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The Chemical Probes Portal-2024: update on this public resource to support best-practice selection and use of small molecules in biomedical research Sanfelice, Domenico; Antolin, Albert A.; Crisp, Alisa; Chen, Yi; Bellenie, Benjamin; Brennan, Paul E.; Edwards, Aled; Mueller, Susanne; Al-Lazikani, Bissan; Workman, Paul Share Save
canSAR 2024-an update to the public drug discovery knowledgebase Gingrich, Phillip W.; Chitsazi, Rezvan; Biswas, Ansuman; Jiang, Chunjie; Zhao, Li; Tym, Joseph E.; Brammer, Kevin M.; Li, Jun; Shu, Zhigang; Maxwell, David S.; Tacy, Jeffrey A.; Mica, Ioan L.; Darkoh, Michael; di Micco, Patrizio; Russell, Kaitlyn P.; Workman, Paul; Al-Lazikani, Bissan Share Save
The Stratified Medicine Paediatrics programme for cancers of childhood: Cell free DNA and serial tumour sequencing identifies subtype specific evolution and epigenetic states George, Sally L.; Lynn, Claire; Stankunaite, Reda; Hughes, Debbie; Chalker, Jane; Ahmed, Saira Waqar; Oostveen, Minou; Proszek, Paula; Yuan, Lina; Shaikh, Ridwan; Jamal, Sabri; Tall, Jennifer; Shipley, Janet; Tweddle, Deborah; Marshall, Lynley; Jones, Chris; Gatz, Susanne; Vedi, Aditi; Angelini, Paola; Anderson, John; Cresswell, George; Graham, Trevor A.; Al-Lazikani, Bissan; Kearns, Pamela; Hutchinson, J. Ciaran; Hargrave, Darren; Jacques, Thomas; Hubank, Michael; Sottoriva, Andrea; Chesler, Louis Share Save
HIGH-THROUGHPUT SMALL MOLECULE DRUG SCREENING, TRANSCRIPTOMICS AND INTEGRATIVE AI IDENTIFY TARGETABLE MYC-DEPENDENT THERAPEUTIC VULNERABILITIES IN HIGH-RISK MEDULLOBLASTOMA Llargues-Sistac, Gemma; Taylor, Louisa; Lindsey, Janet; Buttigieg, Marie Claire; Morcavallo, Alaide; Bowers, Chantelle; Che, Harvey; Kwok, Colin; Williamson, Daniel; Anderson, John; Donovan, Laura K.; Hill, Rebecca M.; Al-Lazikani, Bissan; Chesler, Louis; Clifford, Steven C. Share Save
The Virtual Child Gilbertson, Richard J.; Behjati, Sam; Boettcher, Anna-Lisa; Bronner, Marianne E.; Burridge, Matthew; Clausing, Henrick; Clifford, Harry; Danaher, Tracey; Donovan, Laura K.; Drost, Jarno; Eggermont, Alexander M. M.; Emerson, Chris; Flores, Mona G.; Hamerlik, Petra; Jabado, Nada; Jones, Andrew; Kaessmann, Henrick; Kleinman, Claudia L.; Kool, Marcel; Kutscher, Lena M.; Lindberg, Gavin; Linnane, Emily; Marioni, John C.; Maris, John M.; Monje, Michelle; Macaskill, Alexandra; Niederer, Steven; Northcott, Paul A.; Peeters, Elizabeth; Plieger-van Solkema, Willemijn; Preussner, Liane; Rios, Anne C.; Rippe, Karsten; Sandford, Peter; Sgourakis, Nikolaos G.; Shlien, Adam; Smith, Pete; Straathof, Karin; Sullivan, Patrick J.; Suva, Mario L.; Taylor, Michael D.; Thompson, Emma; Vento-Tormo, Roser; Wainwright, Brandon J.; Wechsler-Reya, Robert J.; Westermann, Frank; Winslade, Shannon; Al-Lazikani, Bissan; Pfister, Stefan M. Share Save
