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G

Guy S. Salvesen

sanford burnham prebys

119H-index
383Paper Count
7.3WCitation Count
Published Papers 183
Publication Date
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Cooperation and constraint: the complex association of caspase-8 and cFLIP
errCell Death and Differentiation
IF15.4
err2026-07-27
err0
errOAAI
errBetsaida Bibo-Verdugo; Guy S. Salvesen
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Synthesis and Characterization of ULK1/2 Kinase Inhibitors That Inhibit Autophagy and Upregulate Expression of Major Histocompatibility Complex I for the Treatment of Non-Small Cell Lung Cancer
errACS Chemical Biology
IF3.8
err2026-02-12
err0
PREAI
errFabiana Izidro A. L. Layng; Huiyu Ren; Nicole A. Bakas; Dhanya R. Panickar; Lester J. Lambert; Maria Celeridad; Jiaqian Wu; Laurent De Backer; Preeti Chandrachud; Allison S. Limpert; Mitchell Vamos; Apirat Chaikuad; Betsaida B. Verdugo; Patrick M. Hagan; Sonja N. Brun; Lutz Tautz; Stefan Knapp; Reuben J. Shaw; Guy S. Salvesen; Douglas J. Sheffler; Nicholas D. P. Cosford
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errSave
Differential specificity of SARS-CoV-2 main protease variants on peptide versus protein-based substrates
errFEBS JOURNAL
IF4.2
err2023-11-03
err0
errOAAI
errRocho, Fernanda R.; Snipas, Scott J.; Shamim, Anwar; Rut, Wioletta; Drag, Marcin; Montanari, Carlos A.; Salvesen, Guy S.
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errSave
Cell organelles are retained inside pyroptotic corpses during inflammatory cell death
errBIOSCIENCE REPORTS
IF4.7
err2023-10-27
err2
errOAAI
errHempel, Anne; D'Osualdo, Andrea; Snipas, Scott J.; Salvesen, Guy S.
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errSave
Caspase-9 inhibition confers stronger neuronal and vascular protection compared to VEGF neutralization in a mouse model of retinal vein occlusion
errFRONTIERS IN NEUROSCIENCE
IF3.2
err2023-06-28
err5
errOAAI
errAvrutsky, Maria I.; Chen, Claire W.; Lawson, Jacqueline M.; Snipas, Scott J.; Salvesen, Guy S.; Troy, Carol M.
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errSave
Oxidation of caspase-8 by hypothiocyanous acid enables TNF-mediated necroptosis
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-06-01
err7
errOAAI
errBozonet, Stephanie M.; Magon, Nicholas J.; Schwartfeger, Abigail J.; Konigstorfer, Andreas; Heath, Sarah G.; Vissers, Margreet C. M.; Morris, Vanessa K.; Gobl, Christoph; Murphy, James M.; Salvesen, Guy S.; Hampton, Mark B.
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errSave
Caspase mechanisms in the regulation of inflammation
errMOLECULAR ASPECTS OF MEDICINE
IF10.3
err2022-12-01
err20
errOAAI
errBibo-Verdugo, Betsaida; Salvesen, Guy S.
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Gain of function of a metalloproteinase associated with multiple myeloma, bicuspid aortic valve, and Von Hippel-Lindau syndrome
errBIOCHEMICAL JOURNAL
IF4.3
err2022-07-21
err1
errOAAI
errSnipas, Scott J.; Jappelli, Roberto; Torkamani, Ali; Paternostro, Giovanni; Salvesen, Guy S.
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errSave
Resurrection of an ancient inflammatory locus reveals switch to caspase-1 specificity on a caspase-4 scaffold
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-06-01
err5
errOAAI
errBibo-Verdugo, Betsaida; Joglekar, Isha; Giridhar, Mithun N. Karadi; Ramirez, Monica L.; Snipas, Scott J.; Clark, A. Clay; Poreba, Marcin; Salvesen, Guy S.
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errSave
Evolutionary loss of inflammasomes in the Carnivora and implications for the carriage of zoonotic infections
errCELL REPORTS
IF6.9
err2021-08-01
err22
errOAAI
errDigby, Zsofi; Tourlomousis, Panagiotis; Rooney, James; Boyle, Joseph P.; Bibo-Verdugo, Betsaida; Pickering, Robert J.; Webster, Steven J.; Monie, Thomas P.; Hopkins, Lee J.; Kayagaki, Nobuhiko; Salvesen, Guy S.; Warming, Soren; Weinert, Lucy; Bryant, Clare E.
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errSave
Evaluation of the effects of phosphorylation of synthetic peptide substrates on their cleavage by caspase-3 and-7
errBIOCHEMICAL JOURNAL
