Not logged in SAFETY OF ONC201 TREATMENT IN PATIENTS WITH PREVIOUSLY TREATED H3 K27M-MUTANT GLIOMA: RESULTS FROM ONC028, AN ONGOING COMPASSIONATE USE PROGRAM Sharma, Akansha; Aiken, Robert; Korones, David N.; Koschmann, Carl; Lubes, Jourdan; Gardner, Sharon L.; Morrison, Marion; Ramage, Samuel C.; Tarapore, Rohinton S.; Odia, Yazmin Share Save
Safety and pharmacokinetics of ONC201 (dordaviprone) administered two consecutive days per week in pediatric patients with H3 K27M-mutant glioma Odia, Yazmin; Koschmann, Carl; Vitanza, Nicholas A.; de Blank, Peter; Aguilera, Dolly; Allen, Jeffrey; Daghistani, Doured; Hall, Matthew; Khatib, Ziad; Kline, Cassie; Macdonald, Tobey; Mueller, Sabine; Faison, Shamia L.; Allen, Joshua E.; Naderer, Odin J.; Ramage, Samuel C.; Tarapore, Rohinton S.; Mcgovern, Susan Lynne; Khatua, Soumen; Zaky, Wafik; Gardner, Sharon L. Share Save
ACTION: a randomized phase 3 study of ONC201 (dordaviprone) in patients with newly diagnosed H3 K27M-mutant diffuse glioma Arrillaga-Romany, Isabel; Lassman, Andrew; Mcgovern, Susan L.; Mueller, Sabine; Nabors, Burt; van den Bent, Martin; Vogelbaum, Michael A.; Allen, Joshua E.; Melemed, Allen S.; Tarapore, Rohinton S.; Wen, Patrick Y.; Cloughesy, Timothy Share Save
Selective DRD2 antagonist and ClpP agonist ONC201 in a recurrent non-midline H3 K27M-mutant glioma cohort Odia, Yazmin; Hall, Matthew D.; Cloughesy, Timothy Francis; Wen, Patrick Y.; Arrillaga-Romany, Isabel; Daghistani, Doured; Mehta, Minesh P.; Tarapore, Rohinton S.; Ramage, Samuel C.; Allen, Joshua E. Share Save
ACTION: A RANDOMIZED PHASE 3 STUDY OF DORDAVIPRONE (ONC201) IN PATIENTS WITH NEWLY DIAGNOSED H3 K27M-MUTANT DIFFUSE GLIOMA Arrillaga-Romany, I.; Lassman, A.; McGovern, S. L.; Mueller, S.; Nabors, L. B.; van den Bent, M.; Vogelbaum, M.; Allen, J. E.; Melemed, A. S.; Tarapore, R.; Wen, P. Y.; Cloughsey, T. Share Save
Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways Venneti, Sriram; Kawakibi, Abed Rahman; Ji, Sunjong; Waszak, Sebastian M.; Sweha, Stefan R.; Mota, Mateus; Pun, Matthew; Deogharkar, Akash; Chung, Chan; Tarapore, Rohinton S.; Ramage, Samuel; Chi, Andrew; Wen, Patrick Y.; Arrillaga-Romany, Isabel; Batchelor, Tracy T.; Butowski, Nicholas A.; Sumrall, Ashley; Shonka, Nicole; Harrison, Rebecca A.; De Groot, John; Mehta, Minesh; Hall, Matthew D.; Daghistani, Doured; Cloughesy, Timothy F.; Ellingson, Benjamin M.; Beccaria, Kevin; Varlet, Pascale; Kim, Michelle M.; Umemura, Yoshie; Garton, Hugh; Franson, Andrea; Schwartz, Jonathan; Jain, Rajan; Kachman, Maureen; Baum, Heidi; Burant, Charles F.; Mottl, Sophie L.; Cartaxo, Rodrigo T.; John, Vishal; Messinger, Dana; Qin, Tingting; Peterson, Erik; Sajjakulnukit, Peter; Ravi, Karthik; Waugh, Alyssa; Walling, Dustin; Ding, Yujie; Xia, Ziyun; Schwendeman, Anna; Hawes, Debra; Yang, Fusheng; Judkins, Alexander R.; Wahl, Daniel; Lyssiotis, Costas A.; de la Nava, Daniel; Alonso, Marta M.; Eze, Augustine; Spitzer, Jasper; Schmidt, Susanne V.; Duchatel, Ryan J.; Dun, Matthew D.; Cain, Jason E.; Jiang, Li; Stopka, Sylwia A.; Baquer, Gerard; Regan, Michael S.; Filbin, Mariella G.; Agar, Nathalie Y. R.; Zhao, Lili; Kumar-Sinha, Chandan; Mody, Rajen; Chinnaiyan, Arul; Kurokawa, Ryo; Pratt, Drew; Yadav, Viveka N.; Grill, Jacques; Kline, Cassie; Mueller, Sabine; Resnick, Adam; Nazarian, Javad; Allen, Joshua E.; Odia, Yazmin; Gardner, Sharon L.; Koschmann, Carl Share Save
ACTION: A randomized phase 3 study of dordaviprone (ONC201) in patients with newly diagnosed H3 K27M-mutant diffuse glioma Arrillaga-Romany, Isabel; Lassman, Andrew; McGovern, Susan L.; Mueller, Sabine; Nabors, Louis B.; Van den Bent, Martin; Vogelbaum, Michael; Allen, Joshua E.; Melemed, Allen S.; Tarapore, Rohinton S.; Yang, Dewen; Wen, Patrick; Cloughsey, Timothy Share Save
