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Chester A. Mathis

university of pittsburgh

116H-index
728Paper Count
5.9WCitation Count
Published Papers 177
Publication Date
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Autoradiography and preclinical PET studies with radiolabeled asyn-44 and ACI-12589 for imaging α-synuclein
errJournal of Parkinsons Disease
IF5
err2026-04-17
err0
PREAI
errCassis Varlow; Anna Pees; Jeffrey S Stehouwer; Ann-Kathrin Grotegerd; Daniel Bleher; Dinahlee Saturnino Guarino; Anton Lindberg; Junchao Tong; Brian J Lopresti; Ashley C Knight; Merlin Zabrocki; Arafat Nasser; Vladimir Shalgunov; Elena Ferri; Giuseppe Cannazza; Paul McQuade; Chester A Mathis; Robert H Mach; Umberto M Battisti; Kristina Herfert; Matthias M Herth; Gitte M Knudsen; Neil Vasdev
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Structure-based optimization and binding assays for discovery of tau PET radiotracers: synthesis and in vivo evaluation of [11C]Z-3272
errCANADIAN JOURNAL OF CHEMISTRY
IF1
err2025-10-01
err0
PREAI
errd'Orchymont, Faustine; Tong, Junchao; Kaplan, Anat Levit; Shoichet, Brian; Mathis, Chester A.; Stehouwer, Jeffrey S.; Vasdev, Neil
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First-in-human PET neuroimaging of [18F]OXD-2314
errEuropean Journal of Nuclear Medicine and Molecular Imaging
IF7.6
err2025-06-24
err0
errOAAI
errEmily Murrell; Lucas Narciso; Kimberly L. Desmond; Caitlin Chow; Anton Lindberg; Armando Garcia; Chester A. Mathis; Samuel Svensson; Antonio P. Strafella; Neil Vasdev
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An inverse association of cerebral amyloid-β deposition and serum docosahexaenoic acid levels in cognitively normal older adults in Japan
errJOURNAL OF ALZHEIMERS DISEASE
IF3.1
err2025-05-08
err0
PREAI
errSekikawa, Akira; Higashiyama, Aya; Lopresti, Brian J.; Ihara, Masafumi; Cui, Chendi; Li, Jiatong; Watanabe, Makoto; Li, Mengyi; Goon, Shatabdi; Aizenstein, Howard J.; Chang, Yuefang; Kakuta, Chikage; Yu, Zheming; Mathis, Chester A.; Kokubo, Yoshihiro; Royse, Sarah; Fukuda, Tetsuya; Snitz, Beth; Lopez, Oscar L.; Miyamoto, Yoshihiro
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Structure-Activity Relationships and Evaluation of 2-(Heteroaryl-cycloalkyl)-1H-indoles as Tauopathy Positron Emission Tomography Radiotracers
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-03-11
err0
errOAAI
errStehouwer, Jeffrey S.; Huang, Guofeng; Guarino, Dinahlee Saturnino; Debnath, Manik L.; Polu, Ashok; Geib, Steven J.; Lopresti, Brian; Ikonomovic, Milos D.; Mason, Neale; Mach, Robert H.; Mathis, Chester A.
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Radiosynthesis, In Vitro Characterization, and In Vivo PET Neuroimaging of [18F]F-4 for Tau Protein: A First-in-Human PET Study
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2025-03-10
err0
errOAAI
errLindberg, A; Tong, JC; Zheng, C; Mueller, A; Kroth, H; Stephens, A; Mathis, CA; Vasdev, N
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errSave
The development of a PET radiotracer for imaging alpha synuclein aggregates in Parkinson's disease
errRSC MEDICINAL CHEMISTRY
IF3.6
err2025-01-01
err0
PREAI
errTian, Gui-Long; Hsieh, Chia-Ju; Guarino, Dinahlee Saturnino; Graham, Thomas J. A.; Lengyel-Zhand, Zsofia; Schmitz, Alexander; Chia, Wai Kit; Young, Anthony J.; Crosby, John-Grey; Plakas, Konstantinos; Huang, Tianyu; Jiang, Hao; Yu, Yanbo; Hou, Catherine; Lee, Hsiaoju; Petersson, E. James; Giannakoulias, Sam; O'Shea, Jennifer; Kotzbauer, Paul; Tu, Zhude; Mathis, Chester A.; Mach, Robert H.
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errSave
Ligand-based design of [18F]OXD-2314 for PET imaging in non-Alzheimer's disease tauopathies
errNATURE COMMUNICATIONS
IF15.7
err2024-06-14
err1
errOAAI
errLindberg, Anton; Murrell, Emily; Tong, Junchao; Mason, N. Scott; Sohn, Daniel; Sandell, Johan; Strom, Peter; Stehouwer, Jeffrey S.; Lopresti, Brian J.; Viklund, Jenny; Svensson, Samuel; Mathis, Chester A.; Vasdev, Neil
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errSave
Kinetic modeling of the monoamine oxidase-B radioligand [18F]SMBT-1 in human brain with positron emission tomography
errJOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
IF4.5
err2024-05-12
err0
PREAI
errLopresti, Brian J.; Stehouwer, Jeffrey; Reese, Alexandria C.; Mason, Neale S.; Royse, Sarah K.; Narendran, Rajesh; Laymon, Charles M.; Lopez, Oscar L.; Cohen, Ann D.; Mathis, Chester A.; Villemagne, Victor L.
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errSave
Development of Pyridothiophene Compounds for PET Imaging of α-Synuclein
errCHEMISTRY-A EUROPEAN JOURNAL
IF3.7
err2024-03-08
err2
errOAAI
errPees, Anna; Tong, Junchao; Birudaraju, Saritha; Munot, Yogeshkumar S.; Liang, Steven H.; Guarino, Dinahlee Saturnino; Mach, Robert H.; Mathis, Chester A.; Vasdev, Neil
