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M

Mary‐Ellen Harper

university of ottawa

79H-index
341Paper Count
2.5WCitation Count
Published Papers 139
Publication Date
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Skeletal muscle reprogramming of metabolic, ribosomal and developmental pathways contributes to Roux-en-Y gastric bypass-induced adaptation in women
errEBioMedicine
IF10.8
err2026-07-31
err0
errOAAI
errChantal A. Pileggi; Dhanuddara Mohottalage; Luke S. Kennedy; Majid Nikpay; Lauren M.K. Hamilton; Martín Roffe; Michel N. Kanaan; Amer Jarrar; Nicole Kolozsvari; Dongdong Wang; Miroslava Cuperlovic-Culf; Tommy Alain; Gregory R. Steinberg; Ruth McPherson; Robert Dent; Mary-Ellen Harper
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Functional and metabolomic analyses of brown adipose tissue during cold-deacclimation reveal rapid N-acetylated amino acid metabolism adaptations
erriScience
IF4.1
err2026-02-25
err0
errOAAI
errChantal A. Pileggi; Ella McIlroy; Lauren M.K. Hamilton; Nidhi Kuksal; Luke S. Kennedy; Valeria Vasilyeva; Michel Kanaan; Ziyad El Hankouri; Yan Burelle; Miroslava Cuperlovic-Culf; Mary-Ellen Harper
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Integrated bioinformatic and in vivo analysis confirms the cardioprotective role of OPA1
errBMC CARDIOVASCULAR DISORDERS
IF2.3
err2025-12-09
err0
PREAI
errFong-McMaster, Claire; Pulente, Serena M.; Kennedy, Luke S.; Smith, Tyler K. T.; Myers, Stephanie; Kanaan, Michel N.; Karam, Charbel Y.; Cope, Matthew; Levesque, Michelle M.; Mcilroy, Ella; Lorenzen-Schmidt, Ilka; Goergen, Craig J.; Fullerton, Morgan D.; Cuperlovic-Culf, Miroslava; Mulvihill, Erin E.; Harper, Mary-Ellen
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errSave
Intestinal adaptation to cold-induced metabolic demand and feeding requires GLP-1R and GLP-2R signalling
errCommunications Biology
IF5.1
err2025-12-04
err0
errOAAI
errNadya M. Morrow; Antonio A. Hanson; Claire Fong-McMaster; Dawson B. H. Livingston; Hoda Osman; Lauren Hamilton; Natasha A. Trzaskalski; Cassandra A. A. Locatelli; Mélodie N. Bellefleur; Ethel Messika-Zeitoun; Sebastian M. Cino; Serena M. Pulente; Iryna Abramchuk; Xiaoling Zhao; Ilka Lorenzen-Schmidt; Arianne Morissette; Krista A. Power; Mary-Ellen Harper; Erin E. Mulvihill
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errSave
Computational approaches to enzymatic reaction assignment: a review of methods, validations, and future directions
errBRIEFINGS IN BIOINFORMATICS
IF7.7
err2025-11-01
err0
PREAI
errKennedy, Luke; Harper, Mary-Ellen; Cuperlovic-Culf, Miroslava
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errSave
Succinate-driven cardiac mitochondrial respiration aligns with whole-animal hypoxia-tolerance in African mole-rats
errMAMMALIAN BIOLOGY
IF0
err2025-09-01
err0
PREAI
errMunro, Daniel; Hart, Daniel W.; Bennett, Nigel C.; Van Jaarvsveld, Barry; Devereaux, Maiah E. M.; Campbell, Kevin L.; Sebaa, Rajaa; Van Dermeeren, Emmanuel; Harper, Mary-Ellen; Blier, Pierre U.; Pamenter, Matthew E.
