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SaveIdentification of JNJ-61803534, a RORγt Inverse Agonist for the Treatment of Psoriasis
Kinzel, Olaf; Goldberg, Steven D.; Cummings, Maxwell D.; Gege, Christian; Steeneck, Christoph; Xue, Xiaohua; Albers, Michael; Schluter, Thomas; Kleymann, Gerald; Scott, Brian; Sepassi, Kia; Schoetens, Freddy; Venkatesan, Hariharan; Tanis, Virginia M.; Coe, Kevin; Sales, Zachary S.; Spurlino, John; Milligan, Cynthia; Fourie, Anne M.; Edwards, James P.; Hoffmann, Thomas
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SaveSynthesis and Characterization of DHODH Inhibitors Based on the Vidofludimus Scaffold with Pronounced Anti-SARS-CoV-2 Activity
Gege, Christian; Hahn, Friedrich; Wangen, Christina; Haege, Sigrun; Herrmann, Alexandra; Uhlig, Nadja; Eberlein, Valentina; Issmail, Leila; Klopfleisch, Robert; Grunwald, Thomas; Marschall, Manfred; Kohlhof, Hella; Vitt, Daniel
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SaveDevelopment of a Potent Nurr1 Agonist Tool for In Vivo Applications
Vietor, Jan; Gege, Christian; Stiller, Tanja; Busch, Romy; Schallmayer, Espen; Kohlhof, Hella; Hoefner, Georg; Pabel, Joerg; Marschner, Julian A.; Merk, Daniel
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SaveA helicase-primase drug candidate with sufficient target tissue exposure affects latent neural herpes simplex virus infections
Gege, Christian; Bravo, Fernando J.; Uhlig, Nadja; Hagmaier, Timo; Schmachtenberg, Rosanne; Elis, Julia; Burger-Kentischer, Anke; Finkelmeier, Doris; Hamprecht, Klaus; Grunwald, Thomas; Bernstein, David, I; Kleymann, Gerald
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SaveIdentification of a potent, orally bioavailable and selective MCT4 Inhibitor for the treatment of solid Warburg tumors
Hambruch, Nina; Herkert, Barbara; Gege, Christian; Mallinger, Aurelie; Fabian, Johannes; Kinzel, Olaf; Wang, Yansong; Fink, Gero; Albers, Michael; Funk, Anette; Bittman-Waetzig, Annika; Fleckenstein, Tilly; Braun, Floriane; Kremoser, Claus
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SaveHow to develop a differentiated FXR agonist: GS-9674 shows a reduced side effect profile in mice, monkeys amd human phase I studies compared to its predecessor Px-102
Hambruch, Eva; Hollenback, David; Liles, John; Kinzel, Olaf; Birkel, Manfred; Fink, Gero; French, Dorothy; Gege, Christian; Hornberger, Martin; Watkins, William; Kremoser, Claus
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