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Laura Evgin

University of British Columbia

21H-index
101Paper Count
2.3KCitation Count
Published Papers 31
Publication Date
Engagement of the TCR against an oncolytic virus generates a population of effector CAR T cells with potent antitumor activity
err2026-06-05
err0
errOAAI
errOlivia Liseth; Elizabeth Appleton; Benjamin Kendall; Jill Thompson; Thanich Sangsuwannukul; Jason Tonne; Rosa Maria Diaz; Laura Evgin; Anton Patrikeev; Nicolas Sarbia; Shane Foo; Kevin Harrington; Masahiro Ono; Alan Melcher; Richard Vile
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Ionizing radiation enhances CAR T-cell infiltration and efficacy in solid tumors
err2026-04-15
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errOAAI
errLZ Lisa Zhan; MA Meredith A. Clark; PL Pauline Loos; CL Che-Min Lee; LE Laura E. R. Paulus; RS Rocky Shi; PK Prabhreet K. Sekhon; JM James M. Piret; LE Laura Evgin †; KL Kevin L. Bennewith †
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Using oncolytic viruses to exploit endogenous TCR signaling for modulation of CAR T phenotype and function against solid tumors
err2025-11-01
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PREAI
errLiseth, Olivia; Appleton, Elizabeth; Thompson, Jill; Kendall, Luke; Evgin, Laura; Ono, Masahiro; Melcher, Alan; Vile, Richard
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The progressively exhausted T cell response to a poorly immunogenic model of HCC can be partially rescued by immune checkpoint blockade and is heavily suppressed by T cell responses to oncolytic virotherapy
err2025-09-01
err0
PREAI
errThanich Sangsuwannukul; Benjamin Kendall; Jason Tonne; Olivia Liseth; Jill Thompson; Kamonlapat Supimon; Muriel M. Metko; Alex Chen; Maria P. Chiriboga Yerovi; Rosa Maria Diaz; Laura Evgin; Mason J. Webb; Jacob van Vloten; Satdarshan P. Monga; Sheeba Irshad; Mark McNiven; Lewis Roberts; Richard G. Vile
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Somatic IRF4 mutations and thymic tropism in primary mediastinal large B-cell lymphoma
errBlood
IF23.1
err2025-06-24
err0
errOAAI
errShinya Rai; Gerben Duns; Fabian Frontzek; Jasper C. H. Wong; Yifan Yin; Michael Yu Li; Makoto Kishida; Manabu Fujisawa; Shannon Healy; Elena Viganò; Aixiang Jiang; Bruce Woolcock; Adèle Telenius; Susana Ben-Neriah; Barbara Meissner; Merrill Boyle; Hisae Nakamura; Luke O’Brien; Claudia Cassidy; Andrew Lytle; Pedro Farinha; Graham Slack; Laura K. Hilton; Ryan D. Morin; Leandro Venturutti; Tomohiro Aoki; Nicole Wretham; Jonathan W. Bush; Laura Evgin; Kerry J. Savage; David W. Scott; Christian Steidl
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Expression of tumor antigens within an oncolytic virus enhances the anti-tumor T cell response
err2024-06-27
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errOAAI
errWebb, Mason J.; Sangsuwannukul, Thanich; van Vloten, Jacob; Evgin, Laura; Kendall, Benjamin; Tonne, Jason; Thompson, Jill; Metko, Muriel; Moore, Madelyn; Yerovi, Maria P. Chiriboga; Olin, Michael; Borgatti, Antonella; McNiven, Mark; Monga, Satdarshan P. S.; Borad, Mitesh J.; Melcher, Alan; Roberts, Lewis R.; Vile, Richard
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Direct in vivo CAR T cell engineering
err2024-05-01
err10
errOAAI
errShort, Lauralie; Holt, Robert A.; Cullis, Pieter R.; Evgin, Laura
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Oncolytic virus-mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice
err2022-04-13
err111
errOAAI
errEvgin, Laura; Kottke, Tim; Tonne, Jason; Thompson, Jill; Huff, Amanda L.; van Vloten, Jacob; Moore, Madelyn; Michael, Josefine; Driscoll, Christopher; Pulido, Jose; Swanson, Eric; Kennedy, Richard; Coffey, Matt; Loghmani, Houra; Sanchez-Perez, Luis; Olivier, Gloria; Harrington, Kevin; Pandha, Hardev; Melcher, Alan; Diaz, Rosa Maria; Vile, Richard G.
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Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy
err2021-03-26
err9
errOAAI
errKottke, Timothy; Tonne, Jason; Evgin, Laura; Driscoll, Christopher B.; van Vloten, Jacob; Jennings, Victoria A.; Huff, Amanda L.; Zell, Brady; Thompson, Jill M.; Wongthida, Phonphimon; Pulido, Jose; Schuelke, Matthew R.; Samson, Adel; Selby, Peter; Ilett, Elizabeth; McNiven, Mark; Roberts, Lewis R.; Borad, Mitesh J.; Pandha, Hardev; Harrington, Kevin; Melcher, Alan; Vile, Richard G.
