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J

Jan‐Bernd Funcke

University of Texas Southwestern Medical Center

22H-index
59Paper Count
2.2KCitation Count
Published Papers 32
Publication Date
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Non-enzymatic hepatic ABHD6 interacts with Akt-FoxO1 axis to regulate metabolic health
errNature Communications
IF15.7
err2026-08-03
err0
errOAAI
errGuannan Li; Laurence T. Maeyens; Jiyuan Yin; Jan-Bernd Funcke; Chanmin Joung; Ruizhen Li; Ziying Xu; Ting Wu; Xin Li; Nisi Jiang; Mbolle Ekane; Maria Paula Lopez; Pengju Cao; Sijia He; Adam B. Salmon; S. R. Murthy Madiraju; Marc Prentki; Juli Bai; James F. Nelson; Xianlin Han; Yi Zhu; Shangang Zhao
errShare
errSave
Adipocytes signal to recruit specific mRNAs from surrounding cells to restore expression deficits
errNature Communications
IF15.7
err2026-04-11
err0
errOAAI
errClair Crewe; Christy M. Gliniak; Toshiharu Onodera; Shiuhwei Chen; Jan-Bernd Funcke; May-Yun Wang; Snigdha Tiash; Yun-Ling Pai; Marjori Russo; Saket Awadhesbhai Patel; Ze Yu; Yi-Cian Zheng; Alex Larkin; Chao Xing; Laurent Gautron; Chun-Kan Chen; Chen Liu; Philipp E. Scherer
errShare
errSave
Neuronal GPR75 deficiency protects against diet-induced obesity in a humanized mouse model
errScience Advances
IF12.5
err2026-01-23
err0
errOAAI
errXue-Nan Sun; Jan-Bernd Funcke; Chanmin Joung; Chao Li; Ayanna Cobb; Toshiharu Onodera; Joselin Velasco; May-Yun Wang; Patrick Joseph Antonellis; Christopher Mazzone; Jared Senfeld; Minrong Ai; Philipp E. Scherer; Da Young Oh
errShare
errSave
Lipedema: a chronic adipose tissue disease
errTrends in Molecular Medicine
IF13.8
err2025-12-16
err0
PREAI
errJan-Bernd Funcke; Philipp E. Scherer; Leon G. Straub
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errSave
VCAM-1/Ezrin axis antagonizes myocardial damage in ischemia-reperfusion injury
errCell Death & Differentiation
IF0
err2025-11-28
err0
PREAI
errAnwarul Ferdous; Ariel Diaz; Daniel Daou; Diana Dad Zada; Nan Jiang; Herman I. May; Juan A. Daniel-Olivas; Jan-Bernd Funcke; Mayarling F. Troncoso; Jafet Ortiz-Quintero; Magda C. Diaz-Vesga; Lorena Garcia; Mario Chiong; Dian J. Cao; Thomas G. Gillette; Sergio Lavandero; Joseph A. Hill
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errSave
Induction of yin Yang 1 (YY1) overexpression in mature adipocytes promotes dysfunctional adipose tissue and systemic insulin resistance in mice
errMetabolism
IF3.7
err2025-11-19
err0
PREAI
errLine Pedersen; Christy M. Gliniak; Thomas Myhre Dale; Qingzhang Zhu; Chao Li; Jan-Bernd Funcke; Clair Crewe; Jiahui Luo; Lauren Palluth; Yi Zhu; Philipp E. Scherer
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errSave
ETP-specific-knockout mice reveal endotrophin as a key regulator of kidney fibrosis in ischemia–reperfusion injury models
errExperimental & Molecular Medicine
