Victor L. J. Tybulewicz - Publications, H-index & Citations

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Victor L. J. Tybulewicz

francis crick institute

87H-index

295Paper Count

3.0WCitation Count

Published Papers 108

Publication Date

C1q and immunoglobulins mediate activity-dependent synapse loss in the adult brain

Science

IF45.8

2026-07-09

PREAI

Gerard Crowley; Minjung Kim; Nathanael O’Neill; Emir Turkes; Fateme Ghasemi; Luca Giudice; Sebastiaan De Schepper; Benjy J. Y. Tan; Benito Maffei; Laís S. S. Ferreira; Julie Rebejac; Javier Rueda-Carrasco; Margarita Toneva; John Christian Fajardo; Judy Z. Ge; Zhengyue Grace Yang; Paula Korhonen; Phillip Muckett; Damaris Bennett; Camille Paoletti; Tammie T. M. Sow; David A. Posner; Annerieke Sierksma; Dimitra Sokolova; Viktoras Konstantellos; Leen Ali; Kiavash Movahedi; Andrew F. MacAskill; Victor L. J. Tybulewicz; Tarja Malm; Gabriele Lignani; Menna R. Clatworthy; Soyon Hong

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TACI regulates marginal zone B cell development

Journal of Experimental Medicine

IF10.6

2026-05-05

PREAI

Luff, Daisy H.; Vanes, Lesley; Boeing, Stefan; Tybulewicz, Victor L. J.

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Neuronal oscillations in cognition: Down syndrome as a model of mouse to human translation

NEUROSCIENTIST

IF3.9

2024-09-24

PREAI

Chang, Pishan; Perez-Gonzalez, Marta; Constable, Jessica; Bush, Daniel; Cleverley, Karen; Tybulewicz, Victor L. J.; Fisher, Elizabeth M. C.; Walker, Matthew C.

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Dissecting the contribution of human chromosome 21 syntenic regions to recognition memory processes in adult and aged mouse models of Down syndrome

FRONTIERS IN BEHAVIORAL NEUROSCIENCE

IF2.9

2024-07-10

OAAI

Canonica, Tara; Kidd, Emma J.; Gibbins, Dorota; Lana-Elola, Eva; Fisher, Elizabeth M. C.; Tybulewicz, Victor L. J.; Good, Mark

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Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2024-01-24

OAAI

Lana-Elola, Eva; Aoidi, Rifdat; Llorian, Miriam; Gibbins, Dorota; Buechsenschuetz, Callan; Bussi, Claudio; Flynn, Helen; Gilmore, Tegan; Watson-Scales, Sheona; Hansen, Marie Haugsten; Hayward, Darryl; Song, Ok-Ryul; Brault, Veronique; Herault, Yann; Deau, Emmanuel; Meijer, Laurent; Snijders, Ambrosius P.; Gutierrez, Maximiliano G.; Fisher, Elizabeth M. C.; Tybulewicz, Victor L. J.

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T cell migration requires ion and water influx to regulate actin polymerization

NATURE COMMUNICATIONS

IF15.7

2023-12-06

OAAI

de Boer, Leonard L.; Vanes, Lesley; Melgrati, Serena; O'May, Joshua Biggs; Hayward, Darryl; Driscoll, Paul C.; Day, Jason; Griffiths, Alexander; Magueta, Renata; Morrell, Alexander; MacRae, James I.; Kochl, Robert; Tybulewicz, Victor L. J.

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Investigating brain alterations in the Dp1Tyb mouse model of Down syndrome

NEUROBIOLOGY OF DISEASE

IF5.6

2023-11-01

OAAI

Serrano, Maria Elisa; Kim, Eugene; Siow, Bernard; Ma, Da; Rojo, Loreto; Simmons, Camilla; Hayward, Darryl; Gibbins, Dorota; Singh, Nisha; Strydom, Andre; Fisher, Elizabeth M. C.; Tybulewicz, Victor L. J.; Cash, Diana

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Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes

DEVELOPMENT

IF3.6

2023-04-26

OAAI

Redhead, Yushi; Gibbins, Dorota; Lana-Elola, Eva; Watson-Scales, Sheona; Dobson, Lisa; Krause, Matthias; Liu, Karen J.; Fisher, Elizabeth M. C.; Green, Jeremy B. A.; Tybulewicz, Victor L. J.

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Genetic dissection of triplicated chromosome 21 orthologs yields varying skeletal traits in Down syndrome model mice

DISEASE MODELS & MECHANISMS

IF3.3

2023-04-26

OAAI

Sloan, Kourtney; Thomas, Jared; Blackwell, Matthew; Voisard, Deanna; Lana-Elola, Eva; Watson-Scales, Sheona; Roper, Daniel L.; Wallace, Joseph M.; Fisher, Elizabeth M. C.; Tybulewicz, Victor L. J.; Roper, Randall J.

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B cell-intrinsic requirement for WNK1 kinase in antibody responses in mice

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2023-01-20

OAAI

Hayward, Darryl A.; Vanes, Lesley; Wissmann, Stefanie; Sivapatham, Sujana; Hartweger, Harald; O'May, Joshua Biggs; de Boer, Leonard L.; Mitter, Richard; Kochl, Robert; Stein, Jens, V; Tybulewicz, Victor L. J.

