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储炬 cover

储炬 (Ju Chu)

east china university of science and technology

46H-index
383Paper Count
7.3KCitation Count
Published Papers 183
Publication Date
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A Versatile tRNA-gRNA Array-Based CRISPR/Cas9 Platform Enabling Multiplex Genome Editing and Large-Fragment Engineering in Acremonium chrysogenum
errACS Synthetic Biology
IF3.9
err2026-04-29
err0
PREAI
errZhen Chen; Wei Hong; Xiaorong Wei; Yifan Li; Tao Feng; Xiang Ke; Xu Li; Yongming Wang; Haifeng Hang; Xiwei Tian; Ju Chu
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Soft-Sensing-Guided Glucose/l-Phenylalanine Cofeeding Strategy and Transcriptomic Analysis of the Optimal l-Phenylalanine Supply Range for Efficient β-Phenylethanol Biosynthesis in Saccharomyces cerevisiae
errJournal of Agricultural and Food Chemistry
IF6.2
err2026-03-18
err0
PREAI
errChenghan Yang; Huining Jia; Li Zhang; Hongrun Lan; Huyang Chen; Hao Bei; Ali Mohsin; Ju Chu; Haifeng Hang; Xiwei Tian; Yingping Zhuang
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Enhancing erythromycin production by Saccharopolyspora erythraea E3::sucBA in chemically defined medium
errBioresource Technology
IF9
err2025-11-27
err0
PREAI
errXiang Ke; Shuohan Wang; Xing Jiang; Xu Li; Ju Chu; Xiwei Tian
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Harnessing respiratory chain engineering enhances erythromycin production in Saccharopolyspora erythraea employing chemically defined medium
errChemical Engineering Journal
IF13.2
err2025-11-12
err0
PREAI
errXing Jiang; Yazhi Liu; Shuohan Wang; Xiang Ke; Qinghai Shang; Feng Li; Zhenhua Yu; Xu Li; Xiwei Tian; Ju Chu
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errSave
Enhancing Cephalosporin C Biosynthesis through a 2A Peptide-Based Multigene Coexpression System
errACS Synthetic Biology
IF3.9
err2025-10-23
err0
PREAI
errZhen Chen; Yifan Li; Xiaorong Wei; Wei Hong; Yuanxin Guo; Haifeng Hang; Ju Chu; Xiwei Tian
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Artificial intelligence-driven dynamic regulation for high-efficiency gentamicin C1a production
errGreen Chem.
IF9.2
err2025-10-06
err0
PREAI
errFeng Xu; Yuan Wang; Hao Gao; Kaihao Hu; Rong Ben; Ali Mohsin; Yuanxin Guo; Xu Li; Hui Wu; Haifeng Hang; Ju Chu; Xiwei Tian
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Application of Transcriptome Analysis for the Exploration of the Mechanism of Methionine Promoting the Synthesis of Cephalosporin C in Acremonium chrysogenum by Employing a Chemically Defined Medium
errfermentation
IF0
err2025-08-04
err0
errOAAI
errYifan Li; Zhen Chen; Wei Hong; Tao Feng; Xiwei Tian; Ju Chu
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errSave
Artificial intelligence-guided fermentation process regulation reveals metabolic rewiring in gentamicin C1a overproduction
errBioresource Technology
IF9
err2025-07-10
err0
PREAI
errFeng Xu; Lihuan Su; Yuan Wang; Hao Gao; Kaihao Hu; Rong Ben; Yuanxin Guo; Xu Li; Ju Chu; Xiwei Tian
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errSave
Harnessing near-infrared and Raman spectral sensing and artificial intelligence for real-time monitoring and precision control of bioprocess
errBIORESOURCE TECHNOLOGY
IF9
err2025-04-01
err0
PREAI
errXu, Feng; Su, Lihuan; Gao, Hao; Wang, Yuan; Ben, Rong; Hu, Kaihao; Mohsin, Ali; Li, Chao; Chu, Ju; Tian, Xiwei
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Constructing pyrG marker by CRISPR/Cas facilities the highly-efficient precise genome editing on industrial Aspergillus niger strain
