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M

Marko Hyvönen

university of cambridge

41H-index
204Paper Count
6.2KCitation Count
Published Papers 76
Publication Date
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Exploiting PKM2-PARP1 dependency: Isoselenazolium-olaparib conjugates achieve multimodal PKM2 suppression
errBioorganic Chemistry
IF4.7
err2026-05-09
err0
PREAI
errPavels Dimitrijevs; Marina Makrecka-Kuka; Diana Zelencova-Gopejenko; Zhanna Rudevica; Ksenija Korotkaja; Anna Zajakina; Kristofers Rudzitis; Agnieszka Bogucka; Marko Hyvönen; Teodors Pantelejevs; Pavel Arsenyan
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Towards the targeted protein degradation of CK2: design and synthesis of CAM4066-based PROTACs
errBeilstein Journal of Organic Chemistry
IF2.1
err2026-04-22
err0
errOAAI
errDay-Riley, Sophie; Krajcovicova, Sona; Sokhal, Aryaman Raj; Venne, Jan L.; Brear, Paul; Hyvonen, Marko; Whitehurst, Benjamin C.; Carroll, Jason S.; Spring, David R.
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Yeast Display Technology Enables Rapid Discovery of Low-Nanomolar Macrocyclic Peptide Inhibitors of Human Angiotensin-Converting Enzyme 2
errJournal of Medicinal Chemistry
IF6.8
err2026-03-24
err0
errOAAI
errZhanna Romanyuk; Giacomo Bettin; Paul Brear; Sara Linciano; Ylenia Mazzocato; Simone Bonadies; Ilaria Zanotto; Camilla Mazzucco; Alan Monferone; Miguel A. Soler; Gianfranco Pasut; Sara De Martin; Alessandro Scarso; Christian Heinis; Sylvia Rothenberger; Marko Hyvönen; Alessandro Angelini
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Utilizing Constrained Bicyclic Peptides for In Vitro Diagnostics
errACS Nano
IF16
err2026-02-13
err0
errOAAI
errAndré Shamsabadi; Adam Creamer; Christy J. Sadler; Aida Abdelwahed; Katherine U. Gaynor; Yuliya Demydchuk; Gabriela Ivanova-Berndt; Katerine Van Rietschoten; Paul Beswick; Liuhong Chen; Gustavo Arruda Bezerra; Aleksei Lulla; Paul Brear; Marko Hyvönen; Michael J. Skynner; Molly M. Stevens
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Exploiting the Cryptic αD Pocket of Casein Kinase 2α (CK2α) to Deliver Highly Potent and Selective Type 1 Inhibitors
errJournal of Medicinal Chemistry
IF6.8
err2025-10-14
err0
errOAAI
errPaul A. Glossop; Paul Brear; Susanne Wright; Neil Flanagan; Melanie S. Glossop; Charlotte A. L. Lane; Richard P. Butt; David R. Spring; Marko Hyvönen; Darren Cawkill
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Tumour-specific STING agonist synthesis via a two-component prodrug system
errNature Chemistry
IF20.2
err2025-09-16
err0
errOAAI
errNai-Shu Hsu; Cong Tang; Raquel V. Mendes; Carlos Labão-Almeida; Caio V. dos Reis; Ana R. Coelho; Marta C. Marques; Mar Cabeza Cabrerizo; Roman Misteli; Timothy P. C. Rooney; Marko Hyvönen; Francisco Corzana; Rita Fior; Gonçalo J. L. Bernardes
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Potent Fluorescent Probe for Target-Engagement Studies of Allosteric Pyruvate Kinase Modulators
errAngewandte Chemie International Edition
IF0
err2025-08-29
err0
errOAAI
errOscar Nilsson; Anna P. Valaka; Dr. Liliana Håversen; Dr. Agnieszka Bogucka; Dr. István Köteles; Dr. Paul Brear; Dr. Mikael Rutberg; Dr. Anders Gunnarsson; Prof. Marko Hyvönen; Prof. Morten Grøtli
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Fluorescent binding assay for allosteric ligands of liver pyruvate kinase
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-07-25
err0
errOAAI
errOscar Nilsson; Agnieszka Bogucka; István Köteles; Liliana Håversen; Sara Liljenberg; Mikael Rutberg; Marko Hyvönen; Morten Grøtli
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Development of novel ELISAs for total GDF-15 and H-specific GDF-15
errCLINICAL CHEMISTRY
IF6.3
err2024-10-02
err0
PREAI
errKalra, B.; Parekh, H.; Patel, A. S.; Mistry, S.; Hyvonen, M.; Kumar, A.
