Diane M. Simeone - Publications, H-index & Citations

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Diane M. Simeone

carl gustav carus university hospital

78H-index

717Paper Count

3.1WCitation Count

Published Papers 211

Publication Date

Nectin-4 reduces T cell effector function and is a therapeutic target in pancreatic cancer

JCI Insight

IF6.1

2026-01-23

PREAI

Heiduk, Max; Beer, Carolin; Cronjaeger, Sarah; Kawaler, Emily A.; Sommer, Ulrich; Baenke, Franziska; Digomann, David; Bufe, Loreen Natusch; Reiche, Charlotte; Gluck, Jessica; Hoffmann, Franziska; Kim, Sungsik; Stange, Daniel E.; Simeone, Diane M.; Weitz, Jurgen; Seifert, Lena; Seifert, Adrian M.

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Targeting FSP1 triggers ferroptosis in lung cancer

Nature

IF48.5

2025-11-05

OAAI

Katherine Wu; Alec J. Vaughan; Jozef P. Bossowski; Yuan Hao; Aikaterini Ziogou; Seon Min Kim; Tae Ha Kim; Mari N. Nakamura; Ray Pillai; Mariana Mancini; Sahith Rajalingam; Mingqi Han; Toshitaka Nakamura; Lidong Wang; Suckwoo Chung; Diane Simeone; David Shackelford; Yun Pyo Kang; Marcus Conrad; Thales Papagiannakopoulos

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Validation of a Serum-Based Biomarker Signature for Detection of Early-Stage Pancreatic Ductal Adenocarcinoma

Gastroenterology

IF25.1

2025-10-27

OAAI

Aimee L. Lucas; Diane M. Simeone; Bryson W. Katona; Salvatore Paiella; George Zogopoulos; Rosalie C. Sears; Eli M. Grindedal; Raymond C. Wadlow; Erkut Borazanci; Ora K. Gordon; Fay Kastrinos; Jose G. Trevino; Sonia S. Kupfer; Walter G. Park; Jessica N. Everett; Natasha M. Kureshi; George DeMuth; Lisa Ford; Thomas King; Norma A. Palma; Randall E. Brand

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Recurrent BEND2 Fusion Genes Identified by Whole Transcriptome Sequencing of Non-Functional Pancreatic Neuroendocrine Tumors Correlate with Poor Patient Prognosis

Modern Pathology

IF5.5

2025-08-08

OAAI

Michelle A. Wood-Trageser; C. Tolson Nichols; Danielle A. Hutchings; Diana Bell; Abigail I. Wald; Katelyn Smith; Seung-Mo Hong; Claudio Luchini; Lodewijk A.A. Brosens; Anna Vera D. Verschuur; Michele Bevere; Rita T. Lawlor; Aldo Scarpa; Shannon Keating; James Tucker; Roderick J. O’Sullivan; Ta-Chiang Liu; Kevin McGrath; Kenneth Fasanella; Randall E. Brand; Anne Marie Lennon; Rohit Das; Harkirat Singh; Adam Slivka; Sultan Mahmood; Amy E. Hosmer; Asif Khalid; Stephanie L. Romutis; Amer H. Zureikat; Herbert J. Zeh; Melissa E. Hogg; Kenneth K. Lee; Alessandro Paniccia; Geoffrey Nunns; Melanie Ongchin; Walter G. Park; Patricio M. Polanco; Jin He; Diane M. Simeone; Cristina R. Ferrone; Dennis Hsu; Janie Zhang; Vikram Gorantla; John Rhee; Ralph H. Hruban; Anju H. Singhi; Sara A. Singhi; Candice K. Wang; Nuha Shaker; Robert Bubar; Maria Grupillo; Yi-Tak Lai; Marina N. Nikiforova; Christopher M. Heaphy; Kevin M. Waters; Aatur D. Singhi

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Identification of patients at risk for pancreatic cancer in a 3-year timeframe based on machine learning algorithms

SCIENTIFIC REPORTS

IF3.9

2025-04-05

OAAI

Zhu, Weicheng; Chen, Long; Aphinyanaphongs, Yindalon; Kastrinos, Fay; Simeone, Diane M.; Pochapin, Mark; Stender, Cody; Razavian, Narges; Gonda, Tamas A.

