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N

N. Yan

University of California System

10H-index
58Paper Count
327Citation Count
Published Papers 9
Publication Date
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Lysine carbamoylation during urea denaturation remodels the energy landscape of human transthyretin dissociation linked to unfolding
errPROTEIN SCIENCE
IF5.2
err2025-03-25
err0
PREAI
errJager, Marcus; Mortenson, David E.; Ardejani, Maziar S.; Kline, Gabriel M.; Dendle, Maria T.; Yan, Nicholas L.; Powers, Evan T.; Gruebele, Martin
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The conformational landscape of human transthyretin revealed by cryo-EM
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2025-01-22
err1
errOAAI
errBasanta, Benjamin; Nugroho, Karina; Yan, Nicholas L.; Kline, Gabriel M.; Powers, Evan T.; Tsai, Felix J.; Wu, Mengyu; Chen, Jason S.; Forli, Stefano; Kelly, Jeffrey W.
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Discovery of Potent and Selective Pyridone-Based Small Molecule Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-12-03
err0
PREAI
errLederberg, Oren L.; Yan, Nicholas L.; Sanchez, Julian; Ren, Wen; Ash, Carl; Wilkens, Steven J.; Qiu, Huang; Qin, Bo; Grant, Virginia H.; Jackman, Alex B.; Stanfield, Robyn L.; Wilson, Ian A.; Petrassi, H. Michael; Rhoades, Derek; Kelly, Jeffery W.
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Cryo-EM structure of a novel α-synuclein filament subtype from multiple system atrophy
errFEBS LETTERS
IF3
err2024-11-07
err1
errOAAI
errYan, Nicholas L.; Candido, Francisco; Tse, Eric; Melo, Arthur A.; Prusiner, Stanley B.; Mordes, Daniel A.; Southworth, Daniel R.; Paras, Nick A.; Merz, Gregory E.
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Pharmacological stabilization of the native state of full-length immunoglobulin light chains to treat light chain amyloidosis
errCURRENT OPINION IN CHEMICAL BIOLOGY
IF6.1
err2023-08-01
err6
errOAAI
errYan, Nicholas L.; Morgan, Gareth J.; Petrassi, H. Michael; Wilson, Ian A.; Kelly, Jeffery W.
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errSave
Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-05-03
err24
errOAAI
errYan, Nicholas L.; Santos-Martins, Diogo; Nair, Reji; Chu, Alan; Wilson, Ian A.; Johnson, Kristen A.; Forli, Stefano; Morgan, Gareth J.; Petrassi, H. Michael; Kelly, Jeffery W.
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The Role of Protein Thermodynamics and Primary Structure in Fibrillogenesis of Variable Domains from Immunoglobulin Light Chains
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2019-07-31
err22
errOAAI
errRennella, Enrico; Morgan, Gareth J.; Yan, Nicholas; Kelly, Jeffery W.; Kay, Lewis E.
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Stabilization of amyloidogenic immunoglobulin light chains by small molecules
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2019-04-10
err61
errOAAI
errMorgan, Gareth J.; Yan, Nicholas L.; Mortenson, David E.; Rennella, Enrico; Blundon, Joshua M.; Gwin, Ryan M.; Lin, Chung-Yon; Stanfield, Robyn L.; Brown, Steven J.; Rosen, Hugh; Spicer, Timothy P.; Fernandez-Vega, Virneliz; Merlini, Giampaolo; Kay, Lewis E.; Wilson, Ian A.; Kelly, Jeffery W.
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errSave
Dual interaction of scaffold protein Tim44 of mitochondrial import motor with channel-forming translocase subunit Tim23
errELIFE
IF0
err2017-04-25
err37
errOAAI
errTing, See-Yeun; Yan, Nicholas L.; Schilke, Brenda A.; Craig, Elizabeth A.
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Research Directions

No research directions
Co-authors
Cooperation Journals
I
Ian A. Wilson
H-index: 179 · Papers: 1.7K
S
Stanley B. Prusiner
H-index: 155 · Papers: 653
G
Giampaolo Merlini
H-index: 121 · Papers: 1.1K
J
Jeffery W. Kelly
H-index: 119 · Papers: 611
L
Lewis E. Kay
H-index: 107 · Papers: 437
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