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Dustin Dovala

novartis

19H-index
63Paper Count
1.7KCitation Count
Published Papers 28
Publication Date
Targeted Transcriptional Repression by Induced Proximity
err2026-06-11
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errOAAI
errChristian E. Stieger; Xinru Chen; Christina C. Kuismi; Dustin Dovala; Daniel Fuller; Andreas O. Frank; Mikias Woldegiorgis; Megan Bruce-Smythe; Fabian Wu; Nicolas Pizzato; Jeffrey McKenna; Cory Johannessen; Barna D. Fodor; Markus Schirle; Daniel K. Nomura
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Discovery of EGT710; an Oral Nonpeptidomimetic Reversible Covalent SARS-CoV-2 Main Protease Inhibitor
err2026-02-09
err0
PREAI
errJulien P. N. Papillon; Jun Yuan; Matthew J. Hesse; Lei Zhang; Richard I. Robinson; Nathaniel F. Ware; Viktor Hornak; Rajeshri G. Karki; Tom Kirrane; Keira Garland; Sajan Joseph; Stephanie A. Moquin; Suresh B. Lakshminarayana; Laura Tandeske; Dustin Dovala; Mark Knapp; Elizabeth Ornelas; Daniel Fuller; Pei-i Ho; Xuping Xie; Katarina Vulic; Suzanne M. Skolnik; Jinhai Gao; Mark Zambrowski; Meike Spiess; José S. Duca; Scott A. Busby; Markus Schirle; Michael Robinson; Pei-Yong Shi; Heinz E. Moser; Christopher Sarko; James E. Bradner; Thierry T. Diagana; John A. Tallarico
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Cooperativity and communication between the active sites of the dimeric SARS-CoV-2 main protease
err2026-01-16
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PREAI
errZvornicanin, Sarah N.; Shaqra, Ala M.; Flynn, Julia; Intravaia, Lauren E.; Martinez, Heidi Carias; Jia, Weiping; Gupta, Devendra Kumar; Moquin, Stephanie; Dovala, Dustin; Bolon, Daniel N.; Kelch, Brian A.; Schiffer, Celia A.; Yilmaz, Nese Kurt
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Structural Analysis of Inhibitor Binding to the Feline Enteric Coronavirus (FECV) Main Protease
err2025-11-18
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errOAAI
errArooma Maryam; Stephanie A. Moquin; Dustin Dovala; Jagroop Kaur; Nese Kurt Yilmaz; Ala M. Shaqra; Celia A. Schiffer
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Sulfinyl Aziridines as Stereoselective Covalent Destabilizing Degraders of the Oncogenic Transcription Factor MYC
err2025-09-25
err0
PREAI
errHannah T. Rosen; Kelvin Li; Christian E. Stieger; Erin L. Li; Brynne Currier; Scott M. Brittain; Francisco J. Garcia; Diana C. Beard; Michael D. Jones; Sandra Haenni-Holzinger; Dustin Dovala; Jeffrey M. McKenna; Markus Schirle; Thomas J. Maimone; Daniel K. Nomura
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A small-molecule VHL molecular glue degrader for cysteine dioxygenase 1
err2025-06-24
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errOAAI
errAntonin Tutter; Dennis Buckley; Andrei A. Golosov; Xiaolei Ma; Wei Shu; Daniel J. J. McKay; Veronique Darsigny; Dustin Dovala; Rohan Beckwith; Jonathan Solomon; Pasupuleti Rao; Lei Xu; Aleem Fazal; Andreas Lingel; Charles Wartchow; Jennifer S. Cobb; Amanda Hachey; Jennifer Tullai; Gregory A. Michaud
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Molecular mechanisms of drug resistance and compensation in SARS-CoV-2 main protease: the interplay between E166 and L50
errMBIO
IF4.7
err2025-05-14
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errOAAI
errZvornicanin, Sarah N.; Shaqra, Ala M.; Flynn, Julia; Martinez, Heidi Carias; Jia, Weiping; Moquin, Stephanie; Dovala, Dustin; Bolon, Daniel N.; Yilmaz, Nese Kurt; Schiffer, Celia A.
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Identification of Potent, Broad-Spectrum Coronavirus Main Protease Inhibitors for Pandemic Preparedness
err2024-09-27
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errOAAI
errBarkan, David T.; Garland, Keira; Zhang, Lei; Eastman, Richard T.; Hesse, Matthew; Knapp, Mark; Ornelas, Elizabeth; Tang, Jenny; Cortopassi, Wilian Augusto; Wang, Yu; King, Frederick; Jia, Weiping; Nguyen, Zachary; Frank, Andreas O.; Chan, Ryan; Fang, Eric; Fuller, Daniel; Busby, Scott; Carias, Heidi; Donahue, Kristine; Tandeske, Laura; Diagana, Thierry T.; Jarrousse, Nadine; Moser, Heinz; Sarko, Christopher; Dovala, Dustin; Moquin, Stephanie; Marx, Vanessa M.
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Ophiobolin A Covalently Targets Mitochondrial Complex IV Leading to Metabolic Collapse in Cancer Cells
err2024-05-13
err1
PREAI
errGowans, Flor A.; Thach, Danny Q.; Zhu, Zhouyang; Wang, Yangzhi; Poblano, Belen E. Altamirano; Dovala, Dustin; Tallarico, John A.; Mckenna, Jeffrey M.; Schirle, Markus; Maimone, Thomas J.; Nomura, Daniel K.
