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Optimization of a DNA encoded library derived autotaxin inhibitor hit to a potent in vivo LPA lowering quinazolinone compound with a non-zinc binding mode Martin, Rainer E.; Satz, Alexander L.; Kuratli, Christoph; Hunziker, Daniel; Mattei, Patrizio; Hert, Jerome; Ullmer, Christoph; Rudolph, Markus G.; Alker, Andre M.; Hochstrasser, Remo; Marx, Andreas; Binder, Martin; Muller, Stephan Share Save
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ANG2 Blockade Diminishes Proangiogenic Cerebrovascular Defects Associated With Models of Hereditary Hemorrhagic Telangiectasia Zhou, Xingyan; Pucel, Jenna C.; Nomura-Kitabayashi, Aya; Chandakkar, Pallavi; Guidroz, Adella P.; Jhangiani, Nikita L.; Bao, Duran; Fan, Jia; Arthur, Helen M.; Ullmer, Christoph; Klein, Christian; Marambaud, Philippe; Meadows, Stryder M. Share Save
Platform Reagents Enable Synthesis of Ligand-Directed Covalent Probes: Study of Cannabinoid Receptor 2 in Live Cells Kosar, Miroslav; Sykes, David A.; Viray, Alexander E. G.; Vitale, Rosa Maria; Sarott, Roman C.; Ganzoni, Rudolf L.; Onion, David; Tobias, Janelle M.; Leippe, Philipp; Ullmer, Christoph; Zirwes, Elisabeth A.; Guba, Wolfgang; Grether, Uwe; Frank, James A.; Veprintsev, Dmitry B.; Carreira, Erick M. Share Save
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Elevated Levels of Growth/Differentiation Factor-15 in the Aqueous Humor and Serum of Glaucoma Patients Maddala, Rupalatha; Ho, Leona T. Y.; Karnam, Shruthi; Navarro, Iris; Osterwald, Anja; Stinnett, Sandra S.; Ullmer, Christoph; Vann, Robin R.; Challa, Pratap; Rao, Ponugoti V. Share Save
Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe Gazzi, Thais; Brennecke, Benjamin; Atz, Kenneth; Korn, Claudia; Sykes, David; Forn-Cuni, Gabriel; Pfaff, Patrick; Sarott, Roman C.; Westphal, Matthias, V; Mostinski, Yelena; Mach, Leonard; Wasinska-Kalwa, Malgorzata; Weise, Marie; Hoare, Bradley L.; Miljus, Tamara; Mexi, Maira; Roth, Nicolas; Koers, Eline J.; Guba, Wolfgang; Alker, Andre; Rufer, Arne C.; Kusznir, Eric A.; Huber, Sylwia; Raposo, Catarina; Zirwes, Elisabeth A.; Osterwald, Anja; Pavlovic, Anto; Moes, Svenja; Beck, Jennifer; Nettekoven, Matthias; Benito-Cuesta, Irene; Grande, Teresa; Drawnel, Faye; Widmer, Gabriella; Holzer, Daniela; van der Wel, Tom; Mandhair, Harpreet; Honer, Michael; Fingerle, Jurgen; Scheffel, Joerg; Broichhagen, Johannes; Gawrisch, Klaus; Romero, Julian; Hillard, Cecilia J.; Varga, Zoltan V.; van der Stelt, Mario; Pacher, Pal; Gertsch, Jurg; Ullmer, Christoph; McCormick, Peter J.; Oddi, Sergio; Spaink, Herman P.; Maccarrone, Mauro; Veprintsev, Dmitry B.; Carreira, Erick M.; Grether, Uwe; Nazare, Marc Share Save
TGR5 controls bile acid composition and gallbladder function to protect the liver from bile acid overload Bidault-Jourdainne, Valeska; Merlen, Gregory; Glenisson, Mathilde; Doignon, Isabelle; Garcin, Isabelle; Pean, Noemie; Boisgard, Raphael; Ursic-Bedoya, Jose; Serino, Matteo; Ullmer, Christoph; Humbert, Lydie; Abdelrafee, Ahmed; Golse, Nicolas; Vibert, Eric; Duclos-Vallee, Jean-Charles; Rainteau, Dominique; Tordjmann, Thierry Share Save
