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Local delivery of cell surface-targeted immunocytokines programs systemic antitumor immunity Santollani, Luciano; Maiorino, Laura; Zhang, Yiming J.; Palmeri, Joseph R.; Stinson, Jordan A.; Duhamel, Lauren R.; Qureshi, Kashif; Suggs, Jack R.; Porth, Owen T.; Pinney, William; Al Msari, Riyam; Walsh, Agnes A.; Wittrup, K. Dane; Irvine, Darrell J. Share Save
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Overcoming lung cancer immunotherapy resistance by combining nontoxic variants of IL-12 and IL-2 Horton, Brendan L.; DSouza, Alicia D.; Zagorulya, Maria; McCreery, Chloe, V; Abhiraman, Gita C.; Picton, Lora; Sheen, Allison; Agarwal, Yash; Momin, Noor; Wittrup, K. Dane; White, Forest M.; Garcia, K. Christopher; Spranger, Stefani Share Save
Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer Schmidt, Daniel R.; Gramatikov, Iva Monique T.; Sheen, Allison; Williams, Christopher L.; Hurwitz, Martina; Dodge, Laura E.; Holupka, Edward; Kiger, W. S., III; Cornwall-Brady, Milton R.; Huang, Wei; Mak, Howard H.; Cormier, Kathleen S.; Condon, Charlene; Dane Wittrup, K. D.; Yilmaz, Omer H.; Stevenson, Mary Ann; Down, Julian D.; Floyd, Scott R.; Roper, Jatin; Vander Heiden, Matthew G. Share Save
Both intratumoral regulatory T cell depletion and CTLA-4 antagonism are required for maximum efficacy of anti- CTLA-4 antibodies Lax, Brianna M.; Palmeri, Joseph R.; Lutz, Emi A.; Sheen, Allison; Stinson, Jordan A.; Duhamel, Lauren; Santollani, Luciano; Kennedy, Alan; Rothschilds, Adrienne M.; Spranger, Stefani; Sansom, David M.; Wittrup, K. Dane Share Save
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Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer Zagorulya, Maria; Yim, Leon; Morgan, Duncan M.; Edwards, Austin; Torres-Mejia, Elen; Momin, Noor; McCreery, Chloe V.; Zamora, Izabella L.; Horton, Brendan L.; Fox, James G.; Wittrup, K. Dane; Love, J. Christopher; Spranger, Stefani Share Save
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Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies Lutz, Emi A.; Agarwal, Yash; Momin, Noor; Cowles, Sarah C.; Palmeri, Joseph R.; Duong, Ellen; Hornet, Vladlena; Sheen, Allison; Lax, Brianna M.; Rothschilds, Adrienne M.; Irvine, Darrell J.; Spranger, Stefani; Wittrup, K. Dane Share Save
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Identification of Highly Cross-Reactive Mimotopes for a Public T Cell Response in Murine Melanoma Grace, Beth E.; Backlund, Coralie M.; Morgan, Duncan M.; Kang, Byong H.; Singh, Nishant K.; Huisman, Brooke D.; Rappazzo, C. Garrett; Moynihan, Kelly D.; Maiorino, Laura; Dobson, Connor S.; Kyung, Taeyoon; Gordon, Khloe S.; Holec, Patrick, V; Mbah, Overbeck C. Takou; Garafola, Daniel; Wu, Shengwei; Love, J. Christopher; Wittrup, K. Dane; Irvine, Darrell J.; Birnbaum, Michael E. Share Save
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Combination of αPD-1 and extended half-life IL-2 is effective against the GL261 glioma and uniquely reverses GBM-associated immunosuppression Tritz, Zachariah Peter; Ayasoufi, Katayoun; Malo, Courtney Sarah; Himes, Benjamin; Zastrow, Alexi; Wolf, Delaney; Goddery, Emma; Khadka, Roman; Fain, Cori; Chen, Maggie; Yokanovich, Lila T.; Jin, Fang; Hansen, Michael; Wang, Chensu; Moynihan, Kelly; Irvine, Darrell J.; Wittrup, K. Dane; Parney, Ian F.; Johnson, Aaron J. Share Save
Co-Anchoring of Engineered Immunogen and Immunostimulatory Cytokines to Alum Promotes Enhanced-Humoral Immunity Chang, Jason Y. H.; Agarwal, Yash; Rodrigues, Kristen A.; Momin, Noor; Ni, Kaiyuan; Read, Benjamin J.; Moyer, Tyson J.; Mehta, Naveen K.; Silva, Murillo; Suh, Heikyung; Melo, Mariane B.; Wittrup, K. Dane; Irvine, Darrell J. Share Save
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