The Lancet Commission on prostate cancer: planning for the surge in cases James, Nicholas; Tannock, Ian; N'Dow, James; Feng, Felix; Gillessen, Silke; Ali, Syed Adnan; Trujillo, Blanca; Al-Lazikani, Bissan; Attard, Gerhardt; Bray, Freddie; Comperat, Eva; Eeles, Ros; Fatiregun, Omolara; Grist, Emily; Halabi, Susan; Haran, Aine; Herchenhorn, Daniel; Hofman, Michael S.; Jalloh, Mohamed; Loeb, Stacy; Macnair, Archie; Mahal, Brandon; Mendes, Larissa; Moghul, Masood; Moore, Caroline; Morgans, Alicia; Morris, Michael; Murphy, Declan; Murthy, Vedang; Nguyen, Paul L.; Padhani, Anwar; Parker, Charles; Rush, Hannah; Sculpher, Mark; Soule, Howard; Sydes, Matthew R.; Tilki, Derya; Tunariu, Nina; Villanti, Paul; Xie, Li-Ping Share Save
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Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer Neeb, Antje; Figueiredo, Ines; Bogdan, Denisa; Cato, Laura; Stober, Jutta; Jimenez-Vacas, Juan M.; Gourain, Victor; Lee, Irene I.; Seeger, Rebecca; Muhle-Goll, Claudia; Gurel, Bora; Welti, Jonathan; Nava Rodrigues, Daniel; Rekowski, Jan; Qiu, Xintao; Jiang, Yija; Di Micco, Patrizio; Mateos, Borja; Bielskute, Stase; Riisnaes, Ruth; Ferreira, Ana; Miranda, Susana; Crespo, Mateus; Buroni, Lorenzo; Ning, Jian; Carreira, Suzanne; Braese, Stefan; Jung, Nicole; Graessle, Simone; Swain, Amanda; Salvatella, Xavier; Plymate, Stephen R.; Al-Lazikani, Bissan; Long, Henry W.; Yuan, Wei; Brown, Myles; Cato, Andrew C. B.; de Bono, Johann S.; Sharp, Adam Share Save
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SwarmDeepSurv: swarm intelligence advances deep survival network for prognostic radiomics signatures in four solid cancers Al-Tashi, Qasem; Saad, Maliazurina B.; Sheshadri, Ajay; Wu, Carol C.; Chang, Joe Y.; Al-Lazikani, Bissan; Gibbons, Christopher; Vokes, Natalie I.; Zhang, Jianjun; Lee, J. Jack; Heymach, John, V; Jaffray, David; Mirjalili, Seyedali; Wu, Jia Share Save
canSAR: update to the cancer translational research and drug discovery knowledgebase di Micco, Patrizio; Antolin, Albert A.; Mitsopoulos, Costas; Villasclaras-Fernandez, Eloy; Sanfelice, Domenico; Dolciami, Daniela; Ramagiri, Pradeep; Mica, Ioan L.; Tym, Joseph E.; Gingrich, Philip W.; Hu, Huabin; Workman, Paul; Al-Lazikani, Bissan Share Save
The Chemical Probes Portal: an expert review-based public resource to empower chemical probe assessment, selection and use Antolin, Albert A.; Sanfelice, Domenico; Crisp, Alisa; Fernandez, Eloy Villasclaras; Mica, Ioan L.; Chen, Yi; Collins, Ian; Edwards, Aled; Mueller, Susanne; Al-Lazikani, Bissan; Workman, Paul Share Save
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Individualized Prediction of Drug Response and Rational Combination Therapy in NSCLC Using Artificial Intelligence-Enabled Studies of Acute Phosphoproteomic Changes Coker, Elizabeth A.; Stewart, Adam; Ozer, Bugra; Minchom, Anna; Pickard, Lisa; Ruddle, Ruth; Carreira, Suzanne; Popat, Sanjay; O'Brien, Mary; Raynaud, Florence; de Bono, Johann; Al-Lazikani, Bissan; Banerji, Udai Share Save
Target 2035-update on the quest for a probe for every protein Mueller, Susanne; Ackloo, Suzanne; Al Chawaf, Arij; Al-Lazikani, Bissan; Antolin, Albert; Baell, Jonathan B.; Beck, Hartmut; Beedie, Shaunna; Betz, Ulrich A. K.; Bezerra, Gustavo Arruda; Brennan, Paul E.; Brown, David; Brown, Peter J.; Bullock, Alex N.; Carter, Adrian J.; Chaikuad, Apirat; Chaineau, Mathilde; Ciulli, Alessio; Collins, Ian; Dreher, Jan; Drewry, David; Edfeldt, Kristina; Edwards, Aled M.; Egner, Ursula; Frye, Stephen, V; Fuchs, Stephen