John van der Oost - Publications, H-index & Citations

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John van der Oost

wageningen university

95H-index

534Paper Count

4.8WCitation Count

Published Papers 197

Publication Date

A modular all-in-one genetic engineering tool for the diatom Phaeodactylum tricornutum based on CRISPR-Cas12a

Trends in Biotechnology

IF14.9

2026-06-17

OAAI

Nicola Trevisan; Christina Zotou; Rodrigo M. Martins; John van der Oost; Maria J. Barbosa; Sarah D’Adamo

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Molecular basis for methylation-sensitive editing by Cas9

Nature

IF48.5

2026-04-15

OAAI

Mitchell O. Roth; Yuerong Shu; Yu Zhao; Despoina Trasanidou; Renee D. Hoffman; Christian Südfeld; Eugenios Bouzetos; Nikolaos Trasanidis; Michael Zawrotny; Mary K. Gelasco; Megan L. Medina; Anuska Das; Jay Rai; Hemant N. Goswami; Bing Wang; John van der Oost; Hong Li

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The genome editing revolution

Trends in Biotechnology

IF14.9

2026-04-03

PREAI

John van der Oost; Constantinos Patinios

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Base editing both DNA strands in distinct editing windows with small CRISPR-associated effector Cas12f1

iScience

IF4.1

2025-11-12

OAAI

Thomas Swartjes; Evgenios Bouzetos; Belén Adiego-Pérez; Victor D. Pool; Raymond H.J. Staals; John van der Oost; Wen Y. Wu

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An updated evolutionary classification of CRISPR–Cas systems including rare variants

Nature Microbiology

IF19.4

2025-11-06

OAAI

Kira S. Makarova; Sergey A. Shmakov; Yuri I. Wolf; Pascal Mutz; Han Altae-Tran; Chase L. Beisel; Stan J. J. Brouns; Emmanuelle Charpentier; David Cheng; Jennifer Doudna; Daniel H. Haft; Philippe Horvath; Sylvain Moineau; Francisco J. M. Mojica; Patrick Pausch; Rafael Pinilla-Redondo; Shiraz A. Shah; Virginijus Siksnys; Michael P. Terns; Jesse Tordoff; Česlovas Venclovas; Malcolm F. White; Alexander F. Yakunin; Feng Zhang; Roger A. Garrett; Rolf Backofen; John van der Oost; Rodolphe Barrangou; Eugene V. Koonin

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Heterologous production of β-pinene in the chloroplast of the marine diatom Phaeodactylum tricornutum

New Biotechnology

IF4.9

2025-10-08

OAAI

Nicola Trevisan; Michele Fabris; John van der Oost; Maria Barbosa; Sarah D’Adamo

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Cell-free screening of CRISPR-Cas activity by microfluidics-assisted in vitro compartmentalization

Trends in Biotechnology

IF14.9

2025-08-14

OAAI

Evgenios Bouzetos; Ketan Ashok Ganar; John van der Oost; Siddharth Deshpande

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Biology and applications of CRISPR-Cas12 and transposon-associated homologs

NATURE BIOTECHNOLOGY

IF41.7

2024-12-04

PREAI

Wu, Wen Y.; Adiego-Perez, Belen; van der Oost, John

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Characterization of the AcrIIC1 anti-CRISPR protein for Cas9-based genome engineering in E. coli

COMMUNICATIONS BIOLOGY

IF5.1

2023-10-13

OAAI

Trasanidou, Despoina; Potocnik, Ana; Barendse, Patrick; Mohanraju, Prarthana; Bouzetos, Evgenios; Karpouzis, Efthymios; Desmet, Amber; van Kranenburg, Richard; van der Oost, John; Staals, Raymond H. J.; Mougiakos, Ioannis

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Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2023-07-17

OAAI

Omura, Satoshi N.; Nakagawa, Ryoya; Sudfeld, Christian; Warren, Ricardo Villegas; Wu, Wen Y.; Hirano, Hisato; Laffeber, Charlie; Kusakizako, Tsukasa; Kise, Yoshiaki; Lebbink, Joyce H. G.; Itoh, Yuzuru; van der Oost, John; Nureki, Osamu

