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D

Dirk Grimm

Faculty of Engineering Sciences

58H-index
252Paper Count
1.4WCitation Count
Published Papers 127
Publication Date
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Bone- and muscle-targeted adeno-associated viral vectors enable tissue-selective vitamin D receptor knockdown in mice
errGene Therapy
IF4.5
err2026-07-29
err0
errOAAI
errAlexandra K. O’Donohue; Julian Chu; Nicholas Norris; Hsien-Yin Kao; Josephine Yu; Lucinda R. Lee; Dirk Grimm; Jenny E. Gunton; Aaron Schindeler
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Distinct YY dinucleotide periodicity in Adeno-associated virus (AAV) DNA
errMolecular Therapy
IF12
err2026-07-08
err0
errOAAI
errConradin Baumgartl; Jonas Becker; Lena Naber; Man Xu; Emma Gerstmann; Julie Garcia Gonzalez-Calero; Joyce Suppacher; Sebastian Heß; Felix Bubeck; Dirk Grimm
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errSave
DKK3 Initially Preserves Acinar Integrity Through MEK-Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer
errAdvanced Science
IF14.1
err2025-10-28
err0
errOAAI
errDharini Srinivasan; Elodie Roger; Lukas Perkhofer; Eleni Zimmer; Thomas F.E. Barth; Julia P. Mosler; Anna Härle; Stephanie E. Weissinger; Nadine T. Gaisa; Peter Möller; Nico Fischer; Chantal Allgöwer; J.-Matthias Löhr; Dirk Grimm; Thomas Seufferlein; Stefan Liebau; Ninel Azoitei; Michael K. Melzer; Frank Arnold; Johann Gout; Alexander Kleger
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errSave
A myotropic AAV vector combined with skeletal muscle cis-regulatory elements improve glycogen clearance in mouse models of Pompe disease
errMOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT
IF4.7
err2025-06-01
err0
errOAAI
errP. Sellier; F. Collaud; Y. Krimi Benchekroun; V. Jimenez; X. Leon; N. Daniele; Q.H. Pham; J. El Andari; T. VandenDriessche; M.K. Chuah; D. Grimm; F. Bosch; F. Mingozzi; G. Ronzitti
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errSave
Identification of a robust promoter in mouse and human hepatocytes by in vivo biopanning of a barcoded AAV library
errMolecular Therapy
IF12
err2025-04-21
err0
PREAI
errJonas Becker; Claire Domenger; Pervinder Choksi; Chiara Krämer; Conradin Baumgartl; Olena Maiakovska; Jae-Jun Kim; Jonas Weinmann; Georg Huber; Florian Schmidt; Christian Thirion; Oliver J. Müller; Holger Willenbring; Dirk Grimm
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errSave
AAV vector engineering for human aorta transduction: becoming a smooth operator
errGENE THERAPY
IF4.5
err2025-03-17
err0
PREAI
errRapti, Kleopatra; Grimm, Dirk
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errSave
Directed Evolution of AAV9 for Efficient Gene Expression in Cardiomyocytes In Vitro and In Vivo
errgene therapy
IF4
err2025-02-01
err0
PREAI
errHuettermann, Leonard; Schroeder, Lena C.; Shetty, Prithviraj M. V.; Jonker, Timo; Hille, Susanne S.; Remes, Anca Kliesow; Matzen, Andrea; Boender, Arie R.; Grimm, Dirk; Frank, Derk; Boink, Gerard J. J.; Eschenhagen, Thomas; Schade, Dennis; Mueller, Oliver J.
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errSave
T-cell specific in vivo gene delivery with DART-AAVs targeted to CD8
errMOLECULAR THERAPY
IF12
err2024-10-01
err0
errOAAI
errDemircan, Muhammed Burak; Zinser, Luca J.; Michels, Alexander; Guaza-Lasheras, Mar; John, Fabian; Gorol, Johanna M.; Theuerkauf, Samuel A.; Guenther, Dorothee M.; Grimm, Dirk; Greten, Florian R.; Chlanda, Petr; Thalheimer, Frederic B.; Buchholz, Christian J.
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errSave
Seroprevalence of binding and neutralizing antibodies against 18 adeno-associated virus types in patients with neuromuscular disorders
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-09-27
err1
errOAAI
errWang, Xiaoyan; Klann, Patrick Julian; Wiedtke, Ellen; Sano, Yumi; Fischer, Nico; Schiller, Lisa; Elfert, Anna; Guettsches, Anne-Katrin; Weyen, Ute; Grimm, Dirk; Vorgerd, Matthias; Bayer, Wibke
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errSave
An hepatitis B and D virus infection model using human pluripotent stem cell-derived hepatocytes
errEMBO REPORTS
IF6.2
err2024-09-04
err0
errOAAI
errChi, Huanting; Qu, Bingqian; Prawira, Angga; Richardt, Talisa; Maurer, Lars; Hu, Jungen; Fu, Rebecca M.; Lempp, Florian A.; Zhang, Zhenfeng; Grimm, Dirk; Wu, Xianfang; Urban, Stephan; Dao Thi, Viet Loan
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errSave
Influence of AAV vector tropism on long-term expression and Fc-γ receptor binding of an antibody targeting SARS-CoV-2
