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S

Shaun R. Stauffer

cleveland clinic

45H-index
225Paper Count
6.6KCitation Count
Published Papers 65
Publication Date
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Virus-induced deconjugation of ISG15 dysregulates innate immunity and cellular metabolism
errImmunity
IF26.3
err2026-08-06
err0
PREAI
errJunji Zhu; GuanQun Liu; Jielin Xu; Zuberwasim Sayyad; Kun Li; Surajit Chakraborty; Christopher M. Goins; Huaxu Yu; Yadi Zhou; Shanti Ross; Evangeline White; Jun Zhao; Oliver Fiehn; Shaun R. Stauffer; Feixiong Cheng; Michaela U. Gack
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errSave
HMGB1 functions as a critical mediator of host defense at the gut mucosal barrier
errCell Host & Microbe
IF18.7
err2026-02-03
err0
errOAAI
errAnne-Marie C. Overstreet; McKenzie Burge; Brady Anderson; Xiaorong Zhu; Yun Tao; Candace M. Cham; Brenna Michaud; Soyar Horam; Naseer Sangwan; Mohammed Dwidar; Xuefeng Liu; Akeem Santos; Vartika Srivastava; Chelsea Finney; Christopher M. Goins; Zhanghan Dai; B. Ben Koff; Shaun R. Stauffer; Vanessa A. Leone; Jeannette S. Messer
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errSave
Fragment-Based Development of NSP14 Exonuclease Inhibitors Confounded by Batch-to-Batch Variability
errACS Chemical Biology
IF3.8
err2026-02-01
err0
errOAAI
errCoker, Jesse A.; Sun, Rong; Polzer, Paul M.; Romigh, Todd; Goins, Christopher M.; Wang, Nancy S.; Jung, Jae U.; Stauffer, Shaun R.
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errSave
The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programs
errNature Communications
IF15.7
err2025-11-14
err0
errOAAI
errTreg Grubb; Pooneh Koochaki; Sayed Matar; Fatme Ghandour; Marc Machaalani; Eddy Saad; Cerise Tang; Eduard Reznik; Jesminara Khatun; Carleigh Salem; Noah Dubasik; David A. Orlando; Matthew G. Guenther; Gyanu Parajuli; Raghvendra M. Srivastava; Steven R. Martinez; Jesse A. Coker; Ritesh R. Kotecha; A. Ari Hakimi; John M. Asara; Timothy A. Chan; Sakari Vanharanta; Shaun R. Stauffer; William G. Kaelin; Sabina Signoretti; Toni K. Choueiri; Abhishek A. Chakraborty
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errSave
The Same and Not the Same: Discovery of S-892216; A Second-Generation Nonpeptidic Covalent 3CL Protease Inhibitor for Oral COVID-19 Therapeutics
errJournal of Medicinal Chemistry
IF6.8
err2025-10-09
err0
PREAI
errShaun R. Stauffer
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errSave
The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programs
errONCOLOGIST
IF4.2
err2025-10-01
err0
errOAAI
errGrubb, Treg; Koochaki, Pooneh; Matar, Sayed; Ghandour, Fatme; Machaalani, Marc; Saad, Eddy; Tang, Cerise; Reznik, Eduard; Khatun, Jesminara; Salem, Carleigh; Dubasik, Noah; Orlando, David A.; Guenther, Matthew G.; Parajuli, Gyanu; Srivastava, Raghvendra M.; Martinez, Steven R.; Coker, Jesse; Kotecha, Ritesh; Hakimi, A. Ari; Asara, John; Chan, Timothy; Vanharanta, Sakari; Stauffer, Shaun; Kaelin, William G.; Signoretti, Sabina; Choueri, Toni; Chakraborty, Abhishek
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errSave
WD repeat domain 5 (WDR5) inhibitors: a patent review (2016-present)
errEXPERT OPINION ON THERAPEUTIC PATENTS
IF4.6
err2024-12-22
err0
PREAI
errCoker, Jesse A.; Stauffer, Shaun R.
