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K

Kaifu Chen

university of minnesota system

39H-index
184Paper Count
7.3KCitation Count
Published Papers 90
Publication Date
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Targeting FGFR signaling overcomes therapeutic resistance and immune evasion in oncogenic PIK3CA-driven serous-like endometrial cancer
errNature Communications
IF15.7
err2026-05-04
err0
errOAAI
errXin Cheng; Yadong Zhang; Changli Qian; Erica Holdridge; Guruprasad Ananda; Tao Jiang; Jing Ni; Shaozhen Xie; Hao Gu; Renlei Ji; Elena V. Ivanova; Marisa R. Nucci; Zhe Wang; Kaifu Chen; Bose Kochupurakkal; Gordon J. Freeman; Geoffrey I. Shapiro; Joyce Liu; Panagiotis A. Konstantinopoulos; Ursula Matulonis; Jean J. Zhao
errShare
errSave
A conserved hormonal signalling–H2A.Z axis rapidly reorganizes 3D chromatin interactions in adipocyte thermogenesis
errNature Metabolism
IF20.8
err2026-04-21
err0
errOAAI
errYang Zhang; Rongbin Zheng; Tadataka Tsuji; Chih-Hao Wang; Xiang-Yu Liu; Yu-Hang Xing; Justin Darcy; Matthew D. Lynes; Morten Lundh; Rini Arianti; Ferenc Győry; Rui Dong; Brice Emanuelli; Sarah E. Johnstone; Miguel N. Rivera; Endre Kristóf; C. Ronald Kahn; Kaifu Chen; Yu-Hua Tseng
errShare
errSave
A dual role of EZH2 in regulating A-to-I RNA editing and mRNA stability through ADAR
errNature Communications
IF15.7
err2026-03-26
err0
errOAAI
errYang Yi; Yanqiang Li; Rui Wang; Xufen Yu; Qi Liu; Chaehyun Yum; Yang Zhang; Yuanyuan Qiao; Aileen Szczepanski; Siqi Wu; Qiaqia Li; Ladan Fazli; Jiangchuan Shen; Xin Wang; Xiaoling Li; Ping Mu; Edward M. Schaeffer; Heather A. Hundley; Hengyao Niu; Arul M. Chinnaiyan; Lu Wang; Jinjun Shi; Jian Jin; Xuesen Dong; Wei Zhao; Kaifu Chen; Qi Cao
errShare
errSave
EZH2 crosstalk with RNA methylation promotes prostate cancer progression through modulation of m6A autoregulation pathway
errJournal of Clinical Investigation
IF13.6
err2026-01-16
err2
errOAAI
errYi, Yang; Fry, Joshua; Yum, Chaehyun; Wang, Rui; Wu, Siqi; Narayan, Sharath; Liu, Qi; Zhang, Xingxing; Oo, Htoo Zarni; Xie, Ning; Li, Yanqiang; Gao, Xinlei; Yu, Xufen; Hu, Xiaoping; Li, Qiaqia; Keseroglu, Kemal; Ozbudak, Ertugrul M.; Abdulkadir, Sarki A.; Chen, Kaifu; Jin, Jian; Zhao, Jonathan C.; Dong, Xuesen; Arango, Daniel; Yang, Rendong; Cao, Qi
errShare
errSave
3D spatial organization of heterogeneous nkx2.5+ progenitors in the zebrafish heart field pre-patterns cardiovascular development
errNature Communications
IF15.7
err2025-11-25
err0
errOAAI
errHakan Coskun; Yunxia Wang; Xinlei Gao; Kaifu Chen; C. Geoffrey Burns; Caroline E. Burns
errShare
errSave
KMT2D temporally activates neuronal transcriptional factor genes to mediate cerebellar granule cell differentiation
errScience Advances
IF12.5
err2025-09-26
err0
errOAAI
errShilpa S. Dhar; Kyung-Pil Ko; Jinho Jang; Calena Brown-Abel; Tao Lin; Sharad Awasthi; Kaifu Chen; Roy V. Sillitoe; Jae-Il Park; Min Gyu Lee
errShare
errSave
The chemokine receptor CXCR4 and its ligand CXCL12 (SDF-1) localize to ependymal cilia in brain ventricles
errVascular Pharmacology
IF3.5
err2025-09-09
err0
PREAI
errShahram Eisa-Beygi; Kulandaisamy Arulsamy; Kui Cui; Hao Wu; Beibei Wang; Kaifu Chen; Hong Chen
errShare
errSave
O-GlcNAcylation promotes angiogenic transdifferentiation to reverse vascular ischemia
errcardiovascular research
IF10.8
err2025-07-04
err0
PREAI
errShuang Li; Alexander J. Lu; Eric S. Nagueh; Yanqiang Li; Michael Graber; Kaylee N. Carter; Elisa Morales; Crystina L. Kriss; Kaifu Chen; Junchen Liu; Guangyu Wang; John P. Cooke; Li Lai
errShare
errSave
Rapid generation of functional vascular organoids via simultaneous transcription factor activation of endothelial and mural lineages
errCell Stem Cell
IF20.4
err2025-06-13
err0
PREAI
errLiyan Gong; Yadong Zhang; Yonglin Zhu; Umji Lee; Allen Chilun Luo; Xiang Li; Xi Wang; Danyang Chen; William T. Pu; Ruei-Zeng Lin; Minglin Ma; Miao Cui; Kaifu Chen; Kai Wang; Juan M. Melero-Martin
