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I

Irimpan I. Mathews

SLAC National Accelerator Laboratory

42H-index
195Paper Count
4.9KCitation Count
Published Papers 42
Publication Date
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Catabolism of lignin-related methoxylated compounds in white-rot fungi utilizes non-canonical oxidoreductases
errCell Reports
IF6.9
err2026-05-30
err0
errOAAI
errAlexa Schwartz; Eugene Kuatsjah; Irimpan I. Mathews; Hugh D. Mitchell; Samuel O. Purvine; Elizabeth K. Eder; David W. Hoyt; Lye Meng Markillie; Meagan C. Burnet; Sean P. Woodworth; Morgan A. Ingraham; Kelsey J. Ramirez; Lummy M.O. Monteiro; Ritimukta Sarangi; John E. McGeehan; Davinia Salvachúa
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Covalent Drug Binding in Live Cells Monitored by Mid-Infrared Quantum Cascade Laser Spectroscopy: Photoactive Yellow Protein as a Model System
errJournal of the American Chemical Society
IF15.6
err2025-12-14
err0
PREAI
errSrijit Mukherjee; Steven D. E. Fried; Nathalie Y. Hong; Nahal Bagheri; Jacek Kozuch; Irimpan I. Mathews; Jacob M. Kirsh; Steven G. Boxer
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errSave
Designing Cyclic Nitrogen-Bridged Sulfonamides with Anti-Cancer Activity
errCHEMMEDCHEM
IF3.4
err2025-05-14
err0
errOAAI
errBenedikt W. Grau; Arpit Dheeraj; Irimpan I. Mathews; Dhanir Tailor; Sanjay V. Malhotra
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errSave
A hidden cysteine in Fis1 targeted to prevent excessive mitochondrial fission and dysfunction under oxidative stress
errNATURE COMMUNICATIONS
IF15.7
err2025-05-06
err0
errOAAI
errPokhrel, Suman; Heo, Gwangbeom; Mathews, Irimpan; Yokoi, Shun; Matsui, Tsutomu; Mitsutake, Ayori; Wakatsuki, Soichi; Mochly-Rosen, Daria
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errSave
Application of Amber Suppression To Study the Role of Tyr M210 in Electron Transfer in Rhodobacter sphaeroides Photosynthetic Reaction Centers
errJOURNAL OF PHYSICAL CHEMISTRY B
IF2.9
err2025-03-26
err0
PREAI
errTran, Khoi N.; Faries, Kaitlyn M.; Magdaong, Nikki Cecil Macasinag; Mathews, Irimpan I.; Weaver, Jared B.; Kirsh, Jacob M.; Kirmaier, Christine; Boxer, Steven G.
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errSave
Structural and mechanistic analysis of Ca2+- dependent regulation of transglutaminase 2 activity using a Ca2+- bound intermediate state
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-07-03
err0
errOAAI
errSewa, Agnele S.; Besser, Harrison A.; Mathews, Irimpan I.; Khosla, Chaitan
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errSave
Structural insights reveal interplay between LAG-3 homodimerization, ligand binding, and function
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-03-14
err7
errOAAI
errSilberstein, John L.; Du, Jasper; Chan, Kun-Wei; Frank, Jessica A.; Mathews, Irimpan I.; Kim, Yong Bin; You, Jia; Lu, Qiao; Liu, Jia; Philips, Elliot A.; Liu, Phillip; Rao, Eric; Fernandez, Daniel; Rodriguez, Grayson E.; Kong, Xiang-Peng; Wang, Jun; Cochran, Jennifer R.
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errSave
Structural and Mechanistic Analysis of Ca2+Dependent Regulation of Transglutaminase 2 Activity
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err0
errOAAI
errSewa, Agnele; Besser, Harrison; Mathews, Irimpan; Khosla, Chaitan
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errSave
Triepoxide formation by a flavin-dependent monooxygenase in monensin biosynthesis
errNATURE COMMUNICATIONS
IF15.7
err2023-10-07
err7
errOAAI
errWang, Qian; Liu, Ning; Deng, Yaming; Guan, Yuze; Xiao, Hongli; Nitka, Tara A.; Yang, Hui; Yadav, Anju; Vukovic, Lela; Mathews, Irimpan I.; Chen, Xi; Kim, Chu-Young
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Structural and functional analyses of the echinomycin resistance conferring protein Ecm16 from Streptomyces lasalocidi
errSCIENTIFIC REPORTS
IF3.9
err2023-05-17
err4
errOAAI
errGade, Priyanka; Erlandson, Amanda; Ullah, Anwar; Chen, Xi; Mathews, Irimpan I.; Mera, Paola E.; Kim, Chu-Young