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Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-08-27
err0
errOAAI
errStockwell, Simon R.; Scott, Duncan E.; Fischer, Gerhard; Guarino, Estrella; Rooney, Timothy P. C.; Feng, Tzu-Shean; Moschetti, Tommaso; Srinivasan, Rajavel; Alza, Esther; Asteian, Alice; Dagostin, Claudio; Alcaide, Anna; Rocaboy, Mathieu; Blaszczyk, Beata; Higueruelo, Alicia; Wang, Xuelu; Rossmann, Maxim; Perrior, Trevor R.; Blundell, Tom L.; Spring, David R.; Mckenzie, Grahame; Abell, Chris; Skidmore, John; Venkitaraman, Ashok R.; Hyvonen, Marko
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Rapid discovery of monoclonal antibodies by microfluidics-enabled FACS of single pathogen-specific antibody-secreting cells
errNATURE BIOTECHNOLOGY
IF41.7
err2024-08-14
err0
errOAAI
errFischer, Katrin; Lulla, Aleksei; So, Tsz Y.; Pereyra-Gerber, Pehuen; Raybould, Matthew I. J.; Kohler, Timo N.; Yam-Puc, Juan Carlos; Kaminski, Tomasz S.; Hughes, Robert; Pyeatt, Gwendolyn L.; Leiss-Maier, Florian; Brear, Paul; Matheson, Nicholas J.; Deane, Charlotte M.; Hyvoenen, Marko; Thaventhiran, James E. D.; Hollfelder, Florian
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errSave
Unlocking Enhanced Immunity in Pancreatic Ductal Adenocarcinoma: Activins Interplay with CAF-Stroma Mechanisms
errBRITISH JOURNAL OF SURGERY
IF8.7
err2024-03-18
err0
PREAI
errMccluney, Simon; Park, Danielle; Miller, Daniel; Bloxham, Robert; Mehic, Merima; de Vries, Emma; Wang, Xuelu; Wilkinson, Robert; Hunt, James; Hyvonen, Marko; Boeing, Stefan; Sarker, Debashis; Hill, Caroline
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Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors
errNATURE CHEMICAL BIOLOGY
IF13.7
err2023-10-30
err17
errOAAI
errReinecke, Maria; Brear, Paul; Vornholz, Larsen; Berger, Benedict-Tilmann; Seefried, Florian; Wilhelm, Stephanie; Samaras, Patroklos; Gyenis, Laszlo; Litchfield, David William; Medard, Guillaume; Mueller, Susanne; Ruland, Jurgen; Hyvonen, Marko; Wilhelm, Mathias; Kuster, Bernhard
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SARS-CoV-2 Spike protein peptides displayed in the Pyrococcus furiosus RAD system preserve epitopes antigenicity, immunogenicity, and virus-neutralizing activity of antibodies
errSCIENTIFIC REPORTS
IF3.9
err2023-10-05
err2
errOAAI
errCioffi, Victor Bolsanelli; de Castro-Amarante, Maria Fernanda; Lulla, Aleksei; Andreata-Santos, Robert; Cruz, Mario Costa; Ramos Moreno, Ana Carolina; Silva, Mariangela de Oliveira; Peres, Bianca de Miranda; Gondim de Freitas Junior, Lucio Holanda; Moraes, Carolina Borsoi; Durigon, Edison Luiz; Gordon, Nicola Coker; Hyvoenen, Marko; de Souza Ferreira, Luis Carlos; Balan, Andrea
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Development of isoselenazolium chlorides as selective pyruvate kinase isoform M2 inhibitors
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-09-01
err2
PREAI
errDimitrijevs, Pavels; Makrecka-Kuka, Marina; Bogucka, Agnieszka; Hyvonen, Marko; Pantelejevs, Teodors; Arsenyan, Pavel
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Structure-Guided Chemical Optimization of Bicyclic Peptide (Bicycle) Inhibitors of Angiotensin-Converting Enzyme 2
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-07-11
err2
PREAI
errHarman, Maximilian A. J.; Stanway, Steven J. J.; Scott, Heather; Demydchuk, Yuliya; Bezerra, Gustavo Arruda; Pellegrino, Simone; Chen, Liuhong; Brear, Paul; Lulla, Aleksei; Hyvonen, Marko; Beswick, Paul J. J.; Skynner, Michael J. J.