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-07-16
err0
errOAAI
errWagner, Jannik T.; Mueller-Schmucker, Sandra M.; Wang, Wenjun; Arnold, Philipp; Uhlig, Nadja; Issmail, Leila; Eberlein, Valentina; Damm, Dominik; Roshanbinfar, Kaveh; Ensser, Armin; Oltmanns, Friederike; Peter, Antonia Sophia; Temchura, Vladimir; Schroedel, Silke; Engel, Felix B.; Thirion, Christian; Grunwald, Thomas; Wuhrer, Manfred; Grimm, Dirk; Ueberla, Klaus
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errSave
Treatment of infantile-onset Pompe disease in a rat model with muscle-directed AAV gene therapy
errMOLECULAR METABOLISM
IF6.6
err2024-03-01
err3
errOAAI
errMunoz, Sergio; Bertolin, Joan; Jimenez, Veronica; Jaen, Maria Luisa; Garcia, Miquel; Pujol, Anna; Vila, Laia; Sacristan, Victor; Barbon, Elena; Ronzitti, Giuseppe; El Andari, Jihad; Tulalamba, Warut; Pham, Quang Hong; Ruberte, Jesus; VandenDriessche, Thierry; Chuah, Marinee K.; Grimm, Dirk; Mingozzi, Federico; Bosch, Fatima
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errSave
AAV vectors displaying bispecific DARPins enable dual-control targeted gene delivery
errBIOMATERIALS
IF12.9
err2023-12-01
err6
errOAAI
errTheuerkauf, Samuel A.; Herrera-Carrillo, Elena; John, Fabian; Zinser, Luca J.; Molina, Mariano A.; Riechert, Vanessa; Thalheimer, Frederic B.; Boerner, Kathleen; Grimm, Dirk; Chlanda, Petr; Berkhout, Ben; Buchholz, Christian J.
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errSave
Substrate Stiffness and Particle Properties Influence Cellular Uptake of Nanoparticles and Viruses from the Ventral Side
errADVANCED FUNCTIONAL MATERIALS
IF19
err2023-08-23
err5
errOAAI
errVoigt, Jonah L.; Timmer, Jens; Pennarola, Federica; Christian, Joel; Meng, Ning; Blumberg, Johannes W.; Schwarz, Ulrich S.; Grimm, Dirk; Cavalcanti-Adam, Elisabetta Ada
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errSave
Direct fluorescent labeling of NF186 and NaV1.6 in living primary neurons using bioorthogonal click chemistry
errJOURNAL OF CELL SCIENCE
IF3.6
err2023-06-28
err7
errOAAI
errStajkovic, Nevena; Liu, Yuanyuan; Arsic, Aleksandra; Meng, Ning; Lyu, Hang; Zhang, Nan; Grimm, Dirk; Lerche, Holger; Nikic-Spiegel, Ivana
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errSave
Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy
errNATURE COMMUNICATIONS
IF15.7
err2023-06-22
err16
errOAAI
errGrosch, Markus; Schraft, Laura; Chan, Adrian; Kuechenhoff, Leonie; Rapti, Kleopatra; Ferreira, Anne-Maud; Kornienko, Julia; Li, Shengdi; Radke, Michael H.; Kraemer, Chiara; Clauder-Muenster, Sandra; Perlas, Emerald; Backs, Johannes; Gotthardt, Michael; Dieterich, Christoph; van den Hoogenhof, Maarten M. G.; Grimm, Dirk; Steinmetz, Lars M.
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errSave
Membrane remodelling triggers maturation of excitation-contraction coupling in 3D-shaped human-induced pluripotent stem cell-derived cardiomyocytes
errBASIC RESEARCH IN CARDIOLOGY
IF8
err2023-03-29
err4
errOAAI
errKermani, Fatemeh; Mosqueira, Matias; Peters, Kyra; Lemma, Enrico D. D.; Rapti, Kleopatra; Grimm, Dirk; Bastmeyer, Martin; Laugsch, Magdalena; Hecker, Markus; Ullrich, Nina D. D.
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errSave
Boosters for adeno-associated virus (AAV) vector (r)evolution
errCYTOTHERAPY
IF3.2
err2023-03-01
err4
PREAI
errSzumska, Joanna; Grimm, Dirk
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errSave
Structural remodeling triggers functional maturation in human iPSC-derived cardiomyocytes
errJOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
IF4.7
err2022-12-01
err0
PREAI
errKermani, Fatemeh; Lemma, Enrico; Rapti, Kleopatra; Grimm, Dirk; Bastmeyer, Martin; Hecker, Markus; Ullrich, Nina
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errSave
Development of a mouse model for Sars-Cov-2 studies in the heart
errJOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
IF4.7
err2022-12-01
err0
errOAAI
errDuran, Javier; Stolp, Bettina; Becker, Jonas; Dewenter, Matthias; Pepin, Mark; Ambiel, Ina; Grimm, Dirk; Fackler, Oliver; Backs, Johannes
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Research Directions

No research directions
Co-authors
Cooperation Journals
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Ralph S. Baric
H-index: 147 · Papers: 1.1K
P
Peter Lichter
H-index: 146 · Papers: 1.0K
R
Roland Eils
H-index: 138 · Papers: 1.1K
C
Christian Trautwein
H-index: 126 · Papers: 1.7K
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