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The Role of Intrinsically Disordered Domains in Regulating G Protein-Coupled Receptor Signaling Xu, Jun; Qiu, Ruoyi; Garces, Alexander M.; Hubner, Harald; Xu, Xinyu; Hao, Chengyu; Weikert, Dorothee; Gmeiner, Peter; Lerch, Michael T.; Kobilka, Brian K. Share Save
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Mechanistic insights into G-protein coupling with an agonist-bound G-protein-coupled receptor Batebi, Hossein; Perez-Hernandez, Guillermo; Rahman, Sabrina N.; Lan, Baoliang; Kamprad, Antje; Shi, Mingyu; Speck, David; Tiemann, Johanna K. S.; Guixa-Gonzalez, Ramon; Reinhardt, Franziska; Stadler, Peter F.; Papasergi-Scott, Makaia M.; Skiniotis, Georgios; Scheerer, Patrick; Kobilka, Brian K.; Mathiesen, Jesper M.; Liu, Xiangyu; Hildebrand, Peter W. Share Save
Structural basis of α1A-adrenergic receptor activation and recognition by an extracellular nanobody Toyoda, Yosuke; Zhu, Angqi; Kong, Fang; Shan, Sisi; Zhao, Jiawei; Wang, Nan; Sun, Xiaoou; Zhang, Linqi; Yan, Chuangye; Kobilka, Brian K.; Liu, Xiangyu Share Save
Structure based approaches on fentanyl template to design novel mu opioid modulators Ople, Rohini; Wang, Haoqing; Li, Qiongyu; Polacco, Ben; Bernhard, Sarah; Appourchaux, Kevin; Sribhashyam, Sashrik; Eans, Shainnel; Huttenhain, Ruth; McLaughlin, Jay; Kobilka, Brian; Majumdar, Susruta Share Save
Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics (vol 14, 2138, 2023) Xu, Xinyu; Shonberg, Jeremy; Kaindl, Jonas; Clark, Mary J.; Stoessel, Anne; Maul, Luis; Mayer, Daniel; Huebner, Harald; Hirata, Kunio; Venkatakrishnan, A. J.; Dror, Ron O.; Kobilka, Brian K.; Sunahara, Roger K.; Liu, Xiangyu; Gmeiner, Peter Share Save
Structural basis for activation of CB1 by an endocannabinoid analog Kumar, Kaavya Krishna; Robertson, Michael J.; Thadhani, Elina; Wang, Haoqing; Suomivuori, Carl-Mikael; Powers, Alexander S.; Ji, Lipin; Nikas, Spyros P.; Dror, Ron O.; Inoue, Asuka; Makriyannis, Alexandros; Skiniotis, Georgios; Kobilka, Brian Share Save
Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics Xu, Xinyu; Shonberg, Jeremy; Kaindl, Jonas; Clark, Mary J. J.; Stoessel, Anne; Maul, Luis; Mayer, Daniel; Huebner, Harald; Hirata, Kunio; Venkatakrishnan, A. J.; Dror, Ron O. O.; Kobilka, Brian K. K.; Sunahara, Roger K. K.; Liu, Xiangyu; Gmeiner, Peter Share Save
Function and dynamics of the intrinsically disordered carboxyl terminus of β2 adrenergic receptor Heng, Jie; Hu, Yunfei; Perez-Hernandez, Guillermo; Inoue, Asuka; Zhao, Jiawei; Ma, Xiuyan; Sun, Xiaoou; Kawakami, Kouki; Ikuta, Tatsuya; Ding, Jienv; Yang, Yujie; Zhang, Lujia; Peng, Sijia; Niu, Xiaogang; Li, Hongwei; Guixa-Gonzalez, Ramon; Jin, Changwen; Hildebrand, Peter W.; Chen, Chunlai; Kobilka, Brian K. Share Save
Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor Xu, Jun; Wang, Qinggong; Huebner, Harald; Hu, Yunfei; Niu, Xiaogang; Wang, Haoqing; Maeda, Shoji; Inoue, Asuka; Tao, Yuyong; Gmeiner, Peter; Du, Yang; Jin, Changwen; Kobilka, Brian K. Share Save
Insights into distinct signaling profiles of the μOR activated by diverse agonists Qu, Qianhui; Huang, Weijiao; Aydin, Deniz; Paggi, Joseph M.; Seven, Alpay B.; Wang, Haoqing; Chakraborty, Soumen; Che, Tao; DiBerto, Jeffrey F.; Robertson, Michael J.; Inoue, Asuka; Suomivuori, Carl-Mikael; Roth, Bryan L.; Majumdar, Susruta; Dror, Ron O.; Kobilka, Brian K.; Skiniotis, Georgios Share Save
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Membrane Phosphoinositides Stabilize GPCR-arrestin Complexes and Provide Temporal Control of Complex Assembly and Dynamics Janetzko, John; Kise, Ryoji; Barsi-Rhyne, Benjamin; Siepe, Dirk H.; Heydenreich, Franziska M.; Masureel, Matthieu; Kawakami, Kouki; Garcia, K. C.; von Zastrow, Mark; Inoue, Asuka; Kobilka, Brian K. Share Save
Structure-Based Evolution of G Protein-Biased μ-Opioid Receptor Agonists Wang, Haoqing; Hetzer, Florian; Huang, Weijiao; Qu, Qianhui; Meyerowitz, Justin; Kaindl, Jonas; Huebner, Harald; Skiniotis, Georgios; Kobilka, Brian K.; Gmeiner, Peter Share Save
Structural determinants of dual incretin receptor agonism by tirzepatide Sun, Bingfa; Willard, Francis S.; Feng, Dan; Alsina-Fernandez, Jorge; Chen, Qi; Vieth, Michal; Ho, Joseph D.; Showalter, Aaron D.; Stutsman, Cynthia; Ding, Liyun; Suter, Todd M.; Dunbar, James D.; Carpenter, John W.; Mohammed, Faiz Ahmad; Aihara, Eitaro; Brown, Robert A.; Bueno, Ana B.; Emmerson, Paul J.; Moyers, Julie S.; Kobilka, Tong Sun; Coghlan, Matthew P.; Kobilka, Brian K.; Sloop, Kyle W. Share Save
Foldable Detergents for Membrane Protein Study: Importance of Detergent Core Flexibility in Protein Stabilization Ghani, Lubna; Kim, Seonghoon; Wang, Haoqing; Lee, Hyun Sung; Mortensen, Jonas S.; Katsube, Satoshi; Du, Yang; Sadaf, Aiman; Ahmed, Waqar; Byrne, Bernadette; Guan, Lan; Loland, Claus J.; Kobilka, Brian K.; Im, Wonpil; Chae, Pil Seok Share Save
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