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Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2

CELL

IF42.5

2025-02-01

PREAI

Lucotti, Serena; Ogitani, Yusuke; Kanific, Candia M.; Geri, Jacob; Kim, Young Hun; Gu, Jinghua; Balaji, Uthra; Bojmar, Linda; Shaashua, Lee; Song, Yi; Cioffi, Michele; Lauritzen, Pernille; Joseph, Oveen M.; Asao, Tetsuhiko; Grandgenett, Paul M.; Hollingsworth, Michael A.; Peralta, Christopher; Pagano, Alexandra E.; Molina, Henrik; Lengel, Harry B.; Dunne, Elizabeth G.; Jing, Xiaohong; Schmitter, Madeleine; Borriello, Lucia; Miller, Thomas; Zhang, Haiying; Romin, Yevgeniy; Manova, Katia; Paul, Doru; Remmel, H. Lawrence; O'Reilly, Eileen M.; Janagin, William R.; Kelsen, David; Castellino, Sharon M.; Giulino-Roth, Lisa; Jones, David R.; Condeelis, John S.; Pascual, Virginia; Bussel, James B.; Boudreau, Nancy; Matei, Irina; Entenberg, David; Bromberg, Jacqueline F.; Simeone, Diane M.; Lyden, David

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A blood-based, multiplex protein biomarker signature shows superior performance in detection of early-stage pancreatic ductal adenocarcinoma (PDAC)

CANCER RESEARCH

IF16.6

2024-09-15

PREAI

Palma, Norma; Schiess, Ralph; King, Thomas; Athanasiou, Alcibiade; Kureshi, Natasha; Ford, Lisa; Lucas, Aimee; Katona, Bryson; Brand, Randall; Simeone, Diane

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Detecting HLA loss of heterozygosity within a standard diagnostic sequencing workflow for prognostic and therapeutic opportunities

NPJ PRECISION ONCOLOGY

IF8

2024-08-05

OAAI

Lozac'hmeur, Ariane; Danek, Tyler; Yang, Qidi; Rosasco, Mario G.; Welch, John S.; Go, William Y.; Ng, Eric W.; Mardiros, Armen; Maloney, David G.; Garon, Edward B.; Kirtane, Kedar; Simeone, Diane M.; Molina, Julian R.; Salahudeen, Ameen A.; Stein, Michelle M.; Hecht, J. Randolph

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Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer

NATURE MEDICINE

IF50

2024-06-28

OAAI

Bojmar, Linda; Zambirinis, Constantinos P.; Hernandez, Jonathan M.; Chakraborty, Jayasree; Shaashua, Lee; Kim, Junbum; Johnson, Kofi Ennu; Hanna, Samer; Askan, Gokce; Burman, Jonas; Ravichandran, Hiranmayi; Zheng, Jian; Jolissaint, Joshua S.; Srouji, Rami; Song, Yi; Choubey, Ankur; Kim, Han Sang; Cioffi, Michele; van Beek, Elke; Sigel, Carlie; Jessurun, Jose; Velasco Riestra, Paulina; Blomstrand, Hakon; Joensson, Carolin; Joensson, Anette; Lauritzen, Pernille; Buehring, Weston; Ararso, Yonathan; Hernandez, Dylanne; Vinagolu-Baur, Jessica P.; Friedman, Madison; Glidden, Caroline; Firmenich, Laetitia; Lieberman, Grace; Mejia, Dianna L.; Nasar, Naaz; Mutvei, Anders P.; Paul, Doru M.; Bram, Yaron; Costa-Silva, Bruno; Basturk, Olca; Boudreau, Nancy; Zhang, Haiying; Matei, Irina R.; Hoshino, Ayuko; Kelsen, David; Sagi, Irit; Scherz, Avigdor; Scherz-Shouval, Ruth; Yarden, Yosef; Oren, Moshe; Egeblad, Mikala; Lewis, Jason S.; Keshari, Kayvan; Grandgenett, Paul M.; Hollingsworth, Michael A.; Rajasekhar, Vinagolu K.; Healey, John H.; Bjoernsson, Bergthor; Simeone, Diane M.; Tuveson, David A.; Iacobuzio-Donahue, Christine A.; Bromberg, Jaqueline; Vincent, C. Theresa; O'Reilly, Eileen M.; DeMatteo, Ronald P.; Balachandran, Vinod P.; D'Angelica, Michael I.; Kingham, T. Peter; Allen, Peter J.; Simpson, Amber L.; Elemento, Olivier; Sandstroem, Per; Schwartz, Robert E.; Jarnagin, William R.; Lyden, David