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Multiplex genome engineering in Clostridium beijerinckii NCIMB 8052 using CRISPR-Cas12a

SCIENTIFIC REPORTS

IF3.9

2023-06-22

OAAI

Patinios, Constantinos; de Vries, Stijn T.; Diallo, Mamou; Lanza, Lucrezia; Verbrugge, Pepijn L. J. V. Q.; Lopez-Contreras, Ana M.; van der Oost, John; Weusthuis, Ruud A.; Kengen, Serve W. M.

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Efficient Genome and Base Editing in Human Cells Using ThermoCas9

CRISPR JOURNAL

IF4

2023-06-01

PREAI

Trasanidou, Despoina; Barendse, Patrick; Bouzetos, Evgenios; de Haan, Laura; Bouwmeester, Hans; Staals, Raymond H. J.; Mougiakos, Ioannis; van der Oost, John

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The genome editing revolution

TRENDS IN BIOTECHNOLOGY

IF14.9

2023-03-01

OAAI

Van der Oost, John; Patinios, Constantinos

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Revealing determinants of translation efficiency via whole-gene codon randomization and machine learning

NUCLEIC ACIDS RESEARCH

IF13.1

2023-01-31

OAAI

Nieuwkoop, Thijs; Terlouw, Barbara R.; Stevens, Katherine G.; Scheltema, Richard A.; de Ridder, Dick; van der Oost, John; Claassens, Nico J.

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Compact but mighty: Biology and applications of type III-E CRISPR-Cas systems

MOLECULAR CELL

IF16.6

2022-12-01

OAAI

Steens, Jurre A.; van der Oost, John; Staals, Raymond H. J.

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The miniature CRISPR-Cas12m effector binds DNA to block transcription

MOLECULAR CELL

IF16.6

2022-12-01

OAAI

Wu, Wen Y.; Mohanraju, Prarthana; Liao, Chunyu; Adiego-Perez, Belen; Creutzburg, Sjoerd C. A.; Makarova, Kira S.; Keessen, Karlijn; Lindeboom, Timon A.; Khan, Tahseen S.; Prinsen, Stijn; Joosten, Rob; Yan, Winston X.; Migur, Anzhela; Laffeber, Charlie; Scott, David A.; Lebbink, Joyce H. G.; Koonin, Eugene, V; Beisel, Chase L.; van der Oost, John

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The double life of CRISPR-Cas13

CURRENT OPINION IN BIOTECHNOLOGY

IF7

2022-12-01

PREAI

Bot, Jorik F.; van der Oost, John; Geijsen, Niels

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Metabolic engineering of Clostridium autoethanogenum for ethyl acetate production from CO

MICROBIAL CELL FACTORIES

IF4.9

2022-11-23

OAAI

Dykstra, James C.; van Oort, Jelle; Yazdi, Ali Tafazoli; Vossen, Eric; Patinios, Constantinos; van der Oost, John; Sousa, Diana Z.; Kengen, Serve W. M.

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Comparative Metagenomic Analysis of Biosynthetic Diversity across Sponge Microbiomes Highlights Metabolic Novelty, Conservation, and Diversification

MSYSTEMS

IF4.6

2022-08-30

OAAI

Loureiro, Catarina; Galani, Anastasia; Gavriilidou, Asimenia; de Mares, Maryam Chaib; van der Oost, John; Medema, Marnix H.; Sipkema, Detmer

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Adaptation by Type V-A and V-B CRISPR-Cas Systems Demonstrates Conserved Protospacer Selection Mechanisms Between Diverse CRISPR-Cas Types

CRISPR JOURNAL

IF4

2022-08-01

OAAI

Wu, Wen Y.; Jackson, Simon A.; Almendros, Cristobal; Haagsma, Anna C.; Yilmaz, Suzan; Gort, Gerrit; van der Oost, John; Brouns, Stan J. J.; Staals, Raymond H. J.

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Research Directions