M.; Hall, Matthew D.; Hartung, Ingo, V; Hillisch, Alexander; Hitchcock, Stephen H.; Homan, Evert; Kannan, Natarajan; Kiefer, James R.; Knapp, Stefan; Kostic, Milka; Kubicek, Stefan; Leach, Andrew R.; Lindemann, Sven; Marsden, Brian D.; Matsui, Hisanori; Meier, Jordan L.; Merk, Daniel; Michel, Maurice; Morgan, Maxwell R.; Mueller-Fahrnow, Anke; Owen, Dafydd R.; Perry, Benjamin G.; Rosenberg, Saul H.; Saikatendu, Kumar Singh; Schapira, Matthieu; Scholten, Cora; Sharma, Sujata; Simeonov, Anton; Sundstrom, Michael; Superti-Furga, Giulio; Todd, Matthew H.; Tredup, Claudia; Vedadi, Masoud; von Delft, Frank; Willson, Timothy M.; Winter, Georg E.; Workman, Paul; Arrowsmith, Cheryl H. Share Save
PDBe-KB: collaboratively defining the biological context of structural data Varadi, Mihaly; Anyango, Stephen; Armstrong, David; Berrisford, John; Choudhary, Preeti; Deshpande, Mandar; Nadzirin, Nurul; Nair, Sreenath S.; Pravda, Lukas; Tanweer, Ahsan; Al-Lazikani, Bissan; Andreini, Claudia; Barton, Geoffrey J.; Bednar, David; Berka, Karel; Blundell, Tom; Brock, Kelly P.; Maria Carazo, Jose; Damborsky, Jiri; David, Alessia; Dey, Sucharita; Dunbrack, Roland; Fernandez Recio, Juan; Fraternali, Franca; Gibson, Toby; Helmer-Citterich, Manuela; Hoksza, David; Hopf, Thomas; Jakubec, David; Kannan, Natarajan; Krivak, Radoslav; Kumar, Manjeet; Levy, Emmanuel D.; London, Nir; Macias, Jose Ramon; Srivatsan, Madhusudhan M.; Marks, Debora S.; Martens, Lennart; McGowan, Stuart A.; McGreig, Jake E.; Modi, Vivek; Gonzalo Parra, R.; Pepe, Gerardo; Piovesan, Damiano; Prilusky, Jaime; Putignano, Valeria; Radusky, Leandro G.; Ramasamy, Pathmanaban; Rausch, Atilio O.; Reuter, Nathalie; Rodriguez, Luis A.; Rollins, Nathan J.; Rosato, Antonio; Serrano, Luis; Singh, Gulzar; Skoda, Petr; Sorzano, Carlos Oscar S.; Stourac, Jan; Sulkowska, Joanna, I; Svobodova, Radka; Tichshenko, Natalia; Tosatto, Silvio C. E.; Vranken, Wim; Wass, Mark N.; Xue, Dandan; Zaidman, Daniel; Thornton, Janet; Sternberg, Michael; Orengo, Christine; Velankar, Sameer Share Save
Development of a Structured Query Language and Natural Language Processing Algorithm to Identify Lung Nodules in a Cancer Centre Hunter, Benjamin; Reis, Sara; Campbell, Des; Matharu, Sheila; Ratnakumar, Prashanthi; Mercuri, Luca; Hindocha, Sumeet; Kalsi, Hardeep; Mayer, Erik; Glampson, Ben; Robinson, Emily J.; Al-Lazikani, Bisan; Scerri, Lisa; Bloch, Susannah; Lee, Richard Share Save
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JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer Paschalis, Alec; Welti, Jonathan; Neeb, Antje J.; Yuan, Wei; Figueiredo, Ines; Pereira, Rita; Ferreira, Ana; Riisnaes, Ruth; Rodrigues, Daniel Nava; Jimenez-Vacas, Juan M.; Kim, Soojin; Uo, Takuma; Di Micco, Patrizio; Tumber, Anthony; Islam, Md Saiful; Moesser, Marc A.; Abboud, Martine; Kawamura, Akane; Gurel, Bora; Christova, Rossitza; Gil, Veronica S.; Buroni, Lorenzo; Crespo, Mateus; Miranda, Susana; Lambros, Maryou B.; Carreira, Suzanne; Tunariu, Nina; Alimonti, Andrea; Al-Lazikani, Bissan; Schofield, Christopher J.; Plymate, Stephen R.; Sharp, Adam; de Bono, Johann S. Share Save
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