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In vitro evaluation of [3H]PI-2620 and structural derivatives in non-Alzheimer's tauopathies
errNUCLEAR MEDICINE AND BIOLOGY
IF3
err2024-03-01
err6
errOAAI
errVarlow, Cassis; Mathis, Chester A.; Vasdev, Neil
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errSave
Association Between β-Amyloid Accumulation and Incident Dementia in Individuals 80 Years or Older Without Dementia
errNEUROLOGY
IF8.5
err2024-01-23
err0
PREAI
errLopez, Oscar L.; Villemagne, Victor L.; Chang, Yue-Fang; Cohen, Ann D.; Klunk, William E.; Mathis, Chester A.; Pascoal, Tharick; Ikonomovic, Milos D.; Rowe, Christopher; Dore, Vincent; Snitz, Beth E.; Lopresti, Brian J.; Kamboh, M. Ilyas; Aizenstein, Howard J.; Kuller, Lewis H.
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Biostatistical Estimation of Tau Threshold Hallmarks (BETTH) Algorithm for Human Tau PET Imaging Studies
errJOURNAL OF NUCLEAR MEDICINE
IF9.1
err2023-09-14
err4
errOAAI
errGogola, Alexandra; Lopresti, Brian J.; Tudorascu, Dana; Snitz, Beth; Minhas, Davneet; Dore, Vincent; Ikonomovic, Milos D.; Shaaban, C. Elizabeth; Matan, Cristy; Bourgeat, Pierrick; Mason, N. Scott; Aizenstein, Howard; Mathis, Chester A.; Klunk, William E.; Rowe, Christopher C.; Lopez, Oscar L.; Cohen, Ann D.; Villemagne, Victor L.
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Low thalamic activity during a digit-symbol substitution task is associated with symptoms of subjective cognitive decline
errFRONTIERS IN PSYCHIATRY
IF3.2
err2023-09-06
err0
errOAAI
errMizuno, Akiko; Karim, Helmet Talib; Ly, Maria J.; Lopresti, Brian J.; Cohen, Ann D.; Ali, Areej A.; Mathis, Chester A.; Klunk, William E.; Aizenstein, Howard J.; Snitz, Beth E.
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errSave
A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-08-31
err5
PREAI
errKim, Ho Young; Chia, Wai Kit; Hsieh, Chia-Ju; Saturnino Guarino, Dinahlee; Graham, Thomas J. A.; Lengyel-Zhand, Zsofia; Schneider, Mark; Tomita, Cosette; Lougee, Marshall G.; Kim, Hee Jong; Pagar, Vinayak V.; Lee, Hsiaoju; Hou, Catherine; Garcia, Benjamin A.; Petersson, E. James; O'Shea, Jennifer; Kotzbauer, Paul T.; Mathis, Chester A.; Lee, Virginia M. -Y.; Luk, Kelvin C.; Mach, Robert H.
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errSave
Characterizing the emergence of amyloid and tau burden in Down syndrome
errALZHEIMERS & DEMENTIA
IF11.1
err2023-08-29
err9
errOAAI
errZammit, Matthew D.; Betthauser, Tobey J.; Mcvea, Andrew K.; Laymon, Charles M.; Tudorascu, Dana L.; Johnson, Sterling C.; Hartley, Sigan L.; Converse, Alexander K.; Minhas, Davneet S.; Zaman, Shahid H.; Ances, Beau M.; Stone, Charles K.; Mathis, Chester A.; Cohen, Annie D.; Klunk, William E.; Handen, Benjamin L.; Christian, Bradley T.
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In Silico Discovery and Subsequent Characterization of Potent 4R-Tauopathy Positron Emission Tomography Radiotracers
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-07-24
err8
errOAAI
errGraham, Thomas J. A.; Lindberg, Anton; Tong, Junchao; Stehouwer, Jeffrey S.; Vasdev, Neil; Mach, Robert H.; Mathis, Chester A.
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errSave
Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search
errMOLECULAR IMAGING AND BIOLOGY
IF2.5
err2023-03-29
err5
errOAAI
errJanssen, Bieneke; Tian, Guilong; Lengyel-Zhand, Zsofia; Hsieh, Chia-Ju; Lougee, Marshall G.; Riad, Aladdin; Xu, Kuiying; Hou, Catherine; Weng, Chi-Chang; Lopresti, Brian J.; Kim, Hee Jong; Pagar, Vinayak V.; Ferrie, John J.; Garcia, Benjamin A.; Mathis, Chester A.; Luk, Kelvin; Petersson, E. James; Mach, Robert H.
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Prefrontal and Striatal Dopamine Release Are Inversely Correlated in Schizophrenia
errBIOLOGICAL PSYCHIATRY
IF9
err2022-11-01
err24
errOAAI
errFrankle, W. Gordon; Himes, Michael; Mathis, Chester A.; Narendran, Rajesh
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errSave
Low untreated systolic blood pressure over 18 years is associated with survival free of dementia age 90+
errALZHEIMERS & DEMENTIA
IF11.1
err2022-01-28
err0
errOAAI
errKuller, Lewis H.; Snitz, Beth E.; Hughes, Timothy M.; Chang, Yuefang; Cohen, Anne D.; Mathis, Chester A.; Aizenstein, Howard J.; Lopez, Oscar L.
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Research Directions

No research directions
Co-authors
Cooperation Journals
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John Q. Trojanowski
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Luigi Ferrucci
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Paul M. Thompson
H-index: 222 · Papers: 4.3K
J
John C. Morris
H-index: 212 · Papers: 2.4K
R
Ronald C. Petersen
H-index: 205 · Papers: 2.0K
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