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Hetero-oligomerization of TDP-43 carboxy-terminal fragments with cellular proteins contributes to proteotoxicity Kitamura, Akira; Fujimoto, Ai; Kawashima, Rei; Lyu, Yidan; Sasaki, Kotetsu; Hamada, Yuta; Moriya, Kanami; Kurata, Ayumi; Takahashi, Kazuho; Brielmann, Renee; Bott, Laura C.; Morimoto, Richard I.; Kinjo, Masataka Share Save
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Aging is associated with a systemic length-associated transcriptome imbalance Stoeger, Thomas; Grant, Rogan A.; McQuattie-Pimentel, Alexandra C.; Anekalla, Kishore R.; Liu, Sophia S.; Tejedor-Navarro, Heliodoro; Singer, Benjamin D.; Abdala-Valencia, Hiam; Schwake, Michael; Tetreault, Marie-Pier; Perlman, Harris; Balch, William E.; Chandel, Navdeep S.; Ridge, Karen M.; Sznajder, Jacob, I; Morimoto, Richard, I; Misharin, Alexander, V; Budinger, G. R. Scott; Amaral, Luis A. Nunes Share Save
Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons Capano, Lucia S.; Sato, Chihiro; Ficulle, Elena; Yu, Anan; Horie, Kanta; Kwon, Ji-Sun; Burbach, Kyle F.; Barthelemy, Nicolas R.; Fox, Susan G.; Karch, Celeste M.; Bateman, Randall J.; Houlden, Henry; Morimoto, Richard, I; Holtzman, David M.; Duff, Karen E.; Yoo, Andrew S. Share Save
Autophagy in healthy aging and disease Aman, Yahyah; Schmauck-Medina, Tomas; Hansen, Malene; Morimoto, Richard, I; Simon, Anna Katharina; Bjedov, Ivana; Palikaras, Konstantinos; Simonsen, Anne; Johansen, Terje; Tavernarakis, Nektarios; Rubinsztein, David C.; Partridge, Linda; Kroemer, Guido; Labbadia, John; Fang, Evandro F. Share Save
ERdj8 governs the size of autophagosomes during the formation process (vol 219, e201903127, 2020) Yamamoto, Yo-Hei; Kasai, Ayano; Omori, Hiroko; Takino, Tomoe; Sugihara, Munechika; Umemoto, Tetsuo; Hamasaki, Maho; Hatta, Tomohisa; Natsume, Tohru; Morimoto, Richard I.; Arai, Ritsuko; Waguri, Satoshi; Sato, Ken; Bar-Nun, Shoshana; Yoshimori, Tamotsu; Noda, Takeshi; Nagata, Kazuhiro Share Save
The 2021 FASEB Virtual Catalyst Conference on Extracellular and Organismal Proteostasis in Health and Disease, February 3-4, 2021 Lior, Chen; Hodge, Francesca; De-Souza, Evandro A.; Bourboulia, Dimitra; Calderwood, Stuart K.; David, Della; Allan Drummond, D.; Edkins, Adrienne; Morimoto, Richard I.; Prahlad, Veena; Rechavi, Oded; Sistonen, Lea; Wilson, Mark; Wiseman, R. Luke; Zanetti, Maurizio; Taylor, Rebecca; Scherz-Shouval, Ruth; van Oosten-Hawle, Patricija Share Save
Resetting proteostasis with ISRIB promotes epithelial differentiation to attenuate pulmonary fibrosis Watanabe, Satoshi; Markov, Nikolay S.; Lu, Ziyan; Aillon, Raul Piseaux; Soberanes, Saul; Runyan, Constance E.; Ren, Ziyou; Grant, Rogan A.; Maciel, Mariana; Abdala-Valencia, Hiam; Politanska, Yuliya; Nam, Kiwon; Sichizya, Lango; Kihshen, Hermon G.; Joshi, Nikita; McQuattie-Pimentel, Alexandra C.; Gruner, Katherine A.; Jain, Manu; Sznajder, Jacob I.; Morimoto, Richard I.; Reyfman, Paul A.; Gottardi, Cara J.; Budinger, G. R. Scott; Misharin, Alexander V. Share Save
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The lung microenvironment shapes a dysfunctiona response of alveolar macrophages in aging McQuattie-Pimentel, Alexandra C.; Ren, Ziyou; Joshi, Nikita; Watanabe, Satoshi; Stoeger, Thomas; Chi, Monica; Lu, Ziyan; Sichizya, Lango; Aillon, Raul Piseaux; Chen, Ching-, I; Soberanes, Saul; Chen, Zhangying; Reyfman, Paul A.; Walter, James M.; Anekalla, Kishore R.; Davis, Jennifer M.; Helmin, Kathryn A.; Runyan, Constance E.; Abdala-Valencia, Hiam; Nam, Kiwon; Meliton, Angelo Y.; Winter, Deborah R.; Morimoto, Richard, I; Mutlu, Gokhan M.; Bharat, Ankit; Perlman, Harris; Gottardi, Cara J.; Ridge, Karen M.; Chandel, Navdeep S.; Sznajder, Jacob, I; Balch, William E.; Singer, Benjamin D.; Misharin, Alexander, V; Budinger, G. R. Scott Share Save
ERdj8 governs the size of autophagosomes during the formation process (vol 219, e201903127, 2020) Yamamoto, Yo-hei; Kasai, Ayano; Omori, Hiroko; Takino, Tomoe; Sugihara, Munechika; Umemoto, Tetsuo; Hamasaki, Maho; Hatta, Tomohisa; Natsume, Tohru; Morimoto, Richard I.; Arai, Ritsuko; Waguri, Satoshi; Sato, Miyuki; Sato, Ken; Bar-Nun, Shoshana; Yoshimori, Tamotsu; Noda, Takeshi; Nagata, Kazuhiro Share Save
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