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Vesicular Stomatitis Virus Encoding a Destabilized Tumor Antigen Improves Activation of Anti-tumor T Cell Responses
err2020-12-01
err3
errOAAI
errHuff, Amanda L.; Evgin, Laura; Thompson, Jill; Kottke, Tim; Driscoll, Christopher B.; Tonne, Jason; Wongthida, Phonphimon; Schuelke, Matthew; Shim, Kevin G.; Mer, Georges; Ramirez-Alvarado, Marina; Vile, Richard
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Brain cancer induces systemic immunosuppression through release of non-steroid soluble mediators
errBRAIN
IF11.7
err2020-11-30
err54
errOAAI
errAyasoufi, Katayoun; Pfaller, Christian K.; Evgin, Laura; Khadka, Roman H.; Tritz, Zachariah P.; Goddery, Emma N.; Fain, Cori E.; Yokanovich, Lila T.; Himes, Benjamin T.; Jin, Fang; Zheng, Jiaying; Schuelke, Matthew R.; Hansen, Michael J.; Tung, Wesley; Parney, Ian F.; Pease, Larry R.; Vile, Richard G.; Johnson, Aaron J.
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Oncolytic virus-derived type I interferon restricts CAR T cell therapy
err2020-06-24
err85
errOAAI
errEvgin, Laura; Huff, Amanda L.; Wongthida, Phonphimon; Thompson, Jill; Kottke, Tim; Tonne, Jason; Schuelke, Matthew; Ayasoufi, Katayoun; Driscoll, Christopher B.; Shim, Kevin G.; Reynolds, Pierce; Monie, Dileep D.; Johnson, Aaron J.; Coffey, Matt; Young, Sarah L.; Archer, Gary; Sampson, John; Pulido, Jose; Perez, Luis Sanchez; Vile, Richard
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Ad-CD40L mobilizes CD4 T cells for the treatment of brainstem tumors
err2020-05-27
err11
errOAAI
errWongthida, Phonphimon; Schuelke, Matthew R.; Driscoll, Christopher B.; Kottke, Timothy; Thompson, Jill M.; Tonne, Jason; Stone, Cathy; Huff, Amanda L.; Wetmore, Cynthia; Davies, James A.; Parker, Alan L.; Evgin, Laura; Vile, Richard G.
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Generation of a Tumor-Specific Chemokine Gradient Using Oncolytic Vesicular Stomatitis Virus Encoding CXCL9
err2020-03-01
err32
errOAAI
errEckert, Elizabeth C.; Nace, Rebecca A.; Tonne, Jason M.; Evgin, Laura; Vile, Richard G.; Russell, Stephen J.
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APOBEC3B-mediated corruption of the tumor cell immunopeptidome induces heteroclitic neoepitopes for cancer immunotherapy
err2020-02-07
err51
errOAAI
errDriscoll, Christopher B.; Schuelke, Matthew R.; Kottke, Timothy; Thompson, Jill M.; Wongthida, Phonphimon; Tonne, Jason M.; Huff, Amanda L.; Miller, Amber; Shim, Kevin G.; Molan, Amy; Wetmore, Cynthia; Selby, Peter; Samson, Adel; Harrington, Kevin; Pandha, Hardev; Melcher, Alan; Pulido, Jose S.; Harris, Reuben; Evgin, Laura; Vile, Richard G.
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Diverse immunotherapies can effectively treat syngeneic brainstem tumors in the absence of overt toxicity
err2019-07-17
err13
errOAAI
errSchuelke, Matthew R.; Wongthida, Phonphimon; Thompson, Jill; Kottke, Timothy; Driscoll, Christopher B.; Huff, Amanda L.; Shim, Kevin G.; Coffey, Matt; Pulido, Jose; Evgin, Laura; Vile, Richard G.
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APOBEC3 Mediates Resistance to Oncolytic Viral Therapy
err2018-12-01
err20
errOAAI
errHuff, Amanda L.; Wongthida, Phonphimon; Kottke, Timothy; Thompson, Jill M.; Driscoll, Christopher B.; Schuelke, Matthew; Shim, Kevin G.; Harris, Reuben S.; Molan, Amy; Pulido, Jose S.; Selby, Peter J.; Harrington, Kevin J.; Melcher, Alan; Evgin, Laura; Vile, Richard G.
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Ad5NULL-A20: A Tropism-Modified, αvβ6 Integrin-Selective Oncolytic Adenovirus for Epithelial Ovarian Cancer Therapies
err2018-09-04
err39
errOAAI
errUusi-Kerttula, Hanni; Davies, James A.; Thompson, Jill M.; Wongthida, Phonphimon; Evgin, Laura; Shim, Kevin G.; Bradshaw, Angela; Baker, Alexander T.; Rizkallah, Pierre J.; Jones, Rachel; Hanna, Louise; Hudson, Emma; Vile, Richard G.; Chester, John D.; Parker, Alan L.
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White paper on microbial anti-cancer therapy and prevention
err2018-08-06
err115
errOAAI
errForbes, Neil S.; Coffin, Robert S.; Deng, Liang; Evgin, Laura; Fiering, Steve; Giacalone, Matthew; Gravekamp, Claudia; Gulley, James L.; Gunn, Hal; Hoffman, Robert M.; Kaur, Balveen; Liu, Ke; Lyerly, Herbert Kim; Marciscano, Ariel E.; Moradian, Eddie; Ruppel, Sheryl; Saltzman, Daniel A.; Tattersall, Peter J.; Thorne, Steve; Vile, Richard G.; Zhang, Halle Huihong; Zhou, Shibin; McFadden, Grant
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