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SaveHypertrophic cardiomyopathy-associated mutations drive stromal activation via EGFR-mediated paracrine signaling
Ewoldt, Jourdan K.; Wang, Miranda C.; McLellan, Micheal A.; Cloonan, Paige E.; Chopra, Anant; Gorham, Joshua; Li, Linqing; DeLaughter, Daniel M.; Gao, Xining; Lee, Joshua H.; Willcox, Jon A. L.; Layton, Olivia; Luu, Rebeccah J.; Toepfer, Christopher N.; Eyckmans, Jeroen; Seidman, Christine E.; Seidman, Jonathan G.; Chen, Christopher S. Share Save Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organizationZhang, Kehan; Cloonan, Paige E.; Sundaram, Subramanian; Liu, Feng; Das, Shoshana L.; Ewoldt, Jourdan K.; Bays, Jennifer L.; Tomp, Samuel; Toepfer, Christopher N.; Marsiglia, Julia D. C.; Gorham, Joshua; Reichart, Daniel; Eyckmans, Jeroen; Seidman, Jonathan G.; Seidman, Christine E.; Chen, Christopher S. Share Save Share Save Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in TNNI3 and TNNT2 That Are Common in Chinese PatientsPua, Chee Jian; Tham, Nevin; Chin, Calvin W. L.; Walsh, Roddy; Khor, Chiea Chuen; Toepfer, Christopher N.; Repetti, Giuliana G.; Garfinkel, Amanda C.; Ewoldt, Jourdan F.; Cloonan, Paige; Chen, Christopher S.; Lim, Shi Qi; Cai, Jiashen; Loo, Li Yang; Kong, Siew Ching; Chiang, Charleston W. K.; Whiffin, Nicola; de Marvao, Antonio; Lio, Pei Min; Hii, An An; Yang, Cheng Xi; Le, Thu Thao; Bylstra, Yasmin; Lim, Weng Khong; Teo, Jing Xian; Padilha, Kallyandra; Silva, Gabriela V.; Pan, Bangfen; Govind, Risha; Buchan, Rachel J.; Barton, Paul J. R.; Tan, Patrick; Foo, Roger; Yip, James W. L.; Wong, Raymond C. C.; Chan, Wan Xian; Pereira, Alexandre C.; Tang, Hak Chiaw; Jamuar, Saumya Shekhar; Ware, James S.; Seidman, Jonathan G.; Seidman, Christine E.; Cook, Stuart A. Share Save Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic CardiomyopathyToepfer, Christopher N.; Garfinkel, Amanda C.; Venturini, Gabriela; Wakimoto, Hiroko; Repetti, Giuliana; Alamo, Lorenzo; Sharma, Arun; Agarwal, Radhika; Ewoldt, Jourdan F.; Cloonan, Paige; Letendre, Justin; Lun, Mingyue; Olivotto, Iacopo; Colan, Steve; Ashley, Euan; Jacoby, Daniel; Michels, Michelle; Redwood, Charles S.; Watkins, Hugh C.; Day, Sharlene M.; Staples, James F.; Padron, Raul; Chopra, Anant; Ho, Carolyn Y.; Chen, Christopher S.; Pereira, Alexandre C.; Seidman, Jonathan G.; Seidman, Christine E. Share Save Share Save Share Save Share Save Share Save 
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