu, Dan-Dan; Xu, Yan-Ming; Chen, De-Ju; Liang, Zhan-Ling; Chen, Xu-Li; Hylkema, Machteld N.; Rots, Marianne G.; Li, Sheng-Qing; Lau, Andy T. Y.
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Advances of epigenetic editing
errCURRENT OPINION IN CHEMICAL BIOLOGY
IF6.1
err2020-08-01
err64
errOAAI
errGjaltema, Rutger A. F.; Rots, Marianne G.
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Epigenetic Regulation of S100A9 and S100A12 Expression in Monocyte-Macrophage System in Hyperglycemic Conditions
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2020-06-02
err38
errOAAI
errMossel, Dieuwertje M.; Moganti, Kondaiah; Riabov, Vladimir; Weiss, Christel; Kopf, Stefan; Cordero, Julio; Dobreva, Gergana; Rots, Marianne G.; Klueter, Harald; Harmsen, Martin C.; Kzhyshkowska, Julia
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The timeline of epigenetic drug discovery: from reality to dreams
errCLINICAL EPIGENETICS
IF4.4
err2019-12-02
err243
errOAAI
errGanesan, A.; Arimondo, Paola B.; Rots, Marianne G.; Jeronimo, Carmen; Berdasco, Maria
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The influence of eukaryotic chromatin state on CRISPR-Cas9 editing efficiencies
errCURRENT OPINION IN BIOTECHNOLOGY
IF7
err2019-02-01
err107
errOAAI
errVerkuijl, Sebald A. N.; Rots, Marianne G.
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Importance of Metal-Ion Exchange for the Biological Activity of Coordination Complexes of the Biomimetic Ligand N4Py
errINORGANIC CHEMISTRY
IF4.7
err2018-06-19
err26
errOAAI
errGeersing, Arjan; Segaud, Nathalie; van der Wijst, Monique G. P.; Rots, Marianne G.; Roelfes, Gerard
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The past and presence of gene targeting: from chemicals and DNA via proteins to RNA
errPHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
IF4.7
err2018-04-23
err16
errOAAI
errGeel, T. M.; Ruiters, M. H. J.; Cool, R. H.; Halby, L.; Voshart, D. C.; Ruiz, L. Andrade; Niezen-Koning, K. E.; Arimondo, P. B.; Rots, M. G.
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The potential for targeted rewriting of epigenetic marks in COPD as a new therapeutic approach
errPHARMACOLOGY & THERAPEUTICS
IF12.5
err2018-02-01
err32
errOAAI
errWu, Dan-Dan; Song, Juan; Bartel, Sabine; Krauss-Etschmann, Susanne; Rots, Marianne G.; Hylkema, Machteld N.
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Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer's disease mice
errBRAIN
IF11.7
err2017-11-23
err131
errOAAI
errBustos, Fernando J.; Ampuero, Estibaliz; Jury, Nur; Aguilar, Rodrigo; Falahi, Fahimeh; Toledo, Jorge; Ahumada, Juan; Lata, Jaclyn; Cubillos, Paula; Henriquez, Berta; Guerra, Miguel V.; Stehberg, Jimmy; Neve, Rachael L.; Inestrosa, Nibaldo C.; Wyneken, Ursula; Fuenzalida, Marco; Hartel, Steffen; Sena-Esteves, Miguel; Varela-Nallar, Lorena; Rots, Marianne G.; Montecino, Martin; van Zundert, Brigitte
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Research Directions

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Co-authors
Cooperation Journals
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Dick de Zeeuw
H-index: 118 · Papers: 1.2K
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Rob Pieters
H-index: 104 · Papers: 909
G
Godefridus J. Peters
H-index: 103 · Papers: 1.4K
P
Peter Paul De Deyn
H-index: 102 · Papers: 2.1K
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