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Contributions of Hyperactive Mutations in Mpro from SARS-CoV-2 to Drug Resistance
err2024-03-12
err7
PREAI
errFlynn, Julia M.; Zvornicanin, Sarah N.; Tsepal, Tenzin; Shaqra, Ala M.; Yilmaz, Nese Kurt; Jia, Weiping; Moquin, Stephanie; Dovala, Dustin; Schiffer, Celia A.; Bolon, Daniel N. A.
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Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon
err2023-12-12
err6
errOAAI
errMa, Xiaolei; Leon, Barbara; Ornelas, Elizabeth; Dovala, Dustin; Tandeske, Laura; Luu, Catherine; Pardee, Gwynn; Widger, Stephania; Solomon, Jonathan M.; Beckwith, Rohan E. J.; Moser, Heinz; Clifton, Matthew C.; Wartchow, Charles A.
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Rational Chemical Design of Molecular Glue Degraders (vol 9, pg 915, 2023)
err2023-07-21
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errOAAI
errToriki, Ethan S.; Papatzimas, James W.; Nishikawa, Kaila; Dovala, Dustin; Frank, Andreas O.; Hesse, Matthew J.; Dankova, Daniela; Song, Jae-Geun; Bruce-Smythe, Megan; Struble, Heidi; Garcia, Francisco J.; Brittain, Scott M.; Kile, Andrew C.; McGregor, Lynn M.; McKenna, Jeffrey M.; Tallarico, John A.; Schirle, Markus; Nomura, Daniel K.
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Systematic Analyses of the Resistance Potential of Drugs Targeting SARS-CoV-2 Main Protease
err2023-06-30
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errOAAI
errFlynn, Julia M.; Huang, Qiu Yu J.; Zvornicanin, Sarah N.; Schneider-Nachum, Gila; Shaqra, Ala M.; Yilmaz, Nese Kurt; Moquin, Stephanie A.; Dovala, Dustin; Schiffer, Celia A.; Bolon, Daniel N. A.
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Rational Chemical Design of Molecular Glue Degraders
err2023-04-11
err58
errOAAI
errToriki, Ethan S.; Papatzimas, James W.; Nishikawa, Kaila; Dovala, Dustin; Frank, Andreas O.; Hesse, Matthew J.; Dankova, Daniela; Song, Jae-Geun; Bruce-Smythe, Megan; Struble, Heidi; Garcia, Francisco J.; Brittain, Scott M.; Kile, Andrew C.; McGregor, Lynn M.; McKenna, Jeffrey M.; Tallarico, John A.; Schirle, Markus; Nomura, Daniel K.
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Chemoproteomics-enabled discovery of a covalent molecular glue degrader targeting NF-KB
err2023-04-01
err48
errOAAI
errKing, Elizabeth A.; Cho, Yoojin; Hsu, Nathan S.; Dovala, Dustin; Mckenna, Jeffrey M.; Tallarico, John A.; Schirle, Markus; Nomura, Daniel K.
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Targeted Protein Degradation through E2 Recruitment
err2023-03-20
err27
errOAAI
errForte, Nafsika; Dovala, Dustin; Hesse, Matthew J.; McKenna, Jeffrey M.; Tallarico, John A.; Schirle, Markus; Nomura, Daniel K.
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Crystal Structures of Inhibitor-Bound Main Protease from Delta- and Gamma-Coronaviruses
err2023-03-18
err6
errOAAI
errZvornicanin, Sarah N.; Shaqra, Ala M.; Huang, Qiuyu J.; Ornelas, Elizabeth; Moghe, Mallika; Knapp, Mark; Moquin, Stephanie; Dovala, Dustin; Schiffer, Celia A.; Kurt Yilmaz, Nese
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An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4
err2022-12-09
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errOAAI
errGonzalez-Valero, Angel; Reeves, Audrey G.; Page, Annika C. S.; Moon, Patrick J.; Miller, Edward; Coulonval, Katia; Crossley, Steven W. M.; Xie, Xiao; He, Dan; Musacchio, Patricia Z.; Christian, Alec H.; McKenna, Jeffrey M.; Lewis, Richard A.; Fang, Eric; Dovala, Dustin; Lu, Yipin; McGregor, Lynn M.; Schirle, Markus; Tallarico, John A.; Roger, Pierre P.; Toste, F. Dean; Chang, Christopher J.
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Defining the substrate envelope of SARS-CoV-2 main protease to predict and avoid drug resistance
err2022-06-21
err64
errOAAI
errShaqra, Ala M.; Zvornicanin, Sarah N.; Huang, Qiu Yu J.; Lockbaum, Gordon J.; Knapp, Mark; Tandeske, Laura; Bakan, David T.; Flynn, Julia; Bolon, Daniel N. A.; Moquin, Stephanie; Dovala, Dustin; Kurt Yilmaz, Nese; Schiffer, Celia A.
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Comprehensive fitness landscape of SARS-CoV-2 Mpro reveals insights into viral resistance mechanisms
err2022-06-20
err64
errOAAI
errFlynn, Julia M.; Samant, Neha; Schneider-Nachum, Gily; Barkan, David T.; Yilmaz, Nese Kurt; Schiffer, Celia A.; Moquin, Stephanie A.; Dovala, Dustin; Bolon, Daniel N. A.
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