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The role of family history in predicting germline pathogenic variant carriers who develop pancreatic cancer: Results of a multicenter collaboration

CANCER

IF5.1

2024-05-29

OAAI

Karloski, Eve; Dudley, Beth; Diergaarde, Brenda; Blanco, Amie; Everett, Jessica N.; Levinson, Elana; Rangarajan, Tara; Stanich, Peter P.; Childers, Kimberly; Brown, Sandra; Drogan, Christine; Cavestro, Giulia Martina; Gordon, Kelly; Singh, Aparajita; Simeone, Diane M.; Reich, Hannah; Kastrinos, Fay; Zakalik, Dana; Hampel, Heather; Pearlman, Rachel; Gordon, Ora K.; Kupfer, Sonia S.; Puzzono, Marta; Zuppardo, Raffaella Alessia; Brand, Randall E.

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The Pancreatic Cancer Early Detection (PRECEDE) Study is a Global Effort to Drive Early Detection: Baseline Imaging Findings in High-Risk Individuals

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK

IF16.4

2024-04-01

OAAI

Zogopoulos, George; Haimi, Ido; Sanoba, Shenin A.; Everett, Jessica N.; Wang, Yifan; Katona, Bryson W.; Farrell, James J.; Grossberg, Aaron J.; Paiella, Salvatore; Klute, Kelsey A.; Bi, Yan; Wallace, Michael B.; Kwon, Richard S.; Stoffel, Elena M.; Wadlow, Raymond C.; Sussman, Daniel A.; Merchant, Nipun B.; Permuth, Jennifer B.; Golan, Talia; Raitses-Gurevich, Maria; Lowy, Andrew M.; Liau, Joy; Jeter, Joanne M.; Lindberg, James M.; Chung, Daniel C.; Earl, Julie; Brentnall, Teresa A.; Schrader, Kasmintan A.; Kaul, Vivek; Huang, Chenchan; Chandarana, Hersh; Smerdon, Caroline; Graff, John J.; Kastrinos, Fay; Kupfer, Sonia S.; Lucas, Aimee L.; Sears, Rosalie C.; Brand, Randall E.; Parmigiani, Giovanni; Simeone, Diane M.

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Somatic Mutational Analysis in Endoscopic Ultrasound-Guided Biopsy of Pancreatic Adenocarcinoma: Assessing Yield and Impact

AMERICAN JOURNAL OF GASTROENTEROLOGY

IF7.6

2024-03-28

PREAI

Dong, Sue; Agarunov, Emil; Fasullo, Matthew; Kim, Ki-Yoon; Khanna, Lauren; Haber, Gregory; Janec, Eileen; Simeone, Diane; Oberstein, Paul; Gonda, Tamas

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Clonal heterogeneity in human pancreatic adenocarcinoma and its contribution to therapeutic resistance

CANCER RESEARCH

IF16.6

2024-01-16

PREAI

Kalfakakou, Despoina; Kawaler, Emily A.; Tamayo, Dylan; Wang, Lidong; Hernandez, Rosmel; Ackermann, Amanda; Jing, Xiaohong; Hajdu, Cristina; Loomis, Cynthia; Heguy, Adrianna; Lund, Amanda W.; Welling, Theodore H.; Dolgalev, Igor; Tsirigos, Aristotelis; Simeone, Diane M.

