logo
CanyamAI summaries for academic research
language
MobileMobile
  • Phone FeatureWeChat Mini Program
EnglishEnglish
noticeNotice
BlogBlog
delete
arrow
Back
W

William H. Gmeiner

Wake Forest University

29H-index
182Paper Count
3.3KCitation Count
Published Papers 54
Publication Date
logo
Activation of an adaptive antitumor immune response by the polymeric fluoropyrimidine CF10 involves TS/Top1 dual targeting
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2026-04-21
err0
errOAAI
errAkanksha Behl; Taylor M. Young; Xue Ma; Edward Cedrone; Marina A. Dobrovolskaia; John F. Whitesides; William H. Gmeiner
errShare
errSave
CF10 Displays Improved Synergy with Oxaliplatin in TP53-Null and Wild-Type CRC Cells from Increased Top1cc and Replication Stress
errCancers
IF4.4
err2026-03-09
err0
errOAAI
errTaylor M. Young; Rida Moumouni; Akanksha Behl; Upasana Das; William H. Gmeiner
errShare
errSave
LNP-Mediated CF10 Delivery Selectively Enhances Potency to Colorectal Cancer Cells and Preserves the TS/Top1 Dual Targeting Mechanism
errACS Applied Bio Materials
IF4.7
err2026-02-03
err0
PREAI
errSantu Sarkar; Akanksha Behl; William H. Gmeiner
errShare
errSave
Preclinical Evaluation of a Radiolabeled Anti-PSMA Dimeric Aptamer in a Murine Model of Human Prostate Cancer
errMolecules
IF4.6
err2026-01-31
err0
errOAAI
errAkesh Sinha; Darpan N. Pandya; Prabhakar Eeka; Olcay Boyacioglu; William H. Gmeiner; Thaddeus J. Wadas
errShare
errSave
The fluoropyrimidine polymer CF10 synergizes with 5-ethynyl-2′-deoxyuridine by promoting telomere attrition and mitotic catastrophe
errNAR MOLECULAR MEDICINE
IF0
err2026-01-01
err0
errOAAI
errDas, Upasana; Behl, Akanksha; Gmeiner, William H.
errShare
errSave
CF10 Displayed Improved Activity Relative to 5-FU in a Mouse CRLM Model Under Conditions of Physiological Folate
errCancers 2025, Vol. 17, Page 2739
IF4.4
err2025-08-23
err0
PREAI
errCharles Chidi Okechukwu; Xue Ma; Wencheng Li; Ralph D’Agostino, Jr.; Matthew G. Rees; Melissa M. Ronan; Jennifer A. Roth; William H. Gmeiner
errShare
errSave
The polymeric fluoropyrimidine CF10 overcomes limitations of 5-FU in pancreatic ductal adenocarcinoma cells through increased replication stress
errCANCER BIOLOGY & THERAPY
IF4.6
err2024-11-08
err0
errOAAI
errFinan, Jennifer M.; Di Niro, Roberto; Park, Soon Young; Jeong, Kang Jin; Hedberg, Madeline D.; Smith, Alexander; Mccarthy, Grace A.; Haber, Alex O.; Muschler, John; Sears, Rosalie C.; Mills, Gordon B.; Gmeiner, William H.; Brody, Jonathan R.
errShare
errSave
Review of Prodrug and Nanodelivery Strategies to Improve the Treatment of Colorectal Cancer with Fluoropyrimidine Drugs
errPHARMACEUTICS
IF5.5
err2024-05-29
err2
errOAAI
errSarkar, Santu; Kiren, Sezgin; Gmeiner, William H.
errShare
errSave
Role of O-GlcNAc conjugation and TS translational repression in 5-FU/LV resistance in CRC and CF10 response
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errOkechukwu, Charles C.; Ma, Xue; Gmeiner, William H.
errShare
errSave
A Novel Fluoropyrimidine Drug to Treat Recalcitrant Colorectal Cancer
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2023-06-01
err2
errOAAI
errSah, Naresh; Luna, Pamela; Mani, Chinnadurai; Gmeiner, William; Palle, Komaraiah
errShare
errSave
A novel second-generation nano-fluoropyrimidine to treat metastatic colorectal cancer and overcome 5-fluorouracil resistance
errCANCER RESEARCH
IF16.6
err2023-04-04
err1
PREAI
