David Janzén - Publications, H-index & Citations

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David Janzén

AstraZeneca

18H-index

48Paper Count

1.0KCitation Count

Published Papers 12

Publication Date

No Evidence of QTc Interval Prolongation With Baxdrostat Treatment: Concentration–QTc Modeling Assessment

Pharmacology Research & Perspectives

IF2.3

2025-10-13

OAAI

Mikael Sunnåker; Christian Källgren; Joanna Parkinson; Corina Dota; Christer Gottfridsson; David Janzén; Anita Andersson; Glenn Carlson

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In PLN-R14del mice, SR structure restoration, rather than calcium cycling, is the dominant effector of PLN-ASO treatment

CARDIOVASCULAR RESEARCH

IF13.3

2025-09-01

OAAI

Sun, Liu; Eijgenraam, Tim R.; Amilon, Carl; Janzen, David; Hansson, Kenny M.; Kubli, Dieter A.; Spater, Daniela; Mullick, Adam E.; van der Meer, Peter; Teixeira, Vivian Oliveira Nunes; Sillje, Herman H. W.

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Preclinical Evaluation and First-In-Human Phase 1 Trial of AZD0186, a Novel, Oral Small Molecule Glucagon-Like Peptide-1 Receptor Agonist

pharmacology and experimental therapeutics

IF0

2025-08-28

OAAI

Weier Qi; Simina M. Boca; Alessandro Boianelli; Monica Fredberg; Sara Lundqvist; Graeme Davies; Joss Field; Cheryl A. Brighton; Arjan Snijder; Pernilla Grundevik; Daniel Eckernäs; Annika Maria Träff; Magnus Polla; Daniel Pettersen; Sami Omar; Lars Hansen; David Janzén; Johanna Melin; Natalie van Zuydam; Jennifer Logue; Kristina Wallenius

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Distribution and biotransformation of therapeutic antisense oligonucleotides and conjugates

DRUG DISCOVERY TODAY

IF7.5

2021-10-01

PREAI

Weidolf, Lars; Bjorkbom, Anders; Dahlen, Anders; Elebring, Marie; Gennemark, Peter; Holtta, Mikko; Janzen, David; Li, XueQing; Andersson, Shalini

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Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta Cell

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2021-02-24

PREAI

Knerr, Laurent; Prakash, Thazha P.; Lee, Richard; Drury, William J., III; Nikan, Mehran; Fu, Wuxia; Pirie, Elaine; De Maria, Leonardo; Valeur, Eric; Hayen, Ahlke; Olwegard-Halvarsson, Maria; Broddefalk, Johan; Ammala, Carina; Ostergaard, Michael E.; Meuller, Johan; Sundstrom, Linda; Andersson, Patrik; Janzen, David; Jansson-Lofmark, Rasmus; Seth, Punit P.; Andersson, Shalini

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In Vitro and In Vivo Evaluation of 3D Printed Capsules with Pressure Triggered Release Mechanism for Oral Peptide Delivery

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2021-01-01

OAAI

Berg, Staffan; Krause, Julius; Bjorkbom, Anders; Walter, Katrin; Harun, Said; Granfeldt, Andreas; Janzen, David; Nunes, Sandro Filipe; Antonsson, Malin; Van Zuydam, Natalie; Skrtic, Stanko; Hugerth, Andreas; Weitschies, Werner; Davies, Nigel; Abrahamsson, Bertil; Bergstrom, Christel A. S.

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Invalidation of GSK3B in Pancreatic Beta Cell as a Therapeutic Target for T2D

DIABETES

IF7.5

2020-06-01

PREAI

Murray, Sue; Zhang, Jiangwei; Ferng, Annie; Prakash, Thazha; Lee, Richard; Andersson, Eva-Marie; Janzen, David; Knerr, Laurent; Ammala, Carina; Guo, Shuling

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Model-Based Assessment of Variability in Isoniazid Pharmacokinetics and Metabolism in Patients Co-Infected With Tuberculosis and HIV: Implications for a Novel Dosing Strategy

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2020-03-02

OAAI

Sundell, Jesper; Bienvenu, Emile; Janzen, David; Birgersson, Sofia; Abelo, Angela; Ashton, Michael

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Three novel approaches to structural identifiability analysis in mixed-effects models

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

IF4.8

2019-04-01

PREAI

Janzen, David L., I; Jirstrand, Mats; Chappell, Michael J.; Evans, Neil D.

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Targeted delivery of antisense oligonucleotides to pancreatic β-cells

SCIENCE ADVANCES

IF12.5

2018-10-05

137

OAAI

Ammala, C.; Drury, W. J., III; Knerr, L.; Ahlstedt, I; Stillemark-Billton, P.; Wennberg-Huldt, C.; Andersson, E-M; Valeur, E.; Jansson-Lofmark, R.; Janzen, D.; Sundstrom, L.; Meuller, J.; Claesson, J.; Andersson, P.; Johansson, C.; Lee, R. G.; Prakash, T. P.; Seth, P. P.; Monia, B. P.; Andersson, S.

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Translational model to predict pulmonary pharmacokinetics and efficacy in man for inhaled bronchodilators

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY

IF3

2017-12-27

OAAI

Hendrickx, Ramon; Bergstrom, Eva Lamm; Janzen, David L. I.; Friden, Markus; Eriksson, Ulf; Grime, Ken; Ferguson, Douglas

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Parameter Identifiability of Fundamental Pharmacodynamic Models

Frontiers in Physiology

IF3.4

2016-12-05

OAAI

Janzen, David L. I.; Bergenholm, Linnea; Jirstrand, Mats; Parkinson, Joanna; Yates, James; Evans, Neil D.; Chappell, Michael J.

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Research Directions