errBIOPROCESS AND BIOSYSTEMS ENGINEERING
IF3.6
err2025-02-16
err0
PREAI
errSun, Jingchun; Jiang, Xing; Xu, Feng; Tian, Xiwei; Chu, Ju
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Alterations in Protein Phosphorylation and Arginine Biosynthesis Metabolism Confer β-Phenylethanol Tolerance in Saccharomyces cerevisiae
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2025-01-30
err0
PREAI
errYang, Chenghan; Ren, Yilin; Zhang, Li; Li, Yina; Wang, Chunxia; Hang, Haifeng; Tian, Xiwei; Mohsin, Ali; Chu, Ju; Zhuang, Yingping
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errSave
A Paradigm of Computer Vision and Deep Learning Empowers the Strain Screening and Bioprocess Detection
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2025-01-16
err0
errOAAI
errXu, Feng; Su, Lihuan; Wang, Yuan; Hu, Kaihao; Liu, Ling; Ben, Rong; Gao, Hao; Mohsin, Ali; Chu, Ju; Tian, Xiwei
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errSave
Succinylome Profiling the Function and Distribution of Lysine Succinylation in Saccharopolyspora erythraea
errAPPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
IF3.3
err2025-01-08
err0
errOAAI
errKe, Xiang; Jiang, Xing; Hussain, Muhammad Hammad; Tian, Xiwei; Chu, Ju
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Effect of catalase on CPC production during fermentation of Acremonium chrysogenum
errBIORESOURCES AND BIOPROCESSING
IF5.1
err2025-01-04
err0
errOAAI
errLiu, Ling; Chen, Zhen; Tian, Xiwei; Chu, Ju
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errSave
An industrial perspective on metabolic responses of Penicillium chrysogenum to periodic dissolved oxygen feast-famine cycles in a scale-down system
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2024-06-22
err2
PREAI
errWang, Xueting; Yang, Qi; Haringa, Cees; Wang, Zejian; Chu, Ju; Zhuang, Yingping; Wang, Guan
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errSave
A machine learning-based approach for improving plasmid DNA production in Escherichia coli fed-batch fermentations
errBIOTECHNOLOGY JOURNAL
IF3.1
err2024-06-19
err1
PREAI
errXu, Zhixian; Zhu, Xiaofeng; Mohsin, Ali; Guo, Jianfei; Zhuang, Yingping; Chu, Ju; Guo, Meijin; Wang, Guan
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errSave
Enhancing erythromycin production in Saccharopolyspora erythraea through rational engineering and fermentation refinement: A Design-Build-Test-Learn approach
errBIOTECHNOLOGY JOURNAL
IF3.1
err2024-05-26
err1
PREAI
errShao, Minghao; Xu, Feng; Ke, Xiang; Huang, Mingzhi; Chu, Ju
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errSave
Unveiling the mechanism of efficient β-phenylethyl alcohol conversion in wild-type Saccharomyces cerevisiae WY319 through multi-omics analysis
errBIOTECHNOLOGY JOURNAL
IF3.1
err2024-04-05
err5
PREAI
errYang, Chenghan; Ren, Yilin; Ge, Lihao; Xu, Wenting; Hang, Haifeng; Mohsin, Ali; Tian, Xiwei; Chu, Ju; Zhuang, Yingping
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errSave
Promoter screening and identification for metabolic regulation in Acremonium chrysogenum
errBIOTECHNOLOGY JOURNAL
IF3.1
err2024-03-13
err3
PREAI
errLiu, Ling; Li, Runge; Zhang, Xinrun; Chen, Zhen; Mohsin, Ali; Hang, Haifeng; Tian, Xiwei; Chu, Ju
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errSave
Enhancing and monitoring spore production in Clostridium butyricum using pH-based regulation strategy and a robust soft sensor based on back-propagation neural networks
errBIOTECHNOLOGY AND BIOENGINEERING
IF3.6
err2023-11-21
err4
PREAI
errXu, Feng; Zhang, Wenxiao; Wang, Yonghong; Tian, Xiwei; Chu, Ju
errShare
errSave