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Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells Sarott, Roman C.; Westphal, Matthias, V; Pfaff, Patrick; Korn, Claudia; Sykes, David A.; Gazzi, Thais; Brennecke, Benjamin; Atz, Kenneth; Weise, Marie; Mostinski, Yelena; Hompluem, Pattarin; Koers, Eline; Miljus, Tamara; Roth, Nicolas J.; Asmelash, Hermon; Vong, Man C.; Piovesan, Jacopo; Guba, Wolfgang; Rufer, Arne C.; Kusznir, Eric A.; Huber, Sylwia; Raposo, Catarina; Zirwes, Elisabeth A.; Osterwald, Anja; Pavlovic, Anto; Moes, Svenja; Beck, Jennifer; Benito-Cuesta, Irene; Grande, Teresa; de Martin Esteban, Samuel Ruiz; Yeliseev, Alexei; Drawnel, Faye; Widmer, Gabriella; Holzer, Daniela; van der Wel, Tom; Mandhair, Harpreet; Yuan, Cheng-Yin; Drobyski, William R.; Saroz, Yurii; Grimsey, Natasha; Honer, Michael; Fingerle, Juergen; Gawrisch, Klaus; Romero, Julian; Hillard, Cecilia J.; Varga, Zoltan V.; van der Stelt, Mario; Pacher, Pal; Gertsch, Juerg; McCormick, Peter J.; Ullmer, Christoph; Oddi, Sergio; Maccarrone, Mauro; Veprintsev, Dmitry B.; Nazare, Marc; Grether, Uwe; Carreira, Erick M. Share Save
Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors Haider, Ahmed; Gobbi, Luca; Kretz, Julian; Ullmer, Christoph; Brink, Andreas; Honer, Michael; Woltering, Thomas J.; Muri, Dieter; Iding, Hans; Burkler, Markus; Binder, Martin; Bartelmus, Christian; Knuesel, Irene; Pacher, Pal; Herde, Adrienne Mueller; Spinelli, Francesco; Ahmed, Hazem; Atz, Kenneth; Keller, Claudia; Weber, Markus; Schibli, Roger; Mu, Linjing; Grether, Uwe; Ametamey, Simon M. Share Save
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Highly Selective, Amine-Derived Cannabinoid Receptor 2 Probes Westphal, Matthias, V; Sarott, Roman C.; Zirwes, Elisabeth A.; Osterwald, Anja; Guba, Wolfgang; Ullmer, Christoph; Grether, Uwe; Carreira, Erick M. Share Save
Structure-Activity Relationship Studies of Pyridine-Based Ligands and Identification of a Fluorinated Derivative for Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors Haider, Ahmed; Kretz, Julian; Gobbi, Luca; Ahmed, Hazem; Atz, Kenneth; Burkler, Markus; Bartelmus, Christian; Fingerle, Jurgen; Guba, Wolfgang; Ullmer, Christoph; Honer, Michael; Knuesel, Irene; Weber, Markus; Brink, Andreas; Herde, Adrienne Mueller; Keller, Claudia; Schibli, Roger; Mu, Linjing; Grether, Uwe; Ametamey, Simon M. Share Save
Selective Cannabinoid 2 Receptor Agonists as Potential Therapeutic Drugs for the Treatment of Endotoxin-Induced Uveitis Porter, Richard Frederick; Szczesniak, Anna-Maria; Toguri, James Thomas; Gebremeskel, Simon; Johnston, Brent; Lehmann, Christian; Fingerle, Juergen; Rothenhaeusler, Benno; Perret, Camille; Rogers-Evans, Mark; Kimbara, Atsushi; Nettekoven, Matthias; Guba, Wolfgang; Grether, Uwe; Ullmer, Christoph; Kelly, Melanie E. M. Share Save
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