errSah, Naresh; Luna, Pamela; Mani, Chinnadurai; Gmeiner, William; Palle, Komaraiah
errShare
errSave
Improved Antitumor Activity of the Fluoropyrimidine Polymer CF10 in Preclinical Colorectal Cancer Models through Distinct Mechanistic and Pharmacologic Properties
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2021-03-02
err10
errOAAI
errGmeiner, William H.; Dominijanni, Anthony; Haber, Alex O.; Ghiraldeli, Lais P.; Caudell, David L.; D'Agostino, Ralph, Jr.; Pasche, Boris C.; Smith, Thomas L.; Deng, Zhiyong; Kiren, Sezgin; Mani, Chinnadurai; Palle, Komaraiah; Brody, Jonathan R.
errShare
errSave
AraC-FdUMP[10] Is a Next-Generation Fluoropyrimidine with Potent Antitumor Activity in PDAC and Synergy with PARG Inhibition
errMOLECULAR CANCER RESEARCH
IF4.7
err2021-02-16
err11
errOAAI
errHaber, Alex O.; Jain, Aditi; Mani, Chinnadurai; Nevler, Avinoam; Agostini, Lebaron C.; Golan, Talia; Palle, Komaraiah; Yeo, Charles J.; Gmeiner, William H.; Brody, Jonathan R.
errShare
errSave
Hairpin Oligonucleotide Can Functionalize Gold Nanorods for in Vivo Application Delivering Cytotoxic Nucleotides and Curcumin: A Comprehensive Study in Combination with Near-Infrared Laser
errACS OMEGA
IF4.3
err2020-11-02
err2
errOAAI
errDas, Upasana; Bhuniya, Avishek; Roy, Anup K.; Gmeiner, William H.; Ghosh, Supratim
errShare
errSave
F10 and 5-fluorouracil: Chemotherapeutic potential of F10 in alleviating colon cancer racial health disparity
errCANCER RESEARCH
IF16.6
err2020-08-15
err0
PREAI
errThaker, Shrey; Gmeiner, William H.; Ji, Ping; Zabaleta, Jovanny; Reyes, Tiana; DiGiovanni, Matthew; Wang, Xuefeng; Williams, Jennie L.
errShare
errSave
Chemistry of Fluorinated Pyrimidines in the Era of Personalized Medicine
errMOLECULES
IF4.6
err2020-07-29
err21
errOAAI
errGmeiner, William H.
errShare
errSave
Prexasertib treatment induces homologous recombination deficiency and synergizes with olaparib in triple-negative breast cancer cells
errBREAST CANCER RESEARCH
IF5.6
err2019-09-06
err55
errOAAI
errMani, Chinnadurai; Jonnalagadda, Shirisha; Lingareddy, Jojireddy; Awasthi, Sanjay; Gmeiner, William H.; Palle, Komaraiah
errShare
errSave
Enhanced potency of the polymeric fluoropyrimidine CF10 to KRAS-mutant colorectal cancer cells
errCANCER RESEARCH
IF16.6
err2019-07-01
err0
PREAI
errGmeiner, William H.; Manandhar, Mandira; Hinds, Amanda M.; Holmes, Julija; Vidi, Pierre; Tsunoda, Toshiyuki; Shirasawa, Senji
errShare
errSave
Mechanistic studies reveal novel molecular insights on anticancer properties of F10 compound in human colon cancer cells
errCANCER RESEARCH
IF16.6
err2019-07-01
err0
PREAI
errMani, Chinnadurai; Gmeiner, William; Palle, Komaraiah
errShare
errSave
Development of a Colorectal Cancer 3D Micro-tumor Construct Platform From Cell Lines and Patient Tumor Biospecimens for Standard-of-Care and Experimental Drug Screening
errANNALS OF BIOMEDICAL ENGINEERING
IF5.4
err2019-04-24
err29
errOAAI
errForsythe, Steven; Mehta, Naren; Devarasetty, Mahesh; Sivakumar, Hemamylammal; Gmeiner, William; Soker, Shay; Votanopoulos, Konstantinos; Skardal, Aleksander
errShare
errSave

Research Directions

The data has not been retrieved yet.
Co-authors
Cooperation Journals
R
Ralph B. D’Agostino
H-index: 236 · Papers: 2.0K
G
Gordon B. Mills
H-index: 231 · Papers: 3.5K

Yves Pommier
H-index: 138 · Papers: 2.0K
C
Charles J. Yeo
H-index: 132 · Papers: 958
S
Shay Söker
H-index: 85 · Papers: 395
View more