Arthur M. Mercurio - Publications, H-index & Citations

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Arthur M. Mercurio

University of Massachusetts Chan Medical School

81H-index

387Paper Count

2.1WCitation Count

Published Papers 103

Publication Date

Therapeutic delivery of albumin-binding siRNA targeting IRS2 to diverse cell types reduces mammary tumor growth

Molecular Therapy

IF12

2026-01-29

OAAI

Claire E. Tocheny; Julianna E. Buchwald; Christopher D. Dahlke; Hassan H. Fakih; Jennifer S. Morgan; Ashley Summers; Christi A. Silva; Samuel O. Jackson; Ji-Sun Lee; Michael-Anthony Card; Dimas Echeverria; Cornelia Peterson; Arthur M. Mercurio; Anastasia Khvorova; Leslie M. Shaw

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Inducing ferroptosis to impede metastasis by inhibiting the calcium channel TRPC6

Cell Reports

IF6.9

2025-11-08

OAAI

Boris S. Dimitrov; Dimpi Mukhopadhyay; Hira Lal Goel; Emmet R. Karner; Christi A. Silva; Ayush Kumar; Cornelia Peterson; Mengdie Wang; Arthur M. Mercurio

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Resistance to radiation enhances metastasis by altering RNA metabolism

Science Advances

IF12.5

2025-10-17

PREAI

Ayush Kumar; Kensei Kishimoto; Hira L. Goel; Christi A. Silva; Rui Li; Brendan Pacheco; Lihua J. Zhu; William A. Flavahan; Arthur M. Mercurio

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Targeting BRCA1-deficient PARP inhibitor-resistant cells with nickases reveals nick resection as a cancer vulnerability

NATURE CANCER

IF28.5

2025-01-21

PREAI

Whalen, Jenna M.; Earley, Jillian; Wisniewski, Christi; Mercurio, Arthur M.; Cantor, Sharon B.

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Therapeutic induction of ferroptosis in tumors using PD-L1 targeting antibody nanogel conjugates

CELL CHEMICAL BIOLOGY

IF7.2

2024-12-01

PREAI

Wang, Mengdie; Prachyathipsakul, Theeraphop; Wisniewski, Christi A.; Xiong, Choua; Goel, Shivam; Goel, Hira Lal; Karner, Emmet R.; Mukhopadhyay, Dimpi; Gupta, Prachi; Majee, Aniket; Thayumanavan, S.; Mercurio, Arthur M.

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HNRNPL-mediated mRNA stability underlies metastasis triggered by resistance to radiation therapy

MOLECULAR CANCER THERAPEUTICS

IF5.5

2024-11-14

PREAI

Kumar, Ayush; Kishimoto, Kensei; Wisniewski, Christi; Goel, Shivam; Mercurio, Arthur

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Neuropilin-2-expressing breast cancer cells mitigate radiation-induced oxidative stress through nitric oxide signaling

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2024-10-01

OAAI

Kumar, Ayush; Goel, Hira Lal; Wisniewski, Christi A.; Wang, Tao; Geng, Yansong; Wang, Mengdie; Goel, Shivam; Hu, Kai; Li, Rui; Zhu, Lihua J.; Clark, Jennifer L.; Ferreira, Lindsay M.; Brehm, Michael A.; FitzGerald, Thomas J.; Mercurio, Arthur M.

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YAP/TAZ-mediated regulation of laminin 332 is enabled by β 4 integrin repression of ZEB1 to promote ferroptosis resistance

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-04-01

OAAI

Goel, Hira Lal; Karner, Emmet R.; Kumar, Ayush; Mukhopadhyay, Dimpi; Goel, Shivam; Mercurio, Arthur M.

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The calcium channel TRPC6 promotes chemotherapy-induced persistence by regulating integrin α6 mRNA splicing

CELL REPORTS

IF6.9

2023-11-01

OAAI

Mukhopadhyay, Dimpi; Goel, Hira Lal; Xiong, Choua; Goel, Shivam; Kumar, Ayush; Li, Rui; Zhu, Lihua Julie; Clark, Jennifer L.; Brehm, Michael A.; Mercurio, Arthur M.