Research Directions

微生物代谢调控机制及代谢工程改造工业发酵过程优化与放大获奖工业发酵优化发酵过程生物反应器优化与放大2001年获上海市教委“曙光学者”2002年12月获教育部高等学校优秀骨干教师2003年3月获上海市三八红旗手2003年-2004年度上海市科学技术委员会技术预见专家2004年9月获上海市育才奖2004年度获“明治乳业生命科学奖”2006年获上海市教委“曙光跟踪计划”2006-2007年韩国Dong-A大学客座教授2010年10月获华东理工大学第二届“我心目中的良师益友”奖2011年博士生周进获上海市优秀博士论文专著工业发酵调控2006年（第二版）微生物发酵过程多尺度研究与优化其中为国外生化工程与生物技术进展系列丛书编写两章生物反应器与生物分离技术近期发表文章辅因子工程次级代谢重定向红霉素产量提升双组分系统基因铜稳态红霉素糖多胞菌A-Factor类似物比特必霉素生物合成质谱代谢组学采样方案优化链霉菌代谢组学聚酮合酶在头孢霉素生物合成中的作用代谢组学动态变化杀念菌素生物合成基因簇表达多效调控因子AdpA链霉菌高产槐糖脂筛选系统甘油和葡萄糖共利用能力抗生素生物合成发酵工程多组学整合分析基因组规模代谢模型模拟黑曲霉工业酶生产细胞适应性葡萄糖氧化酶高产筛选代谢结构动力学模型青霉菌生长与产物形成动力学青霉素发酵过程系统分析黑曲霉基因组代谢网络模型红霉素生产速率丙酰辅酶A池代谢组学分析红霉素发酵过程优化乳酸发酵代谢组学葡萄糖酸生产实时监测在线生理参数氧化还原环境对L-乳酸生产的影响13C代谢通量分析黑曲霉葡萄糖淀粉酶生产葡萄糖淀粉酶生产优化搅拌桨与传质研究真菌特性对种子形态和剪切应力的依赖性生物反应器高通量筛选葡萄糖酸高产菌株黑曲霉葡萄糖呼吸商反馈控制红霉素生产重组菌株放大培养微生物动力学与流体动力学整合工业生物过程模型驱动放大高通量筛选红曲霉高产色素菌株氮磷动态调控红霉素发酵重组红霉素糖多孢菌氧传质效率环境渗透压响应L-乳酸生产效率青霉素生产螺旋霉素I厌氧消化代谢红霉素高通量筛选铵硫酸和磷酸动态调控头孢菌素C高产菌株筛选S-腺苷甲硫氨酸生产头孢菌素C生产发酵放大流体动力学异源蛋白表达蛋白二硫键构象氧气摄取速率调控阿维菌素B1a分批发酵毕赤酵母高密度培养重组人共识干扰素突变体生产: 3600-3608高通量筛选工程型组成型启动子毕赤酵母: 3360-3365种子质量对重组产红霉素糖多孢菌产量的评估: 1119-1129定量代谢通量分析产黄顶头孢霉豆油: 959-968重组红色糖多孢菌发酵优化产业化红霉素A生产补料分批发酵氧摄取速率控制策略阿维菌素B-1a生产工业规模发酵响应面法优化红霉素分批发酵生产氧摄取率优化氮调控规模放大:3358-3365红霉素A生产强化氮源喂养工业生物过程控制与优化系统生物技术纤维素酶优化生物质转化异戊酰螺旋霉素组分改善双醋螺旋霉素生产蛋氨酸腺苷转移酶基因DNA改组毕赤酵母S-腺苷甲硫氨酸生产红霉素发酵代谢工程授权专利蚯蚓纤溶酶发酵生产S-腺苷甲硫氨酸S-腺苷甲硫氨酸生产菌株构建大规模发酵铵离子调控林可霉素发酵过程提高林可霉素产量
Co-authors
Cooperation Journals
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周震 (Zhen Zhou)
H-index: 122 · Papers: 830
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张立欣 (Lixin Zhang)
H-index: 104 · Papers: 1.2K
朱为宏 cover
朱为宏 (Weihong Zhu)
H-index: 97 · Papers: 559
刘
刘东红 (Donghong Liu)
H-index: 87 · Papers: 674
J
Joseph J. Heijnen
H-index: 87 · Papers: 542
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