Timothy K. Lu - Publications, H-index & Citations

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Timothy K. Lu

massachusetts institute of technology

74H-index

279Paper Count

2.2WCitation Count

Published Papers 134

Publication Date

Synthetic circuits for cell ratio control

Nature

IF48.5

2026-03-18

OAAI

Bolin An; Tzu-Chieh Tang; Qian Zhang; Teng Wang; Yanyi Wang; Kesheng Gan; Kun Liu; Daniel L. Zhang; Yuzhu Liu; Yu Kui Pan; Min Yu; William M. Shaw; Qianyi Liang; Yaomin Wang; Christopher A. Vaiana; Chunbo Lou; Christopher A. Voigt; Timothy K. Lu; George M. Church; Chao Zhong

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Design principles for adaptive and evolving engineered living materials

Current Opinion in Biotechnology

IF7

2025-12-03

PREAI

Yifan Cui; Mark W Tibbitt; Timothy K Lu; Tzu-Chieh Tang

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Deep generative models design mRNA sequences with enhanced translational capacity and stability

Science

IF45.8

2025-08-28

PREAI

He Zhang; Hailong Liu; Yushan Xu; Haoran Huang; Yiming Liu; Jia Wang; Yan Qin; Haiyan Wang; Lili Ma; Zhiyuan Xun; Xuzhuang Hou; Timothy K. Lu; Jicong Cao

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Rapid Universal Detection of High-Risk and Low-Abundance Microbial Contaminations in CAR-T Cell Therapy (Small Methods 8/2025)

Small Methods

IF9.1

2025-08-27

PREAI

Xiaolin Wu; Joshua Jebaraj Raymond; Yaoping Liu; Alexander Jeremias Odermatt; Wei-Xiang Sin; Denise Bei Lin Teo; Meenubharathi Natarajan; Inn Chuan Ng; Michael E. Birnbaum; Timothy K. Lu; Jongyoon Han; Stacy L. Springs; Hanry Yu

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Mitigation of Doxorubicin Cardiotoxicity With Synergistic miRNA Combinations Identified Using Combinatorial Genetics en masse (CombiGEM)

JACC: CardioOncology

IF12.8

2025-05-13

OAAI

Yasutomi Higashikuni; Colin Platt; Margaret H. Hastings; William C.W. Chen; Justin R.B. Guerra; Takeshi Tokuyama; Fuad Gandhi Torizal; Wenhao Liu; Takumi Obana; Abraham L. Bayer; Hannah Whipple; Alexandra Kuznetsov; Ashish Yeri; Cole Turissini; Robert R. Kitchen; Kota Shibayama; Takayoshi Matsumura; Norihiko Takeda; Hideki Uosaki; Aarti H. Asnani; Timothy K. Lu; Anthony Rosenzweig

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Rapid Universal Detection of High-Risk and Low-Abundance Microbial Contaminations in CAR-T Cell Therapy

Small Methods

IF9.1

2025-03-30

PREAI

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Precision off-the-shelf natural killer cell therapies for oncology with logic-gated gene circuits

CELL REPORTS

IF6.9

2024-05-01

OAAI

Frankel, Nicholas W.; Deng, Han; Yucel, Gozde; Gainer, Marcus; Leemans, Nelia; Lam, Alice; Li, Yongshuai; Hung, Michelle; Lee, Derrick; Lee, Chen -Ting; Banicki, Andrew; Tian, Mengxi; Almudhfar, Niran; Naitmazi, Lawrence; Roguev, Assen; Lee, Seunghee; Wong, Wilson; Gordley, Russell; Lu, Timothy K.; Garrison, Brian S.

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Cas9-assisted biological containment of a genetically engineered human commensal bacterium and genetic elements

NATURE COMMUNICATIONS

IF15.7

2024-03-07

OAAI

Hayashi, Naoki; Lai, Yong; Fuerte-Stone, Jay; Mimee, Mark; Lu, Timothy K.

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A systems-level mass spectrometry-based technique for accurate and sensitive quantification of the RNA cap epitranscriptome

NATURE PROTOCOLS

IF16

2023-08-11

PREAI

Wang, Jin; Chew, Bing Liang Alvin; Lai, Yong; Dong, Hongping; Xu, Luang; Liu, Yu; Fu, Xin-Yuan; Lin, Zhenguo; Shi, Pei-Yong; Lu, Timothy K.; Luo, Dahai; Jaffrey, Samie R.; Dedon, Peter C.

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BioAutoMATED: An end-to-end automated machine learning tool for explanation and design of biological sequences

CELL SYSTEMS

IF7.7

2023-06-01

OAAI

Valeri, Jacqueline A.; Soenksen, Luis R.; Collins, Katherine M.; Ramesh, Pradeep; Cai, George; Powers, Rani; Angenent-Mari, Nicolaas M.; Camacho, Diogo M.; Wong, Felix; Lu, Timothy K.; Collins, James J.