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errSave
Impaired xCT-mediated cystine uptake drives serine and proline metabolic reprogramming and mitochondrial fission in skeletal muscle cells
errRedox Biology
IF11.9
err2025-08-21
err0
errOAAI
errMichel N. Kanaan; Charbel Y. Karam; Luke S. Kennedy; Chantal A. Pileggi; Lauren Hamilton; Miroslava Cuperlovic-Culf; Mary-Ellen Harper
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errSave
A hybrid machine learning framework for functional annotation of mitochondrial glutathione transport and metabolism proteins in cancers
errBMC BIOINFORMATICS
IF3.3
err2025-02-11
err0
errOAAI
errKennedy, Luke; Sandhu, Jagdeep K.; Harper, Mary-Ellen; Cuperlovic-Culf, Miroslava
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errSave
AMPK-mediated regulation of endogenous cholesterol synthesis does not affect atherosclerosis in a murine Pcsk9-AAV model
errATHEROSCLEROSIS
IF5.7
err2024-10-01
err0
PREAI
errSmith, Tyler K. T.; Ghorbani, Peyman; Leblond, Nicholas D.; Nunes, Julia R. C.; O'Dwyer, Conor; Ambursley, Nia; Fong-McMaster, Claire; Minarrieta, Lucia; Burkovsky, Leah A.; El-Hakim, Rama; Trzaskalski, Natasha A.; Locatelli, Cassandra A. A.; Stotts, Cameron; Pember, Ciara; Rayner, Katey J.; Kemp, Bruce E.; Loh, Kim; Harper, Mary-Ellen; Mulvihill, Erin E.; St-Pierre, Julie; Fullerton, Morgan D.
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errSave
Cystine/glutamate antiporter xCT controls skeletal muscle glutathione redox, bioenergetics and differentiation
errREDOX BIOLOGY
IF11.9
err2024-07-01
err2
errOAAI
errKanaan, Michel N.; Pileggi, Chantal A.; Karam, Charbel Y.; Kennedy, Luke S.; Fong-McMaster, Claire; Cuperlovic-Culf, Miroslava; Harper, Mary-Ellen
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PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2024-06-13
err1
PREAI
errHodgins, Jonathan J.; Abou-Hamad, John; O'Dwyer, Colin Edward; Hagerman, Ash; Yakubovich, Edward; Tanese de Souza, Christiano; Marotel, Marie; Buchler, Ariel; Fadel, Saleh; Park, Maria M.; Fong-McMaster, Claire; Crupi, Mathieu F.; Makinson, Olivia Joan; Kurdieh, Reem; Rezaei, Reza; Dhillon, Harkirat Singh; Ilkow, Carolina S.; Bell, John C.; Harper, Mary-Ellen; Rotstein, Benjamin H.; Auer, Rebecca C.; Vanderhyden, Barbara C.; Sabourin, Luc A.; Bourgeois-Daigneault, Marie-Claude; Cook, David P.; Ardolino, Michele
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The integrated stress response promotes neural stem cell survival under conditions of mitochondrial dysfunction in neurodegeneration
errAGING CELL
IF7.1
err2024-05-16
err3
errOAAI
errIqbal, Mohamed Ariff; Bilen, Maria; Liu, Yubing; Jabre, Vanessa; Fong, Bensun C.; Chakroun, Imane; Paul, Smitha; Chen, Jingwei; Wade, Steven; Kanaan, Michel; Harper, Mary-Ellen; Khacho, Mireille; Slack, Ruth S.
