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SaveShare Save Share Save The Z isomer of pyridoxilidenerhodanine 5′-phosphate is an efficient inhibitor of human pyridoxine 5′-phosphate oxidase, a crucial enzyme in vitamin B6 salvage pathway and a potential chemotherapeutic target
Graziani, Claudio; Barile, Anna; Antonelli, Lorenzo; Fiorillo, Annarita; Ilari, Andrea; Vetica, Fabrizio; di Salvo, Martino Luigi; Paiardini, Alessandro; Tramonti, Angela; Contestabile, Roberto Share Save Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for LeishmaniasisExertier, Cecile; Salerno, Alessandra; Antonelli, Lorenzo; Fiorillo, Annarita; Ocello, Riccardo; Seghetti, Francesca; Caciolla, Jessica; Uliassi, Elisa; Masetti, Matteo; Fiorentino, Eleonora; Orsini, Stefania; Di Muccio, Trentina; Ilari, Andrea; Bolognesi, Maria Laura Share Save Share Save Sorcin promotes migration in cancer and regulates the EGF-dependent EGFR signaling pathwaysTito, Claudia; Genovese, Ilaria; Giamogante, Flavia; Benedetti, Anna; Miglietta, Selenia; Barazzuol, Lucia; Cristiano, Loredana; Iaiza, Alessia; Carolini, Sabatino; De Angelis, Luciana; Masciarelli, Silvia; Nottola, Stefania Annarita; Familiari, Giuseppe; Petrozza, Vincenzo; Lauriola, Mattia; Tamagnone, Luca; Ilari, Andrea; Cali, Tito; Valdivia, Hector H.; Valdivia, Carmen R.; Colotti, Gianni; Fazi, Francesco Share Save Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding SiteMadia, Valentina Noemi; Ialongo, Davide; Patacchini, Elisa; Exertier, Cecile; Antonelli, Lorenzo; Colotti, Gianni; Messore, Antonella; Tudino, Valeria; Saccoliti, Francesco; Scipione, Luigi; Ilari, Andrea; Costi, Roberta; Di Santo, Roberto Share Save Share Save Optimization of Potent and Specific Trypanothione Reductase Inhibitors: A Structure-Based Drug Discovery ApproachBattista, Theo; Federico, Stefano; Brogi, Simone; Pozzetti, Luca; Khan, Tuhina; Butini, Stefania; Ramunno, Anna; Fiorentino, Eleonora; Orsini, Stefania; Di Muccio, Trentina; Fiorillo, Annarita; Exertier, Cecile; Di Risola, Daniel; Ilari, Andrea; Campiani, Giuseppe; Colotti, Gianni; Gemma, Sandra Share Save Share Save Share Save Target highlights in CASP14: Analysis of models by structure providersAlexander, Leila T.; Lepore, Rosalba; Kryshtafovych, Andriy; Adamopoulos, Athanassios; Alahuhta, Markus; Arvin, Ann M.; Bomble, Yannick J.; Bottcher, Bettina; Breyton, Cecile; Chiarini, Valerio; Chinnam, Naga Babu; Chiu, Wah; Fidelis, Krzysztof; Grinter, Rhys; Gupta, Gagan D.; Hartmann, Marcus D.; Hayes, Christopher S.; Heidebrecht, Tatjana; Ilari, Andrea; Joachimiak, Andrzej; Kim, Youngchang; Linares, Romain; Lovering, Andrew L.; Lunin, Vladimir V.; Lupas, Andrei N.; Makbul, Cihan; Michalska, Karolina; Moult, John; Mukherjee, Prasun K.; Nutt, William Sam; Oliver, Stefan L.; Perrakis, Anastassis; Stols, Lucy; Tainer, John A.; Topf, Maya; Tsutakawa, Susan E.; Valdivia-Delgado, Mauricio; Schwede, Torsten Share Save DECIPHERING THE NEUROPROTECTIVE ROLE OF SIGMA1 RECEPTOR, AN IMPORTANT FUNCTION TO OVERCOME THE SYMPTOMS OF NEURODEGENERATIVE DISORDERSPascarella, Gianmarco; Battista, Theo; Colotti, Gianni; Rosati, Jessica; Fiorillo, Annarita; Narzi, Daniele; Guidoni, Leonardo; Squitieri, Ferdinando; Morea, Veronica; Ilari, Andrea Share Save Share Save Share Save Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseasesGenovese, Ilaria; Giamogante, Flavia; Barazzuol, Lucia; Battista, Theo; Fiorillo, Annarita; Vicario, Mattia; D'Alessandro, Giuseppina; Cipriani, Raffaela; Limatola, Cristina; Rossi, Daniela; Sorrentino, Vincenzo; Poser, Elena; Mosca, Luciana; Squitieri, Ferdinando; Perluigi, Marzia; Arena, Andrea; van Petegem, Filip; Tito, Claudia; Fazi, Francesco; Giorgi, Carlotta; Cali, Tito; Ilari, Andrea; Colotti, Gianni Share Save Spiro-containing derivatives show antiparasitic activity against Trypanosoma brucei through inhibition of the trypanothione reductase enzymeTurcano, Lorenzo; Battista, Theo; De Haro, Esther Torrente; Missineo, Antonino; Alli, Cristina; Paonessa, Giacomo; Colotti, Gianni; Harper, Steven; Fiorillo, Annarita; Ilari, Andrea; Bresciani, Alberto Share Save Share Save Share Save 
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