Not logged in A TAK1 cytokine toxicity checkpoint controls anti-cancer immunity Djajawi, Tirta M.; Huber, Anne; Rivera, Sarahi Mendoza; Srivaths, Akash; Salehi, Maede; Gunay, Gokhan; Gerak, Chloe; Neil, Liam; Ozaydin, Oliver; Voulgaris, Olivia; Al Halawani, Aleen; Gannon, Daire; Khoshdoozmasouleh, Nooshin; Jenkins, Laura J.; Chan, Kok Fei; Behren, Andreas; Ernst, Matthias; Mielke, Lisa A.; Lelliott, Emily J.; Dong, Hao; Feltham, Rebecca; Sutton, Vivien R.; Trapani, Joseph A.; Mariadason, John M.; Pal, Bhupinder; Martin, Seamus J.; Vervoort, Stephin J.; Kearney, Conor J. Share Save
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RNA kinetics influence the response to transcriptional perturbation in leukaemia cell lines Todorovski, Izabela; Tsang, Mary-Jane; Feran, Breon; Fan, Zheng; Gadipally, Sreeja; Yoannidis, David; Kong, Isabella Y.; Bjelosevic, Stefan; Rivera, Sarahi; Voulgaris, Olivia; Zethoven, Magnus; Hawkins, Edwin D.; Simpson, Kaylene J.; Arnau, Gisela Mir; Papenfuss, Anthony T.; Johnstone, Ricky W.; Vervoort, Stephin J. Share Save
Intracellular zinc protects tumours from T cell-mediated cytotoxicity Lelliott, Emily J.; Naddaf, Jonathan; Ganio, Katherine; Michie, Jessica; Wang, Shelly; Liu, Lin; Silke, Natasha; Ahn, Antonio; Ramsbottom, Kelly M.; Brennan, Amelia J.; Freeman, Andrew J.; Goel, Shom; Vervoort, Stephin J.; Kearney, Conor J.; Beavis, Paul A.; Mcdevitt, Christopher A.; Silke, John; Oliaro, Jane Share Save
Mapping the IMiD-dependent cereblon interactome using BioID-proximity labelling Costacurta, Matteo; Sandow, Jarrod J.; Maher, Belinda; Susanto, Olivia; Vervoort, Stephin J.; Devlin, Jennifer R.; Garama, Daniel; Condina, Mark R.; Steele, Joel R.; Kahrood, Hossein V.; Gough, Daniel; Johnstone, Ricky W.; Shortt, Jake Share Save
PRMT1 acts as a suppressor of MHC-I and anti-tumor immunity Djajawi, Tirta M.; Pijpers, Lizzy; Srivaths, Akash; Chisanga, David; Chan, Kok Fei; Hogg, Simon J.; Neil, Liam; Rivera, Sarahi Mendoza; Bartonicek, Nenad; Ellis, Sarah L.; Sian, Terry C. C. Lim Kam; Faridi, Pouya; Liao, Yang; Pal, Bhupinder; Behren, Andreas; Shi, Wei; Vervoort, Stephin J.; Johnstone, Ricky W.; Kearney, Conor J. Share Save
CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity (vol 42, 113014, 2023) House, Imran G.; Derrick, Emily B.; Sek, Kevin; Chen, Amanda X. Y.; Li, Jasmine; Lai, Junyun; Todd, Kirsten L.; Munoz, Isabelle; Michie, Jessica; Chan, Cheok Weng; Huang, Yu-Kuan; Chan, Jack D.; Petley, Emma V.; Tong, Junming; Nguyen, Datminh; Engel, Sven; Savas, Peter; Hogg, Simon J.; Vervoort, Stephin J.; Kearney, Conor J.; Burr, Marian L.; Lam, Enid Y. N.; Gilan, Omer; Bedoui, Sammy; Johnstone, Ricky W.; Dawson, Mark A.; Loi, Sherene; Darcy, Phillip K.; Beavis, Paul A. Share Save
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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity House, Imran G.; Derrick, Emily B.; Sek, Kevin; Chen, Amanda X. Y.; Li, Jasmine; Lai, Junyun; Todd, Kirsten L.; Munoz, Isabelle; Michie, Jessica; Chan, Cheok Weng; Huang, Yu-Kuan; Chan, Jack D.; Petley, Emma, V; Tong, Junming; Nguyen, DatMinh; Engel, Sven; Savas, Peter; Hogg, Simon J.; Vervoort, Stephin J.; Kearney, Conor J.; Burr, Marian L.; Lam, Enid Y. N.; Gilan, Omer; Bedoui, Sammy; Johnstone, Ricky W.; Dawson, Mark A.; Loi, Sherene; Darcy, Phillip K.; Beavis, Paul A. Share Save
