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RAS Pathway Inhibitors Combined with Targeted Agents Are Active in Patient-Derived Spheroids with Oncogenic KRAS Variants from Multiple Cancer Types Davoudi, Zahra; Dexheimer, Thomas S.; Coussens, Nathan P.; Silvers, Thomas; Fox, Raymond G.; Kemp, Samantha B.; Juneja, Poorva; Morris, Joel; Hollingshead, Melinda G.; Takebe, Naoko; Doroshow, James H.; Teicher, Beverly A. Share Save
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Combinatorial screen with apoptosis pathway targeted agents alrizomadlin, pelcitoclax, and dasminapant in multi-cell type tumor spheroids Coussens, Nathan P.; Dexheimer, Thomas S.; Silvers, Thomas; Sanchez, Phillip R.; Chen, Li; Hollingshead, Melinda G.; Takebe, Naoko; Doroshow, James H.; Teicher, Beverly A. Share Save
Combinatorial screen of targeted agents with the PI3K inhibitors inavolisib, alpelisib, duvelisib, and copanlisib in multi-cell type tumor spheroids Dexheimer, Thomas S.; Davoudi, Zahra; Coussens, Nathan P.; Silvers, Thomas; Morris, Joel; Takebe, Naoko; Said, Rabih; Moscow, Jeffrey A.; Doroshow, James H.; Teicher, Beverly A. Share Save
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Targeted Investigational Oncology Agents in the NCI-60: A Phenotypic Systems-based Resource Morris, Joel; Kunkel, Mark W.; White, Stephen L.; Wishka, Donn G.; Lopez, Omar D.; Bowles, Lori; Brady, Penny Sellers; Ramsey, Patricia; Grams, Julie; Rohrer, Tiffany; Martin, Karen; Dexheimer, Thomas S.; Coussens, Nathan P.; Evans, David; Risbood, Prabhakar; Sonkin, Dmitriy; Williams, John D.; Polley, Eric C.; Collins, Jerry M.; Doroshow, James H.; Teicher, Beverly A. Share Save
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Biochemical inhibition profiles of 370 wild type human kinases provide a basis for selecting alternative combinations of EGFR and VEGFR inhibitors Coussens, Nathan P.; Dexheimer, Thomas S.; Silvers, Thomas; Uzelac, Shannon; Georgius, Kyle; Carter, John; Shearer, Tia; Rao, Rekha; Gray, Karen; Srivastava, Apurva K.; Kinders, Robert J.; Evrard, Yvonne A.; Hollingshead, Melinda G.; Morris, Joel; Moscow, Jeffrey A.; Parchment, Ralph E.; Teicher, Beverly A.; Doroshow, James H. Share Save
Combination therapies in matched 3D in vitro and in vivo preclinical models of rare and recalcitrant cancers from the National Cancer Institute's Patient-Derived Models Repository Dexheimer, Thomas S.; Silvers, Thomas; Delosh, Rene; Reinhart, Russell; Ogle, Chad; Davoudi, Zahra; Jones, Eric; Trail, Debbie; Carter, John; Mills, Justine; Georgius, Kyle; Stotler, Howard; Norris, Michelle; Uzelac, Shannon; Borgel, Suzanne; Minor, Tiffanie; Stockwin, Luke; Mullendore, Michael; Plater, Kevin; Kalmbach, Keegan; Steed, Jessica; Murphy, Matthew; Bliss, Gareth; Bonomi, Carrie; Dougherty, Kelly; Gibson, Marion; Cooper, Kevin; Newton, Dianne; Timme, Cindy R.; Evrard, Yvonne A.; Hollingshead, Melinda G.; Coussens, Nathan P.; Parchment, Ralph E.; Doroshow, James H.; Teicher, Beverly A. Share Save
Advancing a screening platform with panels of patient-derived organoid models for drug discovery and development Rapisarda, Annamaria; Jones, Eric; Hose, Curtis; Harris, Erik; Campbell, Petreena S.; Ortiz, Mariaestela; Connelly, John; Mahashetty, Nanda; Silvers, Thomas; Davoudi, Zahra; Brady, Penny Sellers; Rohrer, Tiffany Nikirk; Grams, Julie; Martin, Karen; Ramsey, Patricia; Bowles, Lori; Britt, John R.; Parchment, Ralph E.; Dexheimer, Thomas S.; Teicher, Beverly A.; Doroshow, James H.; Coussens, Nathan P. Share Save
Targeted investigational oncology agents (IOA) in the NCI60: a phenotypic systems-based resource Morris, Joel; Kunkel, Mark W.; White, Stephen L.; Wishka, Donn G.; Lopez, Omar D.; Bowles, Lori; Sellers, Penny; Ramsey, Patricia; Grams, Julie; Rohrer, Tiffany; Martin, Karen; Dexheimer, Thomas; Sonkin, Dmitriy; Williams, John D.; Collins, Jerry M.; Doroshow, James H.; Teicher, Beverly A. Share Save
Aryl-hydrocarbon receptor inhibitors in combination with anticancer agents, especially proteasome pathway inhibitors, in a complex spheroid screen using patient-derived cell lines can result in greater-than additive cytotoxicity Teicher, Beverly A.; Moscow, Jeffrey A.; Morris, Joel; Doroshow, James H.; Dexheimer, Thomas S.; Coussens, Nathan P.; Silvers, Thomas; Delosh, Rene; Davoudi, Zahra; Reinhart, Russel; Ogle, Chad; Jones, Eric Share Save
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