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Antidepressants cheer up hepatic B1 B cells: Hope for the treatment of autoimmune liver diseases?

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-01-17

OAAI

Amendt, Timm; Tybulewicz, Victor L. J.

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Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift

NATURE COMMUNICATIONS

IF15.7

2022-05-05

OAAI

Zhang, Yang; Garcia-Ibanez, Laura; Ulbricht, Carolin; Lok, Laurence S. C.; Pike, Jeremy A.; Mueller-Winkler, Jennifer; Dennison, Thomas W.; Ferdinand, John R.; Burnett, Cameron J. M.; Yam-Puc, Juan C.; Zhang, Lingling; Alfaro, Raul Maqueda; Takahama, Yousuke; Ohigashi, Izumi; Brown, Geoffrey; Kurosaki, Tomohiro; Tybulewicz, Victor L. J.; Rot, Antal; Hauser, Anja E.; Clatworthy, Menna R.; Toellner, Kai-Michael

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Eosinophils are an essential element of a type 2 immune axis that controls thymus regeneration

SCIENCE IMMUNOLOGY

IF16.3

2022-03-25

OAAI

Cosway, Emilie J.; White, Andrea J.; Parnell, Sonia M.; Schweighoffer, Edina; Jolin, Helen E.; Bacon, Andrea; Rodewald, Hans-Reimer; Tybulewicz, Victor; McKenzie, Andrew N. J.; Jenkinson, William E.; Anderson, Graham

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Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes

DISEASE MODELS & MECHANISMS

IF3.3

2021-10-18

OAAI

Lana-Elola, Eva; Cater, Heather; Watson-Scales, Sheona; Greenaway, Simon; Mueller-Winkler, Jennifer; Gibbins, Dorota; Nemes, Mihaela; Slender, Amy; Hough, Tertius; Keskivali-Bond, Piia; Scudamore, Cheryl L.; Herbert, Eleanor; Banks, Gareth T.; Mobbs, Helene; Canonica, Tara; Tosh, Justin; Noy, Suzanna; Llorian, Miriam; Nolan, Patrick M.; Griffin, Julian L.; Good, Mark; Simon, Michelle; Mallon, Ann-Marie; Wells, Sara; Fisher, Elizabeth M. C.; Tybulewicz, Victor L. J.

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BAFF signaling in health and disease

CURRENT OPINION IN IMMUNOLOGY

IF5.8

2021-08-01

OAAI

Schweighoffer, Edina; Tybulewicz, Victor L. J.

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Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis

NATURE COMMUNICATIONS

IF15.7

2021-07-27

OAAI

Mayes-Hopfinger, Lindsey; Enache, Aura; Xie, Jian; Huang, Chou-Long; Kochl, Robert; Tybulewicz, Victor L. J.; Fernandes-Alnemri, Teresa; Alnemri, Emad S.

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Maternal iron deficiency perturbs embryonic cardiovascular development in mice

NATURE COMMUNICATIONS

IF15.7

2021-06-08

OAAI

Kalisch-Smith, Jacinta I.; Ved, Nikita; Szumska, Dorota; Munro, Jacob; Troup, Michael; Harris, Shelley E.; Rodriguez-Caro, Helena; Jacquemot, Aimee; Miller, Jack J.; Stuart, Eleanor M.; Wolna, Magda; Hardman, Emily; Prin, Fabrice; Lana-Elola, Eva; Aoidi, Rifdat; Fisher, Elizabeth M. C.; Tybulewicz, Victor L. J.; Mohun, Timothy J.; Lakhal-Littleton, Samira; De Val, Sarah; Giannoulatou, Eleni; Sparrow, Duncan B.

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A landmark-free morphometrics pipeline for high-resolution phenotyping: application to a mouse model of Down syndrome

DEVELOPMENT

IF3.6

2021-03-12

OAAI

Toussaint, Nicolas; Redhead, Yushi; Vidal-Garcia, Marta; Lo Vercio, Lucas; Liu, Wei; Fisher, Elizabeth M. C.; Hallgrimsson, Benedikt; Tybulewicz, Victor L. J.; Schnabel, Julia A.; Green, Jeremy B. A.

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Critical requirement for BCR, BAFF, and BAFFR in memory B cell survival

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2020-10-29

OAAI

Mueller-Winkler, Jennifer; Mitter, Richard; Rappe, Julie C. F.; Vanes, Lesley; Schweighoffe, Edna; Mohammadi, Hamid; Wack, Andreas; Tybulewicz, Victor L. J.

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Critical role of WNK1 in MYC-dependent early mouse thymocyte development

ELIFE

IF0

2020-10-14

OAAI

Kochl, Robert; Vanes, Lesley; Sopena, Miriam Llorian; Chakravarty, Probir; Hartweger, Harald; Fountain, Kathryn; White, Andrea; Cowan, Jennifer; Anderson, Graham; Tybulewicz, Victor L. J.

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Research Directions