IF4.3
err2021-06-18
err6
errOAAI
errMaluch, Izabela; Grzymska, Justyna; Snipas, Scott J.; Salvesen, Guy S.; Drag, Marcin
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errSave
NETosis occurs independently of neutrophil serine proteases
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2020-12-01
err27
errOAAI
errKasperkiewicz, Paulina; Hempel, Anne; Janiszewski, Tomasz; Kolt, Sonia; Snipas, Scott J.; Drag, Marcin; Salvesen, Guy S.
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errSave
Multiplexed Probing of Proteolytic Enzymes Using Mass Cytometry-Compatible Activity-Based Probes
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2020-09-01
err30
errOAAI
errPoreba, Marcin; Groborz, Katarzyna M.; Rut, Wioletta; Pore, Milind; Snipas, Scott J.; Vizovisek, Matej; Turk, Boris; Kuhn, Peter; Drag, Marcin; Salvesen, Guy S.
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errSave
Extended subsite profiling of the pyroptosis effector protein gasdermin D reveals a region recognized by inflammatory caspase-11
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2020-08-01
err40
errOAAI
errBibo-Verdugo, Betsaida; Snipas, Scott J.; Kolt, Sonia; Poreba, Marcin; Salvesen, Guy S.
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errSave
Engineering caspase 7 as an affinity reagent to capture proteolytic products
errFEBS JOURNAL
IF4.2
err2020-07-11
err0
errOAAI
errRazai, Amir S.; Snipas, Scott J.; Poreba, Marcin; Fasci, Domenico; Salvesen, Guy S.
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errSave
Endothelial activation of caspase-9 promotes neurovascular injury in retinal vein occlusion (vol 11, 3173, 2020)
errNATURE COMMUNICATIONS
IF15.7
err2020-07-09
err3
errOAAI
errAvrutsky, Maria I.; Ortiz, Crystal Colon; Johnson, Kendra V.; Potenski, Anna M.; Chen, Claire W.; Lawson, Jacqueline M.; White, Alexandra J.; Yuen, Stephanie K.; Morales, Fatima N.; Canepa, Elisa; Snipas, Scott; Salvesen, Guy S.; Jean, Ying Y.; Troy, Carol M.
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Design, synthesis, andin vitroevaluation of aza-peptide aldehydes and ketones as novel and selective protease inhibitors
errJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
IF5.4
err2020-07-07
err8
errOAAI
errCorrigan, Thomas S.; Diaz, Leilani M. Lotti; Border, Sarah E.; Ratigan, Steven C.; Kasper, Kayla Q.; Sojka, Daniel; Fajtova, Pavla; Caffrey, Conor R.; Salvesen, Guy S.; McElroy, Craig A.; Hadad, Christopher M.; Ekici, Ozlem Dogan
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errSave
Noninvasive optical detection of granzyme B from natural killer cells with enzyme-activated fluorogenic probes
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2020-07-01
err27
errOAAI
errJaniszewski, Tomasz; Kolt, Sonia; Kaiserman, Dion; Snipas, Scott J.; Li, Shuang; Kulbacka, Julita; Saczko, Jolanta; Bovenschen, Niels; Salvesen, Guy; Drag, Marcin; Bird, Phillip, I; Kasperkiewicz, Paulina
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errSave
Endothelial activation of caspase-9 promotes neurovascular injury in retinal vein occlusion
errNATURE COMMUNICATIONS
IF15.7
err2020-06-23
err33
errOAAI
errAvrutsky, Maria I.; Ortiz, Crystal Colon; Johnson, Kendra V.; Potenski, Anna M.; Chen, Claire W.; Lawson, Jacqueline M.; White, Alexandra J.; Yuen, Stephanie K.; Morales, Fatima N.; Canepa, Elisa; Snipas, Scott; Salvesen, Guy S.; Jean, Ying Y.; Troy, Carol M.
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errSave
Development of a therapeutic anti-HtrA1 antibody and the identification of DKK3 as a pharmacodynamic biomarker in geographic atrophy
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2020-04-28
err35
errOAAI
errTom, Irene; Pham, Victoria C.; Katschke, Kenneth J.; Li, Wei; Liang, Wei-Ching; Gutierrez, Johnny; Young, Andrew Ah; Figueroa, Isabel; Eshghi, Shadi Toghi; Lee, ChingWei, V; Kanodia, Jitendra; Snipas, Scott J.; Salvesen, Guy S.; Lai, Phillip; Honigberg, Lee; Campagne, Menno van Lookeren; Kirchhofer, Daniel; Baruch, Amos; Lill, Jennie R.
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Research Directions

No research directions
Co-authors
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