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Dual epigenetic therapy combined with anti-PD1 rescues HMA-induced suppressive myeloid phenotype and reduces tumor growth in a PDAC model

CANCER RESEARCH

IF16.6

2024-01-16

PREAI

Orlacchio, Arturo; Muzyka, Stephen; Do, Catherine; Simeone, Diane M.; Gonda, Tamas

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An organoids-on-a-chip model to recapitulate and dissect the tumor microenvironment of PDAC

CANCER RESEARCH

IF16.6

2024-01-16

PREAI

Liu, Lunan; Simeone, Diane M.; Chen, Weiqiang

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Progression of Site-specific Recurrence of Pancreatic Cancer and Implications for Treatment

ANNALS OF SURGERY

IF6.4

2023-10-23

PREAI

Rompen, Ingmar F.; Levine, Jonah; Habib, Joseph R.; Sereni, Elisabetta; Mughal, Nabiha; Hewitt, Daniel Brock; Sacks, Greg D.; Welling, Theodore H.; Simeone, Diane M.; Kaplan, Brian; Berman, Russell S.; Cohen, Steven M.; Wolfgang, Christopher L.; Javed, Ammar A.

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Targeting pancreatic cancer metabolic dependencies through glutamine antagonism

NATURE CANCER

IF28.5

2023-10-09

OAAI

Encarnacion-Rosado, Joel; Sohn, Albert S. W.; Biancur, Douglas E.; Lin, Elaine Y.; Osorio-Vasquez, Victoria; Rodrick, Tori; Gonzalez-Baerga, Diana; Zhao, Ende; Yokoyama, Yumi; Simeone, Diane M.; Jones, Drew R.; Parker, Seth J.; Wild, Robert; Kimmelman, Alec C.

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A Blueprint for a Comprehensive, Multidisciplinary Pancreatic Cancer Screening Program

AMERICAN JOURNAL OF GASTROENTEROLOGY

IF7.6

2023-10-02

PREAI

Fasullo, Matthew; Simeone, Diane; Everett, Jessica; Agarunov, Emil; Khanna, Lauren; Gonda, Tamas

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Surveillance of Individuals at High Risk of Developing Pancreatic Cancer: A Prevalence Meta-analysis to Estimate the Rate of Low-yield Surgery

ANNALS OF SURGERY

IF6.4

2023-09-08

PREAI

Paiella, Salvatore; Secchettin, Erica; Lionetto, Gabriella; Archibugi, Livia; Azzolina, Danila; Casciani, Fabio; Simeone, Diane M.; Overbeek, Kasper A.; Goggins, Michael; Farrell, James; Ponz de Leon Pisani, Ruggero; Tridenti, Maddalena; Corciulo, Maria Assunta; Malleo, Giuseppe; Arcidiacono, Paolo Giorgio; Falconi, Massimo; Gregori, Dario; Bassi, Claudio; Capurso, Gabriele; Salvia, Roberto

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Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment (vol 14, 797, 2023)

NATURE COMMUNICATIONS

IF15.7

2023-07-03

OAAI

Werba, Gregor; Weissinger, Daniel; Kawaler, Emily A.; Zhao, Ende; Kalfakakou, Despoina; Dhara, Surajit; Wang, Lidong; Lim, Heather B.; Oh, Grace; Jing, Xiaohong; Beri, Nina; Khanna, Lauren; Gonda, Tamas; Oberstein, Paul; Hajdu, Cristina; Loomis, Cynthia; Heguy, Adriana; Sherman, Mara H.; Lund, Amanda W.; Welling, Theodore H.; Dolgalev, Igor; Tsirigos, Aristotelis; Simeone, Diane M.

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Research Directions