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J

Javier Fernández‐Ruíz

universidad complutense

82H-index
344Paper Count
2.1WCitation Count
Published Papers 118
Publication Date
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Defining the Intestinal eCBome and Oxylipin Signaling Systems in a TDP-43 Mouse Model of Frontotemporal Dementia
errthe faseb journal
IF0
err2026-01-12
err0
errOAAI
errHayatte-Dounia Mir; Giada Giorgini; Irene Santos-García; Elizabeth Dumais; Carmen Rodríguez-Cueto; Eva de Lago; Cristoforo Silvestri; Nicolas Flamand; Javier Fernández-Ruiz; Vincenzo Di Marzo
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Assessment of the therapeutic effect of IGS2.7, a CK1δ protein kinase inhibitor, in combination with riluzole for the treatment of ALS-associated TDP-43 proteinopathy
errNeuropharmacology
IF4.6
err2025-12-11
err0
errOAAI
errMarta Gomez-Almeria; Loreto Martinez-Gonzalez; Ana Teresa Matos; Carmen Rodriguez-Cueto; Ana Rita Vaz; Raquel Martín-Baquero; Carmen Pérez de la Lastra; Rafael Infantes; Javier Fernández-Ruiz; Valle Palomo; Carmen Gil; Dora Brites; Ana Martinez; Eva de Lago
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Relevance of a peripheral site of action outside the brain-blood barrier for the beneficial effects of CB2 receptor activation in experimental ALS in male mice
errCell Communication and Signaling
IF8.9
err2025-10-12
err0
errOAAI
errMarta Gómez-Almería; Claudia Gonzalo-Consuegra; Carmen Rodríguez-Cueto; María Cabañas-Cotillas; Alberto Jiménez-Amor; Isabel Machín-Díaz; Matthias B. Wittwer; Pawel Dzygiel; Diego Clemente; Uwe Grether; Javier Fernández-Ruiz; Eva de Lago
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Preclinical evaluation of cannabidiolic acid as a neuroprotective agent in TDP-43 transgenic mice, an experimental model of amyotrophic lateral sclerosis
errBiomedicine & Pharmacotherapy
IF7.5
err2025-06-27
err0
PREAI
errLaura García-Toscano; Carmen Rodríguez-Cueto; Anna Furiano; William Hind; Eva de Lago; Javier Fernández-Ruiz
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Investigation in the CB1 and CB2 receptor binding profile and intrinsic activity of (-) and (+)-enantiomers of some naturally occurring phytocannabinoids or synthetic derivatives
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY REPORTS
IF4.1
err2025-06-11
err0
errOAAI
errSantiago Rodríguez-Carreiro; María Gómez-Cañas; Francesca Lubrini; Claudia Gonzalo-Consuegra; Matthias Winkler; Diego Caprioglio; Giovanni Appendino; Concepción García; Paula Morales; Nadine Jagerovic; Joerg T. Fischer; Bernd L. Fiebich; Marcus R. Goetz; Eduardo Muñoz; Javier Fernández-Ruiz
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Investigation in blood-brain barrier integrity and susceptibility to immune cell penetration in a mouse model of Dravet syndrome
errbrain behavior and immunity
IF3.5
err2025-03-01
err0
errOAAI
errAlonso, Cristina; Garcia-Culebras, Alicia; Satta, Valentina; Hernandez-Fisac, Ines; Sierra, Alvaro; Guimare, Jose A.; Lizasoain, Ignacio; Fernandez-Ruiz, Javier; Sagredo, Onintza
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Involvement of CB 1 and CB 2 receptors in neuroprotective effects of cannabinoids in experimental TDP-43 related frontotemporal dementia using male mice
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2024-05-01
err1
errOAAI
errGonzalo-Consuegra, Claudia; Santos-Garcia, Irene; Garcia-Toscano, Laura; Martin-Baquero, Raquel; Rodriguez-Cueto, Carmen; Wittwer, Matthias B.; Dzygiel, Pawel; Grether, Uwe; de Lago, Eva; Fernandez-Ruiz, Javier
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From Alzheimer's disease to vascular dementia: Different roads leading to cognitive decline
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2024-01-10
err0
errOAAI
errSemerano, Aurora; Fernandez-Ruiz, Javier; Cortes-Canteli, Marta; Moro, Maria A.
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Preclinical investigation in FAAH inhibition as a neuroprotective therapy for frontotemporal dementia using TDP-43 transgenic male mice
errJOURNAL OF NEUROINFLAMMATION
IF10.1
err2023-05-06
err3
errOAAI
errSantos-Garcia, Irene; Rodriguez-Cueto, Carmen; Villegas, Patricia; Piscitelli, Fabiana; Lauritano, Anna; Shen, Che-Kun J.; Di Marzo, Vincenzo; Fernandez-Ruiz, Javier; de Lago, Eva
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Thienopyrimidine Derivatives as GPR55 Receptor Antagonists: Insight into Structure-Activity Relationship
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2022-12-02
err2
errOAAI