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errSave
Discovery of VU0467319: an M1 Positive Allosteric Modulator Candidate That Advanced into Clinical Trials
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2024-12-11
err0
errOAAI
errPoslunsey, Michael S.; Wood, Michael R.; Han, Changho; Stauffer, Shaun R.; Panarese, Joseph D.; Melancon, Bruce J.; Engers, Julie L.; Dickerson, Jonathan W.; Peng, Weimin; Noetzel, Meredith J.; Cho, Hyekyung P.; Rodriguez, Alice L.; Hopkins, Corey R.; Morrison, Ryan; Crouch, Rachel D.; Bridges, Thomas M.; Blobaum, Anna L.; Boutaud, Olivier; Daniels, J. Scott; Kates, Michael J.; Castelhano, Arlindo; Rook, Jerri M.; Niswender, Colleen M.; Jones, Carrie K.; Conn, P. Jeffrey; Lindsley, Craig W.
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errSave
A Non-odorant Olfactory Receptor Ligand Depolymerizes the Platelet Actin Cytoskeleton to Prevent Thrombosis
errCIRCULATION
IF38.6
err2024-11-12
err0
PREAI
errAggarwal, Anu; Wang, Nancy; Josyula, Vara Prasad; Yang, Moua; Young, Shim; Kennedy, Quinn; Samuel, Reina; Sangwan, Naseer; Guntupalli, Suman; Godwin, Matthew; Ali, MAriya; Jennings, Courtney; Rajasekar, Bhairavi; Scalise, Alliefair; Stauffer, Shaun; McCrae, Keith; McIntyre, Thomas; Cameron, Scott
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errSave
ISGylation of the SARS-CoV-2 N protein by HERC5 impedes N oligomerization and thereby viral RNA synthesis
errJOURNAL OF VIROLOGY
IF3.8
err2024-09-17
err1
errOAAI
errZhu, Junji; Liu, GuanQun; Sayyad, Zuberwasim; Goins, Christopher M.; Stauffer, Shaun R.; Gack, Michaela U.
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errSave
Discovery and Characterization of Selective, First-in-Class Inhibitors of Citron Kinase
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-02-08
err1
PREAI
errMaw, Joshua J.; Coker, Jesse A.; Arya, Tarun; Goins, Christopher M.; Sonawane, Dhiraj; Han, Sang Hoon; Rees, Matthew G.; Ronan, Melissa M.; Roth, Jennifer A.; Wang, Nancy S.; Heemers, Hannelore V.; Macdonald, Jonathan D.; Stauffer, Shaun R.
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errSave
Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase
errCANCER RESEARCH
IF16.6
err2023-10-06
err4
errOAAI
errRawat, Chitra; Ben-Salem, Salma; Singh, Nidhi; Chauhan, Gaurav; Rabljenovic, Anja; Vaghela, Vishwa; Venkadakrishnan, Varadha Balaji; Macdonald, Jonathan D.; Dahiya, Ujjwal R.; Ghanem, Yara; Bachour, Salam; Su, Yixue; Depriest, Adam D.; Lee, Sanghee; Muldong, Michelle; Kim, Hyun-Tae; Kumari, Sangeeta; Valenzuela, Malyn May; Zhang, Dingxiao; Hu, Qiang; Cortes Gomez, Eduardo; Dehm, Scott M.; Zoubeidi, Amina; Jamieson, Christina A. M.; Nicolas, Marlo; Mckenney, Jesse; Willard, Belinda; Klein, Eric A.; Magi-Galluzzi, Cristina; Stauffer, Shaun R.; Liu, Song; Heemers, Hannelore V.