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errSave
Accessory subunit NDUFB4 participates in mitochondrial complex I supercomplex formation
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-02-01
err4
errOAAI
errParmar, Gaganvir; Fong-McMaster, Claire; Pileggi, Chantal A.; Patten, David A.; Cuillerier, Alexanne; Myers, Stephanie; Wang, Ying; Hekimi, Siegfried; Cuperlovic-Culf, Miroslava; Harper, Mary-Ellen
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errSave
ATF2 orchestrates macrophage differentiation and activation to promote antibacterial responses
errJOURNAL OF LEUKOCYTE BIOLOGY
IF3.1
err2023-07-04
err3
errOAAI
errRajabalee, Nusrah; Siushansian, Hannah; Weerapura, Milani; Berton, Stefania; Berbatovci, Fjolla; Hooks, Breana; Geoffrion, Michele; Yang, Dabo; Harper, Mary-Ellen; Rayner, Katey; Blais, Alexandre; Sun, Jim
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16p11.2 haploinsufficiency reduces mitochondrial biogenesis in brain endothelial cells and alters brain metabolism in adult mice
errCELL REPORTS
IF6.9
err2023-05-01
err4
errOAAI
errBeland-Millar, Alexandria; Kirby, Alexia; Truong, Yen; Ouellette, Julie; Yandiev, Sozerko; Bouyakdan, Khalil; Pileggi, Chantal; Naz, Shama; Yin, Melissa; Carrier, Micael; Kotchetkov, Pavel; St-Pierre, Marie-Kim; Tremblay, Marie-Eve; Courchet, Julien; Harper, Mary-Ellen; Alquier, Thierry; Messier, Claude; Shuhendler, Adam J.; Lacoste, Baptiste
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errSave
Novel Homozygous Variant in COQ7 in Siblings With Hereditary Motor Neuropathy
errNEUROLOGY-GENETICS
IF3.7
err2023-02-01
err7
errOAAI
errSmith, Ian C.; Pileggi, Chantal A.; Wang, Ying; Kernohan, Kristin; Hartley, Taila; McMillan, Hugh J.; Sampaio, Marcos Loreto; Melkus, Gerd; Woulfe, John; Parmar, Gaganvir; Bourque, Pierre R.; Breiner, Ari; Zwicker, Jocelyn; Pringle, C. Elizabeth; Jarinova, Olga; Lochmueller, Hanns; Dyment, David A.; Brais, Bernard; Boycott, Kym M.; Hekimi, Siegfried; Harper, Mary-Ellen; Warman-Chardon, Jodi
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errSave
Parkin coregulates glutathione metabolism in adult mammalian brain
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2023-01-23
err6
errOAAI
errEl Kodsi, Daniel N. N.; Tokarew, Jacqueline M. M.; Sengupta, Rajib; Lengacher, Nathalie A. A.; Chatterji, Ajanta; Nguyen, Angela P. P.; Boston, Heather; Jiang, Qiubo; Palmberg, Carina; Pileggi, Chantal; Holterman, Chet E. E.; Shutinoski, Bojan; Li, Juan; Fehr, Travis K.; LaVoie, Matthew J.; Ratan, Rajiv R. R.; Shaw, Gary S. S.; Takanashi, Masashi; Hattori, Nobutaka; Kennedy, Christopher R. R.; Harper, Mary-Ellen; Holmgren, Arne; Tomlinson, Julianna J. J.; Schlossmacher, Michael G. G.
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errSave
Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesity
errEBIOMEDICINE
IF10.8
err2022-09-01
err14
errOAAI
errPileggi, Chantal A.; Blondin, Denis P.; Hooks, Breana G.; Parmar, Gaganvir; Alecu, Irina; Patten, David A.; Cuillerier, Alexanne; O'Dwyer, Conor; Thrush, A. Brianne; Fullerton, Morgan D.; AL Bennett, Steffany; Doucet, Eric; Haman, Francois; Cuperlovic-Culf, Miroslava; McPherson, Ruth; Dent, Robert R. M.; Harper, Mary-Ellen
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errSave
Targeting skeletal muscle mitochondrial health in obesity
errCLINICAL SCIENCE
IF7.7
err2022-07-27
err6
errOAAI
errPileggi, Chantal A.; Hooks, Breana G.; McPherson, Ruth; Dent, Robert R. M.; Harper, Mary-Ellen
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errSave
Prohibitin 1 interacts with p53 in the regulation of mitochondrial dynamics and chemoresistance in gynecologic cancers
errJOURNAL OF OVARIAN RESEARCH
IF4.2
err2022-06-07
err6
errOAAI
errKong, Bao; Han, Chae Young; Kim, Se Ik; Patten, David A.; Han, Youngjin; Carmona, Euridice; Shieh, Dar-Bin; Cheung, Annie C.; Mes-Masson, Anne-Marie; Harper, Mary-Ellen; Song, Yong Sang; Tsang, Benjamin K.
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Research Directions

No research directions
Co-authors
Cooperation Journals
B
Bruce M. Spiegelman
H-index: 186 · Papers: 471
T
Tak W. Mak
H-index: 181 · Papers: 1.6K
N
Nahum Sonenberg
H-index: 178 · Papers: 957
M
Markku Laakso
H-index: 171 · Papers: 1.2K
G
George A. Wells
H-index: 164 · Papers: 1.3K
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