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Identification of a Selective Pharmacologic IRE1/XBP1s Activator with Enhanced Tissue Exposure Sun, Jie; Lee, Kyunga; Kutseikin, Sergei; Guerrero, Adrian; Rius, Bibiana; Madhavan, Aparajita; Buasakdi, Chavin; Cheong, Ka-Neng; Chatterjee, Priyadarshini; Rosen, Dorian A.; Yoon, Leonard; Ardejani, Maziar S.; Mendoza, Alejandra; Rosarda, Jessica D.; Saez, Enrique; Kelly, Jeffery W.; Wiseman, R. Luke Share Save
Proteostasis and lysosomal repair deficits in transdifferentiated neurons of Alzheimer's disease Chou, Ching-Chieh; Vest, Ryan; Prado, Miguel A.; Wilson-Grady, Joshua; Paulo, Joao A.; Shibuya, Yohei; Moran-Losada, Patricia; Lee, Ting-Ting; Luo, Jian; Gygi, Steven P.; Kelly, Jeffery W.; Finley, Daniel; Wernig, Marius; Wyss-Coray, Tony; Frydman, Judith Share Save
Activation of XBP1s attenuates disease severity in models of proteotoxic Charcot-Marie-Tooth type 1B Touvier, Thierry; Veneri, Francesca A.; Claessens, Anke; Ferri, Cinzia; Mastrangelo, Rosa; Sorgiati, Noemie; Bianchi, Francesca; Valenzano, Serena; Del Carro, Ubaldo; Rivellini, Cristina; Duong, Phu; Shy, Michael E.; Kelly, Jeffery W.; Svaren, John; Wiseman, R. Luke; D'Antonio, Maurizio Share Save
AA147 Alleviates Symptoms in a Mouse Model of Multiple Sclerosis by Reducing Oligodendrocyte Loss Aksu, Metin; Kaschke, Kevin; Podojil, Joseph R.; Chiang, Mingyi; Steckler, Ian; Bruce, Kody; Cogswell, Andrew C.; Schulz, Gwen; Kelly, Jeffery W.; Wiseman, R. Luke; Miller, Stephen D.; Popko, Brian; Chen, Yanan Share Save
Discovery of Potent and Selective Pyridone-Based Small Molecule Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Lederberg, Oren L.; Yan, Nicholas L.; Sanchez, Julian; Ren, Wen; Ash, Carl; Wilkens, Steven J.; Qiu, Huang; Qin, Bo; Grant, Virginia H.; Jackman, Alex B.; Stanfield, Robyn L.; Wilson, Ian A.; Petrassi, H. Michael; Rhoades, Derek; Kelly, Jeffery W. Share Save
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Integrative proteomics identifies a conserved Aβ amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer's disease Levites, Yona; Dammer, Eric B.; Ran, Yong; Tsering, Wangchen; Duong, Duc; Abreha, Measho; Gadhavi, Joshna; Lolo, Kiara; Trejo-Lopez, Jorge; Phillips, Jennifer; Iturbe, Andrea; Erquizi, Aya; Moore, Brenda D.; Ryu, Danny; Natu, Aditya; Dillon, Kristy; Torrellas, Jose; Moran, Corey; Ladd, Thomas; Afroz, Farhana; Islam, Tariful; Jagirdar, Jaishree; Funk, Cory C.; Robinson, Max; Rangaraju, Srikant; Borchelt, David R.; Ertekin-Taner, Nilufer; Kelly, Jeffrey W.; Heppner, Frank L.; Johnson, Erik C. B.; McFarland, Karen; Levey, Allan I.; Prokop, Stefan; Seyfried, Nicholas T.; Golde, Todd E. Share Save
Advancing Transthyretin Amyloidosis Drug Development in an Evolving Treatment Landscape: Amyloidosis Forum Meeting Proceedings Maurer, Mathew S.; Soman, Prem; Hernandez, Adrian; Garcia-Pavia, Pablo; Signorovitch, James; Wei, L. J.; Hanna, Mazen; Ruberg, Frederick L.; Kittleson, Michelle; Kazi, Dhruv; Dorbala, Sharmila; Hsu, Kristen; Lousada, Isabelle; Adigun, Rosalyn; Dunnmon, Preston; Kelly, Jeffery; Gillmore, Julian Share Save
Cutaneous biomarkers of therapeutic efficacy in early treatment of hereditary ATTR amyloid polyneuropathy with tafamidis Cardenas-Soto, Karla; Dominguez, Xel-Ha; Cortes, Giovanni; Tsai, Felix; Saniger, Maria del Mar; Guraieb-Chahin, Paola; Torres-Ocatvo, Benjamin; Gibbons, Christopher; Kelly, Jeffery W.; Freeman, Roy; Gonzalez-Duarte, Alejandra Share Save
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Divergent Proteome Reactivity Influences Arm-Selective Activation of the Unfolded Protein Response by Pharmacological Endoplasmic Reticulum Proteostasis Regulators Kline, Gabriel M.; Paxman, Ryan J.; Lin, Chung-Yon; Madrazo, Nicole; Yoon, Leonard; Grandjean, Julia M. D.; Lee, Kyunga; Nugroho, Karina; Powers, Evan T.; Wiseman, R. Luke; Kelly, Jeffery W. Share Save
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