Distinct modulation of IFNγ-induced transcription by BET bromodomain and catalytic P300/CBP inhibition in breast cancer Hogg, Simon J.; Motorna, Olga; Kearney, Conor J.; Derrick, Emily B.; House, Imran G.; Todorovski, Izabela; Kelly, Madison J.; Zethoven, Magnus; Bromberg, Kenneth D.; Lai, Albert; Beavis, Paul A.; Shortt, Jake; Johnstone, Ricky W.; Vervoort, Stephin J. Share Save
Epigenetic modulators of B cell fate identified through coupled phenotype-transcriptome analysis Kong, Isabella Y.; Trezise, Stephanie; Light, Amanda; Todorovski, Izabela; Arnau, Gisela Mir; Gadipally, Sreeja; Yoannidis, David; Simpson, Kaylene J.; Dong, Xueyi; Whitehead, Lachlan; Tempany, Jessica C.; Farchione, Anthony J.; Sheikh, Amania A.; Groom, Joanna R.; Rogers, Kelly L.; Herold, Marco J.; Bryant, Vanessa L.; Ritchie, Matthew E.; Willis, Simon N.; Johnstone, Ricky W.; Hodgkin, Philip D.; Nutt, Stephen L.; Vervoort, Stephin J.; Hawkins, Edwin D. Share Save
Inhibition of pyrimidine biosynthesis targets protein translation in acute myeloid leukemia So, Joan; Lewis, Alexander C.; Smith, Lorey K.; Stanley, Kym; Franich, Rheana; Yoannidis, David; Pijpers, Lizzy; Dominguez, Pilar; Hogg, Simon J.; Vervoort, Stephin J.; Brown, Fiona C.; Johnstone, Ricky W.; McDonald, Gabrielle; Ulanet, Danielle B.; Murtie, Josh; Gruber, Emily; Kats, Lev M. Share Save
Integrated clinical and genomic evaluation of guadecitabine (SGI-110) in peripheral T-cell lymphoma Wong, Jonathan; Gruber, Emily; Maher, Belinda; Waltham, Mark; Sabouri-Thompson, Zahra; Jong, Ian; Luong, Quinton; Levy, Sidney; Kumar, Beena; Brasacchio, Daniella; Jia, Wendy; So, Joan; Skinner, Hugh; Lewis, Alexander; Hogg, Simon J.; Vervoort, Stephin; DiCorleto, Carmen; Uhe, Micheleine; Gamgee, Jeanette; Opat, Stephen; Gregory, Gareth P.; Polekhina, Galina; Reynolds, John; Hawkes, Eliza A.; Kailainathan, Gajan; Gasiorowski, Robin; Kats, Lev M.; Shortt, Jake Share Save
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Loss of erythroblasts in acute myeloid leukemia causes iron redistribution with clinical implications Lopes, Marta; Duarte, Tiago L.; Teles, Maria J.; Mosteo, Laura; Chacim, Sergio; Aguiar, Eliana; Pereira-Reis, Joana; Oliveira, Monica; Silva, Andre M. N.; Goncalves, Nuno; Martins, Gabriela; Kong, Isabella Y.; Zethoven, Magnus; Vervoort, Stephin; Martins, Sandra; Quintela, Miguel; Hawkins, Edwin D.; Trigo, Fernanda; Guimaraes, Joao T.; Mariz, Jose M.; Porto, Graca; Duarte, Delfim Share Save
CDK4/6 Inhibition Promotes Antitumor Immunity through the Induction of T-cell Memory Lelliott, Emily J.; Kong, Isabella Y.; Zethoven, Magnus; Ramsbottom, Kelly M.; Martelotto, Luciano G.; Meyran, Deborah; Zhu, Joe Jiang; Costacurta, Matteo; Kirby, Laura; Sandow, Jarrod J.; Lim, Lydia; Dominguez, Pilar M.; Todorovski, Izabela; Haynes, Nicole M.; Beavis, Paul A.; Neeson, Paul J.; Hawkins, Edwin D.; McArthur, Grant A.; Parish, Ian A.; Johnstone, Ricky W.; Oliaro, Jane; Sheppard, Karen E.; Kearney, Conor J.; Vervoort, Stephin J. Share Save
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