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errSave
BMX inhibition reverses HSD3B1-driven resistance in prostate cancer
errCANCER RESEARCH
IF16.6
err2023-06-02
err0
PREAI
errLi, Xiuxiu; Berk, Michael; Goins, Christopher; Alyamani, Mohammad; Chung, Yoon-Mi; Wang, Chenyao; Patel, Monaben; Rathi, Nityam; Zhu, Ziqi; Willard, Belinda; Stauffer, Shaun; Klein, Eric; Sharifi, Nima
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errSave
Citron kinase is a novel driver of prostate cancer progression and controls alternative splicing associated with treatment-resistance
errCANCER RESEARCH
IF16.6
err2023-06-02
err0
PREAI
errRawat, Chitra; Singh, Nidhi; Chauhan, Gaurav; Rabljenovic, Anja; Ben-Salem, Salma; Vaghela, Vishwa; Venkadakrishnan, Varadha B.; MacDonald, Jonathan; Dahiya, Ujjwal; DePriest, Adam D.; Lee, Sanghee; Muldong, Michelle; Kim, Hyun-Tae; Kumari, Sangeeta; Hu, Qiang; Cortes, Eduardo; Dehm, Scott M.; Zoubeidi, Amina; Jamieson, Christina A. M.; Nicolas, Marlo; McKenney, Jesse; Willard, Belinda; Klein, Eric A.; Magi-Galluzzi, Cristina; Stauffer, Shaun R.; Liu, Song; Heemers, Hannelore V.
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errSave
Identification Of A Molecule To Modulate A Platelet Olfactory Receptor And Limit Thrombosis
errARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
IF7.4
err2023-05-01
err0
PREAI
errAggarwal, Anu; Wang, Nancy; Prasad, Josyula V.; Jennings, Courtney; Godwin, Matthew; Bhandari, Rohan; Ali, Mariya; Stauffer, Shaun; Cameron, Scott J.
errShare
errSave
Leveraging Hot Spots of TEAD-Coregulator Interactions in the Design of Direct Small Molecule Protein-Protein Interaction Disruptors Targeting Hippo Pathway Signaling
errPHARMACEUTICALS
IF4.8
err2023-04-13
err9
errOAAI
errZhao, Bin; Pobbati, Ajaybabu. V. V.; Rubin, Brian. P. P.; Stauffer, Shaun
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errSave
Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer's disease (vol 1, pg 1175, 2021)
errNATURE AGING
IF19.4
err2023-03-20
err1
errOAAI
errFang, Jiansong; Zhang, Pengyue; Zhou, Yadi; Chiang, Chien-Wei; Tan, Juan; Hou, Yuan; Stauffer, Shaun; Li, Lang; Pieper, Andrew A. A.; Cummings, Jeffrey; Cheng, Feixiong
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errSave
BMX controls 3βHSD1 and sex steroid biosynthesis in cancer
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2023-01-17
err12
errOAAI
errLi, Xiuxiu; Berk, Michael; Goins, Christopher; Alyamani, Mohammad; Chung, Yoon-Mi; Wang, Chenyao; Patel, Monaben; Rathi, Nityam; Zhu, Ziqi; Willard, Belinda; Stauffer, Shaun; Klein, Eric; Sharifi, Nima
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errSave
Peripheral sTREM2-Related Inflammatory Activity Alterations in Early-Stage Alzheimer's Disease
errJOURNAL OF IMMUNOLOGY
IF3.4
err2022-05-15
err8
errOAAI
errWeber, Grace E.; Khrestian, Maria; Tuason, Elizabeth D.; Shao, Yvonne; Pillai, Jagan; Rao, Stephen; Feng, Hao; Zhou, Yadi; Cheng, Feixiong; DeSilva, Tara M.; Stauffer, Shaun; Leverenz, James B.; Bekris, Lynn M.
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errSave
Platelet olfactory receptor activation limits platelet reactivity and growth of aortic aneurysms
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2022-05-02
err20
errOAAI
errMorrell, Craig N.; Mix, Doran; Aggarwal, Anu; Bhandari, Rohan; Godwin, Matthew; Owens, Phillip; Lyden, Sean P.; Doyle, Adam; Krauel, Krystin; Rondina, Matthew T.; Mohan, Amy; Lowenstein, Charles J.; Shim, Sharon; Stauffer, Shaun; Josyula, Vara Prasad; Ture, Sara K.; Yule, David, I; Wagner, Larry E.; Ashton, John M.; Elbadawi, Ayman; Cameron, Scott J.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
J
Jeffrey L. Cummings
H-index: 176 · Papers: 1.5K
M
Marc G. Caron
H-index: 175 · Papers: 810
T
Toni K. Choueiri
H-index: 149 · Papers: 2.4K
W
William G. Kaelin
H-index: 138 · Papers: 491
T
Timothy A. Chan
H-index: 131 · Papers: 1.0K
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