Phase I dose escalation and expansion trial of single agent ONC201 in pediatric diffuse midline gliomas following radiotherapy Gardner, Sharon L.; Tarapore, Rohinton S.; Allen, Jeffrey; McGovern, Susan L.; Zaky, Wafik; Odia, Yazmin; Daghistani, Doured; Diaz, Zuanel; Hall, Matthew D.; Khatib, Ziad; Koschmann, Carl; Cantor, Evan; Kurokawa, Ryo; MacDonald, Tobey J.; Aguilera, Dolly; Vitanza, Nicholas A.; Mueller, Sabine; Kline, Cassie; Lu, Guangrong; Allen, Joshua E.; Khatua, Soumen Share Save
Erratum. Foxo1 Inhibits Diabetic Mucosal Wound Healing but Enhances Healing of Normoglycemic Wounds. (vol 64, pg 243, 2015) Xu, Fanxing; Othman, Badr; Lim, Jason; Batres, Angelika; Ponugoti, Bhaskar; Zhang, Chenying; Yi, Leah; Liu, Jian; Tian, Chen; Hameedaldeen, Alhassan; Alsadun, Sarah; Tarapore, Rohinton; Graves, Dana T. Share Save
Serial H3K27M cell-free tumor DNA (cf-tDNA) tracking predicts ONC201 treatment response and progression in diffuse midline glioma Cantor, Evan; Wierzbicki, Kyle; Tarapore, Rohinton S.; Ravi, Karthik; Thomas, Chase; Cartaxo, Rodrigo; Yadav, Viveka Nand; Ravindran, Ramya; Bruzek, Amy K.; Wadden, Jack; John, Vishal; Babila, Clarissa May; Cummings, Jessica R.; Kawakibi, Abed Rahman; Ji, Sunjong; Ramos, Johanna; Paul, Alyssa; Walling, Dustin; Leonard, Marcia; Robertson, Patricia; Franson, Andrea; Mody, Rajen; Garton, Hugh J. L.; Venetti, Sriram; Odia, Yazmin; Kline, Cassie; Vitanza, Nicholas A.; Khatua, Soumen; Mueller, Sabine; Allen, Joshua E.; Gardner, Sharon L.; Koschmann, Carl Share Save
SERIAL PLASMA AND CSF CELL-FREE TUMOR DNA (CF-TDNA) TRACKING IN DIFFUSE MIDLINE GLIOMA PATIENTS UNDERGOING TREATMENT WITH ONC201 Cantor, Evan; Wierzbicki, Kyle; Tarapore, Rohinton S.; Thomas, Chase; Cartaxo, Rodrigo; Yadav, Viveka Nand; Bruzek, Amy K.; Wadden, Jack; Babilla, Clarissa May; Kawakibi, Abed Rhaman; Ji, Sunjong; Ramos, Johanna; Paul, Alyssa; Wolfe, Ian; Leonard, Marcia; Robertson, Partricia; Franson, Andrea; Mody, Rajen; Garton, Hugh; Odia, Yazmin; Kline, Cassie; Vitanza, Nicholas A.; Khatua, Soumen; Mueller, Sabine; Allen, Joshua E.; Gardner, Sharon; Koschmann, Carl Share Save
Modulating the unfolded protein response with ONC201 to impact on radiation response in prostate cancer cells Amoroso, Francesca; Glass, Kimberley; Singh, Reema; Liberal, Francisco; Steele, Rebecca E.; Maguire, Sarah; Tarapore, Rohinton; Allen, Joshua E.; Van Schaeybroeck, Sandra; Butterworth, Karl T.; Prise, Kevin; O'Sullivan, Joe M.; Jain, Suneil; Waugh, David J.; Mills, Ian G. Share Save
ONC201 Shows Potent Anticancer Activity Against Medullary Thyroid Cancer via Transcriptional Inhibition of RET, VEGFR2, and IGFBP2 Bagheri-Yarmand, Rozita; Dadu, Ramona; Ye, Lei; Jebaraj, Yaashmin Shiny; Martinez, Jade A.; Ma, Junsheng; Tarapore, Rohinton S.; Allen, Joshua E.; Sherman, Steven, I; Williams, Michelle D.; Gagel, Robert F. Share Save
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Immunomodulatory activity of selective DRD2 antagonist ONC201, an imipridone, in metastatic endometrial cancer (mEC) Tarapore, Rohinton S.; Prabhu, Varun V.; Mok, Samuel C.; Yeung, Chilam Au; Rodriguez, Lorna; Girda, Eugenia; Mantia-Smaldone, Gina; Bae-Jump, Victoria; Lu, Guangrong; Oster, Wolfgang; Allen, Joshua E. Share Save
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Biological activity of weekly ONC201 in adult recurrent glioblastoma patients Arrillaga-Romany, Isabel; Odia, Yazmin; Prabhu, Varun V.; Tarapore, Rohinton S.; Merdinger, Krystal; Stogniew, Martin; Oster, Wolfgang; Allen, Joshua E.; Mehta, Minesh; Batchelor, Tracy T.; Wen, Patrick Y. Share Save
Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201 Chi, Andrew S.; Tarapore, Rohinton S.; Hall, Matthew D.; Shonka, Nicole; Gardner, Sharon; Umemura, Yoshie; Sumrall, Ashley; Khatib, Ziad; Mueller, Sabine; Kline, Cassie; Zaky, Wafik; Khatua, Soumen; Weathers, Shiao-Pei; Odia, Yazmin; Niazi, Toba N.; Daghistani, Doured; Cherrick, Irene; Korones, David; Karajannis, Matthias A.; Kong, Xiao-Tang; Minturn, Jane; Waanders, Angela; Arillaga-Romany, Isabel; Batchelor, Tracy; Wen, Patrick Y.; Merdinger, Krystal; Schalop, Lee; Stogniew, Martin; Allen, Joshua E.; Oster, Wolfgang; Mehta, Minesh P. Share Save
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