errShare
errSave
SCIG: Machine learning uncovers cell identity genes in single cells by genetic sequence codes
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-05-28
err0
errOAAI
errArulsamy, Kulandaisamy; Xia, Bo; Yu, Yang; Chen, Hong; Pu, William T.; Zhang, Lili; Chen, Kaifu
errShare
errSave
Heterozygous Kmt2d loss diminishes enhancers to render medulloblastoma cells vulnerable to combinatory inhibition of LSD1 and OXPHOS
errCELL REPORTS
IF6.9
err2025-05-01
err0
PREAI
errDhar, Shilpa S.; Brown, Calena; Rizvi, Ali; Reed, Lauren; Kotla, Sivareddy; Zod, Constantin; Abraham, Janak; Abe, Jun-Ichi; Rajaram, Veena; Chen, Kaifu; Lee, Min Gyu
errShare
errSave
RPA and Rad27 limit templated and inverted insertions at DNA breaks
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-12-03
err0
errOAAI
errYu, Yang; Wang, Xin; Fox, Jordan; Li, Qian; Yu, Yang; Hastings, P. J.; Chen, Kaifu; Ira, Grzegorz
errShare
errSave
Single-cell Analysis Reveals Endothelial Cell CD45 Deficiency Prevents Endothelial-to-Mesenchymal Transition (EndMT) in Atherosclerosis
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errPeng, Qianman; Arulsamy, Kulandai Samy; Lu, Wei; Zhu, Bo; Li, Kathryn; Singh, Bandana; Wu, Hao; Cui, Kui; Eisa-Beygi, Shahram; Nasim, Sana; Wylie-Sears, Jill; Malovichko, Marina; Sun, Liang; Wong, Scot; Cowan, Douglas; Srivastava, Sanjay; Wang, Da-Zhi; Chen, Kaifu; Bischoff, Joyce; Chen, Hong
errShare
errSave
Single-Cell Analysis Reveals Critical Role of Macrophage Epsin in Regulating Origin of Foam Cell in Atherosclerosis
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errArulsamy, Kulandai Samy; Cui, Kui; Chen, Kaifu; Chen, Hong
errShare
errSave
Targeting Liver Epsins Ameliorates Dyslipidemia in Atherosclerosis
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errZhu, Bo; Gupta, Krishan; Cui, Kui; Malovichko, Marrina; Srivastava, Sanjay; Chen, Kaifu; Shi, Jinjun; Chen, Hong
errShare
errSave
Epsin-Mediated PCSK9-LDLR Interaction: A New Therapeutic Target for Atherosclerosis
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errGupta, Krishan; Zhu, Bo; Chen, Kaifu; Chen, Hong
errShare
errSave
Transcriptional inhibition after irradiation occurs preferentially at highly expressed genes in a manner dependent on cell cycle progression
errELIFE
IF0
err2024-10-11
err0
errOAAI
errChen, Zulong; Wang, Xin; Gao, Xinlei; Arslanovic, Nina; Chen, Kaifu; Tyler, Jessica K.
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errSave
Robust differentiation of human pluripotent stem cells into mural progenitor cells via transient activation of NKX3.1
errNATURE COMMUNICATIONS
IF15.7
err2024-09-30
err0
errOAAI
errLee, Umji; Zhang, Yadong; Zhu, Yonglin; Luo, Allen Chilun; Gong, Liyan; Tremmel, Daniel M.; Kim, Yunhye; Villarreal, Victoria Sofia; Wang, Xi; Lin, Ruei-Zeng; Cui, Miao; Ma, Minglin; Yuan, Ke; Wang, Kai; Chen, Kaifu; Melero-Martin, Juan M.
errShare
errSave
RBFOX2 haploinsufficiency impairs cardiomyocyte adhesion and contractility through faulty RNA metabolism
errCIRCULATION RESEARCH
IF16.2
err2024-08-02
err0
PREAI
errHuang, Mengmeng; Gao, Xinlei; Trembley, Michael; Prondzynski, Maksymilian; Tharani, Yashasvi; Nawar, Farina; Zheng, Rongbin; Aigner, Stefan; Yeo, Gene; Pu, William; Chen, Kaifu; Burns, C. Geoffrey; Burns, Caroline
errShare
errSave
2'-O-methylation '-O-methylation at internal sites on mRNA promotes mRNA stability
errMOLECULAR CELL
IF16.6
err2024-06-01
err6
PREAI
errLi, Yanqiang; Yi, Yang; Gao, Xinlei; Wang, Xin; Zhao, Dongyu; Wang, Rui; Zhang, Li-Sheng; Gao, Boyang; Zhang, Yadong; Zhang, Lili; Cao, Qi; Chen, Kaifu
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
G
Gordon J. Freeman
H-index: 174 · Papers: 1.1K
C
Christine E. Seidman
H-index: 151 · Papers: 708
A
Arul M. Chinnaiyan
H-index: 144 · Papers: 1.7K
Y
Yuliang Zhao
H-index: 143 · Papers: 766
H
Huda Y. Zoghbi
H-index: 135 · Papers: 566
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