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Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple- negative breast cancer

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-05-03

OAAI

Xu, Zhiwen; Goel, Hira Lal; Burkart, Christoph; Burman, Luke; Chong, Yeeting E.; Barber, Alison G.; Geng, Yanyan; Zhai, Liting; Wang, Mengdie; Kumar, Ayush; Menefee, Ann; Polizzi, Clara; Eide, Lisa; Rauch, Kaitlyn; Rahman, Justin; Hamel, Kristina; Fogassy, Zachary; Klopp-Savino, Sofia; Paz, Suzanne; Zhang, Mingjie; Cubitt, Andrea; Nangle, Leslie A.; Mercurio, Arthur M.

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Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-05-03

PREAI

Wang, Mengdie; Wisniewski, Christi A.; Xiong, Choua; Chhoy, Peter; Goel, Hira Lal; Kumar, Ayush; Zhu, Lihua Julie; Li, Rui; St Louis, Pamela A.; Ferreira, Lindsay M.; Pakula, Hubert; Xu, Zhiwen; Loda, Massimo; Jiang, Zhong; Brehm, Michael A.; Mercurio, Arthur M.

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Protein kinase gat phosphorylation of specific serines in the connecting segment of the β4 integrin regulates the dynamics of type II hemidesmosomes

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Rabinovitz, I; Tsomo, L; Mercurio, AM

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Id2 Complexes with the SNAG Domain of Snai1 Inhibiting Snai1-Mediated Repression of Integrin β4

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Chang, Cheng; Yang, Xiaofang; Pursell, Bryan; Mercurio, Arthur M.

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PD-LI promotes rear retraction during persistent cell migration by altering integrin β4 dynamics

JOURNAL OF CELL BIOLOGY

IF6.4

2022-03-28

OAAI

Wang, Mengdie; Xiong, Choua; Mercurio, Arthur M.

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O-linked α2,3 sialylation defines stem cell populations in breast cancer

SCIENCE ADVANCES

IF12.5

2022-01-07

OAAI

Walker, Melanie R.; Goel, Hira Lal; Mukhopadhyay, Dimpi; Chhoy, Peter; Karner, Emmet R.; Clark, Jennifer L.; Liu, Haibo; Li, Rui; Zhu, Julie Lihua; Chen, Shuhui; Mahal, Lara K.; Bensing, Barbara A.; Mercurio, Arthur M.

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Targeting prominin2 transcription to overcome ferroptosis resistance in cancer

EMBO MOLECULAR MEDICINE

IF8.3

2021-07-05

OAAI

Brown, Caitlin W.; Chhoy, Peter; Mukhopadhyay, Dimpi; Karner, Emmet R.; Mercurio, Arthur M.

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Differentiation of Cancer Stem Cells through Nanoparticle Surface Engineering

ACS NANO

IF16

2020-11-09

OAAI

Geng, Yingying; Amante, John J.; Goel, Hira L.; Zhang, Xianzhi; Walker, Melanie R.; Luther, David C.; Mercurio, Arthur M.; Rotello, Vincent M.

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Domain-specific antibodies to Neuropilin 2 implicate VEGF-C and not Semaphorin 3F in breast cancer stem cell function

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Nangle, Leslie A.; Burman, Luke; Goel, Hira L.; Xu, Zhiwen; Hamel, Kristina; Bloom, Nathaniel; Mercurio, Arthur M.

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Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 Modulates Aggressiveness of Ewing Sarcoma by Regulating the CD164-CXCR4 Axis

FRONTIERS IN ONCOLOGY

IF3.3

2020-07-03

OAAI

Mancarella, Caterina; Caldoni, Giulia; Ribolsi, Irene; Parra, Alessandro; Manara, Maria Cristina; Mercurio, Arthur M.; Morrione, Andrea; Scotlandi, Katia

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Tumor cell-organized fibronectin maintenance of a dormant breast cancer population

SCIENCE ADVANCES

IF12.5

2020-03-13

OAAI

Barney, Lauren E.; Hall, Christopher L.; Schwartz, Alyssa D.; Parks, Akia N.; Sparages, Christopher; Galarza, Sualyneth; Platt, Manu O.; Mercurio, Arthur M.; Peyton, Shelly R.

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Research Directions