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C. Roland Wolf

University of Dundee

90H-index
721Paper Count
3.2WCitation Count
Published Papers 178
Publication Date
Correction: The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals
err2026-06-27
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errOAAI
errC. J. Henderson; A. W. McLaren; A. K. MacLeod; D. Lin; A. R. Cameron; L. R. Chatham; J. Moggs; F. Inesta‑Vaquera; John P. Thomson; Richard R. Meehan; P. Chakravarty; M. Schwarz; C. Roland Wolf
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Humanization of Drug Metabolism in the Plasmodium berghei Mouse Model for Antimalarial Drug Discovery
err2025-11-30
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errOAAI
errA. Kenneth MacLeod; Cristina Merino; Sara Viera-Morilla; Laura Frame; Amy Tavendale; Christina Duncan; Liam Ferguson; Erika G. Pinto; Frederick R. C. Simeons; Vanessa Gomez-Jimenez; Ana Belén García; Jennifer Riley; Yoko Shishikura; María Santos Martínez- Martínez; C. Roland Wolf; Kevin D. Read
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Integration of in vivo stress reporters with transcription profiling to define chemical mixtures mechanisms of toxicity, including trans-generational effects.
err2025-09-08
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PREAI
errFrancisco Inesta-Vaquera; Wenduo Qi; Silviya Dimova-Vasileva; G. Jean Campbell; Febe Ferro; Richard Meehan; Sari Pennings; C. Roland Wolf
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APPLICATION OF A MOUSE MODEL HUMANIZED FOR CYTOCHROME P450-MEDIATED DRUG METABOLISM TO PREDICT DRUG-DRUG INTERACTIONS BETWEEN PEPTIDE AND SMALL MOLECULE DRUGS
err2025-08-26
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PREAI
errYury Kapelyukh; Charlotte Gabel-Jensen; Alastaire Kenneth MacLeod; Kevin-Sebastien Daniel Coquelin; Laste Stojanovski; Laura Frame; Amy Tavendale; Colin J. Henderson; Kevin D. Read; Charles Roland Wolf; Carolina Säll
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The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals
err2025-03-05
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errOAAI
errHenderson, C. J.; Mclaren, A. W.; Macleod, A. K.; Lin, D.; Cameron, A. R.; Chatham, L. R.; Moggs, J.; Inesta-Vaquera, F.; Thomson, John P.; Meehan, Richard R.; Chakravarty, P.; Schwarz, M.; Wolf, C. Roland
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Use of an extensively humanized mouse model to predict the risk of drug-drug interactions in patients receiving dexamethasone
err2025-02-01
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PREAI
errGeorge, Jacob; Chalmers, James D.; Coquelin, Kevin-Sebastien; Frame, Laura; Henderson, Colin J.; Kapelyukh, Yury; Lang, Chim C.; Read, Kevin D.; Stanley, Lesley A.; Wolf, C. Roland
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Simulating BRAFV600E-MEK-ERK signalling dynamics in response to vertical inhibition treatment strategies
err2024-05-15
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errOAAI
errDe Carli, Alice; Kapelyukh, Yury; Kursawe, Jochen; Chaplain, Mark A. J.; Wolf, C. Roland; Hamis, Sara
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Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism
err2024-02-05
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errOAAI
errMacleod, Kenneth; Coquelin, Kevin-Sebastien; Huertas, Leticia; Simeons, Frederick R. C.; Riley, Jennifer; Casado, Patricia; Guijarro, Laura; Casanueva, Ruth; Frame, Laura; Pinto, Erika G.; Ferguson, Liam; Duncan, Christina; Mutter, Nicole; Shishikura, Yoko; Henderson, Colin J.; Cebrian, David; Wolf, C. Roland; Read, Kevin D.
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Defining the in vivo mechanism of air pollutant toxicity using murine stress response biomarkers
err2023-08-01
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errOAAI
errInesta-Vaquera, Francisco; Miyashita, Lisa; Grigg, Jonathan; Henderson, Colin J.; Wolf, C. Roland
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Identification of novel roles of the cytochrome P450 system in early embryogenesis: Effects on vasculogenesis and retinoic acid homeostasis
err2023-03-27
err160
errOAAI
errOtto, DME; Henderson, CJ; Carrie, D; Davey, M; Gundersen, TE; Blomhoff, R; Adams, RH; Tickle, C; Wolf, CR
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Cholesterol Metabolism: the Main Pathway Acting Downstream of Cytochrome P450 Oxidoreductase in Skeletal Development of the Limb
err2023-03-21
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errOAAI
errSchmidt, Katy; Hughes, Catherine; Chudek, J. A.; Goodyear, Simon R.; Aspden, Richard M.; Talbot, Richard; Gundersen, Thomas E.; Blomhoff, Rune; Henderson, Colin; Wolf, C. Roland; Tickle, Cheryll
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Quantifying ERK activity in response to inhibition of the BRAFV600E-MEK-ERK cascade using mathematical modelling
err2021-10-07
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errOAAI
errHamis, Sara J.; Kapelyukh, Yury; McLaren, Aileen; Henderson, Colin J.; Wolf, C. Roland; Chaplain, Mark A. J.
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Nrf2 activation does not affect adenoma development in a mouse model of colorectal cancer
err2021-09-15
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errOAAI
errKnatko, Elena, V; Castro, Cecilia; Higgins, Maureen; Zhang, Ying; Honda, Tadashi; Henderson, Colin J.; Wolf, C. Roland; Griffin, Julian L.; Dinkova-Kostova, Albena T.
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Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity
err2021-02-01
err10
errOAAI
errInesta-Vaquera, Francisco; Navasumrit, Panida; Henderson, Colin J.; Frangova, Tanya G.; Honda, Tadashi; Dinkova-Kostova, Albena T.; Ruchirawat, Mathuros; Wolf, C. Roland
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Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion
err2019-10-15
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errOAAI
errVitobello, Antonio; Perner, Juliane; Beil, Johanna; Zhu, Jiang; Del Rio-Espinola, Alberto; Morawiec, Laurent; Westphal, Magdalena; Dubost, Valerie; Altorfer, Marc; Naumann, Ulrike; Mueller, Arne; Kapur, Karen; Borowsky, Mark; Henderson, Colin; Wolf, C. Roland; Schwarz, Michael; Moggs, Jonathan; Terranova, Remi
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Application of a mouse model humanized for the major pathways of drug disposition in anticancer drug development and use
err2019-07-01
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PREAI
errHenderson, Colin J.; Scheer, Nico; Kapelyukh, Yury; McLaren, Aileen; MacLeod, Kenneth; Rode, Anja; Lin, De; Wolf, C. Roland
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Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine
err2019-03-01
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errOAAI
errReed, Lindsay; Indra, Radek; Mrizova, Iveta; Moserova, Michaela; Schmeiser, Heinz H.; Wolf, C. Roland; Henderson, Colin J.; Stiborova, Marie; Phillips, David H.; Arlt, Volker M.
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The BRandO BiO registry - A multicenter regional registry for patients with primary breast and ovarian cancer with longitudinal biobanking and evaluation of epidemiological, life style and quality of life factors
err2019-02-15
err0
PREAI
errHuober, J.; Nagel, G.; Rempen, A.; Schlicht, E.; Flock, F.; Fritz, S.; Thiel, F.; Wiesmuller, L.; Felderbaum, R.; Heilmann, V.; Bekes, I.; Fink, V.; Albrecht, S.; De Gregorio, N.; Tzschaschel, M.; Ernst, K.; Wolf, C.; Kuhn, P.; Friedl, T.; Janni, W.; De Gregorio, A.
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