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Age-associated B cells predict impaired humoral immunity after COVID-19 vaccination in patients receiving immune checkpoint blockade
errNATURE COMMUNICATIONS
IF15.7
err2023-06-27
err15
errOAAI
errYam-Puc, Juan Carlos; Hosseini, Zhaleh C.; Horner, Emily; Gerber, Pehuen Pereyra; Beristain-Covarrubias, Nonantzin; Hughes, Robert; Lulla, Aleksei; Rust, Maria; Boston, Rebecca; Ali, Magda; Fischer, Katrin; Simmons-Rosello, Edward; O'Reilly, Martin; Robson, Harry H.; Booth, Lucy; Kahanawita, Lakmini; Correa-Noguera, Andrea; Favara, David; Ceron-Gutierrez, Lourdes; Keller, Baerbel; Craxton, Andrew; Anderson, Georgina S. F.; Sun, Xiao-Ming; Elmer, Anne; Saunders, Caroline; Bermperi, Areti; Jose, Sherly; Kingston, Nathalie E.; Mulroney, Thomas; Pinon, Lucia P. G. A.; Chapman, Michael; Grigoriadou, Sofia E.; MacFarlane, Marion R.; Willis, Anne; Patil, Kiran; Spencer, Sarah; Staples, Emily S.; Warnatz, Klaus; Buckland, Matthew; Hollfelder, Florian; Hyvonen, Marko; Doffinger, Rainer; Parkinson, Christine J.; Lear, Sara; Matheson, Nicholas; Thaventhiran, James E. D.
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Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2
errNATURE COMMUNICATIONS
IF15.7
err2023-06-16
err9
errOAAI
errGaynor, Katherine U. U.; Vaysburd, Marina; Harman, Maximilian A. J.; Albecka, Anna; Jeffrey, Phillip; Beswick, Paul; Papa, Guido; Chen, Liuhong; Mallery, Donna; McGuinness, Brian; Van Rietschoten, Katerine; Stanway, Steven; Brear, Paul; Lulla, Aleksei; Ciazynska, Katarzyna; Chang, Veronica T. T.; Sharp, Jo; Neary, Megan; Box, Helen; Herriott, Jo; Kijak, Edyta; Tatham, Lee; Bentley, Eleanor G. G.; Sharma, Parul; Kirby, Adam; Han, Ximeng; Stewart, James P. P.; Owen, Andrew; Briggs, John A. G.; Hyvonen, Marko; Skynner, Michael J. J.; James, Leo C. C.
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Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-03-01
err6
errOAAI
errNain-Perez, Amalyn; Nilsson, Oscar; Lulla, Aleksei; Haversen, Liliana; Brear, Paul; Liljenberg, Sara; Hyvonen, Marko; Boren, Jan; Grotli, Morten
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A versatile Halo- and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-01-12
err5
errOAAI
errJatzlau, Jerome; Burdzinski, Wiktor; Trumpp, Michael; Obendorf, Leon; Rossmann, Kilian; Ravn, Katharina; Hyvonen, Marko; Bottanelli, Francesca; Broichhagen, Johannes; Knaus, Petra
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Research Directions

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Co-authors
Cooperation Journals
P
Peter ten Dijke
H-index: 147 · Papers: 794
E
Ewan Birney
H-index: 142 · Papers: 500
D
David P. Lane
H-index: 136 · Papers: 959
C
Carol V. Robinson
H-index: 132 · Papers: 818
M
Mathias Uhlén
H-index: 131 · Papers: 1.1K
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