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Identifying distinct prognostic and predictive contributions of tumor epithelium versus tumor microenvironment in colorectal cancer Yang, Mingli; Nebozhyn, Michael V.; Schell, Michael J.; Gandhi, Nishant; Pflieger, Lance; Loboda, Andrey; Pledger, W. Jack; Soundararajan, Ramani; Maurin, Michelle; Wang, Heiman; Silva, Jetsen Rodriguez; Alden, Ashley; Coppola, Domenico; Elliott, Andrew; Sledge, George; Khushman, Moh'd; Lou, Emil; Goel, Sanjay; Yeatman, Timothy J. Share Save
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Exploring intrapatient heterogeneity in metastatic breast cancer: Insights into tumor evolution from a warm procurement trial Bishara, Isaac; Liu, Xuan; Griffiths, Jason; Liu, Jiayi; Cosgrove, Patrick; McQuerry, Jasmine R.; Chi, Feng; Wallet, Pierre; Grolmusz, Vince K.; Copeland, Benjamin; Pflieger, Lance; Chen, Jinfeng; Majumdar, Sumana; Ronquillo, Grace; Crowder, Terron; Emond, Rena; Factor, Rachel; Barragan, Eliza; Bowtell, David; Cohen, Adam; Schmolze, Daniel D.; Lee, Peter; Ihle, Kena; Tumyan, Lusine; Nath, Aritro; Waisman, James; Bild, Andrea; Chang, Jeff Share Save
Gene expression signature quantifies the cellular contribution of the tumor vs. the microenvironment in determining colorectal cancer prognosis and therapeutic outcome Yang, Mingli; Yeatman, Timothy J.; Nebozhyn, Michael V.; Schell, Michael J.; Pflieger, Lance; Loboda, Andrey; Pledger, Warren J.; Soundararajan, Ramani; Maurin, Michelle; Wang, Heiman; Silva, Jetsen Rodriguez; Alden, Ashley Share Save
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TP-317, a first-in-class resolvin E1 small molecule, drives adjuvant efficacy in solid tumors by engaging innate and adaptive anti-tumor immunity in the tumor microenvironment (TME) and has neoadjuvant potential Parkinson, John F.; Rothenberger, Eva; Kelly, Abigail; Bielenberg, Diane; Attaya, Ahmed; Huang, Sui; Pflieger, Lance; Klohs, Wayne; Mathias, Gary; Panigrahy, Dipak Share Save
Lifespan-extending interventions induce consistent patterns of fatty acid oxidation in mouse livers (vol 6, 768, 2023) Watanabe, Kengo; Wilmanski, Tomasz; Baloni, Priyanka; Robinson, Max; Garcia, Gonzalo G.; Hoopmann, Michael R.; Midha, Mukul K.; Baxter, David H.; Maes, Michal; Morrone, Seamus R.; Crebs, Kelly M.; Kapil, Charu; Kusebauch, Ulrike; Wiedrick, Jack; Lapidus, Jodi; Pflieger, Lance; Lausted, Christopher; Roach, Jared C.; Glusman, Gwenlyn; Cummings, Steven R.; Schork, Nicholas J.; Price, Nathan D.; Hood, Leroy; Miller, Richard A.; Moritz, Robert L.; Rappaport, Noa Share Save
Lifespan-extending interventions induce consistent patterns of fatty acid oxidation in mouse livers Watanabe, Kengo; Wilmanski, Tomasz; Baloni, Priyanka; Robinson, Max; Garcia, Gonzalo G.; Hoopmann, Michael R.; Midha, Mukul K.; Baxter, David H.; Maes, Michal; Morrone, Seamus R.; Crebs, Kelly M.; Kapil, Charu; Kusebauch, Ulrike; Wiedrick, Jack; Lapidus, Jodi; Pflieger, Lance; Lausted, Christopher; Roach, Jared C.; Glusman, Gwenlyn; Cummings, Steven R.; Schork, Nicholas J.; Price, Nathan D.; Hood, Leroy; Miller, Richard A.; Moritz, Robert L.; Rappaport, Noa Share Save
TP317, a first-in-class resolvin E1 small molecule, potentiates the efficacy of immune checkpoint (ICI) inhibitors in ICI-resistant and ICI-sensitive tumors Kipper, Franciele C.; Rothenberger, Eva; Kelly, Abigail; Gillespie, Michael; Attaya, Ahmed; Bielenberg, Diane R.; Huang, Sui; Pflieger, Lance; Sciavolino, Frank; Mathias, Aaron; Klohs, Wayne; Parkinson, John; Mathias, Gary; Panigrahy, Dipak Share Save
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Spatial single-cell atlas of stage III colorectal cancer Su, Andrew; Tran, Minh; Lee, HoJoon; Sathe, Anuja; Bai, Xiangqi; Cruz, Richard; Pflieger, Lance; Nguyen, Quan; Ji, Hanlee P.; Rhodes, Terence Share Save
A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2 Scoles, Daniel R.; Gandelman, Mandi; Paul, Sharan; Dexheimer, Thomas; Dansithong, Warunee; Figueroa, Karla P.; Pflieger, Lance T.; Redlin, Scott; Kales, Stephen C.; Sun, Hongmao; Maloney, David; Damoiseaux, Robert; Henderson, Mark J.; Simeonov, Anton; Jadhav, Ajit; Pulst, Stefan M. Share Save
An integrative gene expression signature analysis identifies CMS4 KRAS-mutated colorectal cancers sensitive to combined MEK and SRC targeted therapy Yang, Mingli; Davis, Thomas B.; Pflieger, Lance; Nebozhyn, Michael, V; Loboda, Andrey; Wang, Heiman; Schell, Michael J.; Thota, Ramya; Pledger, W. Jack; Yeatman, Timothy J. Share Save
Evolution of core archetypal phenotypes in progressive high grade serous ovarian cancer Nath, Aritro; Cosgrove, Patrick A.; Mirsafian, Hoda; Christie, Elizabeth L.; Pflieger, Lance; Copeland, Benjamin; Majumdar, Sumana; Cristea, Mihaela C.; Han, Ernest S.; Lee, Stephen J.; Wang, Edward W.; Fereday, Sian; Traficante, Nadia; Salgia, Ravi; Werner, Theresa; Cohen, Adam L.; Moos, Philip; Chang, Jeffrey T.; Bowtell, David D. L.; Bild, Andrea H. Share Save
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Circulating immune cell phenotype dynamics reflect the strength of tumor-immune cell interactions in patients during immunotherapy Griffiths, Jason, I; Wallet, Pierre; Pflieger, Lance T.; Stenehjem, David; Liu, Xuan; Cosgrove, Patrick A.; Leggett, Neena A.; McQuerry, Jasmine A.; Shrestha, Gajendra; Rossetti, Maura; Sunga, Gemalene; Moos, Philip J.; Adler, Frederick R.; Chang, Jeffrey T.; Sharma, Sunil; Bild, Andrea H. Share Save