Not logged in Development and validation of AI/ML derived splice-switching oligonucleotides Fronk, Alyssa D.; Manzanares, Miguel A.; Zheng, Paulina; Geier, Adam; Anderson, Kendall; Stanton, Shaleigh; Zumrut, Hasan; Gera, Sakshi; Munch, Robin; Frederick, Vanessa; Dhingra, Priyanka; Arun, Gayatri; Akerman, Martin Share Save
Novel splicing-derived neoantigen in triple negative breast cancer uncovered by SpliceIO™ a robust platform for the discovery and validation of disease-specific immunotherapies Williams, Nicole; Manzanares, Miguel A.; Anderson, Kendall; Zunrut, Hasan; Gera, Sakshi; Habib, Nayab; Stanton, Shaleigh; Floyd, Taylor; Shah, Sanjana; Trahan, Devon; Akerman, Martin; Arun, Gayatri Share Save
Novel immune-therapeutic target for lung cancer uncovered by SpliceIO™, an innovative platform that identifies disease-specific alternative splicing Manzanares, Miguel A.; Anderson, Kendall; Zumrut, Hasan; Gera, Sakshi; Habib, Nayab; Williams, Nicole; Stanton, Shaleigh; Floyd, Taylor; Shah, Sanjana; Trahan, Devon; Akerman, Martin; Arun, Gayatri Share Save
Computational discovery and experimental validation of splicing-derived neoantigens Zumrut, Hasan Ekrem; Anderson, Kendall; Manzanares, Miguel; Smith, Shaleigh; Gera, Sakshi; Habib, Nayab; Shah, Sanjana; Trahan, Devon; Akerman, Martin; Arun, Gayatri Share Save
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Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics Bhatia, Sonam; Kramer, Melissa; Russo, Suzanne; Naik, Payal; Arun, Gayatri; Brophy, Kyle; Andrews, Peter; Fan, Cheng; Perou, Charles M.; Preall, Jonathan; Ha, Taehoon; Plenker, Dennis; Tuveson, David A.; Rishi, Arvind; Wilkinson, John E.; McCombie, W. Richard; Kostroff, Karen; Spector, David L. Share Save
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Comprehensive analysis of structural variants in breast cancer genomes using single-molecule sequencing Aganezov, Sergey; Goodwin, Sara; Sherman, Rachel M.; Sedlazeck, Fritz J.; Arun, Gayatri; Bhatia, Sonam; Lee, Isac; Kirsche, Melanie; Wappel, Robert; Kramer, Melissa; Kostroff, Karen; Spector, David L.; Timp, Winston; McCombie, W. Richard; Schatz, Michael C. Share Save
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Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1 Abulwerdi, Fardokht A.; Xu, Wenbo; Ageeli, Abeer A.; Yonkunas, Michael J.; Arun, Gayatri; Nam, Hyeyeon; Schneekloth, John S., Jr.; Dayie, Theodore Kwaku; Spector, David; Baird, Nathan; Le Grice, Stuart F. J. Share Save
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Differentiation of mammary tumors and reduction in metastasis upon Malat1 LncRNA loss Arun, Gayatri; Diermeier, Sarah; Akerman, Martin; Chang, Kung-Chi; Wilkinson, J. Erby; Hearn, Stephen; Kim, Youngsoo; MacLeod, A. Robert; Krainer, Adrian R.; Norton, Larry; Brogi, Edi; Egeblad, Mikala; Spector, David L. Share Save
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The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells Gutschner, Tony; Haemmerle, Monika; Eissmann, Moritz; Hsu, Jeff; Kim, Youngsoo; Hung, Gene; Revenko, Alexey; Arun, Gayatri; Stentrup, Marion; Gross, Matthias; Zoernig, Martin; MacLeod, A. Robert; Spector, David L.; Diederichs, Sven Share Save
The lncRNA Malat1 Is Dispensable for Mouse Development but Its Transcription Plays a cis-Regulatory Role in the Adult Zhang, Bin; Arun, Gayatri; Mao, Yuntao S.; Lazar, Zsolt; Hung, Gene; Bhattacharjee, Gourab; Xiao, Xiaokun; Booth, Carmen J.; Wu, Jie; Zhang, Chaolin; Spector, David L. Share Save