errFiguerola-Asencio, Laura; Morales, Paula; Zhao, Pingwei; Hurst, Dow P.; Sayed, Sommayah S.; Colon, Katsuya L.; Gomez-Canas, Maria; Fernandez-Ruiz, Javier; Croatt, Mitchell P.; Reggio, Patricia H.; Abood, Mary E.; Jagerovic, Nadine
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Preclinical Investigation in Neuroprotective Effects of the GPR55 Ligand VCE-006.1 in Experimental Models of Parkinson's Disease and Amyotrophic Lateral Sclerosis
errMOLECULES
IF4.6
err2021-12-16
err14
errOAAI
errBurgaz, Sonia; Garcia, Concepcion; Gonzalo-Consuegra, Claudia; Gomez-Almeria, Marta; Ruiz-Pino, Francisco; Unciti, Juan Diego; Gomez-Canas, Maria; Alcalde, Juan; Morales, Paula; Jagerovic, Nadine; Rodriguez-Cueto, Carmen; de Lago, Eva; Munoz, Eduardo; Fernandez-Ruiz, Javier
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Effect of a combination therapy with cannabidiol and β-caryophyllene in SCN1A-A1783V mice, an experimental model of dravet syndrome
errEUROPEAN NEUROPSYCHOPHARMACOLOGY
IF6.7
err2021-12-01
err0
PREAI
errAlonso Gomez, C.; Satta, V.; Hernandez Fisac, I.; Fernandez Ruiz, J.; Sagredo Ezkioga, O.
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(+)-trans-Cannabidiol-2-hydroxy pentyl is a dual CB1R antagonist/CB2R agonist that prevents diabetic nephropathy in mice
errPHARMACOLOGICAL RESEARCH
IF10.5
err2021-07-01
err14
PREAI
errGonzalez-Mariscal, Isabel; Carmona-Hidalgo, Beatriz; Winkler, Matthias; Unciti-Broceta, Juan D.; Escamilla, Alejandro; Gomez-Canas, Maria; Fernandez-Ruiz, Javier; Fiebich, Bernd L.; Romero-Zerbo, Silvana-Yanina; Bermudez-Silva, Francisco J.; Collado, Juan A.; Munoz, Eduardo
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Neuroprotection with the Cannabidiol Quinone Derivative VCE-004.8 (EHP-101) against 6-Hydroxydopamine in Cell and Murine Models of Parkinson's Disease
errMOLECULES
IF4.6
err2021-05-28
err18
errOAAI
errBurgaz, Sonia; Garcia, Concepcion; Gomez-Canas, Maria; Rolland, Alain; Munoz, Eduardo; Fernandez-Ruiz, Javier
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Cannabinoid receptor CB2 ablation protects against TAU induced neurodegeneration
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2021-05-17
err22
errOAAI
errGalan-Ganga, M.; Rodriguez-Cueto, C.; Merchan-Rubira, J.; Hernandez, F.; avila, J.; Posada-Ayala, M.; Lanciego, J. L.; Luengo, E.; Lopez, M. G.; Rabano, A.; Fernandez-Ruiz, J.; Lastres-Becker, I.
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Inactivation of the CB2 receptor accelerated the neuropathological deterioration in TDP-43 transgenic mice, a model of amyotrophic lateral sclerosis
errBRAIN PATHOLOGY
IF6.2
err2021-05-13
err15
errOAAI
errRodriguez-Cueto, Carmen; Gomez-Almeria, Marta; Garcia Toscano, Laura; Romero, Julian; Hillard, Cecilia J.; de Lago, Eva; Fernandez-Ruiz, Javier
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Analogues of cannabinoids as multitarget drugs in the treatment of Alzheimer's disease
errEUROPEAN JOURNAL OF PHARMACOLOGY
IF4.7
err2021-03-01
err10
errOAAI
errSanchez Montero, Jose Maria; Agis-Torres, Angel; Solano, David; Sollhuber, Monica; Fernandez, Maria; Villaro, Wilma; Gomez-Canas, Maria; Garcia-Arencibia, Moises; Fernandez-Ruiz, Javier; Egea, Javier; Isabel Martin, Maria; Giron, Rocio
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Recent advances in the pathogenesis and therapeutics of amyotrophic lateral sclerosis
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2021-02-27
err5
errOAAI
errFernandez-Ruiz, Javier; de Lago, Eva; Rodriguez-Cueto, Carmen; Moro, Maria A.
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Targeting the CB2 receptor and other endocannabinoid elements to delay disease progression in amyotrophic lateral sclerosis
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2021-02-20
err15
PREAI
errRodriguez-Cueto, Carmen; Garcia-Toscano, Laura; Santos-Garcia, Irene; Gomez-Almeria, Marta; Gonzalo-Consuegra, Claudia; Espejo-Porras, Francisco; Fernandez-Ruiz, Javier; de Lago, Eva
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Discovery of Homobivalent Bitopic Ligands of the Cannabinoid CB2 Receptor**
errCHEMISTRY-A EUROPEAN JOURNAL
IF3.7
err2020-11-09
err20
errOAAI
errMorales, Paula; Navarro, Gemma; Gomez-Autet, Marc; Redondo, Laura; Fernandez-Ruiz, Javier; Perez-Benito, Laura; Cordomi, Arnau; Pardo, Leonardo; Franco, Rafael; Jagerovic, Nadine
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Research Directions

No research directions
Co-authors
Cooperation Journals
V
Vincenzo Di Marzo
H-index: 158 · Papers: 1.2K
O
Orrin Devinsky
H-index: 121 · Papers: 1.2K
I
Isidró Ferrer
H-index: 119 · Papers: 1.2K
R
Raphael Mechoulam
H-index: 116 · Papers: 563
J
Jesús Ávila
H-index: 108 · Papers: 852
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