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Off-the-Shelf CAR-NK cells engineered to express calibrated release IL-15 exhibit enhanced persistence and anti-tumor activities

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Lee, Chen-Ting; Hung, Michelle; Banicki, Andrew; Song, Wenqi; Almudhfar, Niran; Kaveri, Deepika; Wong, Priscilla; Naitmazi, Lawrence; Guzman, Marcela; Lam, Alice; Yucel, Gozde; Lu, Timothy; Junca, Alba G.; Garrison, Brian; Lee, Philip

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Preclinical development of SENTI-202, an off-the-shelf logic gated CAR-NK cell therapy, for the treatment of CD33/FLT3+hematologic malignancies including AML

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Gonzalez, Alba; Hong, Enping; Yucel, Gozde; Leitner, Elizabeth; Chinta, Pearley; Deng, Han; Li, Ian; Lam, Alice; Bakir, Abla; Lee, Brandon; Chakraborty, Papia; Blanco, Carmina; Lee, Chen-Ting; Almudhfar, Niran; Tian, Mengxi; Song, Wenqi; Banicki, Andrew; Contreras, Otto; Gieldin, Martin; Garrison, Brian; Lu, Timothy K.; Rajangam, Kanya

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SENTI-301A, an off-the-shelf multi-armed preclinical CAR-NK cell therapy, for the treatment of GPC3 expressing tumors

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Ayala, Marcela Guzman; Kaveri, Deepika; Hong, Enping; Leitner, Elizabeth; Wong, Priscilla; Ponek, Ronni; Naitmazi, Lawrence; Chinta, Pearley; Gorman, Wesley; Tian, Mengxi; Almudhfar, Niran; Lee, Kelly; Frankel, Nicholas; Junca, Alba Gonzalez; Gordley, Russell; Lee, Philip; Lu, Timothy; Rajangam, Kanya

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Optimization of Host Cell-Compatible, Antimicrobial Peptides Effective against Biofilms and Clinical Isolates of Drug-Resistant Bacteria

ACS INFECTIOUS DISEASES

IF3.8

2023-03-24

OAAI

Ghimire, Jenisha; Hart, Robert J.; Soldano, Anabel; Chen, Charles H.; Guha, Shantanu; Hoffmann, Joseph P.; Hall, Kalen M.; Sun, Leisheng; Nelson, Benjamin J.; Lu, Timothy K.; Kolls, Jay K.; Rivera, Mario; Morici, Lisa A.; Wimley, William C.

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A Threshold-Based Bioluminescence Detector With a CMOS-Integrated Photodiode Array in 65 nm for a Multi-Diagnostic Ingestible Capsule

IEEE JOURNAL OF SOLID-STATE CIRCUITS

IF5.6

2023-03-01

PREAI

Liu, Qijun; Jimenez, Miguel; Inda, Maria Eugenia; Riaz, Arslan; Zirtiloglu, Timur; Chandrakasan, Anantha P.; Lu, Timothy K.; Traverso, Giovanni; Nadeau, Phillip; Yazicigil, Rabia Tugce

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Ultra-lightweight living structural material for enhanced stiffness and environmental sensing

MATERIALS TODAY BIO

IF10.2

2023-02-01

OAAI

Park, Heechul; Schwartzman, Alan F.; Tang, Tzu-Chieh; Wang, Lei; Lu, Timothy K.

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Full-colour Jabuticaba-like nanostructures via the multiplex and orthogonal self-assembly of protein-conjugated quantum dots with engineered biofilms

MATERIALS HORIZONS

IF10.7

2023-01-01

PREAI

Deng, Zhengtao; Chen, Allen Y. Y.; Zakeri, Bijan; Zhong, Chao; Lu, Timothy K. K.

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Enhancing nutritional niche and host defenses by modifying the gut microbiome

MOLECULAR SYSTEMS BIOLOGY

IF7.7

2022-11-15

OAAI

Sun, Qing; Vega, Nic M.; Cervantes, Bernardo; Mancuso, Christopher P.; Mao, Ning; Taylor, Megan N.; Collins, James J.; Khalil, Ahmad S.; Gore, Jeff; Lu, Timothy K.

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SENTI-401, AN ALLOGENEIC LOGIC-GATED AND MULTIARMED CAR-NK CELL THERAPY FOR THE TREATMENT OF CEA-EXPRESSING SOLID TUMORS WITH ENHANCED SELECTIVITY AND EFFICACY

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2022-11-07

OAAI

Junca, Alba Gonzalez; Frankel, Nicholas; Morvan, Maelig; Roguev, Assen; Hung, Michelle; Gordley, Russell; Palermo, Miguel; Santomaso, Tyler; Chinta, Pearley; Sotelo, Aldo; Gainer, Marcus; Lee, Derrick; Hua, Tony; Banicki, Andrew; Tian, Mengxi; Almudhfar, Niran; Contreras, Atahualpa; Lee, Chen-Ting; Lu, Timothy

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A synthetic transcription platform for programmable gene expression in mammalian cells

NATURE COMMUNICATIONS

IF15.7

2022-10-18

OAAI

Chen, William C. W.; Gaidukov, Leonid; Lai, Yong; Wu, Ming-Ru; Cao, Jicong; Gutbrod, Michael J.; Choi, Gigi C. G.; Utomo, Rachel P.; Chen, Ying-Chou; Wroblewska, Liliana; Kellis, Manolis; Zhang, Lin; Weiss, Ron; Lu, Timothy K.

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Research Directions