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Shinya Ito

university of toronto

60H-index
515Paper Count
1.3WCitation Count
Published Papers 138
Publication Date
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A unified physiologically based pharmacokinetic model for low-to-high oral, subcutaneous, and intravenous dose of methotrexate in humans
errJournal of Pharmaceutical Sciences
IF3.8
err2026-06-02
err0
errOAAI
errMin-Soo Kim; Shirley Wang; Paola Mian; Yves Theoret; Julie Autmizguine; Shinya Ito; Andrea N. Edginton
errShare
errSave
The “Route Cause” of Methotrexate-Induced Brain Structure Changes in a Juvenile Mouse Model: Comparison of Systemic and CNS-Targeted Chemotherapy
errNeuroToxicology
IF3.9
err2025-12-11
err0
PREAI
errSun Eui Choi; Tiffany Ayoub; Gail Lee; Anne L. Wheeler; Sharon L. Guger; Rosanna Weksberg; Shinya Ito; Russell J. Schachar; Johann Hitzler; Brian J. Nieman
errShare
errSave
DNA methylation alterations in acute lymphoblastic leukemia survivors with late neurocognitive deficits
errLeukemia
IF13.4
err2025-10-17
err0
errOAAI
errSarah J. Goodman; Darci T. Butcher; Sharon L. Guger; Eric Diehl; Jack Brzezinski; Brenda Spiegler; Brian J. Nieman; Prajkta Kallurkar; Aubrée Boulet Craig; Maja Krajinovic; Julie Laniel; Caroline Laverdière; Daniel Sinnett; Sarah Lippé; Andrei Turinsky; Mary Shago; Lisa J. Strug; Shinya Ito; Johann K. Hitzler; Russell Schachar; Rosanna Weksberg
errShare
errSave
Il-6 knockout reduces doxorubicin-induced toxicity in the developing mouse brain
errbrain behavior and immunity
IF0
err2025-06-28
err0
PREAI
errJonas Yeung; Henry Quach; Amy P. Wong; Anne L. Wheeler; Rosanna Weksberg; Sharon L. Guger; Russell J. Schachar; Shinya Ito; Johann Hitzler; Brian J. Nieman
errShare
errSave
Impaired Drug Metabolism Caused by Compound Heterozygous Loss-of-Function Variants in CYP3A4: A Case Report
errClinical Pharmacology & Therapeutics
IF5.5
err2025-04-28
err0
PREAI
errHan Byul Kang; Iris Cohn; Sanjay Mahant; Gregory Costain; Shinya Ito; Ruud H.J. Verstegen
errShare
errSave
Reduction of tumor necrosis factor (TNF) in milk of women receiving anti-TNF antibody
errPEDIATRIC RESEARCH
IF3.1
err2024-11-01
err1
PREAI
errSepiashvili, Lusia; Brydon, Avery; Koroshegyi, Christine; Gold, Anna; Dalvi, Pooja; Ghayoori, Sholeh; Rahman, Mehzabin; Huang, Vivian; Maxwell, Cynthia; Nguyen, Geoffrey C.; Ito, Shinya
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errSave
Targeting AGAT gene expression - a drug screening approach for the treatment of GAMT deficiency
errEXPERT OPINION ON DRUG DISCOVERY
IF4.9
err2024-10-15
err1
errOAAI
errTkachyova, Ilona; Tropak, Michael B.; Lee, Alex; Datti, Alessandro; Ito, Shinya; Schulze, Andreas
errShare
errSave
Vitamin K Antagonists for Pregnant Women With Antiphospholipid Antibodies: A Scoping Review
errJOURNAL OF RHEUMATOLOGY
IF3.4
err2024-08-01
err0
PREAI
errZarek, Judith; Lee, Jinyoung; Harakati, Deema; Spitzer, Karen; Laskin, Carl A.; Ito, Shinya
errShare
errSave
HSP47 levels determine the degree of body adiposity
errNATURE COMMUNICATIONS
IF15.7
err2023-11-11
err3
errOAAI
errShin, Jihoon; Toyoda, Shinichiro; Okuno, Yosuke; Hayashi, Reiko; Nishitani, Shigeki; Onodera, Toshiharu; Sakamoto, Haruyo; Ito, Shinya; Kobayashi, Sachiko; Nagao, Hirofumi; Kita, Shunbun; Otsuki, Michio; Fukuhara, Atsunori; Nagata, Kazuhiro; Shimomura, Iichiro
errShare
errSave
Safety of medicines during breastfeeding - from case report to modeling: a contribution from the ConcePTION project
errEXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY
IF3.4
err2023-06-13
err3
PREAI
errCardoso, Evelina; Guidi, Monia; Nauwelaerts, Nina; Nordeng, Hedvig; Teil, Marie; Allegaert, Karel; Smits, Anne; Gandia, Peggy; Edginton, Andrea; Ito, Shinya; Annaert, Pieter; Panchaud, Alice