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errSave
Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2
errNATURE COMMUNICATIONS
IF15.7
err2023-03-28
err38
errOAAI
errSanders, Brian C.; Pokhrel, Suman; Labbe, Audrey D.; Mathews, Irimpan I.; Cooper, Connor J.; Davidson, Russell B.; Phillips, Gwyndalyn; Weiss, Kevin L.; Zhang, Qiu; O'Neill, Hugh; Kaur, Manat; Schmidt, Jurgen G.; Reichard, Walter; Surendranathan, Surekha; Parvathareddy, Jyothi; Phillips, Lexi; Rainville, Christopher; Sterner, David E.; Kumaran, Desigan; Andi, Babak; Babnigg, Gyorgy; Moriarty, Nigel W.; Adams, Paul D.; Joachimiak, Andrzej; Hurst, Brett L.; Kumar, Suresh; Butt, Tauseef R.; Jonsson, Colleen B.; Ferrins, Lori; Wakatsuki, Soichi; Galanie, Stephanie; Head, Martha S.; Parks, Jerry M.
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Protein Electric Fields Enable Faster and Longer-Lasting Covalent Inhibition of β-Lactamases
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2022-11-03
err16
errOAAI
errJi, Zhe; Kozuch, Jacek; Mathews, Irimpan I.; Diercks, Christian S.; Shamsudin, Yasmin; Schulz, Mirjam A.; Boxer, Steven G.
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errSave
Structural and functional characterization of NEMO cleavage by SARS-CoV-2 3CLpro
errNATURE COMMUNICATIONS
IF15.7
err2022-09-08
err17
errOAAI
errHameedi, Mikhail Ali; Prates, Erica T.; Garvin, Michael R.; Mathews, Irimpan; Amos, B. Kirtley; Demerdash, Omar; Bechthold, Mark; Iyer, Mamta; Rahighi, Simin; Kneller, Daniel W.; Kovalevsky, Andrey; Irle, Stephan; Van-Quan Vuong; Mitchell, Julie C.; Labbe, Audrey; Galanie, Stephanie; Wakatsuki, Soichi; Jacobson, Daniel
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errSave
Energetic Basis and Design of Enzyme Function Demonstrated Using GFP, an Excited-State Enzyme
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2022-02-24
err11
errOAAI
errLin, Chi-Yun; Romei, Matthew G.; Mathews, Irimpan I.; Boxer, Steven G.
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errSave
Protein sequence design with a learned potential
errNATURE COMMUNICATIONS
IF15.7
err2022-02-08
err86
errOAAI
errAnand, Namrata; Eguchi, Raphael; Mathews, Irimpan I.; Perez, Carla P.; Derry, Alexander; Altman, Russ B.; Huang, Po-Ssu
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errSave
Photosynthetic reaction center variants made via genetic code expansion show Tyr at M210 tunes the initial electron transfer mechanism
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2021-12-14
err15
errOAAI
errWeaver, Jared Bryce; Lin, Chi-Yun; Faries, Kaitlyn M.; Mathews, Irimpan I.; Russi, Silvia; Holten, Dewey; Kirmaier, Christine; Boxer, Steven G.
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errSave
Ecm16 protein confers resistance against the DNA intercalator antibiotic echinomycin
errFASEB JOURNAL
IF4.2
err2021-05-14
err0
PREAI
errGade, Priyanka; Erlandson, Amanda; Mathews, Irimpan I.; Chen, Xi; Mera, Paola; Kim, Chu-Young
errShare
errSave
Antibody Probes of Module 1 of the 6-Deoxyerythronolide B Synthase Reveal an Extended Conformation During Ketoreduction
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2020-08-10
err12
errOAAI
errCogan, Dillon P.; Li, Xiuyuan; Sevillano, Natalia; Mathews, Irimpan I.; Matsui, Tsutomu; Craik, Charles S.; Khosla, Chaitan
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errSave
A CLC-ec1 mutant reveals global conformational change and suggests a unifying mechanism for the CLC Cl-/H+ transport cycle
errELIFE
IF0
err2020-04-20
err30
errOAAI
errChavan, Tanmay S.; Cheng, Ricky C.; Jiang, Tao; Mathews, Irimpan I.; Stein, Richard A.; Koehl, Antoine; Mchaourab, Hassane S.; Tajkhorshid, Emad; Maduke, Merritt
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errSave
Ecm16 protein confers resistance against the DNA intercalator antibiotic echinomycin
errFASEB JOURNAL
IF4.2
err2020-04-18
err0
errOAAI
errGade, Priyanka; Erlandson, Amanda; Mathews, Irimpan; Chen, Xi; Mera, Paola; Kim, Chu-Young
errShare
errSave

Research Directions

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