IF12.9
err2025-11-07
err0
errOAAI
errDae-Seok Kim; Jan-Bernd Funcke; Shiuhwei Chen; Kyounghee Min; Toshiharu Onodera; Min Kim; Qian Lin; Chanmin Joung; Joselin Velasco; Megan Virostek; Katarzyna Walendzik; Chitkale Hiremath; Denise K. Marciano; Philipp E. Scherer
errShare
errSave
Adipogenin promotes the development of lipid droplets by binding a dodecameric seipin complex
errScience
IF45.8
err2025-11-06
err0
PREAI
errChao Li; Xue-Nan Sun; Jan-Bernd Funcke; Lauri Vanharanta; Xavier Prasanna; Kaitlynn Gov; Yan Li; Megan Virostek; Chanmin Joung; Nolwenn Joffin; Kristiina Kanerva; Abel Szkalisity; Waldemar Kulig; Leon Straub; Shiuhwei Chen; Joselin Velasco; Ayanna Cobb; Davide La Padula; May-Yun Wang; Toshiharu Onodera; Csaba Vörös; Dae-Seok Kim; Min Kim; Oleg Varlamov; Yang Li; Chen Liu; Andrea R. Nawrocki; Shangang Zhao; Da Young Oh; Zhao V. Wang; Ruth Gordillo; Joel M. Goodman; R. Max Wynn; W. Mike Henne; Ilpo Vattulainen; Yan Han; Elina Ikonen; Philipp E. Scherer
errShare
errSave
Leptin as a key driver for organ fibrogenesis
errScience Advances
IF12.5
err2025-10-22
err0
PREAI
errXue-Nan Sun; Shiuhwei Chen; Shangang Zhao; Jan-Bernd Funcke; Megan Virostek; Line Pedersen; Chao Li; Chanmin Joung; Qian Lin; Yan Li; Ayanna Cobb; May-Yun Wang; Kyounghee Min; Lisandro Maya-Ramos; Giovanna Degasperi; Junquan Liu; Ningyan Zhang; Zhiqiang An; Diana R. Tomchick; R. Max Wynn; Da Young Oh; Philipp E. Scherer
errShare
errSave
Much ado about NAA-thing
errNature Metabolism
IF20.8
err2025-07-23
err0
PREAI
errJan-Bernd Funcke; Philipp E. Scherer
errShare
errSave
Defining lipedema's molecular hallmarks by multi-omics approach for disease prediction in women
errMETABOLISM-CLINICAL AND EXPERIMENTAL
IF11.9
err2025-03-01
err0
PREAI
errStraub, Leon G.; Funcke, Jan-Bernd; Joffin, Nolwenn; Joung, Chanmin; Al-Ghadban, Sara; Zhao, Shangang; Zhu, Qingzhang; Kruglikov, Ilja L.; Zhu, Yi; Langlais, Paul R.; Gordillo, Ruth; Herbst, Karen L.; Scherer, Philipp E.
errShare
errSave
The adiponectin-PPARg axis in hepatic stellate cells liver fibrosis
errCELL REPORTS
IF6.9
err2025-01-01
err0
errOAAI
errZhao, Shangang; Zhu, Qingzhang; Lee, Wang-Hsin; Funcke, Jan-Bernd; Zhang, Zhuzhen; Wang, May-Yun; Lin, Qian; Field, Bianca; Sun, Xue-Nan; Li, Guannan; Ekane, Mbolle; Onodera, Toshiharu; Li, Na; Zhu, Yi; Kusminski, Christine M.; Hinds, Terry D.; Scherer, Philipp E.
errShare
errSave
PAQR4 regulates adipocyte function and systemic metabolic health by mediating ceramide levels
errNATURE METABOLISM
IF20.8
err2024-07-03
err0
PREAI
errZhu, Qingzhang; Chen, Shiuhwei; Funcke, Jan-Bernd; Straub, Leon G.; Lin, Qian; Zhao, Shangang; Joung, Chanmin; Zhang, Zhuzhen; Kim, Dae-Seok; Li, Na; Gliniak, Christy M.; Lee, Charlotte; Cebrian-Serrano, Alberto; Pedersen, Line; Halberg, Nils; Gordillo, Ruth; Kusminski, Christine M.; Scherer, Philipp E.