errShare
errSave
Microwaves reduce water refractive index
errSCIENTIFIC REPORTS
IF3.9
err2022-07-07
err4
errOAAI
errAsakuma, Yusuke; Maeda, Tomoisa; Takai, Takahiro; Hyde, Anita; Phan, Chi; Ito, Shinya; Taue, Shuji
errShare
errSave
On-demand drug quantification: an increasing need in pediatric patients
errPEDIATRIC RESEARCH
IF3.1
err2022-05-06
err0
PREAI
errVerstegen, Ruud H. J.; Jung, Benjamin; Lewis, Tamorah R.; Ito, Shinya
errShare
errSave
A pharmacogenomic investigation of the cardiac safety profile of ondansetron in children and pregnant women
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2022-04-01
err1
errOAAI
errDrogemoller, Britt, I; Wright, Galen E. B.; Trueman, Jessica; Shaw, Kaitlyn; Staub, Michelle; Chaudhry, Shahnaz; Miao, Fudan; Higginson, Michelle; Groeneweg, Gabriella S. S.; Brown, James; Magee, Laura A.; Whyte, Simon D.; West, Nicholas; Brodie, Sonia M.; 't Jong, Geert; Israels, Sara; Berger, Howard; Ito, Shinya; Rassekh, Shahrad R.; Sanatani, Shubhayan; Ross, Colin J. D.; Carleton, Bruce C.
errShare
errSave
Population pharmacokinetics of vancomycin in paediatric patients with febrile neutropenia and augmented renal clearance: development of new dosing recommendations
errJOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
IF3.6
err2021-09-04
err13
PREAI
errShimamoto, Yuko; Verstegen, Ruud H. J.; Mizuno, Tomoyuki; Schechter, Tal; Allen, Upton; Ito, Shinya
errShare
errSave
Incorporating Breastfeeding-Related Variability with Physiologically Based Pharmacokinetic Modeling to Predict Infant Exposure to Maternal Medication Through Breast Milk: a Workflow Applied to Lamotrigine (vol 23, 70, 2021)
errAAPS JOURNAL
IF3.7
err2021-07-13
err0
errOAAI
errYeung, Cindy H. T.; Ito, Shinya; Autmizguine, Julie; Edginton, Andrea N.
errShare
errSave
Quality Control of Procollagen in Cells
errANNUAL REVIEW OF BIOCHEMISTRY, VOL 90, 2021
IF0
err2021-06-20
err21
errOAAI
errIto, Shinya; Nagata, Kazuhiro
errShare
errSave
Incorporating Breastfeeding-Related Variability with Physiologically Based Pharmacokinetic Modeling to Predict Infant Exposure to Maternal Medication Through Breast Milk: a Workflow Applied to Lamotrigine (vol 23, 70, 2021)
errAAPS JOURNAL
IF3.7
err2021-06-10
err0
errOAAI
errYeung, Cindy H. T.; Ito, Shinya; Autmizguine, Julie; Edginton, Andrea N.
errShare
errSave
Assessment of the Implementation of Pharmacogenomic Testing in a Pediatric Tertiary Care Setting
errJAMA NETWORK OPEN
IF9.7
err2021-05-26
err19
errOAAI
errCohn, Iris; Manshaei, Roozbeh; Liston, Eriskay; Okello, John B. A.; Khan, Reem; Curtis, Meredith R.; Krupski, Abby J.; Jobling, Rebekah K.; Kalbfleisch, Kelsey; Paton, Tara A.; Reuter, Miriam S.; Hayeems, Robin Z.; Verstegen, Ruud H. J.; Goldman, Aaron; Kim, Raymond H.; Ito, Shinya
errShare
errSave
Incorporating Breastfeeding-Related Variability with Physiologically Based Pharmacokinetic Modeling to Predict Infant Exposure to Maternal Medication Through Breast Milk: a Workflow Applied to Lamotrigine
errAAPS JOURNAL
IF3.7
err2021-05-17
err11
errOAAI
errYeung, Cindy H. T.; Ito, Shinya; Autmizguine, Julie; Edginton, Andrea N.
errShare
errSave
Cognitive and behavioral risk factors for low quality of life in survivors of childhood acute lymphoblastic leukemia
errPEDIATRIC RESEARCH
IF3.1
err2020-11-17
err13
errOAAI
errvan der Plas, Ellen; Spencer Noakes, T. Leigh; Butcher, Darci T.; Weksberg, Rosanna; Galin-Corini, Laura; Wanstall, Elizabeth A.; Te, Patrick; Hopf, Laura; Guger, Sharon; Hitzler, Johann; Schachar, Russell J.; Ito, Shinya; Nieman, Brian J.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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