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First Sustainable One-Pot Tandem Hantzsch Multicomponent Reaction/Click Reaction Approach for Novel Multitarget-Directed Ligands in Alzheimer's Disease Bernard, Paul J.; Wieckowska, Anna; Grosjean, Sylvain; Godyn, Justyna; Salat, Kinga; Detka, Jan; Palacz, Natalia; Tyrybon, Weronika; Jonczyk, Jakub; Szalaj, Natalia; Zareba, Paula; Martin, Helene; Maj, Maciej; Jozwiak, Krzysztof; Marco-Contelles, Jose; Ismaili, Lhassane Share Save
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Discovery of New Highly Potent Histamine H3 Receptor Antagonists, Calcium Channel Blockers, and Acetylcholinesterase Inhibitors Malek, Rim; Salat, Kinga; Totoson, Perle; Karcz, Tadeusz; Refouvelet, Bernard; Skrzypczak-Wiercioch, Anna; Maj, Maciej; Simakov, Alexey; Martin, Helene; Siwek, Agata; Szalaj, Natalia; Godyn, Justyna; Panek, Dawid; Wieckowska, Anna; Jozwiak, Krzysztof; Demougeot, Celine; Kiec-Kononowicz, Katarzyna; Chabchoub, Fakher; Iriepa, Isabel; Marco-Contelles, Jose; Ismaili, Lhassane Share Save
Design and Synthesis of Multi-Functional Ligands through Hantzsch Reaction: Targeting Ca2+ Channels, Activating Nrf2 and Possessing Cathepsin S Inhibitory, and Antioxidant Properties Pachon-Angona, Irene; Bernard, Paul J.; Simakov, Alexey; Maj, Maciej; Jozwiak, Krzysztof; Novotna, Anna; Lemke, Carina; Guetschow, Michael; Martin, Helene; Oset-Gasque, Maria-Jesus; Contelles, Jose-Marco; Ismaili, Lhassane Share Save
Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, β-secretase, and amyloid β aggregation as potential treatment of Alzheimer's disease Zareba, Paula; Latka, Kamil; Mazur, Gabriela; Gryzlo, Beata; Pasieka, Anna; Godyn, Justyna; Panek, Dawid; Skrzypczak-Wiercioch, Anna; Hoefner, Georg C.; Latacz, Gniewomir; Maj, Maciej; Espargaro, Alba; Sabate, Raimon; Jozwiak, Krzysztof; Wanner, Klaus T.; Salat, Kinga; Malawska, Barbara; Kulig, Katarzyna; Bajda, Marek Share Save
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Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation Malek, Rim; Simakov, Alexey; Davis, Audrey; Maj, Maciej; Bernard, Paul J.; Wnorowski, Artur; Martin, Helene; Marco-Contelles, Jose; Chabchoub, Fakher; Dallemagne, Patrick; Rochais, Christophe; Jozwiak, Krzysztof; Ismaili, Lhassane Share Save
Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist Wnorowski, Artur; Dudzik, Danuta; Bernier, Michel; Wojcik, Jakub; Keijzers, Guido; Diaz-Ruiz, Alberto; Mazur, Karolina; Zhang, Yongqing; Han, Haiyong; Scheibye-Knudsen, Morten; Jozwiak, Krzysztof; Barbas, Coral; Wainer, Irving W. Share Save
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Type I and type II positive allosteric modulators of α7 nicotinic acetylcholine receptors induce antidepressant-like activity in mice by a mechanism involving receptor potentiation but not neurotransmitter reuptake inhibition. Correlation with mTOR intracellular pathway activation Targowska-Duda, Katarzyna M.; Budzynska, Barbara; Michalak, Agnieszka; Wnorowski, Artur; Loland, Claus J.; Maj, Maciej; Manetti, Dina; Romanelli, Maria Novella; Jozwiak, Krzysztof; Biala, Grazyna; Arias, Hugo R. Share Save
Development of tricyclic N-benzyl-4-hydroxybutanamide derivatives as inhibitors of GABA transporters mGAT1-4 with anticonvulsant, antinociceptive, and antidepressant activity Zareba, Paula; Salat, Kinga; Hoefner, Georg C.; Latka, Kamil; Bajda, Marek; Latacz, Gniewomir; Kotniewicz, Krzysztof; Rapacz, Anna; Podkowa, Adrian; Maj, Maciej; Jozwiak, Krzysztof; Filipek, Barbara; Wanner, Klaus T.; Malawska, Barbara; Kulig, Katarzyna Share Save
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