errShare
errSave
Classification of Congenital Leptin Deficiency
errJOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
IF5.1
err2024-03-12
err2
errOAAI
errvon Schnurbein, Julia; Zorn, Stefanie; Nunziata, Adriana; Brandt, Stephanie; Moepps, Barbara; Funcke, Jan-Bernd; Hussain, Khalid; Farooqi, I. Sadaf; Fischer-Posovszky, Pamela; Wabitsch, Martin
errShare
errSave
Hyperleptinemia contributes to antipsychotic drug-associated obesity and metabolic disorders
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2023-11-22
err7
errOAAI
errZhao, Shangang; Lin, Qian; Xiong, Wei; Li, Li; Straub, Leon; Zhang, Dinghong; Zapata, Rizaldy; Zhu, Qingzhang; Sun, Xue-Nan; Zhang, Zhuzhen; Funcke, Jan-Bernd; Li, Chao; Chen, Shiuhwei; Zhu, Yi; Jiang, Nisi; Li, Guannan; Xu, Ziying; Wyler, Steven C.; Wang, May-Yun; Bai, Juli; Han, Xianlin; Kusminski, Christine M.; Zhang, Ningyan; An, Zhiqiang; Elmquist, Joel K.; Osborn, Olivia; Liu, Chen; Scherer, Philipp E.
errShare
errSave
Rare Antagonistic Leptin Variants and Severe, Early-Onset Obesity
errNEW ENGLAND JOURNAL OF MEDICINE
IF78.5
err2023-06-15
err14
errOAAI
errFuncke, Jan-Bernd; Moepps, Barbara; Roos, Julian; von Schnurbein, Julia; Verstraete, Kenneth; Froehlich-Reiterer, Elke; Kohlsdorf, Katja; Nunziata, Adriana; Brandt, Stephanie; Tsirigotaki, Alexandra; Dansercoer, Ann; Suppan, Elisabeth; Haris, Basma; Debatin, Klaus-Michael; Savvides, Savvas N.; Farooqi, I. Sadaf; Hussain, Khalid; Gierschik, Peter; Fischer-Posovszky, Pamela; Wabitsch, Martin
errShare
errSave
Adipose tissue macrophages exert systemic metabolic control by manipulating local iron concentrations
errNATURE METABOLISM
IF20.8
err2022-11-03
err36
PREAI
errJoffin, Nolwenn; Gliniak, Christy M.; Funcke, Jan-Bernd; Paschoal, Vivian A.; Crewe, Clair; Chen, Shiuhwei; Gordillo, Ruth; Kusminski, Christine M.; Oh, Da Young; Geldenhuys, Werner J.; Scherer, Philipp E.
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errSave
Deficient Caveolin-1 Synthesis in Adipocytes Stimulates Systemic Insulin-Independent Glucose Uptake via Extracellular Vesicles
errDIABETES
IF7.5
err2022-07-26
err6
errOAAI
errCrewe, Clair; Chen, Shiuhwei; Bu, Dawei; Gliniak, Christy M.; Asterholm, Ingrid Wernstedt; Yu, Xin Xin; Joffin, Nolwenn; de Souza, Camila O.; Funcke, Jan-Bernd; Oh, Da Young; Varlamov, Oleg; Robino, Jacob J.; Gordillo, Ruth; Scherer, Philipp E.
errShare
errSave
Activating Connexin43 gap junctions primes adipose tissue for therapeutic intervention
errACTA PHARMACEUTICA SINICA B
IF14.6
err2022-07-01
err4
errOAAI
errZhu, Yi; Li, Na; Huang, Mingyang; Chen, Xi; An, Yu A.; Li, Jianping; Zhao, Shangang; Funcke, Jan-Bernd; Cao, Jianhong; He, Zhenyan; Zhu, Qingzhang; Zhang, Zhuzhen; Wang, Zhao, V; Xu, Lin; Williams, Kevin W.; Li, Chien; Grove, Kevin; Scherer, Philipp E.
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errSave
Latent TGFβ-binding proteins regulate UCP1 expression and function via TGFβ2
errMOLECULAR METABOLISM
IF6.6
err2021-11-01
err14
errOAAI
errHalbgebauer, D.; Roos, J.; Funcke, J. B.; Neubauer, H.; Hamilton, B. S.; Simon, E.; Amri, E. Z.; Debatin, K. M.; Wabitsch, M.; Fischer-Posovszky, P.; Tews, D.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Philipp E. Scherer
H-index: 151 · Papers: 707
S
Samuel Klein
H-index: 121 · Papers: 543
J
Joel K. Elmquist
H-index: 116 · Papers: 365
J
Joseph A. Hill
H-index: 113 · Papers: 629
I
I. Sadaf Farooqi
H-index: 105 · Papers: 462
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